Objective To explore the correlation between the need for cognitive closure and the way of coping with the disease in patients with hepatitis B cirrhosis. Methods 217 patients with hepatitis B cirrhosis were questionnaired by the Need for Cognitive Closure Scale and the Medical Coping Style Questionnaire (Chinese version). Results The total score of need for cognitive closure in separation and conversion disorder patients was (217.65 ± 31.23) points. The scores of face, yield and avoidance in the coping style were respectively (18.87±2.49) points,(13.21±1.53) points and (17.63±2.27) points. The score of face was significantly negatively correlated with the total score and all dimension scores of the need for cognitive closure(r=-0.421,-0.387,-0.405, P<0.05);the scores of yield and avoidance were positively correlated with the total score and all dimension scores of the need for cognitive closure (r=0.343-0.432, P<0.05). There were significant difference of the way of coping with the disease in the patients with different family income, payment method, course of disease (t=-3.080-3.490, P<0.05). Multiple regression analysis showed need for cognitive closure was influencing factor of way of coping with the disease in patients with hepatitis B cirrhosis. Conclusions The level of need for cognitive closure is in the high level in patients with hepatitis B cirrhosis, and influencing the way of coping with the disease.

A kind of simple portable electronic pulsometer based on piezoelectric sensor is designed, which constituted with single-chip microcomputer AT89S51. The piezoelectric sensor is used to transform pulse beating into electrical signal. Because the signal is very weak, the regular pulse profile is only obtained after enlargement and reshaping. Three-operation-amplifier circuit is used to magnify the weak signal from sensor, and the one-order low-pass filter is used to reshape the signal to get rid of miscellaneous signals. After timing and counting by the single-chip microcomputer, the pulse number is directly shown on light-emitting diode tubes through decoding circuit. The norm time generation circuit, a single steady trigger consisted of 555 integrated circuit chip mainly, set the standard time. The single-chip microcomputer AT89S51 circuit control the enlargement and reshaping of the original signal and time trigger. This portable electronic pulsometer has many advantages, such as simple structure, steady and reliable working, direct number display, low error (

A kind of personal computer-based monitoring system with piezoelectric sensor for pulse signal is developed,which constitutes with single-chip microcomputer AT89S52 and personal computer. The integrated polyvinylidene difluoride piezoelectric pulse sensor is used to pick up the pulse signals of examined person and transfer to electric signal under processing. The weak signal from the sensor is enlarged through three-operation-amplifier circuit. The magnified pulse signal is converted digital pulse signal through ADC0809 chip and the pulse number can directly show on LED tubes through the coding circuit. At the same time the digitalized pulse signal is delivered to personal computer through serial communication interface of single-chip microcomputer AT89S52 and personal computer under RS-232-C serial communication interface protocol. The pulse signal is then shown,recorded,saved and processed through computer software. The single-chip microcomputer AT89S52 circuit controls the collection and enlargement of the original signal and communicated with personal computer. When the single-chip microcomputer part is not connected with computer under serial communication interface,it becomes an improved portable electronic pulsometer and can be taken conveniently and show pulse number.

An universal serial bus (USB)-based high-speed real-time pulse signal detecting system is developed. The hardware and application software of the system is presented. The integrated polyvinylidene difluoride (PVDF) piezoelectric pulse sensor is used to pick-up the pulse signals of examined person and turn to the electric signal under processing. Because the signal is very weak, only after passing through the enlargement can the regular pulse profile be allowed to be obtained. The in-phase amplifier circuit is used to magnify the weak signal from the sensor. The magnified pulse signal is converted digital pulse signal through system-on-chip single-chip microcomputer C8051F130. The digitalized pulse signal is delivered to personal computer under USB interface protocol. The pulse signal is then shown, recorded, saved and processed through computer software. This inspecting system for pulse signal has many advantages, such as its structure is simple, it works steadily and reliably, its low cost, high application value and it can also realize rapid collection and storage of pulse signal.

An autopsy-confirmed case of neuro-Behcet's disease was reported with a review of the incidence, etiology, pathological changes, clinical manifestations, diagnosis, treatment and prognosis of the condition.The lesions of this case were widely distributed, involving the skin, eyes, mouth, genital organ, peripheral blood vessels, liver and central nervous system. The lesions of the central nervous system were mostly located in the cerebrum. A correct clinical diagnosis of neuro-Behcet's disease may be missed or delayed when its neurological symptoms and signs are the first or main manifestations and the other symptoms appear rather late or mild. On the basis of a definite diagnosis of Behcet's disease, the possibility of neuro-Behcet's disease should always be considered especially in patients with disturbances of the nervous system. The pathological diagnosis of neuro-Behcet's disease must be correlated with the clinical manifestasions. And in making the diagnosis, other nervous system disease, especially demyelinating disease euch as multiple sclerosis, acute disseminated ence-phalomyelitis and neuromyelitis optica should be ruled out.No autopsy-confirmed case of neuro-Behcet's disease has ever been reported in China and thie is likely to be the first case

Character Repertoires are supported by DICOM to encode Characters in different languages, in which UTF-8 and GB18030 are for Chinese characters. Each of them can replace Acquiesced Character Repertoire in Attribute Specific Character Set so that Chinese characters can be encoded in data elements. Utility programs compatible with DICOM are also required to support UTF-8 or GB 18030 for unerring representation and encoding.

