1.Hospital Infection Administration in Chinese Level Ⅱ Hospital of UN Peacekeeping Army in Lebanon:Current Situations and Measures
Chinese Journal of Nosocomiology 2009;0(20):-
OBJECTIVE To improve efficiency of hospital infection administration and take strict precautions against medical malpractice in Chinese level Ⅱ hospital of UN Peacekeeping Army in Lebanon.METHODS The current situations of its hospital infection administration were enumerated,compared and analyzed,and corresponding measures of administration were suggested.RESULTS Under the influence of characters of medical missions during peacekeeping,the hospital infection administration presented the problems that patients and disease spectra were diversified,the rate of hospital infection was influenced by peacekeeping mission,the positive rate of HIV was high,medical workers protection awareness was lagged behind,and the disposition of hospital was illegitimate;many measures should be taken to enhance the administration level.CONCLUSIONS In order to well develop the hospital infection administration in Chinese level Ⅱ hospital of UN Peacekeeping Army in Lebanon,we should reform and improve the system of hospital infection administration,and establish an effective and systematic prevention system of hospital infection.
2.The design of bionic left ventricular auxiliary pump.
Henglin JIN ; Xiaobing HU ; Lei DU
Chinese Journal of Medical Instrumentation 2015;39(1):29-32
This paper reports a novel design of bionic left ventricular auxiliary pump, and the characteristic is that elastic diaphragm of pump driven by hydraulic, having smooth, reliable blood supply, can prevent blood clots, can use the flow sensor, pressure sensor detection showing the blood pressure and blood volume at the inlet and outlet of the pump. The pump can go with heart rate synchronization or asynchronous auxiliary by the R wave of human body's ECG. The design goal is realization of bionic throb. Through the animal experiment, the blood pressure waveforms are close to expectations, stable flow can stroke according to the set value, which prove that the pump can meet the requirement for heart disease patients for bionic left ventricular assistant.
Animals
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Blood Pressure
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Heart Rate
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Heart Ventricles
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Heart-Assist Devices
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Humans
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Prosthesis Design
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Ventricular Function, Left
3.Concomitant chemoradiotherapy for prevention of recurrence and metastasis in the surgical treatment of salivary adenoid cystic carcinoma
Moyi SUN ; Xiaoguang HU ; Xiaobing CHENG
Journal of Practical Stomatology 1996;0(02):-
Objective: To evaluate the effect of concomitant chemoradiotherapy for the prevention of recurrence and metastasis of postoperative salivary adenoid cystic carcinoma(SACC).Methods: 14 cases of salivary adenoid cystic carcinoma after operation were treated with concomitant chemoradiotherapy. Regular radiotherapy of 60 Gy and chemotherapy with hydroxycamptothecin (HCPT) at 10 mg/m 2 , 3 times a week, were administered. HCPT was given in 1st, 2nd, 4th and 5th week. Recurrence and metastasis of SACC after operation were observed using CT, MRI, ultrasonography and X ray. Results: After 3~17 months' follow up, relapse free survival was 100%. No recurrence and metastasis of SACC after operation were found. Adverse reactions of the chemotherapy were nausea, vomiting and leukopenia. After suspended in a short time and using ondansetron and /or G CSF the chemotherapy of HCPT was continued and completed. Conclusion: concomitant chemoradiotherapy of HCPT and radiotherapy can prevent recurrence and metastasis of SACC after operation. The efficacy of long term needs further observation.
