1.Olfactory ensheathing cell transplantation repairs spinal cord injury
Chinese Journal of Tissue Engineering Research 2013;(31):5693-5698
BACKGROUND:Spinal cord injury can cause the motor, sensory and autonomic dysfunction below the damaged surface, so the repair of spinal cord injury has been the problem of neuroscience research. OBJECTIVE:To analyze the mechanism, experimental research and clinical application of olfactory ensheathing cel transplantation for the repair of spinal cord injury, and to investigate the effect of olfactory ensheathing cel transplantation on neurological function recovery. METHODS:The basic experimental and clinical researches on olfactory ensheathing cel transplantation for the repair of spinal cord injury were retrospectively analyzed, in order to analyze the relationship between the number and time of the survival cells and the structure and function of the damages spinal cord after olfactory ensheathing cel transplantation. The inclusion and exclusion criteria of the included clinical researches, and the sources, types and transplantation method of the cells used for transplantation were clearly defined, then the effective and objective evaluation criteria was established. RESUTLS AND CONCLUSION:The animal experiments of olfactory ensheathing cel transplantation for the repair of spinal cord injury have achieved satisfactory effects. The spinal cord function score and the sensory and motor function were significantly improved compared with those before transplantation (P<0.001). The successful animal experiment could provide basis for the clinical experiment and application. Parts of the clinical experiments were fol owed-up for 5 years. Because of a smal amount of the cases in the clinical research and the short fol ow-up period, the final recovery of large number of cases cannot judged yet, further observation and research were required. The great significance of the research result is to help to find a reasonable strategy that can make the olfactory ensheathing cells displayed repairing effect sufficiently.
2.Surgical therapy of senile gastric cancer complicated with portal hypertension
Chinese Journal of Geriatrics 2012;31(7):593-595
Objective To investigate the surgical treatment method for senile gastric cancer complicated with portal hypertension. Methods Retrospective analysis was used for 88 elderly patients who suffered from gastric cancer complicated with portal hypertension.Among the cases,35 cases were treated with standard radical resection,38 cases treated with cytoreductive surgery,9 cases with palliative operation,and 6 cases cured with jejunal fistula.Operation complications,death and mortality,the risk factors of postoperative complications were observed. Results For all the patients,the operation time was (170±33) min,and the intraoperative bleeding was (490±100) ml.In 35 patients (39.8%) occurred operation complications,among which the incidence of incision infection and anastomotic leakage was the highest, which accounted for 14.3% and 11.4%,respectively.In 5 years,69 patients were in death,the mortality rate was 78.4% which most resulted from liver failure (21.7%).Logistic regression analysis showed that age,tumor diameter,operation time and perioperation bleeding were the risk factors for death ( 95% CI:6.92-13.33,7.39-18.26,11.34 24.85,8.69-19.27). Conclusions The surgical approach for elderly gastric cancer patients complicated with portal hypertension should be chosen carefully,otherwise it will bring serious operation complications,and even endanger the lives of patients.
3.Innovation of logistics human resources management at public hospitals
Chinese Journal of Hospital Administration 2012;28(5):373-375
The author analyzed the present human resources at logistics departments of public hospitals,pointing out the way out for HR innovation,and probing into the practices of changing the management philosophy,in an effort of building a complete hospital logistics HR system,and developing an excellent hospital logistics team.
4.Clinical experience in the treatment of mycoplasma pneumonia using Azithromycin
Chinese Journal of Primary Medicine and Pharmacy 2011;18(22):3043-3044
Objective To study the clinical curative effect of Azithromycin in the treatment of mycoplasma pneumonia.Methods 24 cases of mycoplasma pneumonia hospitalization patients were selected and made full analysis of their medical records.Results 24 acute patients successfully cured through Azithromycin with good clinical curative effect,beginning with symptoms of fevering,coughing,wheezing,and small blisters in lungs,accompanied by external pulmonary manifestations such as diarrhea,myocardial injury and positive results of serum Mb-IgM test.Conclusion Azithromycin in treatment of mycoplasma pneumonia could quickly retum temperature,and reduc hospitalized time.
5.Investigation on the onset and development of the subjective acuity in normal infant
Journal of Chinese Physician 2011;02(z2):22-25
ObjectiveTo investigate the onset of the measurability and the evolution of the subjective acuity in normal infant.MethodsTwo hundred and sixty - four normal infants were measured using the crowded HOTV recognition symbol system for subjective acuity and the closed-circuit operant preferential looking system(COPL) controlled by computer for grating acuity.The onset of measurability and the evolution of the subjective acuity of the normal infant sample were recorded and analyzed.ResultsIn the study part of the infants with 24-month old began to recognize the subjective vision symbols ( 26.32% ).The measurability of subjective acuity of the infant group with 46 months old arrived to 100%.In the infants with 24-months old,the subjective acuity of the right eye was 4.86 ±0.05,left eye was 4.88 ± 0.08.In the infants with 46-months old the subjective acuity was 5.0 for both right and left eyes.According to Logistic regression analysis,the education background of the mother,and the instruction for infant showed the significant influencing factor.ConclusionThe study suggest that the crowded HOTV recognition symbol system controlled by computer provided a method to explore the onset of the subjective vision and the development of the infant.
