1.Analysis and discussion about current development of relevant studies on "traditional Chinese medicine components".
China Journal of Chinese Materia Medica 2014;39(2):171-174
As traditional Chinese medicine components have become a hotspot in the field of traditional Chinese medicine study, they have followed a development trend of diversity and false identification. In studies on a new modem product, we shall encourage the diversified development mode, but avoid the false concept identification of traditional Chinese medicine components. In this paper, by analyzing the current development of traditional Chinese medicine components and problems, we discussed the standardization of traditional Chinese medicine components, with the aim of reducing and avoiding the situations to study non-traditional Chinese medicine components as traditional Chinese medicine components.
Drugs, Chinese Herbal
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chemistry
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Medicine, Chinese Traditional
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methods
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standards
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Reference Standards
2.Effective evaluation of brucellosis related risk behaviors of occupation groups and the effect of health education
Chinese Journal of Endemiology 2011;30(2):208-210
Objective To find out demography characteristic and risk behaviors of occupation groups and to evaluate the effect of health education. Methods A baseline survey was conducted among occupation groups in the western part of Liaoning province by stratified random cluster sampling. Health education started to intervene in occupation groups in Linghai city of Liaoning province. An investigation of brucellosis related behaviors was carried out before and after a health education among occupation groups. Other occupational groups were as the control group. The research on high-risk behaviors of occupation groups was in the following eight aspects: protection taken when contact with abortion livestock, timely slaughter and burying deeply of sick animals, not selling sick animals do not eat dead meat, nor drink raw milk, do not eat raw meat, and immunity of livestock. Results Before the intervention, a total of 916 objects, of which intervention group 499 and control group 417 were investigated. The high-risk behaviors of brucellosis were not significantly different between the two groups[70.9% (354/499), 64.3%(321/499 ), 53.8% (268/499), 92.2% (460/499), 82.2% (410/499 ), 87.5% (437/499), 93.6% (467/499), 56.2%(280/499) in intervention group, 68.8% (287/417), 59.2% (247/417 ), 54.7% (228/417), 89.2% (372/417 ), 85.6%(360/417) ,885%(369/417),94.0%(392/417),55.9%(233/417) in control group, all P > 0.05]. After the intervention,a total of 908 survey objects, of which intervention group 499 and control group 409, were investigated. The above eight aspects of high-risk behaviors in the intervention group were 85.4% (426/499),79.0% (394/499),69.9%(349/499),96.4%(481/499),943%(471/499),94.9%(474/499),94.0%(469/499), 99.4%(496/499), respectively; in the control 66.8% (273/409),57.3% (234/409),50.1% (205/409),85.3% (349/409),88.8% (363/409),89.5%(366/409) ,90.1% (369/409), and 57.2% (234/409), respectively. Between the two groups, the difference was statistically significant (x2 = 43.991,49.833,37.111,35.032,9.537,9.826,4.485,253.808, all P < 0.05 ). The above seven aspects of high-risk behaviors except do not eat raw dairy at the beginning of intervention were compared with those of after the intervention, the differences were statistically significant (x2 = 30.426,26.284,27.854,7.364,36.027,17.238,9270.286, all P < 0.05). Conclusions Health education intervention can significantly improve the behavior change rate of occupational groups at high risk of brucellosis, and the education intervention is worthwhile to communicate and promote.
3.Long stem bipolar arthroplasty for elderly patients with intertrochanteric fractures
Bin LIU ; Dan XIAO ; Shixing ZENG
Chinese Journal of Trauma 1993;0(05):-
Objective To evaluate the clinical result of long stem bipolar femur prosthetic replacement for elderly patients with intertrochanteric fractures.Methods A total 48 patients of intertrochanteric fractures,at age of 70 years or above,were treated with cemented long stem bipolar femur prosthetics.The surgery time,blood loss,Harris hip score and complication rate were observed.Results The average surgery time,the blood loss,Harris hip scores of the arthroplasty were 70 minutes,400 ml and 87 ml,respectively,without any complications.Conclusion Long stem bipolar femur prosthetic replacement can gain good hip function and decrease the complications of fracture in treating intertrochanteric fractures.
