1.Pathogenesis of Post-stroke Reflex Sympathetic Dystrophy(review)
Chinese Journal of Rehabilitation Theory and Practice 2006;12(11):934-935
Reflex sympathetic dystrophy after stroke,also called shoulder-hand syndrome(SHS),is a common complication of stroke.It is presumed that SHS is consequence of many factors,including periphery injury,effect of sympathetic never system,neurogenic inflammation,and plasticity of central nervous system.
2.Effect of Age on Long-term Prognosis of Patients with Traumatic Brain Injury
Hao ZHANG ; Xiao-nian ZHANG ; Tong ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):332-333
ObjectiveTo investigate the effect of age on long-term prognosis of patients with traumatic brain injury (TBI).Methods102 inpatients with TBI were evaluated by following-up, using Glasgow Outcome Scale (GOS), Functioning Item of Disability Rating Scale (DRS-F) , Employability Item of Disability Rating Scale (DRS-E) and Quality of Life Index (QLI).ResultsThe average age of 102 cases was 29.7±12.5. There were no significant differences among different groups in GOS and DRS-F (P>0.05), but the level of DRS-E or QLI showed much higher in <27 years old group than those in >45 years old group (P<0.01).ConclusionThe factor of age may affect the long-term prognosis of TBI, quality of life and employability of young patients are better than elder patients.
3.Chaos theory and instructional system design of clinical teaching
Yun XIAO ; Jie XIAO ; Tong ZHANG ; Xiao XIAO
Chinese Journal of Medical Education Research 2003;0(02):-
Instructional system design is an important component of instruction. Chaos theory is used in instructional system design of clinical teaching. Application of butterfly effect, fractals and strange attractors theory enhances students’clinical capabilities and comprehensive ability to analyze and solve problems.
5.Effect of Helicobacter Pylori on Gastric Motor Function in Children with Chronic Gastrictis
tong-tong, PAN ; zhang, XU ; hui, XU ; xiao-qing, ZHOU
Journal of Applied Clinical Pediatrics 2006;0(19):-
Objective To explore the influence of helicobacter pylori(Hp) on gastric motor function in children with chronic gastrictis.Methods Forty-seven children with chronic gastrictis were classified into Hp positive and negative groups according to Hp and histology exa-mination.Each child underwent gastric emptying test of solid by using nuclide method and electrogastrogram(EGG) examination.These cases with Hp-positive acceptted these triple eradication therapy[clarithromycin 15 mg/(kg?d),amoxicillin 50 mg/(kg?d),omeprazole 0.8 mg/(kg?d)]for 2 weeks,and underwent EGG examination again after eradicating Hp.Results The half emptying time(GET_1/2)in Hp-positive gastric group were significantly longer than those in Hp-negative group(t=6.403 P
6.Relationship between Gastric Acid and Stress Ulcer Produced by Water Immersion in Young Rats
jie, ZHAO ; wen, ZHANG ; xiao-mei, TONG
Journal of Applied Clinical Pediatrics 2006;0(19):-
Objective To establish the animal model with stress ulcer(SU) and probe the relationship between the gastric mucosal injury and lasting stress time,the dynamic structural changes of pH of gastric juice.Methods Twenty-four SD young rats were randomly divided into 4 groups:control group,45 min(groupⅠ),90 min(groupⅡ),3 h(groupⅢ)groups under water immersion restraint stress(WRS).The change of gastric mucosal ulcer index(UI),pH of gastric juice were observed.Results Acute gastric mucosal damage was induced by WRS,with the WRS time prolonged,UI increased gradually and pH of gastric juice remarkably decreased in experimental rats.UI was positively rela-ted with stress time(r=0.957 P
7.Mechanisms of resistance to crizotinib in patients with transforming EML4-ALK fusion gene.
Hui-juan ZHANG ; Xiao-tong ZHANG ; Li ZHANG
Chinese Journal of Pathology 2012;41(12):862-864
Apoptosis
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drug effects
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Benzoquinones
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pharmacology
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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metabolism
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pathology
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Drug Resistance, Neoplasm
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HSP90 Heat-Shock Proteins
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antagonists & inhibitors
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Humans
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Lactams, Macrocyclic
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pharmacology
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Lung Neoplasms
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drug therapy
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metabolism
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pathology
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Mutation
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Oncogene Proteins, Fusion
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antagonists & inhibitors
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genetics
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metabolism
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Protein Kinase Inhibitors
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therapeutic use
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Pyrazoles
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therapeutic use
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Pyridines
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therapeutic use
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Triazoles
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pharmacology
9.Changes of pulmonary malondialdehyde ,glutathione and total-antioxidation content in SD rat with nitrogen dioxide exposure
Yongying XIAO ; Xirong XIA ; Yi SHI ; Maorong TONG ; Xilong ZHANG
Journal of Medical Postgraduates 2001;14(1):15-17
Objectives:To evaluate lung injury mechanism in SD rat with nitrogen dioxide(NO2) exposure. Methods:In the test-control study, pulmonary malondialdehyde(MDA),glutathione(GSH) and total-antioxidant content(T-AOC) were determined in 10 SD rats with long-term NO2 exposure,10 SD rats with short-term NO2 exposure and 10 SD rats with fresh air as control. Results: Pulmonary MDA content was increased and T-AOC was decreased significantly in SD rat exposed to NO2. Pulmonary GSH was decreased significantly in long-term NO2 exposure group as compared with short-term NO2 exposure group and control group. Conclusions: Imbalance between oxidant and antioxidant was an important mechanism in the pathogenesis of oxidizing lung injury in SD rat with NO2 exposure.
10.Strychnine nitrate' effect on intracellular potentials of Mauthner cell evoked by skin stimulation in the crucian carps.
Li-juan ZHANG ; Xue-hong TONG ; Xiao-yi LI
Chinese Journal of Applied Physiology 2005;21(2):169-230
Animals
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Carps
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physiology
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Galvanic Skin Response
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drug effects
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physiology
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Skin
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cytology
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Strychnine
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pharmacology
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Synaptic Transmission
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drug effects
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physiology