4.The inactivation of duck hepatitis virus B in blood cell suspenion induced by specific photosensitizer
Hongyan XIONG ; Huisun CHEN ; Xiaobing HU
Chinese Journal of Blood Transfusion 1988;0(03):-
Objective:To study the specific photochemical effects of a newly designed target photosensitizer. Methods Based on the technique of antisense nucleic acid and the principle of photochemical reaction effects,a specific sensitizer,TFO P has been designed and synthesized.When in coordination with long wave ultraviolet ray(UVA) ,this decorated complex (TFO P) was added into the blood cell suspension to inactivate the contaminating virus( duck hepatitis virus B,DHBV).The efficacy of specific binding to DHBV DNA and viral inactivation by TFO P was detected by gel shift blot assay and infection of primary culture of duck hepatocyte.Results The designed TFO P could specifically bind to different DHBV DNA line sample and present different linking level.With a TFO P concentration of 0.1 nmol/ml and UVA intensity of 1800 ?W/cm 2,the DHBV in blood cell suspension could be reduced by 1.90~5.40 logs.Conclcusion The photochemical effects of TFO P could significant inactivate DHBV in blood.
5.Photochemical effect of MB on the inactivation of E. coli in blood and biologic functions of blood cells
Xiaobing HU ; Hongyan XIONG ; Jianyong SONG ; Sixiong WANG ;
Journal of Third Military Medical University 2003;0(18):-
Objective To observe the photochemical effect of methylene blue (MB) on the inactivation of E. coli in blood and on biological functions of blood cells. Methods The blood was treated with 15 ?mol/L MB, 40 000 Lux halogen lamp irradiation and 0.35 mmol/l rutin for 10~40 min. The photochemical effect of MB on the inactivation of E.coli in blood was observed. The changes of biologic functions of blood cells were measured by means of RBC membrane binding to poly L lysine, reaction promoted by ATP enzyme and neutrophil phagocytosis tests. Results After treatment for 40 min, the E.coli count in blood decreased by 5 log units. The value of T/E of MB and irradiation of halogen lamp was higher than 1. No obvious changes of the morphology of blood cell were found. The negative electrical charges on membrane of RBC decreased by 11.23%~25.49%. After treatment of the blood for 20~30 min, the activity of Na + K +ATP enzyme of RBC membrane increased by 7.60%~20.07%. When the blood had been treated for 10~20 min, the positive rate of neutrophil phagocytosis enhanced by 9.00%. Conclusion MB photochemical treatment can effectively inactivate E. coli in blood. Under morphology specific condition of effectively inactivated blood bacteria, the shapes and functions of blood cells are not altered, but the RBC adhesion may increase by about 11.23%~25.49%.
6.Management of condylar fractures by using open-mouth jaw plate in children
Cheng YANG ; Moyi SUN ; Yaowu YANG ; Xiaoguang Hu ; Xiaobing CHENG
Journal of Practical Stomatology 2000;0(06):-
Objective: To investigate the effect of open-mouth jaw plate in the treatment of condylar fracture in children. Method: Open-mouth plates in the height of 2~3 cm were respectively made in op e n-mouth position for 12 children aged 3~6 years old with condylar fractures an d used by the children with the help of doctors or parents for 3~6 months.Follo w -up was carried out by clinical observation and X-ray radiograph.Re sults: Satisfactory results were obtained in all the patients examine d by clinical observation and X-ray radiograph. Conclusion: The method of open-mouth plate is effective in the treatment of condylar f racture in children.
7.Application of prone-straddle position for transvaginal hysteromyomectomy in the posterior wall of the uterus
Xiaobing HE ; Xinjuan MA ; Wenxiao HU ; Yong MAO ; Zhenxiang JIA
Journal of Regional Anatomy and Operative Surgery 2015;(5):497-498,499
Objective To discuss the safety and advantages of prone-straddle position applied in transvaginal hysteromyomectomy of the posterior wall of the uterus. Methods The clinical data of patients who were admitted into our hospital from March 2013 to Janaury 2015 and received transvaginal hysteromyomectomy were retrospectively analyzed. They were divided into group A ( prone-straddle position, 30 cases) and group B (traditional lithotomy position,24 cases). The exposure of operative field, convenience of operation, time of the placement, time of operation, patient satisfaction, as well as patients’ heart rate, blood pressure, and oxyhemoglobin saturation were observed and ana-lyzed. Results Compared with the lithotomy position, there were significant differences in the time of the placement and the time of opera-tion in the patients treated by prone-straddle position. The patients with prone-straddle position cooperated well, and there was no obvious discomfort. Their vital signs were stable during the operation. The operative field during prone-straddle position exposed better and it was more convenient which make the operation became easier for both the operators and nurses. Conclusion Prone-straddle position applied in transvaginal hysteromyomectomy of the posterior wall of the uterus is safe and practicable, and it is valuable for clinical application.
