1.Distinguishing Plastrons of Tortoise's Shell and Plastron (Chinemys reevesii )and Its Adulterat of Yanbanzhaogui (Morenia ocellata )
Ran AN ; Xiaofan GU ; Jielin WANG
Chinese Traditional and Herbal Drugs 1994;0(06):-
Plastrous of Chinemys reevesii (Gray) and Morenia ocellata (Dum.et Bid) are compared and identified by characte rization, TLC and UV spectroscopy.The method is simple and reliable.
2.Zishen Tiaochong therapy and promoting vasculogenesis in corpus luteum
Ling WANG ; Yanming SUN ; Xiaofan LIU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(07):-
Zishen Tiaochong therapy can improve the function of corpus luteum.The function of corpus luteum has close correlation with vasculogenesis in which the bone marrow-derived endothelial progenitor cells(EPCs)were involved.This implies the Zishen Tiaochong therapy may be correlative to vasculogenesis in corpus luteum via mobilizing bone marrow-derived EPCs.In this paper,based on the TCM theory of 'kidney(Shen) storing essence,producing bone marrow,controlling reproduction',we review the topic of Zishen Tiaochong therapy perfects the function of corpus luteum combined the new mechanisms of research advances in vasculogenesis.The possible mechanisms of promoting vasculogenesis in corpus luteum by Zishen Tiaochong therapy were discussed and analyzed.
3.Analysis on Problems in Circulation of Traditional Chinese Medicinal Materials from the Perspective of Economics
Xiaofan WANG ; Ying LIU ; Qi LI
Chinese Journal of Information on Traditional Chinese Medicine 2016;23(4):1-4
Circulation of traditional Chinese medicinal materials, as the vital part of the TCM industrial chain, plays an important role in the connection of agriculture link and industry link of traditional Chinese medicinal materials, which has influence on the healthy development of the whole TCM industrial chain. Because circulation activities mainly include exchange and storage activities instead of manufacturing real products, they are much more difficult to be managed compared with producing activity. This would lead to problems in circulation of traditional Chinese medicinal materials, and impose negative effects on TCM industry. Based on scale economy theory, information asymmetry theory and cobweb model theory, this article analyzed the problems in circulation of traditional Chinese medicinal materials, discussed the deep reasons behind these problems, and proposed relevant suggestions for optimization.
4.Effect of Drogon’s Blood on the Expression of GSK-3? in Liver and Muscle of Mice with DM
Chun LIU ; Xiaofan FENG ; Yanjie WANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(07):-
Objective To study the effect of Dragon’s blood on the expression of GSK-3? and the volume of hepatic glycogen and muscle glycogen in the liver and muscle of mice with DM. Method Selecting 120 mice of Kunming strain,and randomly dividing them into six groups:normal group,DM group,Dragon’s blood groups with three dosage 125,250,500 mg/(kg?d) and C4H11N5?HCl group. Dragon’s blood groups were given Dragon’s blood by introgastric (ig) everyday for 7 d. C4H11N5?HCl group were given C4H11N5?HCl 1 mg/(kg?d) by introgastric (ig) everyday for 7 d. The indices were observed and recorded. Result After given Dragon’s blood,the expression of GSK-3? was decreased (P
6.Relationship between thromboxane synthase gene and prostacyclin synthase gene expression and pulmonary hypertension induced by hypoxic hypercapnia
Haihuan ZENG ; Liangxing WANG ; Shaoxian CHEN ; Mingshan WANG ; Xiaofan FAN
Chinese Journal of Pathophysiology 2000;0(12):-
AIM: To study the effect of chronic hypoxic hypercapnia on gene expression of thromboxane synthase and prostacyclin synthase in pulmonary arterioles. METHODS: Sprague-Dawley rats were randomly divided into two groups: control group and hypoxic hypercapnic group. TXS mRNA and PGI 2-S mRNA were observed in pulmonary arterioles by in situ hybridization. RESULTS:mPAP, weight ratio of right ventricle (RV) to left ventricle plus septum(LV+S), contents of TXB 2 and 6-keto-PGF1 ? in plasma and lung and TXS mRNA in pulmonary arterioles were much higher in rats of hypoxic hypercapnic group than those of control group. Differences of PGI 2-S mRNA in pulmonary arterioles were not significant in two groups. Light microscopy showed hypertrophy of vessel smooth muscle cells and vessel cavity straitness were found in hypoxic hypercapnic group. CONCLUSION: Changes of gene expressions of thromboxane synthase and prostacyclin synthase and imbalance of TXA 2/PGI 2 may play an important role in hypoxic hypercapnic pulmonary hypertension.
