Objective To study the effects of early rehabilitation with stroke patients by applying Snyder hope theory in clinical nursing. Methods A total of 76 acute stroke patients from Henan Province Hospital of Traditional Chinese Medicine were divided into two groups by random digits table method:experimental group and control group, 38 cases in each group. The final effective cases were 72 and 36 cases in each. The control group received routine care, while those in the experimental group accepted nursing intervention with Snyder hope theory based on routine puncture care for 4 weeks. Herth Hope Index(HHI), National Institute of Health Stroke Scale(NIHSS), Barthel Index(BI) and adherence score before and after 4 weeks were evaluated and compared between 2 groups. Results Before intervention and 4 weeks after intervention, the experimental group of patients with hope level score respectively (31.61 ± 1.95), (40.67 ± 4.01) points, NIHSS scores respectively (18.27 ± 5.31), (10.41 ± 4.21) points, BI scores respectively (37.19 ± 3.31), (46.12 ± 3.51) points, and adherence of functional exercise scores (0.97 ± 0.31), (2.81 ± 0.52) points. The differences were statistically significant (t=17.765-52.571, all P<0.01). There were statistically significant differences with hope level, NIHSS score, BI score before intervention and 4 weeks after intervention in the control group (t=5.435, 4.929, 11.067, all P<0.01), except for adherence of functional exercise scores (t=1.220, P=0.231) in the control group, but the change not as the experimental group. Compared with the control group, there were statistically significant in the score of hope level, NIHSS score, BI score and adherence of functional exercise with the experimental group after intervention ( t=6.030-10.690, all P<0.01). Conclusions The nursing with Snyder hope theory can promote the progress of early rehabilitation of acute stroke patients as well as the patients′exercise adherence.

The iodine deficiency disorders surveillances were performed in different historical periods according to different surveillance plans in China as various monitoring purposes.Compared with other editions of surveillance plan,the biggest changes were to observe the urinary iodine level,the salt iodine level and the goiter rate in children and pregnant women in the county level in this National Iodine Deficiency Disorders Surveillance Plan (the 2016 edition).In this paper,the implementation details on this surveillance plan were further interrelated,which would play an instrumental role for the staff in iodine deficiency disorders prevention and control.

Type 2 diabetes is a heterogeneous disorder caused by concomitant impairment of β-cell dysfunction,the hallmark of which is a series of abnormalities of histology and pathophysiology.The impairment of insulin secretion of type 2 diabetes is related to insulin deficiency and abnormal β-cell secretion.The progressive deterioration in β-cell function and mags in type 2 diabetes are the driving forces for the disease progression.

The assessment of pituitary function makes hormone replacement more timely for hypopituitarism after surgical procedure in patients with pituitary adenoma.However,there were only less than 50％ patients receiving this assessment in the current clinical practice.Only by means of the cooperation between endocrinologists and neurosurgeons and the close contact between doctors from both tertiary and primary hospitals will reach the goal of the patient-centered treatment and appropriately improve the defective therapy of the pituitary adenoma.

The failure of islet β cell is the core pathogenic mechanism of diabetes,which is also the key target for type 2 diabetic mellitus treatment.A large amount of basic and clinical researches have been confirmed that glucagon like peptide-1 and its analogue liraglutide have abilities to significantly improve islet β cell function besides the glucose-dependent lowering hyperglycemia effects.Furthermore,liraglutide is approved to improve β cell function,thus providing a new choice for treatment of type 2 diabetes.

Objective To study the applied value of invasive arterial blood pressure monitoring in the diagnose and treatment of coronary artery intervention. Methods The dynamic changes of ECG, the non-invasive blood pressure, the invasive arterial blood pressure monitoring and the clinical performance were ob-served in 163 patients in the process of coronary artery intervention (CAI). Then the invasive arterial blood pressure change and the non-invasive blood pressure change were compared. Results The change rates of invasive arterial blood pressure were higher than that of non-invasive arterial blood pressure. The difference of both changes had statistical significance. The invasive blood pressure decreased and wave forms changed in 26 cases. These reflected sensitively the patients' condition and the issues in the process of CAI. Conclusions To strengthen the invasive arterial blood pressure monitoring can improve the success rate of CAI more effec-tively and reduce the complication.

Tumor dormancy is a well-known clinical phenomenon and the underlying mechanisms are poorly understood.It has been speculated that one of the major factors accounting for the dormant behavior is impaired angiogenesis.As stimuli result in the imbalanced concentration between the pro-angiogenic factors and anti-angiogenic factors,the tumors would escape from dormancy.However,why a dormant(silent)tumor be-comes angiogenic has not been explained and the molecular events that participate in it are under investigation.Despite all that,anti-angiogenic therapy is a very promising strategy to induce tumor dormancy.

Emergence delirium (ED) is a complex of perceptual disturbances and psychomotor agitation that occurs most commonly in preschool-aged children in the early postanesthetic period.Although these events are often short lived,they increase the risk of self-injury,require additional nursing staff and can increase medical care costs,all of which are causes for concern.A variety of anesthesia-,surgery-,patient-,and adjunct medication-related factors have been suggested to play a potential role in the development of such an event.The risk of ED is lowest when propofol is used as a single-agent anesthetic compared with sevoflurane-based anesthetics.Adjunctive agents can be rated in the following order of most effective to least effective interventions:dexmedetomidine,fentanyl,ketamine,clonidine.This review summarizes the factors that may predict ED and provides an intervention algorithm to guide effective prevention and treatment.

In clinical medical school,disharmony between teaching and learning has been existing which affects the teaching quantity as well as the cultivation of talents.Personal suggestions about the ways to deal with these problems are given in this paper.

BACKGROUND:Stem cel transplantation is a promising treatment for type 1 diabetes mel itus. Adipose-derived mesenchymal stem cel s have become another hotspot fol owing bone marrow mesenchymal stem cel s.
OBJECTIVE:To investigate the therapeutic effect of adipose-derived mesenchymal stem cel transplantation on type 1 diabetes in a rat model.
METHODS:Forty-five Sprague-Dawley rats were randomized into normal, model and cel transplantation. Animal model of type 1 diabetes was made in the latter two groups through intraperitoneal injection of streptozotocin. Seven days after modeling, rats in the three groups were given intraperitoneal injection of normal saline, serum-free DMEM or adipose-derived mesenchymal stem cel suspension, respectively. Two weeks after injection, body mass, blood glucose level, insulin secretion and PDX-1 mRNA in the pancreatic tissue of rats were monitored and detected in the three groups.
RESULTS AND CONCLUSION:After modeling, the body mass of rats were lowered, and increased gradual y in the cel transplantation group at 2 weeks after cel transplantation, but it was stil decreased in the model group. Compared with the normal group, the fasting blood glucose level was significantly higher in the model group (P<0.05), but it was reduced significantly after cel transplantation (P<0.05). Compared with the normal group, the insulin level was reduced significantly in the model group (P<0.05), but it was increased significantly after cel transplantation (P<0.05). Highest and lowest PDX-1 mRNA expressions were obtained in the normal and model groups, respectively;and there was a significant difference between groups (P<0.05). Al these findings show that adipose-derived mesenchymal stem cel transplantation relieves hyperglycemia in rats by promoting the expression of PDX-1 in the rat pancreatic tissue.