In this model, carrageenin was used to induce pleurisy in rat. cAMP was measured with protein binding assay and cGMP with radioimmunoassay. The invest igation was designed to study the anti-exudative influence of the electric acupuncture in the process of inflammation with changes in cAMP, cGMP concentrations and their rel- ationship with the amount of exudete. The results showed that 12 to 24 hrs after inflammation, with the increase of exudate, cAMP concentration decreased and cGMP concentration increased. The exudate of the acupuncture group was obviosly less than in the control group (P

Objective: Our aim was to evaluate the biocompability of porcelain compounded with nanostructured material. Methods：The proliferation of the NIH3T3 cells were investigated using a tetrazolium-based colorimetric assay(MTT assay).Maceration extract of four tested materials were added into culture plate .The samples were tested with ultraviolet spectrophotometer in 490 wavelength at 1，3，5，7 days after the addition of extract. Morphology of these cells was also observed with phase-contrast microscope. Results： There was no obvious difference among three kinds of prosthetic materials in the optical absorbance and the cells growing in the extract showed normal morphology. Conclusion: The toxicity graduation of the porcelain compounded with nanostructured material is 0. This material has a good biocompability and can be used clinically.

Objective Measure the cytokines including hIFN-?、hIL-12 and hTNF-? which secreted by PBMC stimulated with recombinant BCG, and research how recombinant BCG influence the expression of cytokines and improve the immunologic response. Methods In the experiment, Recombinant hIFN-?-2b-BCG group and wild-type BCG group stimulate peripheral blood monocytes(PBMC) with different density in vitro, which is 0.1 OD and 0.01 OD (1 OD=2.7?107CFU). In third group, we put IFN-?-2b into wild-type BCG so that we can compare it with recombinant BCG. All these components foster with PBMC(4?106/ml), then collect the supernatant in 12 hours, 24 hours, 48hours, 72 hours, 5 day, 7day, and detect hIFN-?、hTNF-?, hIL-12 by an enzyme-linked immynosorbent assay(ELISA), compare the results. Results We can learn from the result, compared with the other groups, recombinant BCG can induce higher density cytokines than wild-type BCG’s and combination group’s(P

Objective To explore the treatment effect and prognosis of BiPAP non-invasive ventilator of sequential mechanical ventilation for the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with pulmonary encephalopathy,and to provide the basis for clinical therapy.Methods According to the digital table,62 AECOPD patients with pulmonary encephalopathy were selected and randomly divided into the two groups.And 30 cases in the control group received routine treatment,and 32 cases in the observation group received BiPAP non-invasive ventilator sequential ventilation.The partial pressure of oxygen (PaO2),partial pressure of carbon dioxide (PaCO2) and oxygen saturation (SaO2) before and after treatment,the changes of heart rate,respiratory rate and average arterial pressure of the two groups and the improvement time were observed.Results PaO2 and SaO2 of the two groups after treatment were higher than those before treatment (t =12.30,10.37,11.42,13.71,all P ＜0.05).PaO2 and SaO2 of the observation group after treatment were (77.14 ±4.16)mmHg and (90.37 ± 2.04) ％,which were higher than the control group after the treatment (72.96 ± 3.22) mmHg and (85.80 ± 1.96) ％(t =6.58,7.14,all P ＜ 0.05).PaCO2 of the two groups after treatment was lower than that before treatment (t =9.25,10.22,all P ＜ 0.05).PaCO2 of the observation group after treatment was (50.12 ± 2.86) mmHg,which was lower than that before treatment (54.27 ± 3.01) mmHg (t =6.29,P ＜ 0.05).The heart rate,respiratory rate and mean arterial pressure of the control group and the observation group after treatment were lower than before treatment (t =10.11,9.43,8.66,11.28,8.56,9.15,all P ＜0.05).The heart rate,respiratory rate and mean arterial pressure of the observation group after treatment were (76.52 ± 4.35) times/min,(20.35 ± 1.08) times/min and (83.26 ±3.07)mmHg,which were lower than those of the control group after treatment (t =6.44,5.82,6.70,all P ＜ 0.05).The blood gas improvement time,ventilation time and hospitalization time of the observation group were (4.06 ±1.17)d,(4.53 ±0.90) d and (16.18 ±2.20) d,which were lower than the control group (t =6.13,7.05,5.97,all P ＜ 0.05).Conclusion The BiPAP non-invasive ventilator sequential ventilation for the treatment of AECOPD with pulmonary encephalopathy has good treatment effect,which can improve the difficult ventilation of patients,avoid hypoxia and CO2 retention,shorten treatment time.