7.Research on traditional Chinese medicine listed corporate social responsibility evaluation ;form 2012 to 2014 based on co-word analysis method
Yingying WANG ; Qi LI ; Chen ZHU ; Xiaofan WANG
International Journal of Traditional Chinese Medicine 2016;(2):105-109
An empirical study on the analysis of the social responsibility information which includes corporate social responsibility reports, annual reports and official website social responsibility part, of 62 selected Chinese listed corporate is performed using co-word analysis. We have clustered 39 key words which refined from the social responsibility management information into five index, which are characteristics of traditional Chinese medicine industry, cultural, quality, operation and sustainable development. The quality of construction, cultural products and characteristics of traditional Chinese medicine industry itself are the hot social responsibility information, and also can be used as key factors in the enterprise brand evaluation of traditional Chinese medicine.
8.A New Compound with Anti-oxidative Activity from Seeds of Jatropha curcas
Ling LI ; Xinluan WANG ; Xiaofan LI ; Naili WANG
Chinese Herbal Medicines 2010;02(4):245-247
Objective To search for chemical constituents with anti-oxidative activity from seeds of Jatropha curcas.Methods DPPH radical scavenging assay was used to screen fractions or constituents with anti-oxidative activities.Active fractions were separated by varied chromatography and then identified on the basis of physiochemical properties and spectroscopic methods.Results The n-butanol layer of ethanol extract from the seeds of J.curcas showed stronger activity than other fractions and was studied further.A new compound was isolated from this active layer, and its structure was identified as jatrophasin A (3,4,4',5'-tetrahydroxyl-3'-methoxyl-bisepoxylignan, 1).It showed stronger anti-oxidative activity compared with resveratrol.Conclusion Compound 1 is a new compound which has never been reported with strong anti-oxidative activity.
9.Application of prospectively electrocardiograph-gated 128-slice spiral CT angiography in children with complex congenital heart disease
Xiaofan ZHANG ; Lihong ZENG ; Zhiwei WANG ; Fang WANG
Chinese Journal of Radiology 2013;47(8):739-744
Objective To evaluate the prospective electrocardiograph (ECG)-gated 128-slice spiral CT angiography in the diagnosis of complex congenital heart disease and airway abnormality in children.Methods Eighty children with congenital heart disease received prospective (n =40) or retrospective ECG-gated 128-slice spiral CT angiography (n =40).All of the patients underwent ultrasound cardiogram (UCG) within one week before CTA exmination.The image quality and the effective radiation dose were statistically analyzed using independent samples t test and x2 test.The surgical results were taken as the diagnostic standards,and the preoperative prospective and retrospective CT angiography data were compared with UCG results using x2 test.Results The effective dose of prospective ECG-gated CT angiography[(1.00 ± 0.26)mSv] was reduced by 86% as compared with the retrospective ECG-gated CT angiography[(7.37 ± 0.52) mSv] (t =69.296,P < 0.01).Image quality was graded 0 in none patients,graded 1 in 2 patients who underwent prospective ECG-gated CT angiography,graded 2 in 8 and 1 patient who received prospective and retrospective ECG-gated CT angiography respectively,and graded 3 in 30 and 39 patients who underwent prospective and retrospective ECG-gated CT angiography,respectively.There was no significant difference in image quality between prospective and retrospective ECG-gated CT angiography (x2 =0.044,P > 0.05).The definitive diagnosis of extracardiac vascular anomalies was made in 98.3%(59/60) of patients by using prospective and retrospective ECG-gated CT angiography,which were significantly