1.Risk factors analysis and treatment of postoperative complications after laparoscopic radical gastrectomy
China Journal of Endoscopy 2017;23(2):34-36
Objective To analyze the risk factors and treatment methods of postoperative complications after laparoscopic radical gastrectomy.Methods Clinical data of 117 patients with gastric cancer before and after operation were evaluated, and the possible risk factors of postoperative complications were evaluated.Results Laparoscopic BillrothⅡ gastric cancer radical postoperative complications included incision infection, infection of the lung or pleural or peritoneal infection, obstructed jejunum anastomotic ifstula, incidence of 35.04% (41/117), operation method, operation time, the tube indwelling time, postoperative life habits and postoperative complications.Conclusion Laparoscopic BillrothⅡ gastric cancer radical postoperative complications by a variety of reasons is due to a combination, except for patients with quality and disease factors, 6 risk factors are as follows: the whole stomach resection, surgery time 4 h, hemorrhage 800 ml, gastric tube indwelling time of 3d, long-term smoking, and abdominothoracic incision, more attention should be paid to the perioperative treatment. Surgery time 4 h, gastric tube indwelling time of 3 d, long-term smoking, and abdominothoracic incision are the main risk factors.
2.Correlation Between Wnt5a Expression and Vasculogenic Mimicry in Prostate Cancer Tissues
Bide LIU ; Xun LI ; Shuheng WANG ; Hongliang JIA ; Xiaoan ZHANG ; Jiuzhi LI
Cancer Research on Prevention and Treatment 2024;51(1):43-48
Objective To investigate the correlation of Wnt5a expression and vasculogenic mimicry (VM) in prostate cancer tissues, and analyze their relationships with cancer stem cells (CSCs) characteristics and epithelial–mesenchymal transition (EMT). Methods Immunohistochemistry was conducted to detect the expression of Wnt5a in 50 prostate cancer tissues and 50 benign prostatic hyperplasia tissues. The expression levels of CD133, vimentin, and E-cadherin were detected in the prostate cancer tissues, and CD34/PAS double staining was used to detect VM structures. We analyzed the difference in Wnt5a level between prostate cancer and benign prostatic hyperplasia tissues, the clinical significance of Wnt5a and VM, the relationship of Wnt5a expression and VM, and the relationships of Wnt5a expression and VM with CD133, Vimentin, E-cadherin. Results The expression of Wnt5a was significantly higher in prostate cancer tissues than in benign prostatic hyperplasia (