1.Critical Discourse Analysis in Doctor-patient Discourse in Chinese Medical Clinic
Chinese Medical Ethics 2015;(1):8-12
Critical Discourse Analysis ( CDA) attempts to uncover the inequality in social reality and the way language presents power and ideology through the analysis of language features. Systemic functional linguistics ( SFL) focuses on the dialectical relationship between language and society and has been considered an important approach and theoretical basis to CDA. Doctors in Chinese medical clinic follow the Four Diagnostic Methods, within which the inquiry diagnosis strongly shows the fact that doctor and patient clash over the ideology and strug-gle for the power via language. The study carries out CDA on doctor-patient discourse in Chinese medical clinic within the theoretical framework of SFL from four aspects including nominalization, classification, transitivity and mood, which verifies that the language is the product of asymmetric power between doctor and patient. It is hoped that the paper would provide insight into CDA on doctor-patient discourse and would be of theoretical meaning.
2.Treatment of Child Diarrhea by Ginger-partitioned Moxibustion plus Tuina: A Report of 52 Cases
Journal of Acupuncture and Tuina Science 2003;1(6):20-21
Treated 52 cases of child diarrhea with ginger-partitioned moxibustion plus Tuina, after three treatments, all the patients are cured.
3.Decompressive craniectomy and temporal muscle sticking therapy of cerebral infarction:experience and problems
Chinese Journal of Tissue Engineering Research 2014;(11):1793-1798
BACKGROUND:A surgery can relieve the increased intracranial pressure, brain tissue edema, and brain stem compression in patients with massive cerebral infarction, and reduce the risk of serious complications, provide more time for medical treatment, and decrease the mortality and disability rate.
OBJECTIVE:To investigate the clinical value of decompressive craniectomy plus temporal muscle sticking therapy of cerebral infarction.
METHODS:A retrospective analysis was performed among the clinical data of 37 cerebral infarction patients, including 24 males and 13 females, they aged 10-55 years old. After decompressive craniectomy plus temporal muscle sticking therapy, the involved patients were fol owed up. The prognosis was evaluated according to the Glasgow Outcome Scale, as excel ent, good, moderate, none, and poor.
RESULTS AND CONCLUSION:At 6 months of fol ow-up, the total efficiency of surgical treatment in 37 patients was up to 89%, including excel ent in 5 cases (14%), good in 15 cases (41%), moderate in 13 cases (35%), none in 4 cases (11%). No cases exhibited aggravation. Thirty-one patients with cerebral infarction were detected by cranial CT scans, among them 19 patients exhibited significantly reduced infarct size, and 12 patients who had self-care ability were found to restore the cerebral cortex activity. During the 1-year fol ow-up, 31 patients completed the fol ow-up, the remaining 6 cases were lost due to contact failure. Twenty-three cases achieved satisfactory long-term results, and returned to normal work and simple labor, two cases occurred contralateral cerebral infarction and became sicker. Decompressive craniectomy plus temporal muscle sticking therapy is an effective treatment for the majority of cerebral infarction.
4.Clinical observation of holmium laser lithotripsy under ureteroecopy for ureteral calculi: 162 cases report
Clinical Medicine of China 2011;27(8):859-861
Objective To investigate feasibility, efficacy and safety of holmium laser lithotripsy under ureteroscopy to treat ureteral calculi. Methods Clinical data of 162 patients with ureteral calculi treated by holmium laser lithotripsy under ureteroscopy in our hospital from June 2006 to October 2009 were reviewed retrospectively. Stone-broken rate,lithagogue rate and complication were observed. Results The overall rate of successful fragmentation for all levels of ureteral calculi in a single procedure achieved 96. 30% (156/162). The success rates of fragmentation for the upper and mid-lower segment of ureteral calculi was 86.11% (31/36)and 99.21% (125/126),respectively. In 156 patients, the postoperative follow-up of 2- 4 weeks revealed that the stone free rate was 98.08 % (153/156). The mean operative time was (36 ± 11 )mains ( ranged from 15 to 90) and hospital stay ranged from 1 to 10 days. Conclusion Holmium laser lithotripsy under ureteroscopy is feasible,high effective and safe for the treatment of ureteral calculi, especially for those with middle or lower levels ureteral calculi.
5.Thrombospondin-1 and taxol resistance
Journal of International Oncology 2010;37(5):341-344
Thrombospondin-1 is known as its anti-angjogenic and proapoptotic activities in oncogenesis. In current research, it has a intimate relationship with taxol resistance. Sensitivity of tumor cells to taxol will descend when the expression:of TSP1 is downregulated,and TSP1 downregulation is mediated by a new gene of taxol-resistance gene 1, the discovery provids a new trend to solve taxol resistance.
