1.Ethical Discussion in the Diagnosis and Treatment of Oral Disease in Elderly Patients
Chinese Medical Ethics 1995;0(02):-
This article is to discuss the ethical principles in the diagnosis and treatment of oral disease in elderly patients.The patient-oriented concept should not be neglected.Doctors′ moral responsibility must be strengthened during examination,diagnosing and curing process.Medical skills should be well mastered and improved.Characteristic of senile patients should be attached to and right oral health education is obligatory for patients.
2.Management of Both War and Peace Time for Medical Equipment in Field Clinics
Chinese Medical Equipment Journal 1993;0(06):-
Objective To discuss the use management of both war and peace time for medical equipment in field clinics. Methods Medical equipment was sent to different departments which are personal management. Results The usage management can improve the capacity of using and maintaining of medical equipments. Conclusion The management method improves field medical treatment ability of field clinics and adapts the usage management of medical equipments in field clinics.
3.Advances in research on the mechanism of hypoxic pulmonary hypertension:role of 15-LO/15-HETE
Chinese Pharmacological Bulletin 1987;0(02):-
Hypoxic pulmonary hypertension(HPH) is a common disease featured by acute hypoxic pulmonary vasoconstriction(HPV) and chronic hypoxic pulmonary vascular remolding(HPVR) leading to the sustained increasing of pulmonary artery pressure.There are many mediators involved in the HPH but none can illustrate it successfully.Primary work has found 15-lipoxygenase(15-LO) and its catalyzed production 15-hydroxyeicosatetraenoic acid(15-HETE)(from arachidonic acid) are up-regulated in pulmonary vascular when exprosed to hypoxia.And it has been found 15-LO/15-HETE involved in many processes of both the HPV and HPVR,indicating 15-LO/15-HETE may be an important mediator of HPH.Advances research on 15-LO/15-HETE may illustrate the mechanism of HPH,and will give some message in looking for a potential clinical target of HPH.
4.Combined caudate lobectomy in Klatskin tumor: a systematic review
Chinese Journal of Hepatobiliary Surgery 2016;22(10):661-664
Objective To systematically review the risks and effectiveness of combined caudate lobectomy in Klatskin tumor.Methods A systematic literature search was conducted on PubMed,Embase,Cochrane Library,Scopus,CNKI databases and Chinese Bio Medical Literature (CBM).A systematic review and meta-analysis of the current literatures were conducted based on the PRISMA guideline.Odds ratios were calculated using the Mantel-Haenszel method.The primary outcome variables included safety,effectiveness of combined caudate lobectomy and its impact on long-term survival.Results Nine out of 312 articles were included.Results showed caudate lobectomy did not increase the incidence of postoperative complications (OR = 1.15;95 % CI 0.74-1.81;P > 0.05),but improved R0 resection rate (OR = 4.81;95 % CI 2.72 ~ 8.53;P < 0.01) and long-term survival in these patients (OR = 0.20;95% CI 0.11 ~ 0.39;P <0.01).Conclusion Combined caudate lobe resection is a safe and effective treatment for Klatskin tumor.
5.Difficulties and Countermeasures in Expanding Mobile Field Hospital in Earthquake Relief Mission
Chinese Medical Equipment Journal 2004;0(08):-
Objective To analyze and solve the difficulties in rapidly expanding the mobile field hospital in earthquake relief mission.Methods Aimed at the difficulties in the speed,advance men were sent out before the expansion.Then the personnel were regrouped in the proceeding of the expansion,and the vehicles entered the district according to the predefined area and order.Results The expanding speed was raised.Conclusion The scheme meets the requirements of the first aid in the mobile field hospital.
6.Hepatic Toxicity of Arsenic Trioxide on Rabbits with Hepatic Vx-2 Carcinoma by Transcatheter Arterial Chemoembolization
Mingyou ZHENG ; Xiaodong YU ; Tao WANG
Journal of Chinese Physician 2000;0(11):-
Objective To evaluate hepatic toxicity of arsenic trioxide(As 2O 3) on rabbits with hepatic Vx-2 carcinoma by transcatheter arterial chemoembolization (TACE), and its clinical signification. Methods New Zealand rabbits with hepatic Vx-2 carcinoma were managed with normal saline (experimental group 1), normal saline plus lipiodol (experimental group 2), and As 2O 3 plus lipiodol (experimental group 3) respectively by TACE once, whereas experimental group 4 was treated with As 2O 3 by transcatheter arterial infusion(TAI) for 7 days consecutively. The morphological changes of the tumor adjancent hepatic tissue were observed under light microscope and transmission electron microscope. The hepatic function of the rabbits was also determined. Results The hepatic cells of the rabbits in the experimental groups 2 and 3 were injuried in various degrees, but the injury extent was smaller than that in the experimental group 4 (P
7.Quick deployment flow for shelters of campaign-grade rapid medical support system
Xiaodong ZHENG ; Hongguang CHEN ; Shuxin LIU ; An ZHOU
Chinese Medical Equipment Journal 1993;0(06):-
This paper discusses issues involved in the deployment of the shelters of campaign-grade rapid medical support system in such aspects as entering of the vehicles,unloading of the shelters and grouping of the staffs. It suggests that the vehicles should rapidly move in at their positions and be butted bidirectional. As the system is deployed,such things should all be fixed as the position of the vehicles & equipments as well as the deployment motions and sequence. The system is positioned at hard surface,the shelters should be pushed towards the immobilized vehicles,but for the system located at soft surface,it is quite the contrary. With the above-mentioned measures implemented,the duration for shelters of campaign-grade rapid medical support system can be reduced largely.
