A kind of simple portable electronic pulsometer based on piezoelectric sensor is designed, which constituted with single-chip microcomputer AT89S51. The piezoelectric sensor is used to transform pulse beating into electrical signal. Because the signal is very weak, the regular pulse profile is only obtained after enlargement and reshaping. Three-operation-amplifier circuit is used to magnify the weak signal from sensor, and the one-order low-pass filter is used to reshape the signal to get rid of miscellaneous signals. After timing and counting by the single-chip microcomputer, the pulse number is directly shown on light-emitting diode tubes through decoding circuit. The norm time generation circuit, a single steady trigger consisted of 555 integrated circuit chip mainly, set the standard time. The single-chip microcomputer AT89S51 circuit control the enlargement and reshaping of the original signal and time trigger. This portable electronic pulsometer has many advantages, such as simple structure, steady and reliable working, direct number display, low error (

A kind of personal computer-based monitoring system with piezoelectric sensor for pulse signal is developed,which constitutes with single-chip microcomputer AT89S52 and personal computer. The integrated polyvinylidene difluoride piezoelectric pulse sensor is used to pick up the pulse signals of examined person and transfer to electric signal under processing. The weak signal from the sensor is enlarged through three-operation-amplifier circuit. The magnified pulse signal is converted digital pulse signal through ADC0809 chip and the pulse number can directly show on LED tubes through the coding circuit. At the same time the digitalized pulse signal is delivered to personal computer through serial communication interface of single-chip microcomputer AT89S52 and personal computer under RS-232-C serial communication interface protocol. The pulse signal is then shown,recorded,saved and processed through computer software. The single-chip microcomputer AT89S52 circuit controls the collection and enlargement of the original signal and communicated with personal computer. When the single-chip microcomputer part is not connected with computer under serial communication interface,it becomes an improved portable electronic pulsometer and can be taken conveniently and show pulse number.

An universal serial bus (USB)-based high-speed real-time pulse signal detecting system is developed. The hardware and application software of the system is presented. The integrated polyvinylidene difluoride (PVDF) piezoelectric pulse sensor is used to pick-up the pulse signals of examined person and turn to the electric signal under processing. Because the signal is very weak, only after passing through the enlargement can the regular pulse profile be allowed to be obtained. The in-phase amplifier circuit is used to magnify the weak signal from the sensor. The magnified pulse signal is converted digital pulse signal through system-on-chip single-chip microcomputer C8051F130. The digitalized pulse signal is delivered to personal computer under USB interface protocol. The pulse signal is then shown, recorded, saved and processed through computer software. This inspecting system for pulse signal has many advantages, such as its structure is simple, it works steadily and reliably, its low cost, high application value and it can also realize rapid collection and storage of pulse signal.

Objective To explore the correlation between the need for cognitive closure and the way of coping with the disease in patients with hepatitis B cirrhosis. Methods 217 patients with hepatitis B cirrhosis were questionnaired by the Need for Cognitive Closure Scale and the Medical Coping Style Questionnaire (Chinese version). Results The total score of need for cognitive closure in separation and conversion disorder patients was (217.65 ± 31.23) points. The scores of face, yield and avoidance in the coping style were respectively (18.87±2.49) points,(13.21±1.53) points and (17.63±2.27) points. The score of face was significantly negatively correlated with the total score and all dimension scores of the need for cognitive closure(r=-0.421,-0.387,-0.405, P<0.05);the scores of yield and avoidance were positively correlated with the total score and all dimension scores of the need for cognitive closure (r=0.343-0.432, P<0.05). There were significant difference of the way of coping with the disease in the patients with different family income, payment method, course of disease (t=-3.080-3.490, P<0.05). Multiple regression analysis showed need for cognitive closure was influencing factor of way of coping with the disease in patients with hepatitis B cirrhosis. Conclusions The level of need for cognitive closure is in the high level in patients with hepatitis B cirrhosis, and influencing the way of coping with the disease.

China ; Humans ; Liver ; surgery ; Translational Medical Research

Objective To explore the characteristics of TCM syndromes of acute coronary syndrome(ACS). Methods Clinical data of 127 ACS patients were collected and then a database was established.After that,the distribution of syndrome patterns was analyzed.Results The incidences of the following excess syndrome patterns were in a decreasing sequence:stasis syndrome,phlegm syndrome,cold syndrome and heat syndromes.The incidence of stasis syndrome was 90.5%,which was much higher than other excess syndromes.The incidences of the following deficiency syndrome patterns were in a decreasing sequence:heart-Qi deficiency syndrome,heart-Qi exhaustion syndrome,heart-yin deficiency syndrome,heart-Qi depletion syndrome,heart-kidney deficiency syndrome and heart-blood deficiency syndrome.The incidence of heart-Qi deficiency syndrome was 75.6%,which was much higher than other deficiency syndromes.The incidences of the stasis syndrome and cold syndrome in acute myocardial infarction(AMI)were higher than those in unstable angina(UA),and the incidences of heart-Qi deficiency syndrome and heart-Qi exhaustion syndrome in AMI were higher than those in UA(P

