1.Development of Plateau Emergency Medical Treatment System Mounted on Helicopter
Haifeng XIAO ; Taihu WU ; Shiwei ZHOU
Chinese Medical Equipment Journal 1993;0(05):-
Objective To develop a plateau emergency medical treatment system on the helicopter for firstaid of critical patients in the plateau at peace time and wartime.Method With the characteristics of M17B-7 helicopter considered,the components of the system were supposed to include a chest for pulmonary resuscitation and monitoring,a firstaid backpack,two thermal bags and four transport stretchers.Results The resuscitation and monitoring device was gifted with perfect ergonomic design,and the requirements for firstaid,resuscitation,rewarming and heat preservation were satisfied by the firstaid backpack and thermal bags.The system could be applied to emergency treatment of combined,multiple injuries,such as dressing,hemostasia and fixation,as well as keeping the respiratory tract unobstructed,efficient respiratory support,maintenance of vital signs and treatment of cold injury.Conclusion The plateau emergency medical treatment system on the helicopter behaves well in medical treatment and field survival ability,and thus can be allocated according to service requirements and troops' organizational system for searching and firstaid of the person in distress in the plateau.
2.Analysis of construction of tutor team and the quality of graduate student education
Zhongyu LI ; Yimou WU ; Jianhua XIAO ; Xiaoxing YOU ; Zhou ZHOU
Chinese Journal of Medical Education Research 2011;10(5):544-546
Quality is the lifeline of graduate education and the tutor team plays an important role in postgraduate training. To control the selection of tutors strictly, to implement the combination of openness and stability in tutor team, and to carry out academic exchanges actively are the keys to construct an excellent tutors staff and to ensure the quality of graduate student training.
3.Comparison of the Efficacy and Safety of Carboprost and Foley Catheter for the Expand Cervix before Hys-teroscopic Electric Resection
Xiaojuan WU ; Fangliang PENG ; Xiao ZHOU ; Hui DENG
China Pharmacy 2015;(30):4203-4204,4205
OBJECTIVE:To observe the efficacy and safety of carboprost and Foley catheter for the expand cervix before hys-teroscopic electric resection. METHODS:80 patients with hysteroscopic operation were randomly divided into research group and control group. Research group was placed inside the vagina carboprost 1 mg 30 minutes before operation;control group was placed inside the Foley catheter 12 hour before operation. The relaxation degree of the cervix,average operative time,preoperative pain, postoperative morbidity and incidence of adverse reactions in 2 groups were observed. RESULTS:There were no significant differ-ences in the relaxation degree of the cervix,postoperative morbidity and incidence of adverse reactions between 2 groups(P>0.05). The average operative time and preoperative pain in research group were significantly better than control group,the differ-ence was statistically significant(P<0.05). CONCLUSIONS:Carboprost and Foley catheter have good efficacy and safety for ex-pand cervix before hysteroscopic electric resection,however,carboprost is better than Foley catheter in terms of average operative time and preoperative pain.
4.Changes of AgNORs expression of T lymphocytes and helper T cell subsets in peripheral blood mononuclear cells from cancer patients
Xiaoming HU ; Wushu ZHAO ; Xiao CONG ; Tongliang ZHOU ; Xiaoqin WU
Chinese Journal of Laboratory Medicine 2001;0(01):-
Objective To investigate the changes of silver-stainng protein of nuclear organizer regions(AgNORs)expression of T lymphocytes and helper T (Th) cell subsets in peripheral mononuclear cells (PBMC) from cancer patients and to analyze the relationship between them.Methods AgNORs expression in T cells activated by a multiple clonal activator was examined using a special image system. After activation of PBMC with ionomycin plus PMA for 5 h, both interferon-? (IFN ?) and interleukin-4 (IL-4)producing cell frequencies were detected by enzyme-linked immunospot assay (ELISPOT). The stimulated with ionomycin plus PMA for 24 h, the IFN ?-and IL-4-production were assayed by ELISA.Resuts AgNORs expression of activated T cells in PBMC from cancer patients (n=86) and healthy persons (n=44) was (4.90?1.20) I.S% and (7.82?1.28) I.S% respectively. Th2 frequency was significantly higher and the ratio of Th1 to Th2 frequency was more lower in cancer patient group. Moreover, the IFN ? and IL-4 production in cancer patient group were changed in the way similar to Th subset frequencies. In lung cancer patients the AgNORs expression, Th1 frequency, Th1/Th2 ratio and IFN ? production were significantly decreased in metastasis or in recurrence status,AgNORs expression in cancer patients correlated with their Th1 frequencies, Th1/Th2 ratio, IFN ? production levels and Karnofsky′s estimators.Conclusions In analyzed cancer patient cases, the expression of AgNORs and the function of Th1 cell were significantly decreased and correlated.
