1.Surgical management for traumatic recurrent dislocation of the peroneal tendons
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Objective To study surgical techniques for the treatment of traumatic recurrent dislocation of the peroneal tendons. Methods A total of 21 cases of traumatic dislocation of the peroneal tendons from 1986 to 2003 were treated with the Watson-Jones operation. Results A follow-up series was carried out in 15 cases for 1~15 years (mean, 4.9 years). Recurrence of dislocation occurred in 1 case, as a result of trauma, while the rest of 14 cases had returned to normal sports or competitions. Conclusions The Watson-Jones operation for recurrent dislocation is technically feasible and minimally invasive, offering satisfactory outcomes.
2.Clinical Comparative Study on 1470nm Diode Laser Vaporization Prostatectomy and Bipolar Transurethral Plasmakinetic Prostatectomy Used in the Treatment of Benign Prostatic Hyperplasia
Jian XU ; Yunfei HU ; Xiao WANG
Journal of Medical Research 2017;46(4):123-127
Objective To compare the therapeutic effects of 1470nm diode laser vaporization prostatectomy and bipolar transurethral plasmakinetic prostatectomy (TUPKP) for treatment of benign prostatic hyperplasia (BPH).Methods From June 2015-February 2016 a total of 95 patients diagnosed with BPH were randomly divided into 2 group:52 patients were treated with TUPKP while 43 patients with 1470 diode laser.All patients were followed up with mean operative time,intra-operative blood loss,postoperative hospital stay,postoperative catheterization time,postoperative complications,international prostate symptom score (IPSS),score of life quality (QoL),maximum flow rate (Qmax),post-void residual (PVR) before and after surgery.Results Compared with data of preoperation,postoperative IPSS,QoL,Qmax,PVR in 6 months revealed significant improvement in both of two groups.IPSS of TUPKP group and 1470 group respectively dropped to 6.3 ± 2.6 and 6.7 ± 2.4.In TUPKP group,PVR reduced to 23.1 ± 20.9ml and in 1470 group decreased to 24.3 ± 19.9ml.While Qmax increased to 18.5 ± 3.1 ml/s and 18.7 ± 2.8ml/s respectively in TUPKP and 1470 group.In TUPKP group,operation time were 60.1 ± 14.9min,significantly less than that in 1470 group of 69.3 ± 12.9min (P < 0.05).Compared with catheterization time in 1470 group of 33.9 ± 9.4h,the time in TUPKP group of 73.9 ± 37.6h was shorter with significant difference (P < 0.05).While Curative effect of two groups of showed no significant difference (P > 0.05).Conclusion The clinical curative effect of two operation methods for patients with BPH showed no significant difference.1470 group had longer operation time,while TUPKP group had less intraoperative bleeding and postoperative recovery.
3.Traumatic Dislocation of the Peroneal Tendons
Jian XIAO ; Yuelin HU ; Yingfang AO
Chinese Journal of Sports Medicine 2003;0(05):-
Objective To study the injury mechanism, diagnosis and therapy of traumatic dislocation of the peroneal tendons. Methods 18 cases with traumatic dislocation of the peroneal tendons were operated in our institute from 1986 to 2000. The mechanism of injury and clinical findings were investigated. 2 cases with acute dislocation were operated by suturing the peroneal retinaculum directly. 16 cases with recurrent dislocation were treated with Watson-Jones operation. Results 10 cases with recurrent dislocation were follow-up from 1 year to 15 years with an average of 6.2 years. Only one recurrence due to ankle sprain was found and the other 9 cases had no more dislocation and returned to sports without symptom.Conclusion Traumatic dislocation of the peroneal tendons can be caused by the injury of ankle joint in three positions:dorsiflexsion and eversion, dorsiflexsion and inversion, plantflexsion and inversion. Anti-resistant test of dorsiflexsion and eversion may help diagnosis. Watson-Jones operation has the advantages of simple to apply, minor trauma and sound clinical outcome.
5.Acupuncture clinical trials published in high impact factor journals.
Min HU ; Jian-Ping LIU ; Xiao-Ke WU
Chinese Journal of Integrated Traditional and Western Medicine 2014;34(12):1413-1416
Acupuncture clinical trials are designed to provide reliable evidence of clinical efficacy, and SCI papers is one of the high-quality clinical efficacy of acupuncture research. To analyze these papers published in high impact factor journals on acupuncture clinical trials, we can study clinical trials from design to implementation, the efficacy of prevention and cure, combined with international standard practices to evaluate the effectiveness and safety of acupuncture. That is the core of acupuncture clinical trials, as well as a prerequisite for outstanding academic output. A scientific and complete acupuncture clinical trial should be topically novel, designed innovative, logically clear, linguistically refining, and the most important point lies in a great discovery and solving the pragmatic problem. All of these are critical points of papers to be published in high impact factor journal, and directly affect international evaluation and promotion of acupuncture.
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7.The Arthroscopy Treatment of Intra-articular Osteoid Osteoma: 7 Cases Report
Zhenming HE ; Guoqing CUI ; Gongzhou LIN ; Jian XIAO ; Yuelin HU
Chinese Journal of Sports Medicine 2010;(1):62-64
Objective To summarize the clinical experience of diagnosis and arthroscopic treatment of intratment of intra ular osteoid osteoma.Methods Seven patients(average 22.4 years old with range from 11~32 years)with intra-articular Osteoid osteoma who underwent arthroscopy treatment from March 2006 to June 2009 were studied respectively.Thin-section CT scanning was used to confirm diagnosis and determine surgery location.Results The time span between the appearance of clinical symptoms and confirmed diagnosis was 26.0 months on average(range from 18 to 36 months).At a mean 19-month follow-up,all patients showed significant improvements including VAS decrease,no recurrence,pain relief and normal range of motion.Conclusion The atypical clinical features and radiographic findings of osetoid osteoma might lead to the delayed diagnosis.Using arthroscopy to remove intro-articular osteoid ostema was a safe and effective way.
