Objective:To observe the clinical effect of piribedil and madopar on Parkinson's disease ( PD) . Methods:Totally 58 patients with PD were divided randomly into the treatment group (29 cases) and the control group (29 cases). Piribedil and madopar were used in the treatment group, while only madopar was applied in the control group. Therapeutic effect of both groups was evaluated by UPDRS at the end of 6 courses. Results:The decrease of UPDRS after the remedy in the treatment group was more significant than that in the control group (P<0. 05), and the total effective rate in the treatment group(89. 7%) was significantly higher than that in the control group(65. 5%)(P<0. 05). Conclusion:The clinical effect of piribedil combined with madopar on PD is superior to that of madopar alone, therefore, the combination use is a useful method in the treatment of PD with the value of popularization and applica-tion.

BACKGROUND:Recently, minimal y invasive techniques obtained more attention. Some new minimal y invasive methods have been used in the treatment of spine fracture and provide new chal enges for conventional open surgery. OBJECTIVE:To discuss the clinical efficacy of conventional posterior open pedicle screw fixation versus minimal y invasive operation (using Mast Quadrant System and Sextant percutaneous pedicle screw fixation) for treating single-segment thoracolumbar fractures without neurological damages. METHODS:A total of 94 cases of single-segment thoracolumbar fracture without neurological damages, who were treated in Department of Spine Surgery, Liuzhou Worker’s Hospital in China from January 2012 to January 2013, were enrol ed in this study. According to patients’ conditions and wil ing, they were divided into open fixation group, Quadrant fixation group and percutaneous Sextant fixation group. Perioperative index, clinical efficacy, and imaging results were observed and compared among different groups. RESULTS AND CONCLUSION:Intraoperative blood loss, incision length and length of stay were better in the Quadrant fixation group and percutaneous Sextant fixation group than in the posterior open fixation group (P<0.05). A total of 94 patients were fol owed up for 6 months. No cases of nerve damage, slippage or breakage of implants were found. The anterior vertebral body height, Cobb’s angle, and sagittal index were significantly improved postoperatively compared to pre-operation in al three groups (P<0.05), but there was no significant difference in the three groups (P>0.05). Postoperative Visual Analog Scale scores and Oswestry Disability Index were better in the two minimal y invasive groups than in the conventional open fixation group (P<0.05). These results suggested that compared with conventional open operation, minimal y invasive operation (Mast Quadrant System and Sextant percutaneous pedicle screw fixation) in the treatment of thoracolumbar fractures not only can achieve similar imaging result, but has smal incision, less blood loss, quick recovery, high safety, and obtains good clinical therapeutic outcomes. In the case of strict surgical indications, minimal y invasive method is an ideal choice in treating thoracolumbar fractures without neurological damages.

Adult ; China ; epidemiology ; Congenital Abnormalities ; epidemiology ; Female ; Humans ; Incidence ; Infant, Newborn ; Maternal Age ; Pregnancy ; Time Factors

Objective To study the clinical efficacy of Roukouwuwei Wan in the treatment of schizophrenia and its effect on serum superoxide dismutase, malondialdehyde and nitric oxide.Methods 84 cases of patients with schizophrenia were enrolled in our hospital from September 2015 to June 2016,according to coin-casting method divided into observation group and control group,42 cases in each group.The control group was treated with conventional regimen, and the observation group was treated with Rouku Wuwei Pills on the basis of control group.The quality of life, serum SOD, MDA and NO were measured before and after treatment,the clinical efficacy and side effects were analyzed.Results After treatment, the total effective rate of the observation group was significantly higher than the control group (P<0.05).After treatment,the scores of physical life,social function,mental health and physical health of the observation group were significantly higher than the control group ( P <0.05 );The levels of superoxide dismutase, malondialdehyde and nitric oxide in the observation group were significantly lower than the control group (P<0.05).The adverse reaction rate in the observation group was significantly lower than the control group (P<0.05).Conclusion The treatment of schizophrenia patients with Roukouwuwei Wan can reduce the levels of SOD,MDA and NO, improve the quality of life of patients, the clinical efficacy is good and reduce the incidence of adverse reactions.

Objective To assess the value of plug mesh tension free hernia repair in the treatment of abdominal external hernia. Methods 123 tension free repairs of hernia in 115 patients performed in our hospital from April 1988 to May 2000 were retrospectively reviewed. 50 4% (58/115) of cases were complicated by diseases such as cardiopulmonary dysfunction, hypertension, diabetes mellitus, prostate hypertrophy, cirrhotic ascites and thrombocytopenia. Results All patients had healing by first intention with no incisional infection or death , and they were discharged 3～7 days after operation(90% of patients were discharged 3 days after operation).90 4% of patients were followed up with an average of 20 months (1～25 months). There was no recurrence during the follow up.Conclusion Plug mesh tension free repair has the advantages of less trauma, little postoperative discomfort, rapid recovery and low recurrent rate.

AIM: To approach the best therapeutic measures after allochthonous intermingled with autogenous bone transplantation in children with tumor-like legion. METHODS: Forty children received bone transplantation between from March 2003 to March 2006 were selected from First Hospital Affiliated to Zhengzhou University. The guardians of Children all knew and agreed with the items. Subjects were divided into two groups according to the bone grafts with 20 children in each group: Compound transplantation group and autoplastic transplantation group. ① Subjects in compound transplantation group were transplanted with compound bone of allochthonous bone, autogenous bone and marrow with 160 thousands of gentamicin, 400 mg of vacocin and 5 mg of dexamethasone added. Allochthonous bone was obtained from dried radiosteriliaed bone, which was made by Shanxi Aorui Biomaterial Co., Ltd. Autogenous bone was gotten from the iliac bone of children. ② Subjects in autoplastic transplantation group were transplanted with simple illac bone got from subjects. Meanwhile, 16 thousands of gentamycin was adopted in the transplantation without using dexamethasone. ③ 5 mg of dexamethasone was added in to the allochthonous bone used for the surgery of subjects in compound transplantation group, and intervenous drop infusion of hormone was given to subjects after the surgery at proper dose, while children in autoplastic transplantation group received no hormone during and after the surgery. ④ Post-operation draining was performed, and the draining flow within 24 hours less than 20 mL was taken as the index of extubate. ⑤ The allochthonous bone and autoplastic bone were immersed into 160 thousands of gentamicin and 400 mg of norvancomycin used for patients in the compound transplantation group. Patients in both groups were administrated with antibiotic drugs of blue mold for fear of infection. ⑥ The duration of recovery to normal body temperature, leukocyte count and erythrocyte sedimentation rate (ESR) as well as the time of reservation of drainage tube of patients in both groups were observed after the surgery after operation, and follow-up was conducted regularly. RESULTS: Totally 40 patients were involved in the analysis of results, and no one withdrew from the study. ① The duration of recovery to normal body temperature, leukocyte count and ESR as well as the time of reservation of drainage tube of patients in compound transplantation group were longer than those in autoplastic group [(10.95?2.63,13.85?2.68,25.90?2.53,13.15?3.01) days;(6.95?1.57,8.80?1.96,15.30?2.27,6.40?1.98) days,P

Abscess ; complications ; Bacterial Infections ; Humans ; Infant ; Infant, Newborn ; Male ; Paralysis ; complications ; Proctitis ; complications

Adult ; Computer Terminals ; Humans ; Male ; Paper ; Reading ; Students, Medical ; Workload

Humans ; Stomach Neoplasms ; diagnostic imaging ; Tomography, X-Ray Computed

Aromatase Inhibitors ; adverse effects ; Arthralgia ; chemically induced ; therapy ; Humans ; Integrative Medicine