Objective To identify risk factors for anastomotic leakage after low anterior resection (LAR) in rectal cancer patients and study its impact on patients'long-term prognosis.Methods Chnical data were analyzed from 720 patients who underwent low anterior resection(LAR) for rectal cancer between 1996 and 2006.Results Anastomotic leakage after anterior resection occurred in 44 cases(6.1%).The median time of anastomotic leakage after operation was 5.6 days.Muhivariate analysis showed male patients.history of preoperative chemoradiation therapy,diabetes,cancer distance from anus less than 7 cm and hand-sewed anastomosis were independent risk factors predisposing anastomosis leakage (P<0.05).Tumor local recurrence rate was 13.6% in patients suffering from leakage and 5.9% for those without leakage (χ2= 4.116,P<0.05).The distant metastasis rates were 25.0 and 14.1 percent for the leakage and noaleakage groups,respectively(χ2=3.943,P<0.05).The survival rates were 56.8 and 72.5 percent in the leakage and nonleakage groups,respectively(χ2=4.979,P<0.05).Conclusion Sex,preoperative chemoradiation therapy,diabetes,cancer distance from anus less than 7 cm and hand-sewed anastomosis were found to be independent risk factors for anastomotic leakage after rectal cancer surgery.Anastomotic leakage was associated with poor prognosis.

As a kind of pesticide, fungicide and preservative, PCP had been used extensively in industry, agriculture and domesticity throughout the world. PCP contamination is generally associated with sediments or soil, it can also concentrate in organism. Regarding the character of high toxicity, long persistence and difficult to degrade, PCP has become a kind of conspicuous environmental pollutant because of widely use and inappropriate disposal. In the contaminated area, PCP can be detected in the water, soil and the body of organisms. PCP can affect human health through directly exposure or through food chain. The absorbed PCP can be stored in liver, kidney and fat,it can also increase the incidence rate of tumork, disturb the endocrine system, affect immune function,inhibit reproduction and development. PCP not only has a direct impairment on human body but also shows a potential impact in genetics.

Objective To evaluate the practical value of preventive jejunum stoma for enteral nutrition in abdominal operation.Method Retrospectively analyzed 43 cases (from July,1995 to July, 2001) of patients under went performed with abdominal operation and preventive jejunum stoma, and compared their practical value in different diseases.Results The frequency of practical usage of jejunum stoma in acute severe pancreatitis was the highest (87%,13/15),while it was less in the patients group of upper digestive tract tumor and biliary or portal venous hypertension(41.67% and 45.45% respectively,P0.05 when compared with pancreatitis group.Conclusions Preventive jejunum stoma for enteral nutrition in abdominal operation must take into account three factors (disease, patient, and surgeon).Viewing from the diseases,the acute severe pancreatitis should be considered,patients with combined wound must be considered conditionally, patients with upper digestive tract tumor or biliary operation together with bile exo-drainage may take into account according to different situation,patients with portal venous hypertension should not be advocated.

A method which combines empirical mode decomposition with wavelet transform is employed to remove breathing baseline draft from pulse wave signal. First of all, this method decomposes pulse wave signal into several intrinsic mode functions and judges the intrinsic mode function which contains the information of breathing baseline draft. And then wavelet transform is used to decompose these intrinsic mode functions, and the detail coefficients representing breathing baseline draft are set into zero. At last, the signal is rebuilt. This can realize removing breathing baseline draft. A self-developed measurement device was used to obtain the pulse wave signal for validating, and AC-DC modulation ratio value was adopted to evaluate the effect. The results showed that this method could effectively remove breathing baseline draft from pulse wave signal.
Algorithms ; Oximetry ; instrumentation ; methods ; Respiration

[Summary] Four women with uterus submucosal myoma without sexual experience were treated with hysteroscopic surgery from January 2008 to January 2015.There were 2 cases of 0 type myoma, 1 case of Ⅱtype myoma, and 1 case of multiple myomas with 0 type,Ⅰtype, andⅡtype, respectively.The operation was performed by using the plasma bipolar hysteroscopic resectoscope (sheath diameter , 8 mm) .All the operations were successfully completed with myoma resected in one time .The hymens were undamaged .The patients were followed up for 6, 4, 3, and 1 year, finding no recurrence .One patient naturally conceived after 6 years postoperatively and gave birth to a healthy baby .