5.Correlation with expression of HMGB1 mRNA and clinicopathological features of endometrial carcinoma
Rixue XIE ; Jiajie WU ; Ying XIE ; Meifang XIAO ; Cuixiang ZHOU
Journal of Chinese Physician 2011;13(1):41-43,48
Objective To investigate the expression of HMGB1 mRNA in endometrial carcinoma and its correlation with clinicopathological features of endometrial carcinoma. Methods Semi-quantitative RT-PCR method was used to detect the expression level of HMGB1 gene in 56 cases of endometrial carcinoma and 20 cases of normal endometrium. Results The expression of HMGB1 mRNA in endometrial carcinoma (0. 3512 ± 0. 0985 ) was significantly higher than that in normal endometrium (0. 2208 ± 0. 0170 ).There was a significant difference in the two groups( P <0. 05 ). Grouping by clinicopathological features,the expression of HMGB 1 mRNA in endometrial carcinoma had a correlation with clinical-surgical stage ( P<0. 05), metastasis of lymph nodes ( P < 0. 05), and depth of myometrial invasion ( P < 0. 05 ). Conclusion The high level of HMGB1 mRNA indicated that HMGB1 might play an essential role in the genesis, growth, invasion and metastasis of endometrial carcinoma.
6.Screening and isolation of fibrinolytic active compound from marine microorganism
Yan ZHANG ; Wenhui WU ; Peigen ZHOU ; Bin BAO ; Zhiwen XIAO
Chinese Journal of Marine Drugs 2000;0(06):-
Objective To isolate bioactive compound of enhancing fibrinolysis from secondary metabolites of marine microorganism.Methods The separation of microorganism from seawater samples,screening of producing fibrinolytic compound's strain,selection of the active strain's optimum fermentation medium and refining of active compound were done by the method of selective cultivation,measuring of compound's fibrinolytic activity and semipreparative HPLC,respectively.Results Nine hundred and thirty-six single strains from 31 samples were collected 100 meters off the coast,and cultures of the fungus(FG216) contained enhancing fibrinolytic compound.Compounds from modified Czapek medium as the fermentation medium of FG216 showed significant fibrinolytic effect.Finally,active fraction were isolated and refined from cultures of FG216.Conclusion In this paper,active compound of enhancing fibrinolysis were gained from secondary metabolites of isolated single microorganism from seawater.
7.Technical points on video assisted thoracoscopic thymectomy for thymoma accompanied by myasthenia gravis
Junxu WU ; Kaihu SHI ; Shengsong XU ; Xiao ZHOU ; Wei CAO
Chinese Journal of Primary Medicine and Pharmacy 2014;(24):3693-3694,3695
Objective To explore the value of video-assisted thoracoscopic thymectomy in the treatment of thymoma accompanied by myasthenia gravis.Methods In this study,forty-two patients who were preoperatively con-firmed to be thymoma accompanied by myasthenia gravis from 2008.1 to 2012.12 were treated using VATS,including typeⅠin 23 cases,typeⅡa in 11 cases,typeⅡb in 7 cases,and type Ⅲ in 1 case.Thymectomy and dissection of all fatty tissue anterior to the pericardium were performed in all cases.The operation time,blood loss,chest drainage time,hospital stay and outcomes were recorded and compared.Results In this group,one patient showed myasthenic crisis after surgery and recovery well after treated by ventilatory support.the patients had fewer blood loss(<35mL) , shorter operation and postoperative drainage time, and shorter postoperative hospital stay.Conclusion Extended thymectomy by VATS is safe and feasible with the advantage of less invasion,less surgical trauma and pain,lower rate of complication,and good curative effect.