Objective To observe clinical efficacy of recombinant human erythropoietin(rhu-EPO)in sepsis with anemia.Method From June 2005 to December 2006,sixty sepsis with anemia patients in the Second Affiliated Hospital of Tianjin Medical University were divided into control group(n=30)and theatment with rhu-EPO group(n=30).The exclusion criteria was:renal imufficiency patients needing blood purification,patients with hemorrhage of digestive tract,and patients who used rhu-EPO before.Patients in the rhu-EPO group were hypodermically injected with rhu-EPO at 48 hours after admission,6000 units par time,and continued every other day for two weeks.When the hemoglobin Was lower than 80 g/L,patients received red blood cell(RBC)transfusion or received other treatment decided by doctor.The data were expressed as(x±s),and were analyzed using Student's t test and Fisher's exact test with SPSS 11.5.A P valLie less than 0.05 indicated statistical significance.Results There Was no significant difference on hemoglobin between the two groups before treatment (P＞0.05).After treatment,the hemoglobin of patients in rhu-EPO group was higher than that in control group [(105.87±11.48)g/L vs.(91.23 ±19.89)g/L,P＜0.01].The units of RBC transfusions was less in patients of rhu-EPO group compared with control group[(2.0 ±0.47)U vs.(2.63±0.43)U,P＜0.01].There was no significant difference on mortality between two groups(P＞0.05).Conclusions In sepsis with anemia patients,administration of rhu-EPO every other day can increase red blood cell level and reduce RBC transfusion.

Objective To study the effects of epimedium koreanum flavones and davallia mariesil flavones on osteoporosis mice induced by retinoie acid.Methods The osteoporosis mice were induced by retinoic acid and then were fed with epimedium koreanum flavones and davallia mariesil flavones.The biochemical markers in serum were observed.Results The data showed that the blood AKP were higher in mice treated with two total flavones than mice in model group,the blood HOP/Cr,BGP,Ca2+ were lower in treated mice than model group(P＜0.01 or P＜0.05).Conclusion This study suggests that those two total flavones can effectively treat the osteoporosis mice induced by retinoic acid.

BACKGROUND:During autologous tendon grafting, the ultimate tensile strength used for suturing the end of the ligament is important for successful surgery. Improving suturing strength and increasing the number of stitches is a good choice for increasing the fixed intensity. But excess amount of stitches can produce too many thread residues, thereby affecting tendon healing.
OBJECTIVE:To investigate the essential number of suturing pins for the anterior cruciate ligament revascularization in ligament end suture fixation to reduce suturing thread exposure.
METHODS:(1) In vitro biomechanics test:12 patel ar ligament specimens were divided into two groups:the specimens were sutured with 5 or 3 stitches using Krackow suture method. The suturing thread was J&J tendon suture thread. The strength of tensile was compared between the two groups by Tensile mechanical test was conducted to compare the strength of tensile between the two groups and to explore the optimal number of stitches and suturing method. (2) Clinical application:According to the results of in vitro experiments, modified Krackow suture method was used clinical y for arthroscopic anterior cruciate ligament reconstruction in 125 cases, including 62 cases receiving 3-stitch suture, and 63 cases undergoing 5-stitch suture.
RESULTS AND CONCLUSION:The fixed strength of tensile at suture sites was over 100 N for 3-stitch double-lock suture and 110 N for 5-stitch double-lock suture. There was no significant difference in the fixed strength between the two groups, but their strength values were both over the breaking strength of suturing materials. Moreover, the fixed strength could not be reduced by suturing throughout the ligament at the first stitch. Al the 125 cases were fol owed for 6.4 months averagely, and both 3-stitch and 5-stitch suture methods achieved good outcomes. The satisfaction rate was up to 99%, and no suture breakage or loosing occurred at early and late stages. These findings suggest that, using 3-stitch double-lock suture method, a satisfactory fixed strength can be achieved with reduced thread exposure. The suturing thread can run through the ligament at the first stitch, which can reduce thread exposure but not reduce the fixed strength.

p16 tumor suppressor gene plays an important role in early diagnosis for lung cancer. The occurrence of lung cancer is closed associated with p16 gene aberrant methylation in promotor, seconed exon homozygous deletion, gene point mutation , lose of protein and mRNA expression. Also p16 is related to gene therapy and drug target therapy. This review will summarize the relationship between p16 and lung cancer.