1.Preparation of ?-cyclodextrin Inclusion Compound of Volatile Oil from Danfu Tongmai Granules
Qiao'E XIE ; Shang LI ; Caihong XIAO ;
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Objective To study the inclusion conditions for volatile oil from Danfu Tongmai Granules.Methods With the utilization rate of volatile oil and yield rate of inclusion as indexes,the optimum inclusion conditions were selected by orthogonal design,and the inclusion compound was identified by TLC.Results The optimal inclusion conditions for volatile oil were as follows:a proportion of 1 ∶7(mL ∶g) for oil to ?-cyclodextrin,stirring for 4 hours at 40 ℃.TLC results showed that inclusion process was successful and the main components of volatile oil were similar before and after inclusion.Conclusion This methods can be used for producing ?-cyclodextrin inclusion compound on a large scale.
2.Studying Rational Use of Pediatric Prescribed Drugs in Outpatient Department in Accordance with International Indicators and DDDs Sequences Analysis
Yongxin XIAO ; Dong LI ; Shouxia XIE
China Pharmacy 2005;0(18):-
OBJECTIVE:To review drug use in the pediatric outpatient department of our hospital.METHODS:1000pediatric prescriptions during Aug.1to Aug.20,2004and another1000during Aug.1to Aug.20,2005were collected from the pediatric outpatient department of our hospital,and which were subjected to statistical analysis using international indicators of rational drug use and DDDs.RESULTS:The usage of injection accounted for12.3%in2004and11.4%in2005.The usage of anti-infectives stood at84.20%in2005,accounting for46.11%of total drug consumption sum.Azithromycin and cefaclor respectively dominated the first place on the lists of consumption sum and DDDs.CONCLUSION:The practice of Prescription Management Rules(trial)helps improving the use of injections in the pediatric outpatient department of our hospital.However,there are still many problems,which needs to be tackled in the application of anti-infectives and further intervention measures needs to be taken.
3.One case of acute arsenic poisoning by absorption through skin wound.
Xin LI ; Xiongbin XIAO ; Jinggui XU ; Li LI ; Lei XIE
Chinese Journal of Industrial Hygiene and Occupational Diseases 2014;32(2):138-138
Adult
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Arsenic Poisoning
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etiology
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Arsenicals
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Humans
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Male
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Skin
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injuries
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Skin Absorption
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Wounds and Injuries
4.Clinical features and treatment of paroxysmal supraventricular tachycardia in children
Li ZHANG ; Yun LI ; Tingting XIAO ; Lijian XIE ; Jie SHEN
Journal of Clinical Pediatrics 2017;35(7):488-490
Objective To explore the clinical characteristics and treatment of paroxysmal supraventricular tachycardia (PSVT) in children. Methods The clinical data of 67 children with PSVT were analyzed retrospectively, and the therapeutic effects of different treatments were compared. Results The clinical manifestations of infants were paleness, shortness of breath, irritability and sweating, and children showed chest tightness, palpitations, abdominal discomfort and fatigue. The curative effect of electric cardioversion, transesophageal atrial pacing, physical therapy, and drug therapy was statistically different (P<0.05), The different cardioversion rates of them were observed for the treatment of paroxysmal supraventricular tachycardia. The cardioversion rate of transesophageal atrial pacing, was the highest, and the rate of physical therapy was the lowest. There was no significant difference in the cardioversion rate between propafenone, digoxin and amiodarone. Conclusion The clinical manifestations of PSVT in infants are atypical and easily to be ignored. There are many methods for treatment of PSVT. The vagus nerve can be stimulated first, and, if no response, either drugs or electric cardioversion and transesophageal atrial pacing can be used. The cardioversion rate of transesophageal atrial pacing is higher. The drug effectiveness for the treatment of PSVT depends on many factors, and our choice of medication varies from person to person.
5.Epstein-Barr virus positive anaplastic-like plasmacytoma: report of a case.
Wen-sheng LI ; Xiao-ge ZHOU ; Jian-lan XIE
Chinese Journal of Pathology 2013;42(3):203-204
ADP-ribosyl Cyclase 1
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metabolism
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Aged
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Epstein-Barr Virus Infections
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Herpesvirus 4, Human
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isolation & purification
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Humans
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Interferon Regulatory Factors
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metabolism
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Ki-67 Antigen
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metabolism
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Male
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Nasal Cavity
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Nose Neoplasms
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metabolism
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pathology
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surgery
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virology
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Plasmacytoma
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metabolism
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pathology
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surgery
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virology
6.Temperature variation at the external root surface during Nd: YAG laser irradiation in the root canal in vitro.
Yuan-gao LI ; Xiao WANG ; Kexian XIE ; Dan LIU
West China Journal of Stomatology 2014;32(5):480-483
OBJECTIVETo assess the temperature variation of the root surface using Nd: YAG laser irradiation in the root canal with different power and to evaluate the safety of laser application on the periodontal region.
METHODSThirty extracted human teeth with single-roots were collected. The teeth were cross-sectioned in the cervical portion, standardizing the roots at a 12-mm length. The roots were used as specimen. The roots were radiographed in the buccal-lingual direction to measure the thickness of the proximal walls, by means of a digital radiographic system. The specimens were divided into three groups according to the laser potency (1.5, 3.0, and 4.5 W). Each group was subdivided into two subgroups according to laser frequency (15 and 30 Hz). With the Nd: YAG laser irradiation for 20 s, the temperature variation of the root surface was monitored by thermocouples located at different parts of the root external wall and recorded by digital thermometers.
