1.Ethical Discussion in the Diagnosis and Treatment of Oral Disease in Elderly Patients
Chinese Medical Ethics 1995;0(02):-
This article is to discuss the ethical principles in the diagnosis and treatment of oral disease in elderly patients.The patient-oriented concept should not be neglected.Doctors′ moral responsibility must be strengthened during examination,diagnosing and curing process.Medical skills should be well mastered and improved.Characteristic of senile patients should be attached to and right oral health education is obligatory for patients.
2.Combined caudate lobectomy in Klatskin tumor: a systematic review
Chinese Journal of Hepatobiliary Surgery 2016;22(10):661-664
Objective To systematically review the risks and effectiveness of combined caudate lobectomy in Klatskin tumor.Methods A systematic literature search was conducted on PubMed,Embase,Cochrane Library,Scopus,CNKI databases and Chinese Bio Medical Literature (CBM).A systematic review and meta-analysis of the current literatures were conducted based on the PRISMA guideline.Odds ratios were calculated using the Mantel-Haenszel method.The primary outcome variables included safety,effectiveness of combined caudate lobectomy and its impact on long-term survival.Results Nine out of 312 articles were included.Results showed caudate lobectomy did not increase the incidence of postoperative complications (OR = 1.15;95 % CI 0.74-1.81;P > 0.05),but improved R0 resection rate (OR = 4.81;95 % CI 2.72 ~ 8.53;P < 0.01) and long-term survival in these patients (OR = 0.20;95% CI 0.11 ~ 0.39;P <0.01).Conclusion Combined caudate lobe resection is a safe and effective treatment for Klatskin tumor.
3.Advances in research on the mechanism of hypoxic pulmonary hypertension:role of 15-LO/15-HETE
Chinese Pharmacological Bulletin 1987;0(02):-
Hypoxic pulmonary hypertension(HPH) is a common disease featured by acute hypoxic pulmonary vasoconstriction(HPV) and chronic hypoxic pulmonary vascular remolding(HPVR) leading to the sustained increasing of pulmonary artery pressure.There are many mediators involved in the HPH but none can illustrate it successfully.Primary work has found 15-lipoxygenase(15-LO) and its catalyzed production 15-hydroxyeicosatetraenoic acid(15-HETE)(from arachidonic acid) are up-regulated in pulmonary vascular when exprosed to hypoxia.And it has been found 15-LO/15-HETE involved in many processes of both the HPV and HPVR,indicating 15-LO/15-HETE may be an important mediator of HPH.Advances research on 15-LO/15-HETE may illustrate the mechanism of HPH,and will give some message in looking for a potential clinical target of HPH.
4.Difficulties and Countermeasures in Expanding Mobile Field Hospital in Earthquake Relief Mission
Chinese Medical Equipment Journal 2004;0(08):-
Objective To analyze and solve the difficulties in rapidly expanding the mobile field hospital in earthquake relief mission.Methods Aimed at the difficulties in the speed,advance men were sent out before the expansion.Then the personnel were regrouped in the proceeding of the expansion,and the vehicles entered the district according to the predefined area and order.Results The expanding speed was raised.Conclusion The scheme meets the requirements of the first aid in the mobile field hospital.
5.Management of Both War and Peace Time for Medical Equipment in Field Clinics
Chinese Medical Equipment Journal 1993;0(06):-
Objective To discuss the use management of both war and peace time for medical equipment in field clinics. Methods Medical equipment was sent to different departments which are personal management. Results The usage management can improve the capacity of using and maintaining of medical equipments. Conclusion The management method improves field medical treatment ability of field clinics and adapts the usage management of medical equipments in field clinics.
