1.Comparison of one point and two points brachial plexus block below the elbow surgery anesthesia
Chinese Journal of Primary Medicine and Pharmacy 2016;23(16):2523-2524,2525
Objective To compare one point and two points brachial plexus block anesthesia effect below the elbow surgery anesthesia.Methods 70 patients with elective elbow following orthopedic surgery were randomly divid-ed into two points group (group A)and one point group (group B)by random number table,each group had 35 cases.Analgesic effect of anesthesia was compared.The toxic reactions,neurovascular damage and other vascular complications of anesthesia were observed.Results The effective rate and incidence rate of complication of group A were 97.1% and 8.6%,those of group B were 77.1% and 11.4%(χ2 =6.248,0.159).The analgesic effect of group A was significantly better than group B (P <0.05),the incidence of anesthetic complications between the two groups showed no significant difference (P >0.05).Conclusion Axillary brachial plexus block of two points simul-taneous injection has better analgesic effect,block more perfect,it is the first selection of orthopaedics below the elbow surgery anesthesia method.
2.Comparison of 13 emergency biochemical test items′measurement uncertainty between two biochemical analyzers
International Journal of Laboratory Medicine 2015;(22):3268-3270
Objective To investigate the method and application of measurement uncertainty in clinical biochemical tests .Meth-ods The synthetic uncertainty and expanding uncertainty of 13 emergency biochemical tests items were compared between Hitachi 7600 and Beckman DXC800 automatic biochemical analyzer by usingmodel method.The test items included aspartate aminotrans-ferase ,total protein ,albumin ,glucose ,urea ,creatinine ,creatine kinase ,lactate dehydrogenase ,amylase ,potassium ,sodium ,calcium and chloride .Results Measurement uncertainty of aspartate aminotransferase and lactate dehydrogenase were 3 .66% and 3 .51%respectively ,which were the top two on Hitachi 7600 analyzer ;measurement uncertainty of calcium and creatinine were 4 .00% and 3 .90% respectively ,which were the top two on Beckman DXC800 .Compared between the two analyzers ,the test item with the lar-gest difference of measurement uncertainty was sodium(2 .62% ) ,and the second was creatinine(2 .40% ) .The difference of meas-urement uncertainty of the 13 emergency biochemical test items between the two analyzers were relatively small .Conclusion The two analyzer both have good performance ,Model methodis suitable for the evaluation of regular test items′measurement uncer-tainty in clinical biochemical laboratory .
3.Surveillance on the quality of disinfection and sterilization among medical institutes in Xi’an in 201 1-2013
Chinese Journal of Infection Control 2014;(11):681-684
Objective To investigate the status of disinfection and sterilization quality of different levels of medical institu-tes in Xi’an,and improve the management level of disinfection and sterilization of medical institutes. Methods Disinfection and sterilization efficacy of 69 medical institutes were monitored and evaluated according to Standardization for Disinfec-tionTechniques (2002 edition)and Sanitary Standards for Hospital Disinfection (GB15982-1995). Results From 2011 to 2013,2 224 specimens were tested,1 766 (79.41% )were qualified.The qualified rate of tertiary medical institutes was higher than second and below medical institutes (83.67% vs 77.50% ,P= 0.001),the qualified rate between public medical institutes and private medical institutes was not statistically different (79 .64% vs 78 .20% , P= 0.532),the qualified rate of comprehensive medical institutes was higher than specialized medical institutes (80.18% vs 74.92% ,P= 0.030). Of different detected specimens,the qualified rates of disinfectant in use and pressure steam sterilizers (including test pack and process challenge device)were higher (98.46% ,100.00% ,and 98.06% respectively),while the hands of health care workers (HCWs)and glutaraldehyde were lower(58.48% and 43 .28% respectively).Conclusion Disinfection and sterilization quality in different medical institutes in Xi’an is dif-ferent,and different disinfected and sterilized objects are also varied .It is necessary to intensify the management of hand hygiene of HCWs and concentration of glutaraldehyde.