8.Surveillance on endemic situation of schistosomiasis in national surveillance sites of Chongqing City in 2006
Chengguo WU ; Xingjian LUO ; Xin ZHOU ; Bangzhong XIAO ; Zhengyun SI
Chinese Journal of Schistosomiasis Control 1989;0(01):-
Objective To understand the correlative factors of impacting schistosomiasis prevalence so as to provide the scientific evidence for drawing up the control project in Three Gorges Reservoir areas.Methods The report system of schistosomiasis was set up,and the cases were investigated.The population were screened by indirect haemagglutination test(IHA),and the serum-positive people were examined with Kato-Katz technique.The livestock and plants imported from the schistosomiasis endemic areas were investigated.Results Eighty-eight floating people returning from schistosomiasis endemic areas and 107 floating persons from endemic areas were investigated,and the serum positive rates were 1.14% and 1.87%,respectively.No schistosome eggs were found in stool examinations.There was no livestock and plant imported from schistosomiasis endemic areas.The production of local inhabitants depended on mainly cattle,and the river water contact was popular.Conclusions There are infection resources of schistosomiasis imported from endemic areas,which has a potential risk of schistosomiasis prevalence.
9.Reliability and Validity of Early Father-Child Relationship Scale in China
Xiao ZHANG ; Huichang CHEN ; Guifang ZHANG ; Bofang ZHOU ; Wei WU
Chinese Journal of Clinical Psychology 1993;0(01):-
Objective: To revise the Chinese version of Father-Child Relationship Scale(FCRS) and to examine its reliability and validity. Methods: Data were collected with Child-Parent Relationship Scale based on a sample of 400 young children and their fathers,retest was given after a month,and follow-up study was carried out to 106 children for 9 months. Results: The results of Confirmatory Factor Analysis showed a good fit to the data,and the examination of its criterion-related validity,by using children's behavior problems and social competence as criterions,also indicated that both the concurrent and the predictive validities of FCRS were satisfactory. The internal consistency reliability of FCRS was satisfactory,with Cronbach ? coefficient 0.71; and the test-retest reliability was also satisfactory,with test-retest correlation coefficient 0.68(P
10.Analysis of serum AGEs and sRAGE levels in newly diagnosed patients with type 2 diabetes
Xiao CHEN ; Xiaochun ZHOU ; Weiming WU ; Yixuan JIN ; Lingling QIAN
International Journal of Traditional Chinese Medicine 2013;(1):5-7
Objective To understand the serum levels of advanced glycation end products (AGEs),soluble receptor for advanced glycation end products (sRAGE) in newly diagnosed patients with type 2 diabetes.Methods 60 patients of newly diagnosed type 2 diabetes were chosen from 2010 September to 2011 December in Department of Endocrinology Changshou Chinese medicine hospital in Jiangsu Province,and 30 healthy people were screened as control group.Various clinical and biochemical parameters were detected,using enzyme-linked immunosorbent assay for the detection of serum AGEs and sRAGE levels.Results The levels of serum AGEs in newly diagnosed type 2 diabetic patients and control group were (1379.2 ± 431.8) and (1154.5 ±326.4) pg/ml,and there were significant differences between two groups (P<0.05).The levels of serum sRAGE in newly diagnosed type 2 diabetic patients and control group were (14.6± 9.3)and (19.5 ± 8.9)ng/ml,and there were also significant differences between two groups (P<0.05).The level of serum AGEs in newly diagnosed type 2 diabetic patients was positive correlation with glycosylated hemoglobin (HbA1c),and the level of serum sRAGE was associated with low density lipoprotein cholesterol (LDL-C) negative correlation.Conclusion The level of serum AGEs increase in newly diagnosed type 2 diabetic patients,and the level of serum sRAGE decrease in newly diagnosed type 2 diabetic patients.