1.Curative Effect of Lactoferrin on Repeated Respiratory Infection in Children
wei, PAN ; jing, LUO ; jin-sheng, XU ; xiao-ming, BEN
Journal of Applied Clinical Pediatrics 2006;0(22):-
Objective To observe the immunologic effect of lactoferrin on repeated respiratory infection(IRRI) in children.Methods Ninety-eight cases of IRRI were divided into two groups randomly.The control group (48 cases)were treated with routine therapy.The treatment group(50 cases) were treated with lactoferrin based on routine therapy for 2-3 months.T cell subgroup,immunoglobulin and complements were determined before and after treatment.Results Total effective rates in treatment group and control group were 86% and 22.9% respectively.The therapeutic efficacy in treatment group was significantly higher than that in control group(P
2.Clinical Analysis of Complications of 115 Children with Serious Pneumonia with Ventilatory Support
xiao-min, WANG ; jing-fu, HUANG ; jin-sheng, ZHAO
Journal of Applied Clinical Pediatrics 1994;0(04):-
Objective To explore the clinical characteristics of children with serious pneumonia with ventilatory support,and combined with heart failure,encephalopathy,hyponatramia,acute respiratory distress syndrome(ARDS) and multiple organ dysfunction syndrome(MODS).Methods One hundred and fifteen children(81 males,34 females) with serious pneumonia in ICU from Jul.2005 to Jul.2007 were reviewed,The duration of ventilation support was over 48 h.And blood electrolyte,blood gas,cerebrospinal fluid and CT were detected.Results Ninety-three cases had a good outcome,7 cases were given up,15 cases were dead.The complications included heart failure in 60 cases(52.17%);encephalopathy in 40 cases(34.78%),in which tics type in 38 cases(95%),apnea type in 11 cases(27.5%);hyponatremia in 42 cases(36.52%),of which tics type in 31 cases(73.81%),syndrome of inappropriate secretion of antidiuetic hormone in 27 cases(72.97%)resulted in hyponatremia;ARDS in 8 cases(6.96%),pa(O2)/FiO2
3.Application of cystatin C as an efficacious marker of renal function in kidney transplant recipients
Sheng-Hua WANG ; Xiao-Jing YANG ; Xiong ZOU ;
Chinese Journal of Laboratory Medicine 2003;0(11):-
Objective To assss the clinical significance of Cystatin C(Cys C)as a marker of renal function in kidney transplant patients especially when infection or acute rejection occured.Methods Among 65 renal transplant recipients the concentrations of serum Cys C and serum creatinine(Scr)were determined before and one month after the transplantation,and also in the day and next day of occurrence of infection or rejection.Meanwhile,30 healthy persons and 30 infected patients without kidney transplantations were served as control.Results The concentrations of Cys C were nearly equal between healthy persons and the infected patients without kidney transplantations(P = 0.32).The level of serum Cys C and Scr dropped quickly in the first 3 days after transplantation(decreased by 69.2%,74.7%,75.8% for Cys C and 38.4%,74.5%,81.4% for Scr)(P
4.Value of magnetic resonance cholangiopancreatography for diagnosis of pancreas divisum
Ai-Sheng DONG ; Chang-Jing ZUO ; Xiao-Hong LI ;
Academic Journal of Second Military Medical University 1985;0(06):-
Objective:To investigate the value of magnetic resonance cholangiopancreatography(MRCP)in the diagnosis of pancreas divisum by comparing with endoscopic retrograde cholangiopancreatography(ERCP).Methods:The MRCP and ERCP images of 8 patients with pancreas divisum were retrospectively analyzed.The diagnostic accuracy and findings by MRCP were compared with those by ERCP.Results:MRCP had a diagnostic accuracy of 87.5%(7/8)based on the result of ERCP.ERCP displayed the dominant dorsal pancreatic ducts in all 8 cases and ventral pancreatic ducts in 6 cases;MRCP also displayed the dominant dorsal pancreatic ducts in all 8 cases,but the ventral pancreatic ducts only in 3 cases.Conclusion:As a non-invasive technique,MRCP has important clinical value in the diagnosis of pancreas divisum.
5.Influence of rhIL and rhTPO on the number and quality of platelet and coagulability of whole blood in monkeys.