6.An experimental study on time-dependent degradation of DNA in lymphocytes in the human bloodstain by single-cell gel electrophoresis
Jilong ZHENG ; Xiaona LI ; Xiaodong ZHANG
Chinese Journal of Forensic Medicine 1987;0(03):-
Objective To study time-dependent degradation of DNA in lymphocytes in the human bloodstain in order to estimate aging of bloodstain.Methods Lymphocytes were isolated from the human bloodstain placed under room temperature and were analyzed by single-cell gel electrophoresis(SCGE).The percentage of DNA-degraded lymphocytes were calculated in the cloodstain placed at different time intervals from 0 to 72h under fluorescent microscope connected with auto-analysis-image system.Results The percentage of DNA degraded lymphocytes was closely correlated with time lapse within 72h.A regression equation was formulated with R=0.9522(P
7.Discussion of mechanisms of rats with depression in Parkinson′s disease treated with Chaigan Jieyou decoction
Dandan MA ; Chunye ZHENG ; Xiaodong LUO
The Journal of Practical Medicine 2014;(23):3732-3735
Objective To build rat models and observe changes of behavior and monoamine of PDD. Methods The rats were injected with 6-OHDA and accepted CUMS for the establishment of PDD model , so as to assess its behavior changes and detect brain tissue monoamine contents by ELISA. Results Significant behavioral and monoamine abnormalities can be observed in model rats. Behavioral and monoamine improvement can be observed after treated with Chaigan Jieyou. Conclusion The PDD model can be established by 6-OHDA and CUMS. Chaigan Jieyou decoction may reach therapeutic purposes by increasing monoamine contents.
8.Effect of olecranon osteotomy and triceps lobe flap pedicled combined with ossylated triol on humeral intercondylar fracture and its effect on prognosis of patients
Jinxin ZHENG ; Han JIANG ; Xiaodong LI
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):420-422
Objective To evaluate the effect of olecranon osteotomy and triceps pedicel approach combined with ossylated triol in the treatment of humeral intercondylar fracture and its effect on prognosis. Methods Ninety-two patients with humeral intercondylar fractures were selected as study subjects. The patients were randomly divided into two groups: the study group and the control group. The study group selected the olecranon osteotomy for treatment. The control group selected brachial Triceps tongue tongue approach for treatment. Results The excellent and good rate of the study group was significantly higher than that of the control group (P<0.05). The mean time of operation and the time of fracture healing were significantly higher than those of the control group (P<0.05), and The data of PLT, ESR, CRP and RF in the two groups were significantly lower than those in the control group (P<0.05) , and the data of inflammatory indexes in the study group were significantly decreased (P<0.05).Conclusion The treatment of humeral intercondylar fractures with olecranon osteotomy combined with calcitriol has a direct effect. It can be seen that this treatment has a high value in clinical orthopedic treatment.
9.An analysis of diagnostic sources of 146 non-small-cell lung cancers
Xiaodong XIE ; Yanmei LIU ; Zhendong ZHENG
Chinese Journal of Practical Internal Medicine 2006;0(19):-
Objective To provide basis for treatment and prognosis judgement in order to further normalize diagnosis on non-small-cell lung cancer.Methods The diagnostic results of 146 cases with non-small-cell lung cancer were collected and analyzed.The patients received treatment in our department from Feb.2002 to Aug.2005.Results There were 123 cases of complete pathologic diagnosis,accounting for 84.2% of the total results;among other things there were 42 cases(28.8%)that obtained pathologic diagnosis through operation.There were respectively 31 cases(21.2%),18 cases(12.3%),15 cases(10.3%)and 11 cases(7.5%)that obtained diagnosis through phlegmy cytological examination,lymph node needle biopsy,hydrothorax cytology and bronchoscope among 104 cases without operation.There were 23 cases accounting for 15.7% through clinical diagnosis(on the basis of clinical physical sign and video examination without definite pathologic diagnosis).Conclusion To form a definite pathological diagnosis on tumors before treatment makes treatment be exact and helps to judge tumor development and prognosis.
10.Clinical effect of Gefitinib(Iressa)in 51 cases of none-small cell lung cancer(NSCLC)
Xiaodong XIE ; Zhendong ZHENG ; Shuxian QU
Chinese Journal of Practical Internal Medicine 2006;0(16):-
Objective To ascertain clinical experience and toxic reactions of treating NSCLC by Gefitinib(Iressa).Methods Clinical data of 51 NSCLC cases were collected and analyzed who were treated with Iressa from Mar.2004 to Mar.2006.Evaluations were made about curative effects,quality of life,mean survival time,time to progression and toxic reactions.Results Fifty-one patients were all followed up.Total mitigative rate of the focus was 29.4%,total control rate was 66.7%,and alleviative rate of clinical symptoms was 62.7%.The difference of KPS grades in 4 weeks was significant.Mean survival time of all the patients was 8.2 months.Time to progression was 6.1 months.Ⅲ~Ⅳ grades of toxic reaction were not found.Conclusion Gefitinib may obviously improve the clinical symptom and QOL of the NSCLC patients,and it has good tolerance to treat NSCLC.It is a kind of molecule-target medicine suited with Chinese.