1.Clinical observation on the effect of resection of eyelid tumor and stageⅠ recovery
International Eye Science 2014;(8):1535-1536
AIM: To investigate clinical effects of local resection of eyelid tumors and pathological examination or frozen section examination as well as the stage I recovery.
METHODS: For all 92 cases 92 eyes of eyelid tumor patients who underwent local resection, reconstruction in stage Ⅰ and routine pathological examination ( 37 cases of suspected malignant tumors using frozen section examination. If it was malignant, excision by Moths surgery) . Using free palate mucosa autograft in stage I or reconstruction by Hughes surgery combined with eye flaps repaired eyelid defects.
RESULTS: The postoperative pathological diagnosis:52 cases were benign tumors, and 40 cases malignant tumors. All cases of eye flaps and hard palate mucosa grafts were survived. Followed up for more than 6mo, no tumor were recurred. The appearance and function of eyelid were satisfactory.
CONCLUSION: In this group of cases, nearly half of eyelid tumors are malignant tumors. It should be treated and operated as early as possible. For suspected malignant tumors, we use frozen section examination to confirm its properties in order to excision cleanly in stageⅠ, reducing the recurrence and metastasis. According to the eyelid defect after resection, we could do repair operation in stage Ⅰ. The inner larger defect is repaired by using hard palate mucosa transplantation or Hughes surgery. The outer layer of the eyelid defect is repaired by using eye flap glide, the free flap, the kite flap, the simple suture, etc. It should be careful when using the hard palate mucosa transplantation in the upper eyelid defect.
2.Treatment outcome of allogeneic hematopoietic stem cell transplantation in patients with hematologic malignancies not in remission.
Hai-Yan BAO ; Xiao-Jin WU ; Xiao MA
Chinese Journal of Oncology 2012;34(2):156-157
Adolescent
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Adult
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Disease-Free Survival
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Female
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Graft vs Host Disease
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etiology
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prevention & control
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Hematologic Neoplasms
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therapy
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Hematopoietic Stem Cell Transplantation
;
adverse effects
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Humans
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive
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therapy
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Leukemia, Myeloid, Acute
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therapy
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Lymphocyte Transfusion
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Lymphoma, Non-Hodgkin
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therapy
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Male
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Middle Aged
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Recurrence
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Survival Rate
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Transplantation, Homologous
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Young Adult
3.Application of high frequency electrical capsulotomy in maturation period cataract surgery
Wen-Hai, WANG ; Xiao-Yan, WU ; Jian-Lan, ZHANG
International Eye Science 2016;16(10):1927-1928
AIM: To explore the clinical effects of high frequency electrical capsulotomy in maturation period cataract surgery.
●METHODS: A total of 68 cases of maturation period cataract were selected and underwent the surgery of continuous circular capsulorhexis using the high frequency electrical capsulotomy.
●RESULTS: The success rate was 91% in 68 cases with the high frequency electrical capsulotomy.
● CONCLUSION: The high frequency electrical capsulotomy in maturation period cataract surgery has significant advantages and brilliant clinical values.
4.Mid-term follow-ups of hydroxyapatite extensively-coated femoral prosthesis for elderly patients
Yun-Li ZHU ; Hai-Shan WU ; Xiao-Hua LI ;
Chinese Journal of Orthopaedic Trauma 2004;0(08):-
Objective To evaluate the effects of hydroxyapatite (HA) extensively-coated prosthesis on elderly patients undergoing hip arthroplasty.Methods From February 1997 to May 1999,96 patients Were treated with hydroxyapatite (HA) coated prosthesis and followed up for their hip arthroplasty.Their results were studied clinically and roentgengraphically to evaluate chiefly their Harris scores,complications and thigh pain.The survival of prosthesis was evaluated according to Kaplan-Meier methods.Results The 60 cases were followed up for eight years on average(range,sevon to nine years).Their mean Harris scores were improved from 42 preoperatively to 90 postoperatively.Fifty-eihgt cases felt no pain at their hip,but two did at their thigh.No radiolucent lines were observed.All the prostheses achieved bony stabilization and remolding.Conclusions HA coated prosthesis can achieve fine fixation,because it helps bone conduction,resists axial force and torsion,and reduces operative risks.