6.Effect of IL-12 antibody on the survival of mouse heart graft
Chinese Journal of Organ Transplantation 2000;21(4):216-217
Objectives To establish the mouse heart transplantation model and observe the effect of anti-rejection of IL-12 antibody.Methods Twenty-five mice undergoing heterotopic heart graft were divided into 4 groups:isograft one(n=5),simple homograft one(n=6),γ-globulin treated one(n=6)and IL-12 antibody treated one(n=8).Results The survival time of cardiac graft in the groups was as follows:> 100 days in isograft group,7.3 days in simple homograft group,7.5 days in r-globulin treated group and 15.4 days in IL-12 antibody treated group.Conclusions A stable mouse heart transplantation modd was established.IL-12 antibody could significantly prolong the survival of mouse cardiac graft and antagonize rejection of organ transplantation.
7.Critical Discourse Analysis in Doctor-patient Discourse in Chinese Medical Clinic
Chinese Medical Ethics 2015;(1):8-12
Critical Discourse Analysis ( CDA) attempts to uncover the inequality in social reality and the way language presents power and ideology through the analysis of language features. Systemic functional linguistics ( SFL) focuses on the dialectical relationship between language and society and has been considered an important approach and theoretical basis to CDA. Doctors in Chinese medical clinic follow the Four Diagnostic Methods, within which the inquiry diagnosis strongly shows the fact that doctor and patient clash over the ideology and strug-gle for the power via language. The study carries out CDA on doctor-patient discourse in Chinese medical clinic within the theoretical framework of SFL from four aspects including nominalization, classification, transitivity and mood, which verifies that the language is the product of asymmetric power between doctor and patient. It is hoped that the paper would provide insight into CDA on doctor-patient discourse and would be of theoretical meaning.
8.Treatment of Child Diarrhea by Ginger-partitioned Moxibustion plus Tuina: A Report of 52 Cases
Journal of Acupuncture and Tuina Science 2003;1(6):20-21
Treated 52 cases of child diarrhea with ginger-partitioned moxibustion plus Tuina, after three treatments, all the patients are cured.
9.Decompressive craniectomy and temporal muscle sticking therapy of cerebral infarction:experience and problems
Chinese Journal of Tissue Engineering Research 2014;(11):1793-1798
BACKGROUND:A surgery can relieve the increased intracranial pressure, brain tissue edema, and brain stem compression in patients with massive cerebral infarction, and reduce the risk of serious complications, provide more time for medical treatment, and decrease the mortality and disability rate.
OBJECTIVE:To investigate the clinical value of decompressive craniectomy plus temporal muscle sticking therapy of cerebral infarction.
METHODS:A retrospective analysis was performed among the clinical data of 37 cerebral infarction patients, including 24 males and 13 females, they aged 10-55 years old. After decompressive craniectomy plus temporal muscle sticking therapy, the involved patients were fol owed up. The prognosis was evaluated according to the Glasgow Outcome Scale, as excel ent, good, moderate, none, and poor.
RESULTS AND CONCLUSION:At 6 months of fol ow-up, the total efficiency of surgical treatment in 37 patients was up to 89%, including excel ent in 5 cases (14%), good in 15 cases (41%), moderate in 13 cases (35%), none in 4 cases (11%). No cases exhibited aggravation. Thirty-one patients with cerebral infarction were detected by cranial CT scans, among them 19 patients exhibited significantly reduced infarct size, and 12 patients who had self-care ability were found to restore the cerebral cortex activity. During the 1-year fol ow-up, 31 patients completed the fol ow-up, the remaining 6 cases were lost due to contact failure. Twenty-three cases achieved satisfactory long-term results, and returned to normal work and simple labor, two cases occurred contralateral cerebral infarction and became sicker. Decompressive craniectomy plus temporal muscle sticking therapy is an effective treatment for the majority of cerebral infarction.
10.Analysis of related factors of superoxide dismutase level changes in elderly patients with coronary heart
International Journal of Laboratory Medicine 2015;(17):2497-2499
Objective To explore the related factors of plasma superoxide dismutase (SOD) levels in elderly patients with coro‐naryheartdisease.Methods 232elderlypatientswithcoronaryheartinthehospitalwereenrolledinthestudy,thepatientswhose plasma SOD≥129 U/mL were included as group A ,plasma SOD levels <129U /mL were divided into group B ,the difference ob‐served two groups were compared for each observation indicators .Results The two groups in age ,CRP ,TXB2 ,6‐Keto‐PGF1a were statistically significant different(P<0 .05) ,while in the gender composition ,ALT ,TG ,HDL ,LDL ,TC ,Cr ,Hcy was no significant difference(P>0 .05);the proportion of patients with stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis in the two groups were statistically significant different(P<0 .05);in the proportion of hypertension ,type 2 diabetes ,cancer was no statistical‐ly significant difference(P>0 .05);Non conditional Logistic regression results shown that the main factors that led to the decrease of SOD in elderly patients with coronary heart disease were age increase ,CRP increase ,TXB2 increase ,6‐Keto‐PGF1a decrease , stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis .Conclusion Old age ,elevated CRP ,elevated TXB2 ,decreased 6‐Keto‐PGF1a ,stroke ,bacterial pneumonia/acute exacerbation of chronic bronchitis are the factors leading to the decrease of plasma SOD in aged patients with coronary heart disease .