Adolescent ; Age Factors ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Risk Factors ; Tachycardia, Supraventricular ; etiology ; pathology

AlM:To explore the clinical effects of using rigid gas permeable contact lens ( RGP ) for refractoriness amblyopia patients.
METHODS: Ninety - eight cases ( 98 eyes ) were voluntarily divided into RGP group and frame glasses group, and the two groups were received the regularity combined training to treat amblyopia for 6mo. We overviewed the corrected vision (on that day, 1, 3, 6mo) and the complication in RGP group .
RESULTS: The corrected vision in RGP group was obviously better than that in control group during the same time. The therapeutic efficacy in RGP group was better than that in frame glasses group, without serious complications at 6mo after treatment.
CONCLUSlON: RGP groups could get better corrected visual acuity. lt is safe and effective to improve corrected vision for refractoriness amblyopia patients.

Objective To study how polyclonal antibodies against ciliary neurotrophic factor (CNTF) reduce botulinum toxin-in- duced axonal sprouting and affect paralytic muscle.Design Experimental study.Participants 20 New Zealand rabbits.Methods In 10 rabbits randomly selected,left superior rectus were as control (Group 1),right superior rectus were injected with botulinum toxin A (BTXA) 2.5U (Group 3).At 14th day,bilateral superior recti were taken out under general anaesthesia.In the other 10 rabbits,left su- perior recti were injected equivalent physical saline (NS) as control (Group 2);right superior recti were injected with BTXA 2.5U,after 4 days,injected with 50?l polyclonal antibodies against CNTF at same site (Group 4).And at 14th day,bilateral superior recti were taken out for electron microscopy,dyed with acetylcholinesterase,argentums (Ag) to show nerve axonal sprout,and accounted and mea- sured with Leica microsystems.Main Outcome Measures The mean number of sprouts and the mean total length of sprouts,and the uhrastructure change of muscle by electron microscopy.Results In Group 1,the mean number of sprouts and the mean total length of sprouts were 5.75% and 10.53?m respectively;Group 2 were 6.11% and 11.16?m;Group 3 were 84.04% and 170.71?m;and Group 4 were 54.77% and 68.12?m.The differences were statistically significant (all P=0.000).Electron microscopy showed that after admin- istration BTXA alone (Group 3),muscle atrophied obviously,nerve myelin sheath increased,while the structure of nerve and muscle re- main invariable.The Group 4 showed that local myofilament disrupted and dissolved,degenerative myocytes necrotized and disintegrat- ed into fragments,which led to partial unreversible destroy.Conclusion Polyclonal anti-CNTF can reduce BTXA-induced axonal sprout- ing,lead to partial unreversible destroy of muscle,which may prolong the time of paralytic muscle resuming.It suggests that polyclonal anti-CNTF could prolong the duration of muscle paralyses induced by botulinum toxin.

Objective:To prepare the canine multivalence serum for emergent prevation and theatmentor canines infection disease.Methods:Selecting 20 healthy Kunming dog,which is more than one years old.The canines were immuned by regulary with Canine distemper virus(CDV),Canine parvovirus virus(CPV),Infectious canine hepatitis virus(ICHV),Canine coronavirus(CCV),Canine parainflu-enza virus(CPIV).The blood were draw in freedom germ from neck's artery at canines and then blood was centrifugate for isolating serum.To check antibody's tite, micro serum neutrolization(SN) and hemagglutination inhibition(HI) were used.Results:Canine multivalence serum is successfully preparation and good curative effects in clinic.Conclusion:Canine multivalence serum may be of great value in economics and society and contribute to curative disease.

Adolescent ; Adult ; Aged ; Alleles ; Child ; Female ; HLA-DR Serological Subtypes ; genetics ; Humans ; Male ; Middle Aged ; Myelodysplastic Syndromes ; diagnosis ; genetics ; pathology ; Prognosis ; Young Adult

Adolescent ; Adult ; Busulfan ; therapeutic use ; Female ; Hematopoietic Stem Cell Transplantation ; methods ; Humans ; Male ; Middle Aged ; Transplantation Conditioning ; methods ; Young Adult

Child ; Diarrhea ; diagnosis ; therapy ; Humans ; Practice Guidelines as Topic

Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell ; chemistry ; pathology ; Female ; Head and Neck Neoplasms ; chemistry ; pathology ; Humans ; Immunohistochemistry

Adenoma ; pathology ; Carcinoma ; pathology ; Carcinoma in Situ ; pathology ; Gastric Mucosa ; pathology ; Humans ; Neoplasm Invasiveness ; Precancerous Conditions ; pathology ; Stomach Neoplasms ; classification ; pathology

Objective To analyze the clinical effect of atorvastatin combined with conventional cardiovascu-lar drugs therapy in treatment of coronary heart disease.Methods 200 patients with coronary heart disease were col-lected.They were randomly divided into the observation group(n =100)and control group(n =100).The observation group was given atorvastatin combined with cardiovascular routine treatment for 1 year,the control group was given cardiovascular routine therapy for 1 year.The clinical effect and serum levels of TC,HDL -C,LDL -C were ana-lyzed.Results After treatment,the total effective rate of the observation group was 95%,which was significantly higher than 75% of the control group (χ2 =16.33,P =0.00 <0.05).According to the gender stratification,the effec-tive rates of the observation group were higher than the control group in men and women (men:96% vs 80%,χ2 =6.35,P =0.04 <0.05,women:94% vs 70%,χ2 =10.08,P =0.00 <0.05).Before treatment,there were no signifi-cant differences between the two group about the serum levels of TC,HDL -C,LDL -C[TC:(6.49 ±0.42)mmol/L vs (6.53 ±0.51)mmol/L,t =1.28,P =0.10 >0.05;HDL -C:(1.35 ±0.23)mmol/L vs (1.29 ±0.32)mmol/L, t =1.51,P =0.15 >0.05;LDL -C:(4.54 ±0.62)mmol/L vs (4.48 ±0.61)mmol/L,t =0.84,P =0.20 >0.05]. After treatment,the serum levels of TC,HDL -C,LDL -C of the observation group were significantly better than those of the control group[TC:(3.39 ±0.31)mmol/L vs (5.78 ±0.64)mmol/L,t =2.36,P =0.02 <0.05;HDL -C:(1.63 ±0.42)mmol/L vs (1.32 ±0.51)mmol/L,t =2.87,P =0.00 <0.05;LDL -C:(2.37 ±0.42)mmol/L vs (3.95 ±0.43)mmol/L,t =2.62,P =0.01 <0.05].Conclusion Atorvastatin can reduce blood fat,improve the prognosis of disease,it is superior to the traditional treatment.