5.Cloning,High Level Expression and Purification of Human Survivin
Hai LI ; Yu PENG ; Xiao-Tian LI ; Wen-Yan WU ;
China Biotechnology 2006;0(10):-
Survivin is a protein that inhibits apoptosis and regulates cell division.The cDNA sequence of survivin was amplified by RT-PCR and sub-cloned into the prokaryotic expression vector pET-21b(+),followed by transformation into E.coli strain BL21(DE3) and induction with IPTG.The recombinant survivin protein fusing with 6?His tag was expressed in E.coli in the form of inclusion body at the expression level over 60% of the total cell protein.Results of Western blotting showed that recombinant survivin reacted specifically with anti-human survivin antibody.After gel filtration,the recombinant protein reached the purity over 95%,which facilitate the study of diagnosing and inhibitor agents targeting survivin.
6.Hypertrophic cardiomyopathy with right aortic arch, right descending aorta, and Kommerell's diverticulum: a case report.
Xiao-han FAN ; Hai-ying WU ; Si-yong TENG
Chinese Journal of Cardiology 2009;37(8):755-756
Cardiomyopathies
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complications
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Diverticulum
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complications
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Hematoma
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complications
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Humans
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Male
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Middle Aged
7.Meningeal hemangiopericytoma: a clinicopathologic study of 17 cases.
Hai-Bo WU ; Hai-Yan WENG ; Min DING ; Ping GU ; Xiao-Qiu WANG ; Wen ZHONG
Chinese Journal of Pathology 2011;40(4):251-252
Adult
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Aged
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Antigens, CD34
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metabolism
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Chondrosarcoma, Mesenchymal
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metabolism
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pathology
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Diagnosis, Differential
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Female
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Follow-Up Studies
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Hemangiopericytoma
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metabolism
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pathology
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radiotherapy
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surgery
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Humans
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Male
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Meningeal Neoplasms
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metabolism
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pathology
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radiotherapy
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surgery
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Meningioma
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metabolism
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pathology
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Middle Aged
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Neoplasm Recurrence, Local
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Proto-Oncogene Proteins c-bcl-2
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metabolism
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Solitary Fibrous Tumors
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metabolism
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pathology
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Vimentin
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metabolism
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Young Adult
8.Gastric adenocarcinoma associated with myelolipoma of parietal pleura: a case report.
Dong-sheng ZHANG ; Dong-hai LI ; Hai-xia BI ; Xiao-feng WU
Chinese Journal of Pathology 2006;35(7):437-437
Adenocarcinoma
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pathology
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surgery
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Biopsy
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Diagnosis, Differential
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Gastric Fundus
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pathology
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surgery
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Humans
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Male
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Middle Aged
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Myelolipoma
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pathology
;
surgery
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Neoplasms, Multiple Primary
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pathology
;
surgery
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Pleural Neoplasms
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pathology
;
surgery
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Stomach Neoplasms
;
pathology
;
surgery
10.Effect of docetaxel-loaded lipid microbubbles combined with ultrasound targeted microbubbles destruction on microvessel of rabbit VX2 liver tumor models
Juan KANG ; Xiao-ling WU ; Yong ZHANG ; Hai-tao RAN ; Zhi-gang WANG
Chinese Journal of Interventional Imaging and Therapy 2011;08(5):431-434
ObjectiveTo observe the inhibition effect of docetaxel-loaded lipid microbubbles (DLLM) combined with ultrasound targeted microbubbles destruction (UTMD) on microvessel in rabbit VX2 liver tumor models.MethodsSixty rabbits were randomly divided into 6 groups (n= 10),i.e.Doc group (used docetaxel only),DLLM group (used docetaxel-loaded lipid microbubbles),Doc+US group (used docetaxel combined with ultrasound positioning irradiation),PLM+US group (used microbubbles combined with ultrasound positioning irradiation),DLLM+US group (used docetaxel-loaded lipid microbubbles combined with ultrasound positioning irradiation) and control group.The expression of CD34 and VEGF and microvessel density (MVD) were compared among different groups.ResultsAfter treatment,the expression of CD34 in DLLM+US group was lower,the MVD of DLLM+US group was markedly lower than that of the other groups (P<0.01),while the expression of VEGF in this group was the lowest among all 6 groups (P< 0.01).ConclusionDLLM combined with UTMD can inhibit the generation of microvessels in rabbit VX2 liver tumor,thus inhibit the growth of the tumor.