1.Observation of the Clinical Therapeutic Effect of Kanglaite(KLT)Combined with Chemotherapy on Late Cancers
China Pharmacy 1991;0(03):-
OBJECTIVE:To observe the clinical therapeutic effect of KLT combined with chemotherapy on late can?cers.METHODS:64patients with late cancers were assigned as observation group:receiving KLT+chemotherapy;47patients with late cancers were assigned as control group:receiving routine chemotherapy.RESULTS:In the observation group,the ef?fective rate was48.44%,body weight increase accounted for57.81%,KSP increased85.93%and relief from pain accounted for71.87%;In the control group:the effective rate was34.04%,body weight increase accounted for22.66%,KSD increased48.93%and relief from pain accounted for46.81%.The incidence of ARDs in observation group was obviouly lower than those in control group.CONCLUSION:KLT combined with chemotherapy can raise the therapeut effect on patients with late cancers and improve their life quality.
2.The present situation and future development of research on new algorithms of gait recognition with multi-angles.
Yibo LI ; Kun LI ; Xiaofei JI
Journal of Biomedical Engineering 2014;31(1):205-209
Gait recognition is a new technology in biometric recognition and medical treatment which has advantages such as long-distance and non-invasiveness. Depending on the differences between different people's walking pos tures, we can recognize individuals by characteristics extracted from the images of walking movement. A complete gait recognition process usually includes gait sequence acquisition, gait detection, feature extracting and recognition. In this paper, the commonly used methods of these four processes are introduced, and feature extraction methods are classified from different multi-angle views. And then the new algorithm of multi-view emerged in recent years is highlighted. In addition, this paper summarizes the existing difficulties of gait recognition, and looks into the future development trends of it.
Algorithms
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Biometry
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Gait
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Humans
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Image Interpretation, Computer-Assisted
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Walking
3.Clinical Observation of the Union of Fracture Promoted by Extraction of Bone-melon Injection
Hui LI ; Shunliang LIU ; Xiaofei YIN
Chinese Journal of Pharmacoepidemiology 2005;0(06):-
Objective:To explore the therapeutic effect of the extraction of bone-melon injection for the earlier fracture.Method:100 patients with early fracture were divided into two groups.50 cases in the treatment group used the extraction of the bone-melon injection and 50 cases in the controlled group used compound ossotide injections.Their curative effects were judged according to their healing time,level of relieving pain and functional recovery condition.Result: The patients in the treatment group healed earlier(P
4.Serum Epidermal Growth Factor Level Changes and Its Clinical Significance in Patients with Rheumatoid Arthritis
Xiaoxue ZHAO ; Xiaofei WANG ; Li JIANG
Journal of China Medical University 2010;(6):459-460
Objective To detect the serum levels of epidermal growth factor(EGF)in rheumatoid arthritis(RA)patients,and explore the possible role of EGF in RA.Methods The serum level of EGF was measured by enzyme-linked immunosorbent assay(ELISA)in 38 RA patients diagnosed according to dianostic criteria for RA by American Rheumatism Association and 20 healthy controls.Rheumatoid factor(RF),erythrocyte sedimentation rate(ESR)and C-creative protein(CRP)were also measured in these 38 RA patients.The relation beween the serum level changes of EGF and the corresponding clinical indexes in the two groups was statistically analyzed.Results Compared with the healthy individuals,the serum EGF levels of RA patients increased significantly(P 0.05).Compared with simple bone rarefaction patients,the serum levels of EGF increased significantly in the bone erosion patients(P 0.05).The serum levels of EGF in RA patients had no correlation with RF,ESR and CRP levels(P 0.05).Conclusion The evident increase of serum EGF level in RA patients,especially in bone erosion patients,suggests that EGF may partly play a role in the pathogenesis of RA.
