2.Progresses in studies on residual cardiovascular problems in children with postoperative tetralogy of Fallot.
Chinese Journal of Pediatrics 2004;42(4):311-314
Arrhythmias, Cardiac
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etiology
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Cardiovascular Abnormalities
;
etiology
;
physiopathology
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Child
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Heart Function Tests
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Heart Septal Defects, Ventricular
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etiology
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Humans
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Postoperative Care
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Postoperative Complications
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Prognosis
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Pulmonary Valve Insufficiency
;
etiology
;
Tetralogy of Fallot
;
surgery
;
Time Factors
;
Ventricular Outflow Obstruction
;
etiology
4.Quality Standards of Chenxiang Huazhi Pills
Qiaoji GUO ; Lihe XIAO ; Ying XIONG
China Pharmacy 2001;0(07):-
OBJECTIVE:To develop a method for quality control of Chenxiang huazhi pills.METHODS:Auklandia lappa,Cyperus rotundus,Crataegus pinnati fida,Rheum palmatum,Magnoliae officinalis and Pharbitis nil were identified by TLC.HPLC was used for determination of hesperidin.RESULTS: The chromatographic spots were identified without interference of negative control.Hesperidin had a good linearity within the range of 0.024 2~0.483 2 mg?mL-1 (r=0.999 4)with average recovery of 102.5%(RSD=2.0%,n=6).CONCLUSION: This standard is used for quality control of Chenxiang huazhi pills.
5.Clinical Features of 24 Cases of Lupus Nephritis in Children
xiao-ying, ZHANG ; yan-fang, GUO
Journal of Applied Clinical Pediatrics 2006;0(21):-
180,anti-ds-DNA,anti-Sm and lower C3,are high risk factors in the development of LN.The manifestations were various and misdiagnosis at the early stage was not uncommon.
8.Association of ACTN3 gene R577X polymorphism and athletic performance of Uyghur nationality in Xinjiang.
En-Peng HE ; Xiao-Ming LIU ; Guo-Ying WANG
Chinese Journal of Applied Physiology 2014;30(2):140-141
Actinin
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genetics
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Adolescent
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Adult
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Asian Continental Ancestry Group
;
genetics
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Athletes
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Athletic Performance
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China
;
Ethnic Groups
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genetics
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Female
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Humans
;
Male
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Polymorphism, Genetic
;
Young Adult
9.Impact of lead on cytotoxicity in NRK cells and interference of calcium antagonist.
Xiao-Ting LU ; Qiu-Ying LI ; Hui-Fen GUO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(6):358-360
Calcium Channel Blockers
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pharmacology
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Cell Survival
;
drug effects
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Drug Antagonism
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Humans
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Kidney
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cytology
;
drug effects
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Lead
;
toxicity
10.Dynamical observation of the expression of TGF-?_1 and MAPK_(1/3) in the renal tubules of rats with diabetes
Bing GUO ; Ying XIAO ; Changwu WAN ; Huazhen GUI ; Guozhon ZHANG
Chinese Journal of Pathophysiology 1999;0(09):-
AIM: To observe the expression of transforming growth factor ? 1 (TGF-? 1), MAPK 1/3 and fibronectin (FN) in the development of renal tubulointerstitial disease. METHODS: Wistar male rats were randomly divided into normal control group, diabetic group of 1week, 2 weeks, 4 weeks and 8 weeks. Diabetic model was induced by peritoneal injection of streptozotocin. Immunohistochemistry was employed to detect the expression of TGF-? 1, MAPK 1/3 and FN in the kidney. TGF-? 1 protein in the renal cortex was checked by Western blot. BG, Scr and UP were analysed by biochemical methods, and the morphological changes in renal tubulointerstitium were also examined under microscopy on sections stained with HE and PAS. RESULTS: The expression of MAPK 1/3 and FN was observed, but not the expression of TGF-? 1 in normal renal tissue. Positive staining of TGF-? 1 was observed in the renal tubulo-interstitium in 1-week diabetic group and thereafter it increased in the course of diabetes. A continuous increase in the expression of MAPK 1/3 and FN was also observed in two - week diabetic rats. Chronologically the expression of TGF-? 1,MAPK 1/3 and FN and the ratio of KW/BW were positively correlative with each other in diabetic animals except one -week diabetic rats. There was also a positive correlation between MAPK 1/3 and FN in l -week diabetic rats. CONCLUSION: Our data suggest that TGF-? 1 appears in the renal tubulointerstitium in early period of diabetes and then its signal is mediated by MAPK 1/3 cascades to accelerate production of FN ,and in turn leads to renal hypertrophy and tubulointerstitial fibrosis. [