8.Protective effect of modified acidic fibroblast growth factor on renal ischemia/reperfusion injury of rats
Wenjuan HU ; Juen HUANG ; Xiaokun LI ; Jian XIAO
Chinese Pharmacological Bulletin 1987;0(02):-
Aim To study the protective effect of modified acidic fibroblast growth factor (MaFGF) on renal ischemia/reperfusion injury of rats. Methods 32 Wistar rats were divided randomly into four groups;false operative control group, model control group, 8 ?g?kg-1 of MaFGF and 16 ?g?kg-1 of MaFGF groups with 8 animals in each group. Renal pathological changes were observed by light and electron microscope. Results As shown in pathology, compared with model control group, MaFGF group could significantly reduce edema, number of leukocytes appearing in the interstitium ,distention and destroy of renal tissues. Under EM, the ultrostructure(including microvilli, mitochondria and lysosomes etc.) of the tubular epithelial cells of MaFGF groups appeared lighter in injuries or even near normal. Conclusion MaFGF has a role in attenuation of renal damage or failure after ischemia-reperfusion injury of the kidney.
9.Expression of interleukin-17 and retinoid-related orphan nuclear receptor gamma t in cornea of experimental keratomycosis
Zong-sheng, ZENG ; Xiao-li, HAN ; Jian-zhang, HU
Chinese Journal of Experimental Ophthalmology 2013;(7):653-658
Background In the past few decades,the balance of Th1/Th2 is often used to explain the immune mechanisms of fungal infection and fungal disease.More recently,a novel subset of CD4+ effector Th cells has been found to participate in anti-fungal infection response.However,whether Th17 is involved in the immune response in fungal keratitis is unclear up to now.Objective Present study was to investigate the expression change of Th17 type cytokine and its specific transcription factor,retinoid-related orphan nuclear receptor gamma t (RORγt),in the cornea of Fusarium solani keratitis.Methods Ninety-six clean BALB/c mice were divided into Fusarium solani keratitis model group and control group by randomized digital table.Fusarium solani keratitis models were established by epikeratophakia-assisted corneal epithelial erasion and interlayerly injection of 5 μl (1 × 106 CFU/ml) Fusarium solani solution in the right eyes,and the equal volume of PBS was injected in the same way in the control group.10% KOH wet film was used to examine the fungal hyphea and funga strain was identified by inoculation.The corneas were examined under the slit lamp microscope 1 day,3,5,7 days after modeling and the inflammatory response was scored based on the criteria of Wu and Hu.The histopathological examination of corneas was performed in the time points above.Real time fluorescence quantitative PCR was used to detect the expression levels of interleukin-17 (IL-17) mRNA and RORγt mRNA in the corneas.The expression of IL-17 protein in the corneas was detected by ELISA.The use and raise of the mice followed the Statement of Association for Research in Vision and Ophthalmology.Results The inflammatory scores were 3.2±0.8,6.6± 1.1,9.4± 1.1 and 6.8±0.8 in 1 day,3,5,7 days after modeling,showing a significant difference among them (F =89.786,P =0.010).The inflammatory scores were higher in the third and seventh day than that in the first day (P<0.05),but they were significantly lower than that in the fifth day (P<0.05).The infiltration of inflammatory cells showed a coincident tendency with the score.The expressing levels of IL-17 mRNA (2-ΔΔCt) in the corneas were 4.12±0.73,20.72±1.81 and 14.16±1.88 in 3,5,7 days after modeling,with statistically significant differences in comparison with those in the control group (P<0.01),and the expression level was significantly higher in the fifth day than those in the first,third and seventh day in the model group(P<0.01).The expression levels of IL-17 protein (ng/g) were significantly increased 1 day,3,5,7 days in the model group compared with the control group (P<0.01).A similar change was found in the expression of RORγt mRNA to that of IL-17 mRNA.Conclusions Expressions of IL-17 and its transcription factor RORγt upregulate in the fungal keratitis and has an association with inflammatory degree,which suggests that Th17 subset may play an important role in the immune responses of fungal keratitis.
10.Comparative study of arthroscopic reconstruction of anterior crucial ligament with autograft and aliograft of bone-patellar tendon-bone
Qiu-Jian ZHENG ; Ming CHEN ; Bin HU ; Dan XIAO ;
Chinese Journal of Trauma 1993;0(06):-
Objective To compare the effect of allograft and autograft of bone-patellar tendon- bone (B-PT-B) under arthroscopy in reconstruction of anterior cruciate ligament (ACL).Methods The injured ACL was reconstructed under arthroscopy by using autograft of B-PT-B in 30 cases and al- lograft of B-PT-B in 28 cases from January 2000 to August 2003.After over twelve months follow up,a comparison was done on rehabilitation of quadriceps femoris,knee stability,the Lysholm's score of knee and the enlargement of tunnel in both groups.Results Both groups obtained marked improvement of knee stability and symptoms after operation.But in the early time,the rehabilitation of quadriceps femoris in the ailograft group is faster than that in the autograft group.The rehabilitation of quadriceps femoris, knee stability and the Lysholm's score of knee were similar at 12th month (P>0.05).There could be seen enlargement of tunnel in both groups,with more in the allograft group (P>0.05).Conclusion For arthroscopic reconstruction of anterior crucial ligament (ACL),allograft of B-PT-B is good substitute, for it is characterized by effectiveness,convenience and minor side effect.