8.Clinical effect of Gefitinib(Iressa)in 51 cases of none-small cell lung cancer(NSCLC)
Xiaodong XIE ; Zhendong ZHENG ; Shuxian QU
Chinese Journal of Practical Internal Medicine 2006;0(16):-
Objective To ascertain clinical experience and toxic reactions of treating NSCLC by Gefitinib(Iressa).Methods Clinical data of 51 NSCLC cases were collected and analyzed who were treated with Iressa from Mar.2004 to Mar.2006.Evaluations were made about curative effects,quality of life,mean survival time,time to progression and toxic reactions.Results Fifty-one patients were all followed up.Total mitigative rate of the focus was 29.4%,total control rate was 66.7%,and alleviative rate of clinical symptoms was 62.7%.The difference of KPS grades in 4 weeks was significant.Mean survival time of all the patients was 8.2 months.Time to progression was 6.1 months.Ⅲ~Ⅳ grades of toxic reaction were not found.Conclusion Gefitinib may obviously improve the clinical symptom and QOL of the NSCLC patients,and it has good tolerance to treat NSCLC.It is a kind of molecule-target medicine suited with Chinese.
9.Effect of olecranon osteotomy and triceps lobe flap pedicled combined with ossylated triol on humeral intercondylar fracture and its effect on prognosis of patients
Jinxin ZHENG ; Han JIANG ; Xiaodong LI
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):420-422
Objective To evaluate the effect of olecranon osteotomy and triceps pedicel approach combined with ossylated triol in the treatment of humeral intercondylar fracture and its effect on prognosis. Methods Ninety-two patients with humeral intercondylar fractures were selected as study subjects. The patients were randomly divided into two groups: the study group and the control group. The study group selected the olecranon osteotomy for treatment. The control group selected brachial Triceps tongue tongue approach for treatment. Results The excellent and good rate of the study group was significantly higher than that of the control group (P<0.05). The mean time of operation and the time of fracture healing were significantly higher than those of the control group (P<0.05), and The data of PLT, ESR, CRP and RF in the two groups were significantly lower than those in the control group (P<0.05) , and the data of inflammatory indexes in the study group were significantly decreased (P<0.05).Conclusion The treatment of humeral intercondylar fractures with olecranon osteotomy combined with calcitriol has a direct effect. It can be seen that this treatment has a high value in clinical orthopedic treatment.
10.Experimental study of BMP-2 derived peptide on osteogenic induction in BMSC in vitro
Zhixia DUAN ; Qixin ZHENG ; Xiaodong GUO
Orthopedic Journal of China 2006;0(21):-
[Objective]To investigate the capability of synthesis BMP-2-derived peptide on osteogenic induction in bone marrow stem cells(BMSEs),and to evaluate the osteoinductivity of BMP-2-derived peptide in vitro.[Method]After segregating and cultivating four weeks Wistar rats marrow stromal cells in induction group were induced by osteogenasis medium containing 200 gg/ml BMP-2-derived peptide,and in non-inductional group BMSCs were still culture with DMEM medium.Following continue culture for 2~4 weeks,cells film preparation,alkaline phosphatase activity and calcium deposition were measured.Type I collagen(CoM)and osteopontin(OPN)mRNA expression were measured using real-time fluorescent quantitative polymerase chain reaction(FQ-PCR)technique.The capability of synthesis BMP-2-derived peptide on osteogenic induction of BMSCs was investigated.[Result]After inductived with BMP-2-derived peptide.BMSCs cultured survived well greatly changed in cell morphology,and showed a biological and morphologie characteristics similar to those of osteoblasts.The lever of alkaline phosphatase activity and calcium deposition increased.Col-Ⅰand OPN mRNA were expressed at higher level.In non-inductional group no conspicuous osteogenic induction was shown.[Conclusion]BMP-2-derived peptide can induce BMSCs to differentiate into osteoblasts.It has the similar capacity of osteogenic induction as nature BMP-2,so BMP-2-derived peptide is an ideal cell agent for bone tissue engineering,and can be available widely.