1.Empirical Analysis on Medical Ethics in the United Nations Peacekeeping Medical Support
Chinese Medical Ethics 2017;30(7):802-804,809
In the peacekeeping operations of the United Nations,medical personnel need to have clear legal compliance to solve the ethical problems encountered.The existing laws and regulations are impractical with a nar row cover,which can't meet the actual requirements.Based on the literatures and practical examples,this paper discussed the medical ethical problems involved in peacekeeping operations using the three-step method (empirical investigation,comparative analysis and summarization),and provided suggestions and countermeasures to the construction of medical ethics in peacekeeping medical support.
2.Homing of bone marrow hemopoietic stem cells in infarct area following myocardial infarction
Chinese Journal of Tissue Engineering Research 2009;13(27):5252-5256
BACKGROUND: Studies have shown that after bone marrow stem cell transplantation, there are juvenile cells with the episode of myocardial cells around the infarct areas, which was recognized as deriving from bone marrow stem cells.OBJECTIVE: To explore the homing situation of bone marrow stem cells by autologous mobilization around the infarct areas aftar myocardial infarction.DESIGN, TIME AND SETTING: The cytological in vitro study was performed at the China-Japan Clinical Pathology Center, Daliar Medical University from February 2005 to April 2006.MATERIALS: A total of 30 myocardial samples from the autopsy at the Department of Pathology and Forensic Medicine, Dalian Medical University between 2000 and 2005. Fifteen normal samples dyed from the mechanical injuries or craniocerebral injury,without abnormity following autopsy. Fifteen samples in the myocardial infarction group suffered from coronary atherosclerosis and coronary tube stenosis, and died within 10 days after myocardial infarction.METHODS: The autopsy was performed within 48 hours after the death and the tissues were obtained from antedor wall, lateral wall and posterior wall of the left ventricle, and made into tissue sections. We checked the expression of CD34, CD133 and transforming growth factor-β, in the normal area, infarct area and around the infarct area by immunohistochemistry.MAIN OUTCOME MEASURES: The expression of CD34, CD133 and transforming growth factor-β in different areas and the relationship between them.RESULTS: The positive expression of CD34 in infarct area was significantly stronger than that around the infarct area and in normal area (P < 0.01). The positive expression of transforming growth factor-β in infarct area was significantly stronger than that around the infarct area (P < 0.01), and the expression of transforming growth factor-β showed negative reactJon in normal area. The expression of CD34, CD133 and transforming growth factor-β, in infarct areas and around the infarct area was closely related (P < 0.01).CONCLUSION: There are the homing of bone marrow hemopoietic stem cells in infarct area and around the infarct ares after myocardial infarction. The increase in transforming growth factor-β in infarct area provides the possibility for the differentiation of the homing stem cells, the following angiogenesis and the regeneration of cardiomyocytes.
3.Clinical manifestations of osteoarthritis and the role of silent information regulation 1 in the pathogenesis of osteoarthritis
Ming LEI ; Fei YU ; Deming XIAO
Chinese Journal of Tissue Engineering Research 2017;21(12):1933-1939
BACKGROUND:Functional changes of some functional genes have been showed to trigger osteoarthritis, among which, age may be a critical one. OBJECTIVE:To summarize the clinical manifestations of osteoarthritis and the research process of silent information regulation 1 in the occurrence and development of osteoarthritis. METHODS:A computer-based retrieval was performed in the databases of CNKI, PubMed, SpringerLink, and Elsevier Science Direct using the keywords ofosteoarthritis, silent information regulation 1 and cartilagein Chinese and English, respectively. Finally 83 eligible literatures were enrolled for analysis. RESULTS AND CONCLUSION:Deacetylation modification acts on the occurrence and development of osteoarthritis by regulating the expression and biological function of various cytokines. Silent information regulation 1 cannot only regulate body metabolism, inhibit cellapoptosis, repair DNA injury, delay senescence and resist to stress, but also play important roles in the epigenetic modification, gene silencing and signal transduction. Therefore, silent information regulation 1 is involved in the age-related diseases, such as osteoarthritis, osteoporosis, diabetes and Alzheimer's disease. Furthermore, silent information regulation 1 is likely to be an important target of osteoarthritis drugs, and even reverses mechanical stress-induced cartilage injury in the early stage of osteoarthritis.