4.Investigation of the association between the macular volume and thickness by optical coherence tomography, with refraction state and axial length in children
Jingru XIAO ; Longqian LIU ; Dan MENG
Chinese Journal of Ocular Fundus Diseases 2008;24(2):114-117
Purpose To investigate the association between the macular volume and thickness,as assessed by optical coherence tomography(OCT),with refraction state and axial length(AL)in children.Methods A total of 100 normal children whose right eyes were randomly selected were divided into five groups due to their refraction,comprising hyperopia,emmetropia,low myopia,moderate myopia,high myopia.The AL of the eyes was measured by IOL master measuring machine.Then the macular volume and thickness were measured bv OCT.Results Children with high myopia have smaller macular volume and thinner parafoveal retinal thickness(especially out-ring macular).The minimum thickness and average thickness of the fovea were not significantly different among the five groups.The macular volume ,total average macular thickness and quadrant-specific macular thickness(except the nasal inner quadrants)were positively associated with refraction and negatively associated with AL,while there were no correlation between minimum foveal thickness,the average foveal thickness and refraction or AL.Conclusions In Chinese children,increasing axial length was associated with reduced maeular volume and thickness(except the foveal region and the nasal inner quadrant).
5.Study on preparation of salvianolic acid phospholipid compound.
Xiao-Yun CHEN ; Zhen-Hai ZHANG ; Dan LIU ; Dan-Hong YU ; E SUN ; Xiao-Bin JIA
China Journal of Chinese Materia Medica 2014;39(2):216-221
To prepare salvianolic acid phospholipid compound. With the compound of salvianolic acids and soybean phospholipid as the index, mono-factor experiment and orthogonal design experiment were conducted to screen its technical parameters. According to the results, the optimal preparation conditions of salvianolic acid phospholipid compound were that THF were taken as the reaction solvent, the concentration time was 3 h, the reactant concentration was 5 g x L(-1), the mass ratio of salvianolic acids and phospholipid was 1: 1.5, and the reaction temperature was 40 degrees C. The oil/water partition coefficient of the prepared salvianolic acid phospholipid compound significant increased in water and buffers with different pH values. The results of phase analysis such as DSC, XRD and FTIR indicated that salvianolic acids existed in phospholipid in an amorphous state.
Alkenes
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chemistry
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metabolism
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Chemical Phenomena
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Chemistry, Pharmaceutical
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methods
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Intestinal Absorption
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Phospholipids
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chemistry
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Polyphenols
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chemistry
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metabolism
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Soybeans
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chemistry
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Temperature
6.Biomechanical properties of a novel pourable cement pedicle screw and its application to osteoporotic lumbar degeneration
Yang LIU ; Dan LIU ; Yunxiang XIAO ; Haidan CHEN ; Hongwei ZHAO
Chinese Journal of Tissue Engineering Research 2016;20(31):4671-4676
BACKGROUND:Fragile bone in senile osteoporosis patients easily weakened pedicle screw fixation capacity. Therefore, bone cement leakage and screw removal cannot be solved during pedicle screw repair in osteoporotic patients with degenerative lumbar spine. OBJECTIVE:To investigate the biomechanical properties of novel pourable pedicle screws and bone cement application effect in osteoporotic patients with degenerative lumbar spine. METHODS:Six lumbar specimens (T11-L5) at the mean age of (72.9±4.2) years were selected, total y 42 vertebrae. The average bone density was 0.696 g/cm2. Any side of al vertebrae was inserted with pourable pedicle screws. 2 mL of bone cement was perfused under the X-ray fluoroscopy with cement push rod and fil ing cylinder. The same number of conventional screws was inserted into the opposite side of the samples. Three-point bending test was performed in two kinds of screws. The maximum vertebral axial pul out force test and the maximum spin torque test were conducted in vertebra to observe the destruction of the vertebral body and implanted effect. RESULTS AND CONCLUSION:(1) The ultimate strength and yield load of novel pourable cement pedicle screws were significantly more than conventional screws (P<0.05). Ultimate displacement and yield displacement were significantly less in novel pourable cement pedicle screws than in conventional screws (P<0.05). (2) The maximum vertebral axial pul out force and the maximum spin torque were significantly higher in novel pourable pedicle screws than in conventional screws (P<0.05). (3) In summary, novel pourable cement pedicle screw is simple to operate, can effectively control bone cement penetration, and improve screw stability in osteoporotic vertebrae. Moreover, after treatment, the removal of screws is convenient, cannot evidently destroy vertebral body or screw channel, and promote early recovery.
