1.The Primary Discussion of the Medical Service Safeguard of College Students in China
Chinese Journal of Medical Education Research 2003;0(02):-
Following the development of the socialist market economy and the reformation of the medical safeguard system and the improvement of the higher education reformation,the shortcoming of the medical safeguard system of college students which has started in the period of planned economy has become visible.Through the narration of present situation and the analysis of the reasons to the domestic college students'medical safeguards,this article suggests that our government should establish university student medical service safeguard system which is a perfect and multi-level system and brings the university students'medical safeguard system into the national society medical service safeguard.At the same time,we must strengthen university students'realization of medicine guarantees so as to guarantee them to complete their studies successfully
2.Value of immunohistochemistry in diagnosis and differential diagnosis of ovarian tumors.
Chinese Journal of Pathology 2009;38(4):280-284
Adenocarcinoma, Mucinous
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metabolism
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pathology
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Calbindin 2
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Carcinoma, Endometrioid
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metabolism
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pathology
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Diagnosis, Differential
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Female
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Humans
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Immunohistochemistry
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methods
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Inhibins
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metabolism
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Keratin-7
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metabolism
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Mucin-1
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metabolism
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Ovarian Neoplasms
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metabolism
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pathology
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S100 Calcium Binding Protein G
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metabolism
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Sex Cord-Gonadal Stromal Tumors
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metabolism
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pathology
4.Correlation of Apoptosis of Peripheral Blood Mononuclear Cell with Plasma 8-iso-prostaglandin F_(2?) in Neonates with Hyperbilirubinemia
dong, ZHOU ; xin, XIAO ; li-li, KANG
Journal of Applied Clinical Pediatrics 2003;0(10):-
Objective To explore the correlation of the apoptosis of peripheral blood mononuclear cell (PBMC) with plasma 8-iso-prostaglandin F2? (8-iso-PGF2?) level in order to confirm the peroxidation damage of hyperbilirubinemia in neonates with jaundice.Me-thods One hundred and twenty-nine neonates who were 2 to 7 days old were divided into 4 groups:slight jaundice (43 cases),moderate jaundice (38 cases),serious jaundice (18 cases),and healthy control(30 cases)groups.Plasma 8-iso-PGF2? levels were assayed by enzyme immunoassay(EIA),and the apoptosis rates of PBMC were determined by flow cytometry.Results 1.There was no significant difference in the apoptosis rate of PBMC between normal and slight jaundice neonates (P=0.108);apoptosis rate of PBMC was increasing with the aggravation of jaundice.2.Plasma 8-iso-PGF2? level in normal neonates was 14.74?6.71 ng/L,there was no difference between normal neonates and neonates with slight jaundice(P=0.502).Plasma 8-iso-PGF2? levels in neonates with moderate and serious jaundice were much higher(Pa=0).3.Positive correlation existed between plasma 8-iso-PGF2? level and PBMC apoptosis rate (r=0.602 P=0).Conclusions Hyperbilirubinemia can induce peroxidation damage,resulting in increase of PBMC apoptosis.Plasma 8-iso-PGF2? level can accurately eva-luate the peroxidation damage in neonates with jaundice.
5.The relationship between T lymphocyte subsets changes and the zoster associated pain in aged patients with acute herpes zoster
Erdan AN ; Wangpin XIAO ; Zongli ZHOU ; Li SUN
Chinese Journal of Geriatrics 2011;30(9):757-759
Objective To study T lymphocyte subsets levels in acute zoster patients and investigate its relation to the zoster associated pain.MethodsAccording to the visual analogue scales(VAS) in the acuter phase, 60 patients with herpes zoster were divided into two groups: group A (VAS≤6) and group B (VAS>6). According to the follow-up results, patients were divided into another two groups: group C (PHN not developed) and group D (PHN developed). 25 healthy volunteers with a similar age and gender range as the patients were recruited as control group. T lymphocyte subsets were detected by fluorescence-activated cell sorter (FACS). ResultsThere was no significant difference in gender and age between groups (P>0.05). T lymphocyte subsets were significantly decreased in four groups compared with the control group (P<0.05), and the CD4 +subsets in group B were significantly decreased compared with group A (P<0.05). The CD4 +/CD8 + ratios were significantly higher in group A and C than in control group, higher in group A than B and higher in group C than in group D (P<0.05). The visual analogue scales(VAS) in group D were significantly higher than in group C (P< 0.05).Conclusions Cellular immunity function is decreased with the lower percent of the T lymphocytes subsets in the elderly patients with acute herpes zoster, especially in severe patients. The CD4 +/CD8 + ratios and the visual analogue scales may be associated with the the risk of post herpetic neuralgia.