superior to UCG results[(76.7% (46/60),76.7% (45/59),respectively] (x2 =13.144,12.644,P < 0.01),and there was no significant difference in the definitive diagnosis between prospective and retrospective ECG-gated CT angiography (x2 =0.001,P > 0.05).The definitive diagnosis of the cardiac/large-vessel malformations was made in 100% of the patients by both prospective and retrospective ECG-gated CT angiography,and there was no significant difference between 128-slice spiral CT angiography results and UCG results [97.2% (35/36),97.3% (36/37),respectively] (x2 =1.014,0.001,P >0.05).In the cardiac malformations,the definitive diagnosis by prospective and retrospective ECG-gated CT angiography was 88.7 % (47/53) and 92.5 % (49/53),and there was no significant difference between 128-slice spiral CT angiography results and UCG results [98.1% (52/53),98.1% (52/53),respectively](x2 =3.824,1.889,P > 0.05),and no significant difference in the definitive diagnosis was observed between prospective and retrospective ECG-gated CT angiography (x2 =0.442,P > 0.05).In addition,the 128-slice spiral CT angiography detected airway abnormality in 9 cases who underwent prospective or retrospective ECG-gated CT angiography.Conclusion The prospective ECG-gated 128-slice spiral CT angiography exhibits great application value in the preoperative diagnosis of complex congenital heart disease,which helps to develop surgical program and evaluate surgical risks.
10.Effect of hypoxic precondition on apoptosis of hepatic ischemia reperfusion with the hepatectomy of transplanted hepatic cancer models in SD rants
Xiaofan HAN ; Peijian ZHANG ; Pengfei LI ; Jian WANG ; Tongmin XUE
International Journal of Surgery 2014;41(1):18-23,封3
Objective To investigate the effect of Heat shock protein 70 induced by hypoxic precondition on apoptosis of the remnant livers after the hepatectomy of transplanted hepatic cancer models in SD rants and it's possible mechanisms.Methods Sixty SD rats of transplanted hepatic cancer models were divided into group A (sham operation group),group B (IR + hepatectomy group),and group C (hypoxia precondition + IR + hepatectomy group),with 20 rats in each group.C group was given 10% oxygen atmosphere for 90 minutes before operation,In 15 minutes of hepatic vascular occlusion with pringle method,Left lateral of liver which tumor was located was resected.At 1,8,12,24 hours after operation,Five rats of each group were killed respectively,then the remnant liver tissues were sampled to measured the hepatocytes apoptosis rate with flow cytometry,expression of heat shock protein 70 (HSP70) and Bax were detected by Western blotting.The serum AST and ALT activities were measured by an automatic analyzer.The histological changes of the hepatocytes were also observed by optical microscopy.All the data were statistically analyzed.Results (1) Compared with A and B group,the HSP70 expression increased obviously in C group at each time point (all P < 0.05).The protein showed a weak expression in group A and B group,while the index had no significant differences between two groups (P > 0.05).(2) In B group compared with A group,the expression of Bax and the hepatocytes apoptosis rate were significantly increased (all P < 0.01 or P <0.05).However,amplitudes of the above changes in C group were significantly lower than those of B group (all P < 0.05).(3)The liver function was improved in group HP.The pathological examination showed that the liver tissues in A group were general normal and in C group were showed mild changes,but in B group presented evident pathological changes.Conclusions HP can protect against ischemia-reperfusion injury after the hepatectomy of transplanted hepatic cancer models in SD rants,one of possible mechanisms is that HP can induce HSP70 expression at great intensity,which may decrease expression of Bax protein and the apoptosis of hepatocytes.