To understand the current situation of public health service system by using diect network report,system report and questionaire surey, so as to provide reasomable suggestion for the existing problems.

Objective: To obtain the data of the surfaces of stand ar d posterior teeth crowns with an improved measurement system, so as to lay the f oundation for fabrication of dental prosthesis with computer aided design and la ser solid forming technology. Methods: Standard posterior teeth models were measured with a numerical controlled miller and a new data col lection system by cutting and scanning layer by layer, and the 3 dimension (3 D) shape of the models was reconstructed by image processing with a special soft ware. Results: Data of image profile and 3D shape of sixte en posterior teeth crowns were obtained. Precise configuration was acquired.Conclusion: Data of image profile can be easily and clearly ob tained by the improved measurement system with no measuring blind spot.

Objective: To reconstruct 3D shape of upper edentulous jaw f or the design of a digital model of palatal metal plate of upper complete dentur e. Methods: Standard edentulous jaw models were measured with a numerical controlled miller and a new data collection system by cutting and sca nning layer-by-layer, the 3D shape of the models was reconstructed by image pr ocessing with special software. Based on these data, a palatal metal plate of u pper complete denture was designed by using SURFACER softerware.Results: Data of upper edentulous jaw models and a palatal metal plate of upper c omplete denture were obtained.The error between basal surface of the plate base and uper endentulous jaw was 0.0245 ?0.0267 mm. Conclusion:E dentulous jaw can be reconstructed by three-dimensional measurement, the design ed palatal metal plate of upper complete denture will be helpful to the further Laser Solid Forming.

Objective:To investigate the microstructure and mechanical property of titanium parts made by laser solid forming technology. Methods: Titanium parts were made by laser solid forming technology; microstructure and elements were observed by SEM and spectrum analysis. The mechanical property of laser formed titanium and TA2 titanium were measured by Omnipotent testing machine. Results: The microstructure of titanium parts fabricated by laser rapid forming has columnar crystals with regular and epitaxial growth. The inner structure is dense and acicular structure distributed uniform at all field with width about 3-4 ?m; No obvious impurity elements were observed; the tensile-strength and yield strength of titanium parts is obviously superior to the standard of TA2. Conclusion: The microstructure of titanium parts made by laser solid forming can be obviously improved and mechanics performance was greatly improved. Those titanium parts may be used for dental restoration.

OBJECTIVE To evaluate the methods of improving the air quality in the outpatient departmant area.METHODS The amount of outpatients in different time periods in the morning were calculated in the specialist consulting area;the bacteria in the air collected from the clinic room were collected and cultured in general nutrition agar medium and compared the efficacy for the improvement of air quality between the new and the old methods.RESULTS The air quality of the specialist consulting area was improved significantly through the ventilation and cleaning-floors depending on the amount of outpatients(P

OBJECTIVE:To observe clinical efficacy of epinephrine combined with vasopressin and naloxone for cardiopulmonary resuscitation(CPR)and to investigate its mechanism. METHODS:64 patients with sudden cardiac and respiratory arrest were randomly divided into control group(epinephrine group),treatment group Ⅰ(epinephrine+vasopressin group)and treatment group Ⅱ(vasopressin+epinephrine+naloxone group). Spontaneous circulation,breathing recovery time,restoration of spontaneous circulation and respiration rate,24 h survival rate and discharge survival rate were observed and compared among different groups. RESULTS:As compared with control group,spontaneous circulation,breathing recovery time 24 h survival rate and discharge survival rate in treatment group Ⅰ and Ⅱwere increased significantly(P

AIM: To investigate the effects of proteasome inhibitor Z-LLL-CHO(MG132) on human osteosarcoma cell line MG-63 and its possibly mechanism.METHODS: After treated with different concentration of MG132,the morphological change,ultrastructral morphology,cell viability,cell apoptosis,gene transcription and protein expression in MG-63 cells were accessed by fluorescence microscope,electron microscope,MTT assay,agrose gel electrophoresis,FCM,RT-PCR and Western blotting.RESULTS: Proteasome inhibitor MG132 was an effective inducer of apoptosis in human osteosarcoma MG-63 cells.Not only apoptotic changes,but also cell arrest at G2-M-phase,the accumulation of p27kip1,the accumulation of activated caspase-8 and increased ratio of Bax∶Bcl-2 were observed.However,to normal human diploid fibroblast cells,MG132 did not show apoptosis-inducing effect.CONCLUSION: Apoptosis induced by MG132 may be caspase-8,p27kip1and bcl-2-related.

Objective To investigate effects of diabetes mellitus (DM) on pharmacokinetics (PK) of cephradine (CED).Methods DM model was induced by iv.alloxan 60 mg·kg-1.A reversed phase HPLC internal standard method was developed for measurement of CED plasma concentration.After blood collection,rats were sacrificed to collect kidneys for calculating kidney index(KW/BW).DM and normal control (CTL) rats were randomly assigned to receive iv.or ig.CED at a dose of 180 or 90 mg·kg-1.The 3p97 program was used to calculate PK parameters.Results The developed HPLC method was validated to have high specificity,precision,recovery and good storage stability,and met requirements for PK study of CED.The CED in rats of both DM and CTL groups showed the iv.two-compartment PK and ig.one-compartment PK and followed the first-order kinetics.Following iv.dosing,a remarkably decreased t1/2β and MRT,increased CLt were evident in DM group as compared with CTL group (P ＜ 0.05).After ig dosing,a significant decrease in t1/2k and t a remarkable increase in CLt and Cm=were observed for DM group as compared with CTL group (P ＜ 0.05).The DM rats showed a trend of decreased t1/2ka vs CTL rats.There was no significant difference in the oral bioavailability between the two groups (P ＞ 0.05).KW and KW/BW in DM group were increased remarkably compared with CTL group (P ＜ 0.05).Conclusion The DM vs CTL results in faster absorption and elimination of CED in rats,but does not have significantly affect in oral bioavailability.The compensatory hypertrophy and hyperfunction of early-stage diabetic kidneys may constitute one of causes of quick elimination of CED in rats with DM.

Spontaneous intracerebral hemorrhage is the most deadly type of stroke.Its 30-day mortality rate is nearly 40％.More than 30％ of patients with spontaneous intracerebral hemorrhage will have hematoma growth,which lead to poor outcomes.In addition to the classic predictors,some inaging signs also have important implications for identifying hematoma growth,such as swirl sign,blend sign,and black hole sign on nonenhanced CT scans,extravasation sign on contrast-enhanced CT scans,spot sign on CT angiography,leak sign revealed by the modified imaging method,as well as the spot sign on CT peffusion imaging.

In order to understand the cost of cancer in rural area, to evaluate the cost burden, the project content and treatment status. Typical sampling and random sampling survey are combined to investigate and account major expenditure and economic loss of cancer treatment and related items, analyzes its rationality and scientific, provide references for improving the level of cancer prevention and treatment.