4.Value of serum miR-155 in the diagnosis and prognosis of pancreatic cancer
Xiaogang WANG ; Zhong TONG ; Gang JIN
Chinese Journal of Hepatobiliary Surgery 2015;21(3):189-193
Objective To investigate the diagnostic and prognostic value of serum miR-155 for pancreatic cancer.Methods A total of 110 pancreatic cancer patients,70 chronic pancreatitis and 58 healthy individuals who admitted to the First People's Hospital of Hefei between January 2009 and August 2013 were prospectively enrolled.Their serum miR-155 levels were detected by real-time PCR.The receiver operating characteristic curve was employed to estimate the diagnostic accuracy of miR-155 for pancreatic cancer.Correlations between miR-155,carbohydrate antigen 19-9 (CA 19-9) and TNM stages were analyzed.The Kap1an-Meier approach and the Cox model were used to assess the prognostic value of miR-155 for pancreatic cancer.Results Pancreatic cancer patients had significantly higher serum miR-155 when compared either with chronic pancreatitis patients or healthy individuals (P < 0.05 for both).The areas under the receiver operating characteristic curve were 0.82 (95% CI:0.75 ~ 0.88) for miR-155,and 0.88 (95% CI:0.82 ~0.93) for miR-155 combined with CA19-9.MiR-155 increased as the TNM stages advanced,and it was positively correlated with CA 19-9 (R2 =0.22,P < 0.05).MiR-155 ≥ 1.46 △CT was independently associated with pancreatic cancer mortality,with a hazard ration of 2.88 (95% CI:1.26 ~ 6.58).Conclusion Serum miR-155 is a useful biomarker for diagnosis and prognosis of pancreatic cancer.
5.Establishment of the assessment system for blood transfusion and discussions on the method of clinical transfusion monitor
Xiaogang DU ; Lirong WANG ; Honglin WU
Chinese Journal of Hospital Administration 2014;30(1):42-45
Objective Discuss the methodology and significance of clinical transfusion assessment,establish an effective evaluation system for blood transfusion,identify rational indexes for the evaluation,and promote quality of clinical transfusion.Methods Development of the clinical blood transfusion assessment regulations,tightened blood transfusion approval system,enhanced medical record check for blood transfusion,better statistics for the data collected,and analysis of data in 2012 to compare changes in blood volume before and after tighter management in place.These efforts aim at improving the assessment system for optimal clinical blood transfusion.Results Compared to Jan.-June in 2012,patients discharged and surgical cases in Dec.of the same year dropped 2.15% and 0.73% respectively.However,the volume of blood transfusion decreased 22.7%,the percentage of blood transfusion for inpatients decreased from 8.78% to 7.17%,and the average use of blood for inpatients decreased from 0.73U to 0.57U.Conclusion Reasonable and scientific assessment for blood transfusion and better clinical blood use management can improve blood transfusion therapeutic efficacy and save blood resources.
6.Effect of B_2O_3 and P_2O_5 on fluorosilicic mica glass-ceramic sintering process
Shun WU ; Zhongyi WANG ; Xiaogang CAO
Journal of Practical Stomatology 1996;0(02):-
Objective: To study the effect of B 2O 3 and P 2O 5 on fluorosilicic mica glass-ceramic sintering process.Methods: Six sets of K 2O-MgO-SiO 2-MgF glass were prepared by using B 2O 3 and P 2O 5as sintering aid respectively. Green bodies of the glass powder were formed by gelcasting and sintered at 800,850,900,950 and 1 000 ℃ for 6 h respectively. The sintering and crystallization behavior were studied by thermal shrinkage , X-ray diffraction (XRD) and SEM.Results:The shrinkage rate of the glass with 2% B 2O 3 and P 2O 5 was the highest ,while that of the glass with 5% P 2O 5 the lowest. The size of the precipitated crystal from the glass ceramics containing 2% B 2O 3 and 2% P 2O 5 was bigger.Conclusion:The density and shrinkage measurements of the sintered bodies show that the glass powder of pure K 2O-MgO-SiO 2-MgF system has poor sinterability, while minor addition (
7.Clinical Observation of Huoxin Capsule on Angina Pectoris of Coronary Heart Disease
Zhen LIU ; Xiaoguang YAN ; Xiaogang WANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
0.05). After treating, the accumulating points of syndrome of the treatment group dropped more, the treatment group was superior to the control group. Conclusions The curative effects of Huoxin capsule on angina of coronary arheroselerosis heart disease is exact. It can take effect quickly and improve the whole symptom of the patients noticeably.
