This paper makes a statistical analysis on the acupuncture treatment of dementia recorded in 93 ancient books. The statistics show that the common acupoints are Shenmen ( HT 7), Shaoshang ( LU 11 ),Dazhong ( KI4), Yinbai ( SP 1 ), Houxi ( SI 3 ), Xinshu (BL 15), Yongquan (KI 1), Jiuwei (CV 15) and Baihui (GV 20); the common meridians are the Heart Meridian, Bladder Meridian and Kidney Meridian; the common areas are palm, medial side of leg, upper back and head; the acupoints of the heart meridian are frequently used, especially those in the distal end;heavy moxibustion functions to open orifices and needling to regulate qi.

Information of the acupuncture treatment ofdepression in 93 ancient books has been made statistics with computer Results showed that Heart Meridian, Pericardium Meridian, Bladder Meridian, Governor Vessel,Conception Vessel, Spleen Meridian and Stomach Meridian have been used frequently; as to areas, the medi al aspect of upper limbs, head and face, medial aspect of legs, upper back, chest and abdomen have been mostly selected; as to treatment methods, needling,moxibustion and blood-letting therapies have been utilized.

The data concerning the treatment of diarrhea by acupuncture in 62 ancient books are computerized and thus show that the ancient acupuncturists primarily used the acupoints of the conception vessel, stomach meridian, bladder meridian, and the foot yin meridians.As to the location, the acupoints on the abdomen, back,exterior side of leg and the hands and feet are used. The common techniques are moxibustion, hot compression,needling, blood letting, navel application and so on.

The information concerning dormant papule in 93 ancient medical books is statistically computerized and shows that there are totally 29 items of information and 25 acupoints (55 times in frequency) in connection with dormant papule. The commonly used acupoints are Quchi (LI 11), Jianyu (LI 15), Tianjing (TE 10), etc, which are around joints, on the upper body, on the lateral aspect or on the ends of the limbs. The commonly used meridians are Large Intestine Meridian, Pericardium Meridian,Triple Energizer Meridian, and Gallbladder Meridian. The commonly used parts are the lateral aspect of arm, the dorsum of hand, the external aspect of leg, the medial aspect of arm, and the palm.

This paper makes a statistical analysis on the acupuncture treatment of stranguria recorded in 62 ancient books with computer. The statistics show that the frequently treated meridians are Conception Vessel,three yin meridians of foot, and Bladder Meridian; the commonly treated areas are lower abdomen, midial aspects of legs, and lower back; the commonly used techniques are moxibustion, and needling.

The information concerning the treatment of Bi condition in 93 ancient medical books has been statistically analyzed through computer. The results showed that there were a total of 149 items of literature and 102 acupoints (276 times in frequency) in association with Bi condition. The common acupoints are Hegu (LI 4), Zusanli (ST 36), Fengshi (GB 31), diseased foci, Quchi (LI 11), Weizhong (BL 40), Yanglingquan (GB 34), Yangfu (GB 38), et al. The common meridians are Gallbladder Meridian,Bladder Meridian, Large Intestine Meridian, Stomach Meridian, Lung Meridian, Liver Meridian and Triple Energizer Meridian. The common parts are the lateral aspect of leg, arm, and foot, the medial aspect of foot, the lateral aspect of hand, the medial aspect of arm, and head. The common acupuncture techniques and their frequencies are moxibustion (54), needling (9), blood-letting (9), fire needling (2), ironing (2) and compression (1). Statistical analysis on the above information showed in the ancient times in treating Bi condition with acupuncture, selecting acupoints are according to meridian distribution, the body parts and syndrome differentiation.

Objective To explore the effect of different doses of tirofiban for PCI, myocardial injury and arterial flow conditions.Methods 70 patients undergoing PCI elevation acute myocardial infarction, were randomly and equally divided into the observation group and the control group.The control group of patients before PCI given haplotype character loading dose of tirofiban, the observation group were given a double load before PCI tirofiban.Recording and analyzing two groups of patients cTnI (cardiac troponin I), 90 minST section down percentage circumstances.Results The patients after 6h, 12h, 24hcTnI contents were (2.11 ±0.50,3.50 ±1.64,3.28 ±1.15) ng/mL was significantly lower than the control group (4.09 ± 1.13,9.48 ±2.61,5.79 ±1.26) ng/mL, and the difference was significant(P<0.05); the observation group were CTFC, 90 min fall within ST respectively was significantly better than the control group ( P<0.05 ) .Conclusion Preoperative use of double loading dose of tirofiban can effectively improve the blood flow after PCI,, and reduce the incidence of myocardial injury and postoperative cardiovascular events.