Objective To investigate the application of pathogenic examination and biomarkers detection of cerebrospinal fluid in diagnosis of intracranial infection .Methods Pathogenic and biomarkers examination were performed in cerebrospinal fluid of 49 cases with intracranial infection (infection group) and 49 cases of craniocerebral trauma but without intracranial infection (control group) .Results Adenosine deaminase activity obviously increased in tuberculous meningitis cases ,glucose levels decreased in bac‐terial meningitis and cryptococcal meningitis cases ,protein and IgA content increased in bacterial meningitis cases ,IgG levels in‐creased in bacterial meningitis and tuberculous meningitis cases ,IgM levels increased in tuberculous meningitis cases (P<0 .05) . There were no significant differences of biomarkers levels between viral meningitis cases and control group (P>0 .05) .Conclusion Combined pathogenic detection and biomarker detection of cerebrospinal fluid could be helpful for the diagnosis and treatment of intracranial infection .

Objective To investigate the incidence of postoperation constipation in patients who experienced thoracolumbar fractures screw fixation surgery.Methods A prospective cohort study was performed by investigating 99 cases who experienced thoracolumbar fractures screw fixation surgery.The patients were followed up for 1 month.The postoperative constipation relief situation was observed.Kaplan-Meier method was used to draw a plot of survival,Cox proportional hazards regression model analysis was adopted for single factor and multiple factors analysis and the prediction model of constipation relief after surgery was established.Results The trend of postoperative constipation relief of patients showed a trend of first increased and then decreased,the number of cases reached high peak on the second week,the constipation relief median time was (14.00±0.76) days.Cox multiple factors regression analysis showed that prediction function model of postoperative constipation relief was h(t)=[h0(t)]e(-0.826X1+0.353X2+0.381X3-1.404X4).Conclusions There was a high incidence of constipation in patients with thora-columbar fractures after surgery and it is difficult to relieve,clinical nurses should pay more attention to the influencing factors of postoperative constipation relief and help patients reestablish normal bowel movement as soon as possible.

Objective To observe the clinical efficacy and safety of nicergoline and aniracetam in treatment of mild and moderate cognitive dysfunction after cerebral infarction .Methods Infarction were enrolled after 70 cases of mild and moderate cognitive im-pairment patients were randomly divided into nicergoline treatment group (observation group) and aniracetam treatment group(con-trol group) ,all 35 cases .After 12 weeks of treatment were compared before and after treatment mini mental state examination (MMSE) ,activities of daily living scale(ADL) scores and transcranial Doppler(TCD) to improve the situation .Results After 12 weeks ,both groups after treatment compared with treatment MMSE score was significantly higher (P< 0 .05) ,and nicergoline group than aniracetam group(P< 0 .01);ADL score before treatment were significantly reduced (P< 0 .05) ,TCD improvement nicergoline group than aniracetam group (P<0 .01) .Conclusion Nicergoline mild and moderate cognitive dysfunction after cerebral in-farction have significant effects ,and better than aniracetam ,no significant adverse reactions occur for a wide range of clinical applications .

BACKGROUND:During autologous tendon grafting, the ultimate tensile strength used for suturing the end of the ligament is important for successful surgery. Improving suturing strength and increasing the number of stitches is a good choice for increasing the fixed intensity. But excess amount of stitches can produce too many thread residues, thereby affecting tendon healing.
OBJECTIVE:To investigate the essential number of suturing pins for the anterior cruciate ligament revascularization in ligament end suture fixation to reduce suturing thread exposure.
METHODS:(1) In vitro biomechanics test:12 patel ar ligament specimens were divided into two groups:the specimens were sutured with 5 or 3 stitches using Krackow suture method. The suturing thread was J&J tendon suture thread. The strength of tensile was compared between the two groups by Tensile mechanical test was conducted to compare the strength of tensile between the two groups and to explore the optimal number of stitches and suturing method. (2) Clinical application:According to the results of in vitro experiments, modified Krackow suture method was used clinical y for arthroscopic anterior cruciate ligament reconstruction in 125 cases, including 62 cases receiving 3-stitch suture, and 63 cases undergoing 5-stitch suture.
RESULTS AND CONCLUSION:The fixed strength of tensile at suture sites was over 100 N for 3-stitch double-lock suture and 110 N for 5-stitch double-lock suture. There was no significant difference in the fixed strength between the two groups, but their strength values were both over the breaking strength of suturing materials. Moreover, the fixed strength could not be reduced by suturing throughout the ligament at the first stitch. Al the 125 cases were fol owed for 6.4 months averagely, and both 3-stitch and 5-stitch suture methods achieved good outcomes. The satisfaction rate was up to 99%, and no suture breakage or loosing occurred at early and late stages. These findings suggest that, using 3-stitch double-lock suture method, a satisfactory fixed strength can be achieved with reduced thread exposure. The suturing thread can run through the ligament at the first stitch, which can reduce thread exposure but not reduce the fixed strength.