8.CERVICAL INTRAMEDULLARY SPINAL TERATOMA: A REPORT OF 2 CASES AND A LITERATURE REVIEW
Xiaogang WANG ; Dongyuan CHENG ; Baina XU
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
To discuss the clinical situation and treatment of cervical intramedullary spinal teratoma, two cases of it in our department were presented, and the related literatures were reviewed. A concomitant anomaly of the cervical vertebral canal was found to be accompanied by cervical intramedullary spinal teratoma. MRI showed the tumors with mixed signal intensity. During operation the tumor was found to have both cysts and hard bony nodules. It was very difficult to remove the total tumor. It is concluded that the plain film of cervical vertebra and cervical spine MRI are sensitive to differentiate teratomas from other tumors. Surgery should be the first choice for treatment.
9.ULTRASOUND AND MRI ANALYSIS OF HUMAN CAROTID PLAQUE COMPOSITIONS
Xiaogang WANG ; Dingbiao ZHOU ; Junla LI
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
To correlate the ultrasound and MR imaging of carotid atherosclerotic plaque with its histologic compositions,20 patients(22 lesions) scheduled for carotid endarterectomy were examined by B mode ultrasound and MRI preoperatively. The specimens were also examined postoperatively and the images of carotid plaque were recorded. The transverse pathological sections of plaques were made and matched with images of ultrasound and MRI. 256 gray scale ultrasound densitometric analysis of carotid plaque compositions was performed. Ultrasonic density of calcium, fibrous tissue, hemorrage/thrombus and lipid deposits was (89?12), (53?8), (37?6) and (39?3) respectively in vivo , and was (168?11), (136?12), (85?12) and (89?10) respectively in vitro . In vivo relative signal intensities of calcium, fibrous tissue, old hemorrhage/thrombus and lipid deposits were low, equal, equal and very high respectively on T 1 W MR image, and very low, equal, high and high respectively on PDW MR image, and low, equal or slightly high, high and high respectively on T 2 W MR image. Signal intensities of plaque contents ex vivo were correlated to signal intensities in vivo. Densitometric analysis of ultrasound images of carotid plaques can quantify possible components of plaque, and MRI has the feasibility to identify the components of plaque.
10.DISTRIBUTION OF MAST CELLS IN ATHEROSCLEROTIC LESIONS OF HUMAN CAROTID ARTERIES
Xiaogang WANG ; Dingbiao ZHOU ; Weidon YIN
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
To study the distribution of two different phenotype mast cells in atherosclerotic lesions of human carotid arteries, 32 samples of endarterectomy and 10 autopsies of normal carotid specimens were fixed and embeded in paraffin, sections were stained with hematoxylin-eosin, toluidine blue,monoclonal antibodies against the two major proteases of mast cells(tryptase and chymase) and monoclonal antibodies against CD-3 of T lymphocytes and CD-68 of macrophages. The quantity,distribution and degranule of two different phenotype mast cells in atherosclerotic lesions of human carotid arteries were investigated,and the ratio of mast cells to T lymphocytes and macrophages in atherosclerotic lesions was calculated. The density(cells/mm 2 ) of mast cells in shoulder region of plaque(6 3?4 0) was much higher than that in normal intima,cap and core region(1 3?2 3,2 3?2 6,2 2?3 7) .The proportion of chymase-containing mast cells to tryptase-containing mast cells was 0 36,0 51,0 47 and 0 39 respectively in normal intima,cap,core and shoulder region of plaque.The propotion of degranulated mast cells was the highest in shoulder region of plaque(65%).The ratios of mast cells to T lymphocytes and to macrophages were 0 25 and 0 14 respectively in shoulder region of plaques.Light microscopic studies of mast cells revealed that mast cells were more commonly observed in thrombus and around calcification and blood vessels of plaque.Mast cells play a role in the formation of plaque,and participate in the destabilization of plaque.