8.Diagnosis value of MRI to cerebellopontine angle tumor: analysis of 96 cases
Wenzhong HU ; Xianwei ZENG ; Honglin LIU ; Xiaobing CHEN ; Guoqing DUAN
Clinical Medicine of China 2011;27(7):688-691
Objective To improve the preoperative diagnosis accuracy of cerebellopontine angle tumors through analyzing MRI findings. Methods Ninety-six cases with cerebellopontine angle tumors, confirmed by pathology and surgery, were collected and underwent MRI scan plus enhanced MRI. Among the 96 capes, we observed acoustic neurinoma in 55 cases, meningioma in 20 cases, cholesteatoma in 9 cases, trigeminal neuroma in 7 cases,cavernous hemangioma in 3 cases,arachnoid cyst in 2 cases. The MRI characteristics of all cases were analyzed retrospectively. Results The chief type of tumor happened in the cerebellopontine angle zone was acoustic neurinoma,followed in order by meningioma,cholesteatoma,trigeminal neuroma,cavernous hemangioma and arachnoid cyst. The accuracy of preoperative localization and qualitative diagnosis were 100% and 94.7%respectively.Conclusion MRI has a high value in the diagnosis and differential diagnosis of cerebellopontine angle tumors,which can be used as a preferred preoperative examination method in cerebellopontine angle tumors.
9.The application of HA330-Ⅱ microporous resin plasma adsorption in the treatment of chronic severe hepatitis
Xiaobing HU ; Hongbo GAO ; Minger LIAO ; Minru HE
Chinese Journal of Primary Medicine and Pharmacy 2008;15(3):380-382
Objective The aim of the study is to discuss the application value of HA330-Ⅱ microporous resin plasma adsorption in liver support and the treatment of complications of chronic severe hepatitis.Methods The treatment group has 41 patients of chronic severe hepatitis B,which were treated for 3 times by HA330-Ⅱ microporous resin plasma adsorption.We compared the improvement of symptom,the fadeamay and rebound of icterus,the change of hepatic encepllalOpathy and brain oedema,the change of blood routine test,blood ammonia level,blood-gas analyzing result,cruor index,inflammatory factors(IL-1b,IL-6,IL-8,TNF-α,etc.),side effects,etc.The control group has 37 patients of the same type.Results HA330-Ⅱ microporous resin plasma adsorptioin is partly effective for the improvement of symptom,improvernent rate 43.9%,and without new discomfort due to the treatment. It obtains some extent fadeaway of icterus which has a low rebound,reduce TBiL(17.83±3.65)% and there be no statistics difference of rebound.It lowers the blood ammonia level and improves the hepatic encephalopathy and brain oedema.It absorbs cytokine IL-8.Atthough it has some extent effect to albunfin,blood paltelet,haemoglobin.Conclusion HA330-Ⅱ microporous resin plasma adsorption has good application value in the treatment of chronic severe hepatitis B.It is a new treatment choice of severe hepatitis.
10.Application of discussional teaching to medical education
Xiaotian HU ; Yanchun SUN ; Xiaokang YAO ; Xiaobing ZHANG ; Li LV
Chinese Journal of Medical Education Research 2011;10(3):294-295
In medical education,the application of discussion of teaching reform can enhance medical students'interest in learning,stimulate their innovative thinking,develop their clinical thinking and critical thinking.improve their psychological quality and language skills and improve knowledge and comprehensive quality of teachers as well.