7.Concurrent chemoradiation for non-small cell lung cancer
Journal of International Oncology 2013;40(10):755-758
The standard non-surgery approach for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemoradiotherapy.Common chemotherapy regimens include EP,NP,DC and PC.New chemotherapy drugs combination and targeted therapy are still under study.The tolerances of elderly patients are declining for concurrent chemoradiotherapy,but it is not the absolute contraindication.The tolerance for hyperfraction and high dose radiotherapy is well,however,the effectiveness and long-term toxicity need to be further studied and evaluated.
8.A preliminary study on the correlation between dynamic contrast-enhanced MRI and blood stasis syndrome in breast cancer
Chinese Journal of Primary Medicine and Pharmacy 2013;20(15):2308-2310
Objective To observe the correlation of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) appearances and blood stasis syndrome in breast cancer.Methods The clinical data of 100 patients with breast cancer confirmed by operation and pathology were retrospectively reviewed.70 cases without blood stasis syndrome,30 cases with blood stasis syndrome.All the cases underwent MRI using PHILIPS Achieva 1.5T magnetic resonance scanner before surgery.Results In no blood stasis group,76.67% inhomogeneous enhancement,edge enhancement 43.33%,spiculation proportion 50.00%,which were significantly lower than those in the blood stasis group (88.57%,75.71%,83.33%).The mass ratio of the shape between the two groups had no significant difference (P > 0.05).No blood stasis group and stagnation of blood group TIC curve was mainly type Ⅳ,type Ⅲ curve ratio of no blood stasis group (3.33%) was significantly lower than blood stasis group(12.86%) (P <0.01).In blood stasis group,Emax/1 and tumor size were higher than without blood stasis syndrome group.the percentage of V per minute outflow of blood stasis group was lower than without blood stasis syndrome group.Conclusion The clinician should make a preliminary evaluation of the prognosis before operation,in order to timely and reasonably choose the method of integrated traditional Chinese and Western medicine.
9.Effect of Piribedil Combined with Madopar in the Treatment of Parkinson’ s Disease
China Pharmacist 2014;(5):806-807
Objective:To observe the clinical effect of piribedil and madopar on Parkinson's disease ( PD) . Methods:Totally 58 patients with PD were divided randomly into the treatment group (29 cases) and the control group (29 cases). Piribedil and madopar were used in the treatment group, while only madopar was applied in the control group. Therapeutic effect of both groups was evaluated by UPDRS at the end of 6 courses. Results:The decrease of UPDRS after the remedy in the treatment group was more significant than that in the control group (P<0. 05), and the total effective rate in the treatment group(89. 7%) was significantly higher than that in the control group(65. 5%)(P<0. 05). Conclusion:The clinical effect of piribedil combined with madopar on PD is superior to that of madopar alone, therefore, the combination use is a useful method in the treatment of PD with the value of popularization and applica-tion.