3.NOVEL ADVANCES ON PESTICIDES DEGRADATION BY MICROORGANISMS
Xiao-Hong YANG ; Jun LI ; Cheng GE ; De-Long SHEN ;
Microbiology 1992;0(06):-
Pesticides, especially chemistry pesticides with high toxicity, high residue, and difficult degradation are a kind of important environment pollutants and pesticide degradation by microorganisms is one of the powerful means to treat pesticide pollution. Many researchers conducted lots of studies on it. Types of pesticide degraders, construction of genetically engineered microorganisms, degrading mechanisms, degradation characteristics, influencing factors, applying effect and so on were summarized in this article. The research trend of degradation of pesticides by microorganisms and problems to be solved were also put forward.
4.Effects of standardized three-stage rehabilitation treatment on neurological deficit scores and ADL performance of ischemic stroke patients
Yu-Long BAI ; Yong-Shan HU ; Wen-Hua CHEN ; Xiao-Bing WANG ; An-Long CHENG ; Cong-Yu JIANG ; Yi WU ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(04):-
Objective To observe the effects of standardized three stage rehabilitation treatment on the neu- rological deficit scores (NDS) and ADL performance of ischemic stroke patients.Methods A total of 164 ischemic stroke patients were recruited and randomly divided into a rehabilitation group and a control group.The neurological function and ADL performance of the patients were assessed by using NDS and Modified Barthcl Index (MBI) at the admission,at the end of 1st,3rd and 6th months post stroke.Results No significant differences were found be- tween the rehabilitative and the control groups with regard to NDS and MBI at admission.The NDS demonstrated a decreasing tendency,while the MBI score an increasing tendency in both groups.In the control group,significant difference of NDS was found between admission and the end of 1st month as well as between the end of the 1 st and the 3rd months.In rehabilitation group,significant difference was revealed between all the time points with regard to NDS and MBI scores.At the end of the 1st,3rd and 6th months,the MBI scores of the rehabilitation group were signifi- cantly higher than those of the control group,indicating that the ADL performance of those treated with standardized three-stage rehabilitation protocol was improved quicker than those without the protocol.Conclusion Standardized three-stage rehabilitation treatment could improve the neurological function and ADL performance of the ischemic stroke patients.
5.Advances in diabetic animal models and its application in the traditional Chinese medicine research.
Long CHENG ; Zhu-fang SHEN ; Gui-bo SUN ; Xiao-bo SUN
Acta Pharmaceutica Sinica 2015;50(8):951-958
The high and continuing soaring incidence of diabetes may become a huge obstacle to China's development. The antidiabetic drug development is one way to solve the problem. Animal model is a powerful tool for drug development. This paper compares and analyzes the three kinds of animal models for antidiabetic drug development in replicating principle, methods and characteristic, then summarized the application in the research of traditional Chinese medicine. At the same time, the analysis of the market, application and clinical advantages of hypoglycemic medicine from traditional Chinese medicine, is given in this paper, based on the literature analysis. From the point of the clinic advantage embodiment and new drug development, this paper will provide advisory and assistance support for the anti-diabetic fighting with traditional Chinese medicine.
Animals
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China
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Diabetes Mellitus
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drug therapy
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Disease Models, Animal
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Drug Discovery
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Humans
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Hypoglycemic Agents
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Medicine, Chinese Traditional
7.Clinjcal Study Chemotherapeutic Renal Failure Treated with Wuling Powder with Additives
Jianghua CHENG ; Hao LONG ; Dehui ZHAO ; Xiao WANG ; Jiali ZHU ; Liping ZHU ; Zhaoming HUANG
Journal of Traditional Chinese Medicine 1993;0(01):-
24 cases of renal failure induced by chemotherapy were treated with Wuling powder plus additives.Theresult of clinical amelioration was 87.5%.with a to-tal effective yielded marked actions of promoting ap-petite in animals,lowering serum urea nitrogen,cre-atinine,2 microglobulin.It also decreased the inhibi-tion of PDD on the enzyme activity of renal Na~+—K~+ATP.Microscopic exam revealed the pathological le-sion of kidney to be milder in the tested group.
8.Case Report:White-spot disease of Chinese soft-shelled turtles (Trionyx sinens) caused by Paecilomyces lilacinus
LI XIAO-LIANG ; ZHANG CHU-LONG ; FANG WEI-HUAN ; LIN FU-CHENG
Journal of Zhejiang University. Science. B 2008;9(7):578-581
Chinese soft-shelled turtles (Trionyx sinens) in culture farms using an artificial warming system in Zhejiang, China,often show typical signs of white-spot disease such as white spots on their bodies, skin lesions, anorexia and eventually death. The sick turtles were mostly 5~80 g in weight. A suspected fungai pathogen was isolated from the sick turtles and verified as Pae-cilomyces lilacinus by sequence analysis of the internal transcribed spacer (ITS) of its ribosomal DNA (rDNA). Detailed mor-phological examinations were also conducted to confirm the white-spot disease.
9.Dynamic Changes of Serum Lipids and Relationship with Body Mass Index after Fat Diets in Obese Children and Adolescents
xue-mei, HUANG ; gun-wen, LONG ; ying-xia, DENG ; yun-wu, XIAO ; hui, JIAN ; hong, XIA ; fang-gun, CHENG ; hui, LONG ; zhe, ZHU
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To explore dynamic response of serum lipids and relationship with body mass index(BMI)after fat meal in obese children and adolescents. Methods The subjects were 31 obese children and adolescents (BMI ≥ 25 kg/m2) and 30 controls (BMI