Hematopoietic Stem Cell Transplantation ; Humans ; Myelodysplastic Syndromes ; surgery

China ; Hematopoietic Stem Cell Transplantation ; Humans

Hematopoietic Stem Cell Transplantation ; Humans ; Leukemia ; therapy

China ; Hematopoietic Stem Cell Transplantation ; adverse effects ; methods ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; therapy

Graft vs Host Disease ; diagnosis ; therapy ; Hematopoietic Stem Cell Transplantation ; adverse effects ; Humans ; Postoperative Complications ; diagnosis ; therapy ; Transplantation Conditioning

Hematopoietic Stem Cell Transplantation ; Humans

China ; Humans ; Multiple Myeloma ; therapy

Objective:To prepare fluorouracil-loaded chitosan nanoparticle (5-Fu-CS-NP) for ophthalmologic usage and evaluate its releasing characteristics in vitro. Methods: 5-Fu-CS-NP was prepared with 5-Fu, polyacrylic acid and chitosan using dispersion method. The mean size, entrapment efficiency (EE%), drug loading (DL%) and the in vitro releasing characteristics of 5-Fu-CS-NP were investigated.Results and conclusion: The mean size of 5-Fu-CS-NP was (144.6?3.1) nm, the EE% was 84.5% and the DL% was 3.91%. 5-Fu-CS-NP had a satisfactory sustained-releasing effect and the releasing could last for 3-7 days, and the release behavior was not greatly changed within a pH value of 7.2-7.4.

Objective To observe the correlation of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) appearances and blood stasis syndrome in breast cancer.Methods The clinical data of 100 patients with breast cancer confirmed by operation and pathology were retrospectively reviewed.70 cases without blood stasis syndrome,30 cases with blood stasis syndrome.All the cases underwent MRI using PHILIPS Achieva 1.5T magnetic resonance scanner before surgery.Results In no blood stasis group,76.67％ inhomogeneous enhancement,edge enhancement 43.33％,spiculation proportion 50.00％,which were significantly lower than those in the blood stasis group (88.57％,75.71％,83.33％).The mass ratio of the shape between the two groups had no significant difference (P ＞ 0.05).No blood stasis group and stagnation of blood group TIC curve was mainly type Ⅳ,type Ⅲ curve ratio of no blood stasis group (3.33％) was significantly lower than blood stasis group(12.86％) (P ＜0.01).In blood stasis group,Emax/1 and tumor size were higher than without blood stasis syndrome group.the percentage of V per minute outflow of blood stasis group was lower than without blood stasis syndrome group.Conclusion The clinician should make a preliminary evaluation of the prognosis before operation,in order to timely and reasonably choose the method of integrated traditional Chinese and Western medicine.

The standard non-surgery approach for locally advanced non-small cell lung cancer (NSCLC) is concurrent chemoradiotherapy.Common chemotherapy regimens include EP,NP,DC and PC.New chemotherapy drugs combination and targeted therapy are still under study.The tolerances of elderly patients are declining for concurrent chemoradiotherapy,but it is not the absolute contraindication.The tolerance for hyperfraction and high dose radiotherapy is well,however,the effectiveness and long-term toxicity need to be further studied and evaluated.