5.Role of Fas, FasL and Caspase-3 in artesunate-induced apoptosis of human embryonic lung fibroblasts
Changming WANG ; Hongxiu LI ; Xiaofei ZHANG
Chinese Journal of Tissue Engineering Research 2011;15(20):3785-3788
BACKGROUND: Artesunate can relieve pulmonary fibrosis, but its mechanisms are rarely reported.OBJECTIVE: To explore the effect of artesunate on apoptosis of HFL-I cells and the role of Fas, FasL and Caspase-3 in the artesunate-mediated apoptosis of HFL-I cells. METHODS: Cell counting kit-8 (CCK-8) assay was used to determine the effects of artesunate at 1, 10, 100 mg/L on the growth of HFL-I cells in vitro. Apoptosis ratio was examined by flow cytometry (FCM). The mRNA level of Fas, FasL and Caspase-3, were assessed by reverse transcription-polymerase chain reaction (RT-PCR). RESULTS AND CONCLUSION: Artesunate had a significantly inhibitory effect on the proliferation of HFL-I cells in a dose-dependent manner in vitro. The apoptosis rate of HFL-I cells was significantly increased in the artesunate-treated group compared with the control group (P < 0.05 or P < 0.01). The mRNA levels of Fas, FasL and Caspase-3 were significantly higher in the artesunate-treated group than the control group (P < 0.05). The findings of this study demonstrate that artesunate can exert a marked anti-pulmonary fibrosis effect by up-regulating mRNA levels of Fas, FasL and Caspase-3, which can induce the growth inhibition and apoptosis in HFL-I cells.
6.Change of plasma substance P level in patients with ankylosing spondylitis
Li JIANG ; Xiaofei WANG ; Xiaotong SHI
Chinese Journal of Immunology 1999;0(12):-
Objective: TO study the change of substance P(SP) level in Plasma and its relationship with ankylosing spondylitis(AS).Method: Radioimmunoassay. Results: The author observed that the level of SP in Plasma of AS is singificantly higher than that of healthy controls. SP level in AS patients during active stage is higher than in those during inactive stage. Conclusion: Increased SP may play an importantrole in the pathogenesis Of AS.
7.Clinical application of lumbosacral somatosensory evoked potential to patients with lumbosacral disc herniation
Dongning WEI ; Xiaofei GENG ; Xiaojing LI
Medical Journal of Chinese People's Liberation Army 2001;0(12):-
Objective To evaluate the role of lumbosacral somatosensory evoked potential (LSSEP) examination in the diagnosis of lumbosacral disc herniation (LDH). Methods Somatosensory evoked potential (SEP) from posterior tibial nerve, L_4, L_5 and S_1 dermatomes SEP, and lumbosacral SEP was recorded in 54 patients with radiculopathy caused by LDH. Results The SEP from posterior tibial nerve was abnormal in 22 cases (40.74%). The SEP from L_5 and/or S_1 dermatome was abnormal in 47 cases (87.04%, P
8.Efficiency of differential diagnosis of myocardial injury markers in acute myocardial infarction(AMI)and angina pectoris by ROC analysis
Hua JING ; Dan LI ; Xiaofei WANG
Chinese Journal of Practical Internal Medicine 2006;0(19):-
CK.Efficiency of Myo decreases apparently after heart accident onset is more than 6 hours.Traditional marker,CK,CK-MB,AST,LDH and HBDH still have some efficiency in AMI diagnosis.
9.Modified method of cell culture for the tracheal tissue engineering in vitro
Sanming DENG ; Xiaofei LI ; ]ian WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(06):-
Objective To explore an easier method to get epithelial cell and fibroblast from a rabbit' s trachea for trachea tissue engineering in vitro. Methods Digest the epithelial cell and fibroblast by trypsin after co-culture for 6 days. Distinguish these two kinds of cells according to their different tolerances to trypsin and culture characteristics. The new method and the traditional method were compared by the proliferation of the cells with cell counting and MIT assay. Results The purity of the cells got with this new method is up to 100% . The cells proliferation is as same as that cultured by traditional methods. Conclusion With this method, one can get two kinds of different cells from the original in one time, it is easier to practice than the traditional.
10.Recombinant human bone morphogenetic protein-2 stimulation of cartilage regeneration in canine tracheal graft
Xiaofei LI ; Jian WANG ; Tao ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(02):-
Objective To induce regeneration of dog's tracheal cartilage by implanting the recombinant human bone morphogenetic protein-2 (rhBMP-2) into the tracheal graft in order to prevent the trachea from collapse. Methods RhBMP-2 with the atelopeptide type-1 collagen carrier was implanted around the cartilage ring of the autograft. New cartilage formed was detected with the histological analysis and immunohistochemical stain after 4 weeks. Six different concentrations of rhBMP-2 with collagen carrier were implanted around the cartilage ring in 6 auto transplantation groups respectively. The area of new cartilage regeneration was calculated in choosing the optimal dosage of rhBMP-2. Auto and allo tracheal transplantation were performed with rhBMP-2 implanted around the cartilage ring, the diameter of the grafts, histological analysis, and the area of the new cartilage regeneration were calculated. Results The addition of rhBMP-2 resulted in significantly greater amount of the new cartilage area (P