1.Review and Analysis of Processing Technology and Active Ingredients of Medicinal Leech
China Pharmacist 2014;(10):1760-1762
Theancientandmodernprocessingmethods,activeingredientresearch,andqualitycomparisonbeforeandafterthe processing of medicinal leech were reviewed in the paper. Combined with the results of anticoagulation test on Whitmania pigra Whit-man, the article drew a conclusion that different varieties of medicinal leech had different active ingredients of anticoagulation, Whitma-nia pigra Whitman had active ingredients of anticoagulation with promising heat stability, and the processing technology should be dealt with according to the clinic use.
2.Effects of Rehabilitation Nursing on Motor Function and Activities of Daily Living of Stroke Patients
Chinese Journal of Rehabilitation Theory and Practice 2012;18(12):1175-1177
Objective To explore the effect of rehabilitation nursing intervention on motor function and activities of daily living of patients with stroke. Methods 140 stroke patients were randomly divided into control group (n=70) and rehabilitation group (n=70). The control group received conventional drugs of neurology and nursing, the rehabilitation group received rehabilitation nursing intervention in addition.Before and 5 weeks after treatment, the motor function and activities of daily living (ADL) were assessed with Fugl-Meyer assessment (FMA) and modified Barthel index (MBI). Results There was no significant difference between 2 groups (P>0.05) before treatment. The scores of FMA and MBI were significantly higher in the rehabilitation group than in the control group (P<0.001) after treatment. Conclusion Rehabilitation nursing intervention can improve the patient's motor function and ADL recovery.
3.The progress study of tumor suppressor gene and apoptosis gene in nasal polyps.
Dan CHEN ; Lu CHEN ; Ling XIAO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(23):2099-2102
Nasal polyps is a common disease in clinical, with nasal mucosal inflammatory hyperplasia. However, the molecular mechanism of it is largely unknown. Tumor suppressor genes, proliferation and apoptosis related genes and cytokines play an important role in the formation and pathological development of nasal polyps. The expression level of tumor suppressor related proteins and receptors is not constant, high level of these expression can stimulate nasal mucosal proliferation, while low or lacking expression may facilitate nasal polyps cells apoptosis. Both proliferation and apoptosis make a big difference in nasal polyps formation and development. This article concludes the relationships between new progressions in nasal polyps pathogenesis and tumor suppressor genes and proliferation apoptosis genes, which not only helps practitioners deeply and comprehensively understand nasall polyps pathogenesis but promotes explorations to effective therapeutics.
Apoptosis
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Apoptosis Regulatory Proteins
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genetics
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Cytokines
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Disease Progression
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Genes, Tumor Suppressor
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Humans
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Nasal Mucosa
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Nasal Polyps
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genetics
4.Measuring diameters of thyroid arteries in Graves disease by improving theurapentic effect of intervention radiology
Haipeng XIAO ; Guorui CHEN ; Qibo LING
Chinese Journal of Microsurgery 2000;0(03):-
Objective In order to select appropriate size of embolizing granules and to achieve complete embolization and good therapeutic effect, the diameters of thyroid arteries in Graves disease was measured. Methods Multiple slides of embolized thyroid tissues from superior pole, body and inferior pole of resected thyroid glands were made. After being embeded and stained, diameters of arteries in various parts of thyroid glands were measured with microscope calipers (Olympus). Results Average diameter capillary network of the thyroid body gland adjacent to superior, infreior artery was 0. 12-0. 25 mm, and the smallest one was 0. 04-0. 11 mm. The diameter of isthmus was 0. 130. 15 mm. The average diameter of superior and inferior artery was 2- 5. 5 mm and 3. 0- 3. 75 mm measured by using interventional angiography Conclusion According to the diameters of arteries which were measured, complete embolization and good therapeutic effect can be achieved.