7.Temperature variation at the external root surface during Nd: YAG laser irradiation in the root canal in vitro.
Yuan-gao LI ; Xiao WANG ; Kexian XIE ; Dan LIU
West China Journal of Stomatology 2014;32(5):480-483
OBJECTIVETo assess the temperature variation of the root surface using Nd: YAG laser irradiation in the root canal with different power and to evaluate the safety of laser application on the periodontal region.
METHODSThirty extracted human teeth with single-roots were collected. The teeth were cross-sectioned in the cervical portion, standardizing the roots at a 12-mm length. The roots were used as specimen. The roots were radiographed in the buccal-lingual direction to measure the thickness of the proximal walls, by means of a digital radiographic system. The specimens were divided into three groups according to the laser potency (1.5, 3.0, and 4.5 W). Each group was subdivided into two subgroups according to laser frequency (15 and 30 Hz). With the Nd: YAG laser irradiation for 20 s, the temperature variation of the root surface was monitored by thermocouples located at different parts of the root external wall and recorded by digital thermometers.
RESULTSThe groups irradiated with 4.5 W presented the greatest temperature variation (above 10°C), followed by 3.0 and 1.5 W. The temperatures were statistically different (P < 0.01). The groups irradiated in the same potency, regardless of whether 15 Hz or 30 Hz was used, presented with no statistical difference (P > 0.05). The apical half of the root presented statistically higher temperature rises than the cervical half of the root (P < 0.01).
CONCLUSIONThe temperature variation of the root surface was associated with laser power, irradiation time, and the thickness of dentin. Application of Nd: YAG laser in the root at 1.5 W for 20 s can safely be used in endodontic treatment.
Dental Pulp Cavity ; Dentin ; Humans ; In Vitro Techniques ; Lasers ; Lasers, Solid-State ; Root Canal Therapy ; Temperature ; Tooth Root
9.Reflecting the Steps of Modernization of Chinese Materia Medica from the Papers in Chinese Traditional and Herbal Drugs in 2009
Yanze LIU ; Yang DAN ; Yong PENG ; Peigen XIAO
Chinese Herbal Medicines 2010;02(3):180-188
The papers in the journal of Chinese Traditional and Herbal Drugs in Vol.40,2009 are briefly reviewed in thecategories of chemical constituents,preparations and technologies,analysis and quality control,pharmacologicaland clinical studies,reviews,and finally healthy principles.Some comments,especially for hot topics have beenpersonally provided.
10.New Collection of Crude Drugs in Chinese Pharmacopoeia 2010 Ⅱ.Sankezhen (Berberis spp.)
Yang DAN ; Yanze LIU ; Yong PENG ; Zhongzhi QIAN ; Peigen XIAO
Chinese Herbal Medicines 2011;(4):268-284
Sankezhen (Berberidis Radix) is a traditional Chinese materia medica,cold in nature and bitter in taste,for treating syndromes of liver,stomach,and large intestinal meridians,in which berberine and berbamine are the major pharmacological components.Sankezhen has been readmitted in Chinese Pharmacopoeia 2010 following the 1977 version as the roots of Berberis spp.e.g.B.soulieana,B.wilsonae,B.poiretii,B.vernae,etc.Recent studies showed that Berberis spp.were potential phytomedicines with multiple spectrums therapeutic effects and various pharmaceutical parts.Here we reviewed Sankezhen in traditional use and phytochemistry,and its major active components berberine and berbamine with potential bioactivities recently discovered,such as antitumor,antidiabetic,antihyperlipidemic,anti-arrhythmic,and neuro-protective activities.It is necessary to mature the quality assessment of Sankezhen as a new admission of Chinese Pharmacopoeia 2010.Other parts of Berberis spp.should be investigated to better develop this herb in medicinal usage.