4.Primary cutaneous diffuse large B-cell lymphoma, leg type: report of a case.
Xiao-yu LU ; Chen LU ; Yu-lei YIN ; Bo YU
Chinese Journal of Pathology 2010;39(6):416-417
Antigens, CD20
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metabolism
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Antineoplastic Combined Chemotherapy Protocols
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therapeutic use
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Diagnosis, Differential
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Humans
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Leg
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Lymphoma, Follicular
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metabolism
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pathology
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Lymphoma, Large B-Cell, Diffuse
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drug therapy
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metabolism
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pathology
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Male
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Middle Aged
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Neoplasm Recurrence, Local
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Skin Neoplasms
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drug therapy
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metabolism
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pathology
6.Laparoscopic small bowel resection in the treatment of small intestinal tumors.
Lei CHEN ; Xiao-dan JIN ; Mai-yu XUN
Chinese Journal of Oncology 2010;32(10):799-780
Adenocarcinoma
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surgery
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Adenoma
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surgery
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Adult
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Aged
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Female
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Follow-Up Studies
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Gastrointestinal Stromal Tumors
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surgery
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Hemangioma
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surgery
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Humans
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Ileal Neoplasms
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surgery
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Jejunal Neoplasms
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surgery
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Laparoscopy
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methods
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Lymphoma
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surgery
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Male
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Middle Aged
8.The efficacy of losartan combined with amiodarone in cardioversion of atrial fibrillation and maintenance of sinus rhythm in patients with paroxysmal atrial fibrillation
Xuegang YU ; Yusheng XI ; Bo XIAO ; Lei ZHONG ; Xiantian LUO
Chinese Journal of Practical Internal Medicine 2001;0(02):-
Objective To investigate the efficacy of losartan combined with amiodarone in cardioversion of atrial fibrillation(AF)and maint of sinus rhythm in patients with paroxysmal AF.Methods From January 2003 to October 2005,a total of 86 consecutive patients with paroxysmal AF in 421 Hospital of PLA were randomly dividid into two group:group A(amiodarone,n=44)and.group B(amiodarone plus losartan n=42).The conversion of atrial fibrillation in 24 h,3 d and 7 d after therapy was investigated.The left atrial diameter was measured with transthoracic echocardiogram at before and after 6,12-months of treatment andyzed up to 12 months.Results The rate of cardioversion of AF is significantly higher in group A than group B at 7 d(86.36% vs 95.23%,P
9.Analysis of gastric bilirubin absorbance values and gastric pH monitoring in children with primary duodenogastric reflux.
Mi-Zu JIANG ; Xiao-Lei HUANG ; Jin-Dan YU
Chinese Journal of Pediatrics 2007;45(4):301-303
Adolescent
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Bilirubin
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metabolism
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Child
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Child, Preschool
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Duodenogastric Reflux
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metabolism
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Esophageal pH Monitoring
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Female
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Humans
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Male
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Stomach
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physiopathology
10.A discussion on the mode of multi hospitals platform
Youjun WANG ; Mingzhao XIAO ; Lei HU ; Yu LAN ; Yao WU
Chongqing Medicine 2014;(31):4142-4144,4147
Objective To discuss the informatization of multi hospitals. Methods Considering about the current situation of in‐formation construction to the First Affiliated Hospital of Chongqing Medical University, a set of solution was put forward based on the all in one card together with the two level information platform. Results Initial trials proved the feasibility of the solution. Con‐clusion The informatization of the multi hospitals contributes a lot to the source sharing between the regional hospitals, the im‐provement of hospital management and a better medical service.