BACKGROUND: Basic fibroblast growth factor (bFGF) can accelerate the bone marrow mesenchymai stem cells (BMSCs) proliferation and differentiation into nerve cells, which is considered as a mitogen of glial cells.OBJECTIVE: To investigate the survival and differentiation of bFGF gene modified BMSCs transplanted on rat models of cerebral ischemia by double immunofluorescence staining, and to study the differentiation trend of BMSCs into neuron-like cells and glial cells.DESIGN, TIME AND SETTING: The randomized control animal experiment was completed in the central laboratory of Experimental Animal Center of Central South University from July 2005 to March 2006.MATERIAL: Fifty Sprague-Dawley rats were divided into 4 groups at random: sham operation group (n=10), cerebral ischemia-reperfusion injury group (n=10), BMSCs group (n=i5) and bFGF modified BMSCs group (n=15). METHODS: Except sham operation group, rats in the other three groups were prepared for local cerebral ischemia-reperfusion models. Then BMSCs or bFGF modified BMSCs were intravenously transplanted into cerebral ischemic rats, and the same volume of DMEM were injected in the cerebral ischemia-reperfusion injury group. MAIN OUTCOME MEASURES: Survival rate and differentiation of grafted cells were observed by 5-bromo-2-deoxyuridine (BrdU)-NeuN, and BrdU-glial fibrillary acidic protein (GFAP) double immunofluorescence staining; the neurological scores and infarction volumes in each group. RESULTS: At 7 days after implantation, the number of BrdU/NeuN-positive cells and BrdU-GFAP-positive cells in the bFGF modified BMSCs group was higher than those on the BMSCs group (P < 0.05), but there were no significant differences in the co-expression cells by double immunofluorescence staining between the two groups (P > 0.05). At 7 days following reperfusion, neural function of cerebral ischemia rats were improved and infarction volume was reduced in both BMSCs group and the bFGF modified BMSCs group, and bFGF modified BMSCs group was superior to BMSCs group. CONCLUSION: BMSCs modified by bFGF can survive in cerebral ischemic region and differentiate into neuron and glial cells, which are more proper for repairing nerves.

Adolescent ; Diagnosis, Differential ; Humans ; Male ; Sturge-Weber Syndrome ; pathology

OBJECTIVETo compare the differences in the clinical efficacy on Alzheimer's disease between acupuncture and medicine.

METHODSOne hundred and forty-one patients were randomized into an acupuncture group (72 cases) and a medicine group (69 cases). In the acupuncture group, the needling technique for benefiting qi, promoting blood circulation, regulating mind and improving intelligence was used at Shenting (GV 24), Baihui (GV 20), Fengchi (GB 20), Wangu (GB 12), Danzhong (CV 17), Zhangwan (CV 12), Qihai (CV 6), Xuehai (SP 10) and Zusanli (ST 36). The supplementary acupoints were selected according to the symptoms and physical signs. Acupuncture was given once a day and 6 treatments were required for a week. In the medicine group, the choline sterase inhibitor, donepezil (aricept) was prescribed for oral administration, 1 tablet (5 mg) each time, once every night. Four weeks later, the dose was increased to 2 tablets (10 mg) each time. In the two groups, the treatment of 4 weeks made one session and 4 sessions were required. The changes of scores before and after treatment in the minimum mental state examination (MMSE), the activity of daily living scale (ADL), Alzheimer's disease assessment scale-cognition (ADAS-cog) and the digit span (DS) were observed.

RESULTSAfter treatment, scores of MMSE and DS were increased as compared with those before treatment (both P < 0.05) and scores of ADL and ADAS-cog were reduced as compared with those before treatment. The score differences in MMSE, ADL, ADAS-cog and DS before and after treatment were significant in the two groups (all P < 0.01).

CONCLUSIONThe needling technique for benefiting qi, promoting blood circulation, regulating mind and improving intelligence significantly improves the overall function, cognition and activity of daily life in the patients of Alzheimer's disease and the efficacy is better than donepezil.

Activities of Daily Living ; Acupuncture Points ; Acupuncture Therapy ; Aged ; Aged, 80 and over ; Alzheimer Disease ; psychology ; therapy ; Cognition ; Female ; Humans ; Male ; Middle Aged ; Treatment Outcome