5.Effect of implanted sustain-released 5-fluorouracil during operation in patients with advanced rectal cancer
Ling DAI ; Xiaolin TIAN ; Xiao CHEN
Clinical Medicine of China 2011;27(4):430-433
Objective To assess the effect of intraperitoneal interstitial implant of Sustained-release 5-Fluorouracil during operation for advanced rectal cancer. Methods One hundred and four cases with advanced rectal cancer were enrolled into the study and divided into 3 groups: treatment group 1(n = 37), underwent combined hypotonic peritoneal chemo-hyperthermia and Sustain-released 5-fluorouracil implantation treatment during operation; treatment group 2(n = 34), underwent combined intraoperative hypotonic peritoneal chemohyperthermia and early postoperatively intraperitoneal chemotherapy treatment; and control group(n = 33),underwent peritoneal lavage during radical resection alone. Results Digestive tract toxicity in group 1 was significantly lower than that in group 2(2. 70% vs. 20. 59%, x2 = 9. 104, P < 0. 05). There were significant difference on 1 year survival rate among the three groups. The 2-year survival rate of group 1 was significantly higher than that in the control group (78. 37% vs. 48. 48%, x2 = 1. 297 ,P < 0. 05). After two years follow-up the 2-year local recurrence rate of group 1 was significantly lower than that in the control group(21.62% vs 32. 35 %, x2 = 7. 001, P < 0. 05). However, no significant difference was found compared to group 2, which was 32. 35%. Conclusion lntraperitoneal interstitial implant of Sustain-released 5-Fluorouracil during operation is an effective intraperitoneal chemotherapy with mild side effects for advanced rectal cancer.
7.Study on the response characteristics of the in vivo bladder detrusor to the cholinergic transmitter.
Xiao-Qing HUANG ; Xiao-Ran YE ; Ling CHEN
Chinese Journal of Applied Physiology 2008;24(3):360-362
Acetylcholine
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metabolism
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physiology
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Animals
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Cholinergic Agonists
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pharmacology
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Male
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Muscle Contraction
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drug effects
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physiology
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Muscle Relaxation
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drug effects
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physiology
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Muscle, Smooth
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drug effects
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pathology
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physiopathology
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Rabbits
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Random Allocation
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Receptors, Cholinergic
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physiology
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Synaptic Transmission
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drug effects
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Urinary Bladder
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drug effects
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innervation
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physiopathology
8.Determination of Residual Palladium in Bendamustine Hydrochloride by GFAAS
Dejun CHEN ; Dongmei ZHANG ; Song WANG ; Xiao LING
China Pharmacist 2016;19(9):1808-1809
Objective:To develop a method for the determination of palladium in bendamustine hydrochloride by GFAAS. Meth-ods:The sample was destroyed by heat, and the content of palladium was determined by GFAAS with the detection wavelength of 247. 6 nm. Results:The absorbance and the content of palladium showed a good linear relationship within the range of 20-60 ng· ml-1(r=0. 998 4). The average recovery of palladium was 102. 9%(RSD=1. 7%, n=9). Conclusion: The method is sensitive and simple, which can be used for the determination of palladium in bendamustine hydrochloride.
9.Clinical observation of diabetic retinopathy after transplantation of autologous stem cell in diabetic patients
Xiao-Lin, HAO ; Xiu-Ling, YE ; Zhong-Chen, ZHANG
International Eye Science 2014;(9):1702-1704
To observe the effect of autologous stem cell transplantation in diabetic retinopathy.
●METHODS:Totally 58 cases (116 eyes) who underwent autologous stem cell transplantation were confirmed as no diabetic retinopathy (18 eyes), mild non-proliferative diabetic retinopathy (NPDR) (41 eyes), mid-level NPDR (51 eyes); severe NPDR (6 eyes) by ophthalmoscope directly or indirectly and fluorescence fundus angiography (FFA ). Follow - up was 6 - 12mo, the changes of retinopathy were observed.
●RESULTS: The total effective rate of vision and retinopathy was 84. 4%, 76. 7%. The results of severe NPDR was statistically worse than the other groups ( P <0. 05).
●CONCLUSlON: The stable blood glucose level and improved pancreatic function after autologous stem cell transplantation might be helpful in diabetic retinopathy, the long effects need to be researched further.
10.ASSOCIATION OF HABITUAL CALCIUM INTAKE WITH BONE MASS IN PREMENARCHE CHINESE GIRLS
Ling WANG ; Yuming CHEN ; Guopeng HE ; Xincai XIAO ; Yixiang SU
Acta Nutrimenta Sinica 1956;0(03):-
Objective: To investigate the association of calcium intake with bone mass in premenarche girls. Method: Bone mineral density (BMD) and bone mineral content (BMC) at the whole body, lumbar spine (L1-L4) and left hip of 194 premenarche girls (10?1 years old) were measured by dual-energy X-ray absorptiometry (DEXA). Dietary calcium intakes were assessed by food frequency questionnaire and 3d weighed diet records. Results: Statistically significant positive correlations between daily calcium intake and bone bone mineral density (BMD) were or bone mineral content (BMC) at all studied bone sites were found (P