Objective To investigate the value of 64 row CT low dose scanning technique in thyroid enhancement scanning.Methods From Jan.2016 to Dec.2017,152 patients with thyroid occupying lesions were studied in our hospital.All the patients underwent multislice spiral CT enhanced scan and pathological examination.The patients were divided into four groups according to the different current and voltage of multislice spiral CT.The significance of multi slice spiral CT scanning in the 4 groups was compared.Results There were no significant differences (U=0.1825,P=0.351 8＞0.05)among the four groups of multi-slice spiral CT in the detection rate of nodular thyroid lesions (96.21％,94.38％,85.71％,87.50％) or the detection rate of diffuse thyroid lesions (77.78％,83.33％,80.00％,83.33％).There were significant differences in CTDIvol,DLP and ED among the four groups (P＜0.05),and the radiation dose of group D was lower than that of group A and C.There were significant differences in thyroid CT value,background noise and background signal among the four groups (P＜0.05).The thyroid CT value,background noise and background signal in group D were higher than those in group A,B and C (P＜0.05).There was no significant difference in SNR and CNR among the four groups (P＞0.05).There was no significant difference in subjective evaluation of CT scan images between the four groups (P＞0.05).Conclusion The multislice spiral CT low-dose scanning technique used in thyroid enhanced scan can obtain satisfying scanning images,which is not only beneficial to the quality of the images,but also can improve the accuracy of the diagnosis and reduce the ionizing radiation damage to the patients.