6.The study on hemodynamics changes of the regions surrounding hematoma in pafients with hypertensive cerebral hemorrhage
Chinese Journal of Postgraduates of Medicine 2010;33(2):21-24
Objective To the expression of cytokines assay in peripheral blood and hematoma fluid of hypertensive cerebral hemorrhage,and the hemodynamic changes in brain tissue around the hematoma by using perfusion computed tomography imaging(PCTT)and immune turbidimetric analysis and analyze its influence on prognosis.Methods Fifty-six cases of hypertensive intracerebral hemorrhage patients were inspected with conventional CT and PCTT,quantitative analysis of hematoma and the contralateral corresponding area around the cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time (MTT),comparing acute and subacute phase CBF,CBV,MTT change.Peripheral blood,hematoma fluid compiement C_3 and C_4 levels were detected.Results In 56 patients with acute phase ipsilateral CBF,CBV,MTT were(19.3 4±3.1)ml/(min·100 g),(1.4 4±0.4)ml/g,(16.5 4±3.1)s,respectively,and in eontralateral were(50.3 4±3.4)ml/(min·100 g),(2.4±1.1)ml/g,(4.8±2.6)s,the corresponding index difference between the two sides were statistically significant(P<0.05).Subaeute phase ipsilateral CBF,CBV,MTY were(29.7±2.1)ml/(min·100 g),(1.9±0.6)ml/g,(8.9±2.7)s,the in contralateral were (48.2±6.3)ml/(min·100g),(2.3±0.7)ml/g,(4.7±1.6)s,the corresponding index difference between the two sides were statistically significant(P<0.05).Subacute phase CBF,CBV,MTT compared with acute phase,the difference Wag statistically significant(P<0.05).Acute and subacute phase of complement C_3 and C_4 in peripheral blood and hematoma fluid content of the differences were statistically significant(P<0.05).Acute and subaeute phase of edema ratios were 0.9 and 0.4,the difference was statistically significant (P<0.05).Conclusions The cerebral blood flow and cerebral perfusion of the brain tissue amund hematoma after the cerebral hemorrhage are decreased.PCTI Can analyze the intracerebral hemodynamic changes of the brain tissue around hematoma after the cerebral hemorrhage,which is helpful to treat hypertensive cerebral hemorrhage and estimate its prognosis.
7.Analysis of related factors of superoxide dismutase level changes in elderly patients with coronary heart
International Journal of Laboratory Medicine 2015;(17):2497-2499
Objective To explore the related factors of plasma superoxide dismutase (SOD) levels in elderly patients with coro‐naryheartdisease.Methods 232elderlypatientswithcoronaryheartinthehospitalwereenrolledinthestudy,thepatientswhose plasma SOD≥129 U/mL were included as group A ,plasma SOD levels <129U /mL were divided into group B ,the difference ob‐served two groups were compared for each observation indicators .Results The two groups in age ,CRP ,TXB2 ,6‐Keto‐PGF1a were statistically significant different(P<0 .05) ,while in the gender composition ,ALT ,TG ,HDL ,LDL ,TC ,Cr ,Hcy was no significant difference(P>0 .05);the proportion of patients with stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis in the two groups were statistically significant different(P<0 .05);in the proportion of hypertension ,type 2 diabetes ,cancer was no statistical‐ly significant difference(P>0 .05);Non conditional Logistic regression results shown that the main factors that led to the decrease of SOD in elderly patients with coronary heart disease were age increase ,CRP increase ,TXB2 increase ,6‐Keto‐PGF1a decrease , stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis .Conclusion Old age ,elevated CRP ,elevated TXB2 ,decreased 6‐Keto‐PGF1a ,stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis are the factors leading to the decrease of plasma SOD in aged patients with coronary heart disease .
8.Effect of intracranial hematoma by drilling skull in treatment of hypertensive brain hemorrhage
Chinese Journal of Primary Medicine and Pharmacy 2009;16(12):2133-2134
Objective To analyze the clinical effect of intracranial hematoma by drilling skull in treatment with hypertensive brain hemorrhage.Methods 188 patients with hypertensive cerebral hemorrhage were classified into control group with 94 cases and traditional group with 94 cases.The control group were treated with conservative medicine and observation group were treated with intracranial hematoma by drilling skull.The clinical efficacy and defection score of nerves function were observed and compared between the two groups.Results The total effective rate in observation group was significantly higher than that in control group(P<0.05) while the death rate in observation group was significantly lower than that in control group (P<0.05),Compared with pre-treatment,after treatment 2 weeks and 4 weeks,the Barthel index in two groups were significantly increased(P<0.05).Moreover,after treatment 2 weeks and 4 weeks,the Barthel index in observation group was significantly higher than that in control group(P<0.05).Conclusion The intracranial hematoma by drilling skull can enhance effective rate,decrease death rate and improve the ADL ability.
9.Effect of IL-12 antibody on the survival of mouse heart graft
Chinese Journal of Organ Transplantation 2000;21(4):216-217
Objectives To establish the mouse heart transplantation model and observe the effect of anti-rejection of IL-12 antibody.Methods Twenty-five mice undergoing heterotopic heart graft were divided into 4 groups:isograft one(n=5),simple homograft one(n=6),γ-globulin treated one(n=6)and IL-12 antibody treated one(n=8).Results The survival time of cardiac graft in the groups was as follows:> 100 days in isograft group,7.3 days in simple homograft group,7.5 days in r-globulin treated group and 15.4 days in IL-12 antibody treated group.Conclusions A stable mouse heart transplantation modd was established.IL-12 antibody could significantly prolong the survival of mouse cardiac graft and antagonize rejection of organ transplantation.
10.Effect of Benazepril and Candesartan Combination for Treatment of Hypertension With Microalbuminuria
Chinese Circulation Journal 2005;0(04):-
Objective:To compare the effect between benazepril and candesartan combination and single medication in either one of them for treatment of hypertension-combined with microalbuminuria(MCA). Methods:A total of 95 patients were divided into three groups.Benazepril group(n=31),patients were treated with Benazepril 10~20 mg/day;Candesartan group(n=32),patients were treated with Candesartan 4~8 mg/day;and Combination group (n=32),patients were treated with benazepril 10 mg/day and candesartan 4 mg/day.The medication lasted for 8 weeks.Blood pressure(BP),plasma urinary albumin and creatinine ratio(A/C),endothelin-1(ET-1),nitrogen monoxide(NO)and potassium were examined and compared before and after the medication respectively. Results:The levels of BP,plasma A/C and ET-1 were decrease and NO was increased in all three groups(P0.05,respectively). Conclusion:Effect of benazepril and candesartan combination in patients with hypertension-combined microalbuminuria was better than single medication in either benazepril or candesartan.