Xiao-Lan LIU ; Ling-Sheng SUN ; Jing HAO
Chinese Journal of Applied Physiology 2002;18(3):282-305
Animals
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Blood Coagulation
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drug effects
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Blood Platelets
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drug effects
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Female
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Haplorhini
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Humans
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Interleukin-11
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pharmacology
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Male
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Platelet Count
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Thrombopoietin
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pharmacology
7.Application of paclitaxel during trabeculectomy and its anti-proliferative effects
Jing, CHI ; Xiao-hua, MA ; Hong-sheng, BI ; Jing, GAO ; Zhong-en, LI
Chinese Journal of Experimental Ophthalmology 2011;29(1):43-47
Background The filtering surgery is the main method of treating glaucoma.Fibrosis of filtering bleb is a key cause of failure of operation.The study about application of anti-scaring drug in filtering surgery is a hotspot.Objective Present study was to investigate the anti-scaring effect of paclitaxel aher trabeculectomy.Methods Thirty-two adult clean domestic rabbits underwent standardized trabeculectomy and randomly divided into 4 groups.Normal saline solution was used beneath the scleral flap during trabeculectomy for 3 minutes in 16 eyes of 8 rabbits as controls.0.3 g/L mitomycin C,0.2 g/L paclitaxel or 0.3 g/L paclitaxel was administered at the same way respectively in other 3 groups.Intraocular pressure (IOP) was measured,and eye numbers with function blebs were compared among 4 groups at the 4th,7th,14th and 28th day after surgery.The opening of filtration tunnel and the number of inflammatory cells were observed by hematoxylin and eosin staining,and proliferation of new collagen fibers was evaluated by Masson trichrome method.This study complied with the Regulations for the Administration of Affair Concerning Experimental Animals by State Science and Technology Commission(version 1988). Results No significant differences were found in the change of lOP among 4 groups before operation(F=0.54,P=0.83)and the 4th day aher operation(F=0.57,P=0.87).The IOP value was statistically lower in 0.3 g/L mitomycin C group,0.2 g/L paclitaxel group and 0.3 s/L paelitaxel group than the normal saline solution group(P<0.05)with the lowest value in 0.3 s/L paclitaxel group in 7,14,28 days after operation(P<0.05).Functional filtering bleb was seen in all the rabbit eyes in the 4th day after operation.In 7,14,28 days after operation,the number of eyes with functional bleb wag evidently more in 0.3 g/L mitomycin C group,0.2 g/L paclitaxel group and 0.3 g/L paclitaxel group compared with normal saline group(P<0.05).The histological examination showed that the infiltration of inflammatory cells in filtering tunnel was much more obvious in normal saline solution group than the other groups with the most mild response in 0.3 g/L paclitaxel group.Masson trichrome revealed that proliferation of new collagen fibers in 0.3 g/L paclitaxel group was significantly decreased in comparison with those in other three groups at the 4th,7th,14th and 28th day after surgery(all P<0.05). Conclusion Paclitaxel can inhibit the inflammatory response and collagen fibrosis and therefore open the filtering tunnel after it be used topically during the glaucoma trabeculectomy.
8.A new aurone glycoside from Veratrum dahuricum (Turcz.) Loes. f.
Jing-gong GUO ; Yin-sheng CHEN ; Jing LI ; Tian-xiao WANG ; Sha-sha LI ; Yue CONG
Acta Pharmaceutica Sinica 2015;50(3):337-339
To study the chemical constituents of Veratrum dahuricum (Turcz.) Loes. f., a new aurone glycoside named as (Z)-7, 4'-dimethoxy-6-hydroxyl-aurone-4-O-β-glucopyranoside was isolated from the 95% ethanol extracts of the rhizomes and roots of Veratrum dahuricum (Turcz.) Loes. f. by repeated column chromatography on silica gel and recrystallization. Its structure was established by extensive spectroscopic analyses, and its cytotoxicities against HepG-2, MCF7 and A549 cell lines were measured in vitro.
Benzofurans
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isolation & purification
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Cell Line, Tumor
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Glycosides
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isolation & purification
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Humans
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Plant Roots
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chemistry
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Plants, Medicinal
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chemistry
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Rhizome
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chemistry
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Veratrum
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chemistry
9.Study on DNA expression profiles in renal biopsies of patients with IgA nephropathy.
Feng LI ; Ying-hao YU ; Jing-sheng XU ; Feng-hua LAN ; Yong-ze ZHUANG ; Zhi-yong ZHENG ; Hua-sheng XIAO
Chinese Journal of Pathology 2009;38(5):342-343
Adult
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Biopsy
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DNA
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genetics
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Female
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Gene Expression Profiling
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Glomerulonephritis, IGA
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genetics
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pathology
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Humans
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Kidney
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pathology
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Male
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Middle Aged
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Young Adult
10.Several thinking about the training of eight - year program medical students in clinical work and scientific research of ophthalmology
Yi-Sheng, ZHONG ; Shuo, XU ; Xiao-Hong, LIU ; Jing, WANG ; Xi, SHEN
International Eye Science 2016;16(6):1026-1028
?In allusion to the training requirements of eight-year program medical students, combining with our own experience in teaching this type of the students in ophthalmology, we have done some thinking about the training methods of eight-year program medical students in order to improving their comprehensive abilities of ophthalmology. Several suggestions are made in various aspects, including the study of the basic theory of ophthalmology, the training of doctor - patient communication skills, the training of basic clinical skills, the interest developments in ophthalmology subspecialty areas and the training of basic experiment skills.