5. Optimal rotation time and pitch study of CT angiography for arterial occlusive diseases of lower limbs
Academic Journal of Second Military Medical University 2010;31(2):165-168
Objective: To identify the optimal rotation time and pitch of 64-slice spiral CT angiography for arterial occlusive diseases (AOD) of the lower limbs. Methods: We performed test-bolus in eighty patients with AOD of the lower limbs (48 with intermittent claudication and 32 with ischemic rest pain or ulceration) to confirm the aortic peak time, popliteal artery peak time and aortopopliteal bolus transit time. The patients were randomly assigned to receive two sets of scan protocols for lower limb arterial 64-slice spiral CT angiography (CTA) examination (n = 40), protocol A, with a gantry rotation time of 330 ms and a pitch of 1.0; protocol B, with a gantry rotation time of 500 ms and a pitch of 0. 85. Two experienced radiologists independently evaluated the image quality of the lower limb artery. Results: Great differences in the time to peak enhancement in the aorta (14-33 s) and popliteal arteries (20-48 s) and the aortopopliteal bolus transit time (4-24 s) were found between different AOD patients. Wide overlap of the time to peak enhancement and transit time was observed between intermittent claudication patients and ischemic rest pain or ulceration patients. The qualities of segment images were rated as excellent 63.3% (152/240), good 30.0% (72/240), and poor 30.0% (72/240) for protocol A, and excellent 98. 3% (234/238) and good 1. 7% (4/238) for protocol B, with no poor images in protocol B. Conclusion: 64-slice CTA with a gantry rotation time of 500 ms, a pitch of 0. 85, scan time>30 s, and with the contrast agent injection time maintained at 35 s, can obtain better image of lower limb arteries in patients with AOD of the lower limbs.
7.Progress on bone marrow mesenchymal stem cells transplantation for spinal cord injury.
Li WANG ; Qian WANG ; Xiao-Ming ZHANG
China Journal of Orthopaedics and Traumatology 2014;27(5):437-440
Bone marrow mesenchymal cells (BMSCs) are regarded as donor cells in cell transplantation therapies for spinal cord injury (SCI) for they have the ability of favourable proliferation and multi-directional differentiation, and are easily isolated and culturd and have less immunological reaction. It has been confirmed that subarachnoid space injection is the most ideal delivery technique of BMSCs. Bone marrow mesenchymal stem cells transplantation is safe and its reconditioning role is certain for SCI in early clinical application. The mechanism of BMSCs promoting functional recovery after SCI is probably concerned with vicarious function, nerve trophism, immunosuppression and promoting axonal regeneration by BMSCs.
Animals
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Bone Marrow Cells
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cytology
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Humans
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Mesenchymal Stem Cell Transplantation
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methods
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Mesenchymal Stromal Cells
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cytology
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Spinal Cord Injuries
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surgery