RESULTSThe groups irradiated with 4.5 W presented the greatest temperature variation (above 10°C), followed by 3.0 and 1.5 W. The temperatures were statistically different (P < 0.01). The groups irradiated in the same potency, regardless of whether 15 Hz or 30 Hz was used, presented with no statistical difference (P > 0.05). The apical half of the root presented statistically higher temperature rises than the cervical half of the root (P < 0.01).
CONCLUSIONThe temperature variation of the root surface was associated with laser power, irradiation time, and the thickness of dentin. Application of Nd: YAG laser in the root at 1.5 W for 20 s can safely be used in endodontic treatment.
Dental Pulp Cavity ; Dentin ; Humans ; In Vitro Techniques ; Lasers ; Lasers, Solid-State ; Root Canal Therapy ; Temperature ; Tooth Root
7.Determination of Paeoniflorin in Cervipower Capsules by RP-HPLC
Qiwen LU ; Jian LI ; Yanting XIE ; Peng XIAO ;
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(03):-
Objective To establish the RP-HPLC method for the determination of paeoniflorin in Cervipower Capsules. Methods Diamonsil~(TM)C_(18)column was used,with a mobile phase of A(methanol)-B(0.025 mol?L~(-1)disodium hydro- gen phosphate,adjusting pH being 7.4 with 0.025 mol?L~(-1)potassium dihydrogen phosphate),and with a gradient elu- tion,the flow rate was 1.0 mL?min~(-1),the detection wavelength was 230 nm,and the column temperature was 30℃. Result The linear range was 15.10~105.70?g?mL~(-1),r=0.999 9,and the average recovery for paeoniflorin was 100.1%,with RSD 1.94 %(n=9).Conclusion The method is accurate and reproducible,and can be used to deter- mine the content of paeoniflorin in Cervipower Capsules.
8.The clinical feature and gene mutation of three pedigrees with spinocerebellar ataxia MA
Yingwen MA ; Chunli XIE ; Hui LI ; Shuping XIAO ; Haiying ZHU
Journal of Chinese Physician 2011;13(2):177-180
Objective To investigate the clinical features and the gene mutation of patients with spinocerebellar ataxia type3 and type7.Methods The trinucleotide repeat mutations were detected by polymerase chain reaction (PCR),agarose gel electrophoresis method,and DNA sequencing in 13 patients,4 related members and 4 common members from 3 spinocerebellar ataxia families.Results Among the 13 patients,four patients had SCA3/MJD(CAG) n expansion mutation(n = 65 ~ 74),nine patients had SCA7 allele expansion for 40 ~ 52 times.Patients with type 3 or 7 showed significant difference in nervous system injury.Conclusion The difference of clinical feature might be used in diagnosis of SCA3/MJD and SCA7,but genotype determination would be the only method of definite diagnosis.
9.Case-control study on cognitive function of 87 children with behavior problems
Changguo XIE ; Yanfeng LI ; Ruilan ZHOU ; Changshui CAO ; Fuxiang XIAO
Chinese Journal of Behavioral Medicine and Brain Science 2010;19(8):713-715
Objective To compare the cognitive function of children with behavior problems and normal children. Methods 87 children with behavior problems were choosed as study group,according to Rutter' s Children Behaviour Qestionnaire. And 87 normal children were choosed randomly as normal control. Chinese Wechsler Intelligence Scale for Children (C-WISC) ,Clinical Memory Scale (CMS) ,Number Cancellation Test (NCT) and the Forth Exceptional Test (FET) were adopted to assess the cognitive function of children in two groups. Results Compared with normal control, arithmetic scale ( ( 10.40 ± 3.02 ) vs ( 12. 13 ± 3.26 ) ), verbal IQ ( ( 121.55 ±12.54) vs ( 129.40 ± 13.98) ), object assembly scale ( ( 9.98 ± 2.79 ) vs ( 11.70 ± 2.78 ) ), performance IQ((97.40±10.84) vs ( 103.93 ±14.22)),full IQ ((112.28±11.14) vs (119.03 ± 12.57)),verbal comprehension IQ ( ( 110.48 ± 11.23 ) vs ( 115.80 ± 12.31 ) ), memory/concentration IQ ( ( 101.25 ± 11.66 ) vs ( 109.40 ± 15.45 ) ),the net scale ( (67.05 ± 33.85 ) vs ( 88.72 ± 22.51 ) ) and error rate( ( 32.27 ± 35.77 ) %vs ( 15.41 ± 10.35 ) % ) were lower in children with behavior problems ( all P < 0.05 ). In study group, the total scale of Rutter' s Children Behaviour Qestionnaire was negatively correlated with memory/concentration IQ, and with net scale(r = - 0. 335, - 0. 367, P < 0.05 );but it was positively correlated with error rate (r = 0. 333, P < 0.05 ). Conclusion Cognitive defects may exist in children with behavior problems.
10.Pyothorax-associated lymphoma: report of a case.
Li-hua WU ; Jian-lan XIE ; Xiao-ge ZHOU
Chinese Journal of Pathology 2009;38(3):205-206
Adult
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Antigens, CD20
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metabolism
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Empyema, Pleural
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complications
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diagnostic imaging
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pathology
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virology
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Epstein-Barr Virus Infections
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Humans
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Ki-67 Antigen
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metabolism
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Lymphoma, Large B-Cell, Diffuse
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metabolism
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pathology
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surgery
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virology
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Male
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Pleural Neoplasms
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complications
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metabolism
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pathology
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surgery
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virology
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Radiography