6.Interaction among Several Effective Chemical Compositions in Chinese Material Medicine on Cell Line S180
Chunfen XIAO ; Li ZHOU ; Zhaowen LOU
China Pharmacy 2001;0(09):-
OBJECTIVE:To observe the effects of Galangin,Magnolol,Curcumin,Camptothecine,Matrine and Ginsenoside Rg1 on cell line S180 and the interaction of two-drug combination and three-drug combination.METHODS:The inhibitions of effective chemical compositions(ECCs)in Chinese material medicine on S180 cells were measured by MTT assay.The principle of the interaction between various ECCs and the possibility of drug combination were discussed.The sum of fractional inhibitory concentration(SFIC)and ostensible inhibition(OI)methods were used for evaluation of the interaction between various ECCs.RESULTS:Both the combination of Camptothecine and Matrine,and the combination of Camptothecine and Galangin by 1:1 proportion showed obvious synergism.IC50 of the combination of Camptothecine and Matrine is 2.918? g? mL-1,IC50 of the combination of Camptothecine and Galangin is 56.49? g? mL-1.Combination of all three compounds and other combination of two compounds showed antagonism.CONCLUSION:Synergistic and antagonistic effects exist in combinations of ECCs in Chinese material medicine.
7.Analysis of CT Pathology and Clinical Manifestation of Lumbar Lateral Recess Stenosis
Dongmin XIAO ; Jiangnan ZHOU ; Kanghua LI
Journal of Chinese Physician 2000;0(12):-
Objective To explore the normal number of lumbar lateral recess and the relationship between the CT pathology and clinical manifestation in the patients who suffered from lumbar lateral recess stenosis. Methods Lumbar specimen of 15 normal adult corpse and 20 healthy volunteers were observed, and the anterior and posterior(AP) sagittal diameters of normal lumber lateral recess were measured. The CT pathology and clinical manifestation of 174 patients who suffered from lumbar lateral recess stenosis were analysed. Results At the levels of L1 and L2, the lateral recess was found in about 34% normal persons.At the levels of L3 to S1, the lateral recess was found in all healthy persons.All patients who suffered from lumbar lateral recess stenosis had narrow AP sagittal diameters of lumbar lateral recess (
8.Effect of Frog and Suckling Pig Skin on Wound Healing in Deep Burn
Bosheng ZHOU ; Jun TAN ; Xiao LI
Journal of Chinese Physician 2001;0(01):-
Objective To evaluate the effect of live frog skin in the treatment of deep partial thickness and full thickness burn. Methods 159 burned patients were randomly divided into two groups: wounds treated with frog skin or suckling pig skin. Wounds were covered by frog skin(35 cases) or by suckling pig skin(31 cases) after surgical debridement or when the crust began to dissolve for patients with deep partial thickness burns, and by frog skin (49 cases) or by sucking pig skin(44 cases) after surgical debridment or autologous skin grafting and escharetomy for patients with full thickness burns. There was no significant difference between the two groups in mean age, burn area and burn type. Results Compared with the suckling pig skin, frog skin could remarkably decrease days of wound recovery and antibiotics administration, and reduced incidence of wound infections and rejection in patients with full thickness burns. Conclusions Frog skin possessed more powerful anti-infection ability, and rare rejection phenomenon in the treatment of burn wounds. It may be a suitable biological dressing for burn wounds.
9.Clinicopathological characteristics of clear cell type meningioma.
Xiao LI ; Ru-jun XU ; Hong ZHOU
Chinese Journal of Oncology 2011;33(9):685-686
Adolescent
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Adult
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Aged
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Diagnosis, Differential
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Ependymoma
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pathology
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Female
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Follow-Up Studies
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Humans
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Immunohistochemistry
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Magnetic Resonance Imaging
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Male
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Meningeal Neoplasms
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diagnostic imaging
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metabolism
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pathology
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surgery
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Meningioma
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diagnostic imaging
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metabolism
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pathology
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surgery
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Mucin-1
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metabolism
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Oligodendroglioma
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pathology
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Tomography, X-Ray Computed
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Vimentin
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metabolism
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Young Adult
10.Clinical application of serological detection of Chlamydia pneumonia in patients with acute coronary syndrome
Lvmeng ZHOU ; Yan XIAO ; Zhongmei LI
International Journal of Laboratory Medicine 2015;(8):1080-1081
Objective To evaluate the application of serological detection of Chlamydia pneumonia (Cpn) in patients with acute coronary syndrome (ACS) .Methods From Oct .2012 to Oct .2013 ,80 patients with ACS (ACS group) and 80 healthy subjects (control group) were enrolled and detected for Cpn DNA .According to the detected results ,ACS patients were divided to chlamydia group and non‐chlamydia group .Serum levels of tumor necrosis factor α(TNF‐α) ,C reaction protein (CRP) ,intercellular cell adhe‐sion molecule‐1 (ICAM‐1) and lipoprotein were also detected .Results In ACS group ,53 cases were Cpn positive and 27 cases were Cpn negative ,and in control group ,7 cases were Cpn positive and 83 cases were Cpn negative ,which were with statistical difference between the two groups (P<0 .05) .Serum levels of TNF‐α,CRP ,ICAM‐1 ,total cholesterol ,triacylglycerol and low density lipo‐protein cholesterol were higher in chlamydia group and that of high density lipoprotein cholesterol was lower than non‐chlamydia group (P<0 .05) .Conclusion Chlamydia pneumoniae infection might be correlated with ACS .Chlamydia pneumoniae infection could be involved in disease development by increasing levels of inflammatory cytokines in ACS patients ,and further improve serum lipid levels .