1.Correlations between self-efficacy and self-care agency of the empty nest elderly with chronic ;disease in the community
Chinese Journal of Practical Nursing 2016;32(34):2693-2696
Objective To determine the status of self-efficacy and self-care agency of the empty nest elderly patients in the community,and analyze their correlation. Methods A total of 320 empty nest elderly with chronic disease in Fushun, Liaoning Province. The General Information Questionnaire, Exercise of Self-Care Agency scale (ESCA) and the Chronic Disease Self-efficacy Scale were used to investigate the empty nest elderly with chronic disease in the community and analyze the present situation level of the self-care agency and the self-efficacy and the correlation between them. Results General data showed no significant difference between solitary empty-nest elderly and connubial empty-nest elderly (P>0.05). Solitary empty-nest elderly got (93.36 ± 13.49) points and (5.22 ± 0.62) points in ESCA and the Chronic Disease Self-efficacy Scale,which were lower than (98.10±11.34) points and (5.32±0.30) points of connubial empty-nest elderly, the difference was statistically significant (t=-0.866,-0.467, P<0.05). There was significantly positive correlation between self-efficacy and self-care agency (r=0.318, P<0.01). Conclusions There is positive correlation between self-efficacy and self-care agency. It is suggested to implement community-based nursing interventions to enhance their self-efficacy and to promote their self-care agency,there by to improve their quality of life .
4.Non-coding RNAs and erectile dysfunction: An update.
National Journal of Andrology 2016;22(2):160-164
Erectile dysfunction (ED) is a disease associated with a variety of factors such as age, psychological factors, physical conditions, and lifestyle, and it severely affects the patients quality of life. In the past, some non-coding RNAs (ncRNAs) transcribed by genes but not translated into the protein were regarded as the "waste" in the process of gene expression. But in the recent years, ncRNAs have been found to play a crucial role in regulating gene expression and its products, which may affect penile erectile function. This review focuses on the recent progress in the studies of the relationship between ncRNAs and erectile dysfunction.
Erectile Dysfunction
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genetics
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Gene Expression
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Humans
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Male
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Quality of Life
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RNA, Untranslated
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physiology
5.Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis.
Acta Pharmaceutica Sinica 2011;46(5):568-72
Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods (including bio-potency and bio-activity fingerprint) were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the dao-di herbs and bioassay.
6.Study about Bacterial Translocation
Chinese Journal of Bases and Clinics in General Surgery 2003;0(02):-
Objective There are two main functions of gastrointestinal tract,digestion and absorption,and barrier function.The latter has an important defensive effect,which keeps the body away from the invading and damaging of bacteria and endotoxin.It maintains the systemic homeostasis.Intestinal dysfunction would happen when body suffers from diseases or harmful stimulations.The more serious intestinal disorders would harm the intestinal protective mechanism,or intestinal barrier function,and bacterial/endotoxin translocation,of intestinal failure(IF) would ensue.This article provides a critical review of the evidence indicating that an increase in bacterial translocation is associated with sepsis,and even the multiple organ failure syndrome in critically ill patients.The in-transit microorganisms play an essential role in the homeostasis of local and systemic immunity.Methods All studies published from 2000 to June 2005 about intestinal permeability,bacterial translocation,and systemic inflammatory response syndrome were located by search of PubMed.Results Clinical and experimental studies investigating the correlation between bacterial translocation and systemic inflammatory response syndrome,associated with the damage of the gut barrier function.To keep the mucosal barrier function intact is one of the main issues in the prevention of bacterial translocation.This could be achieved by the adequate delivery of oxygen and nutrient supplementation to the gut.Enteral nutrition,probiotic can be a good choice.Conclusion With a better understanding of the bacteria-host interactions in health and the alterations induced by critical illness,new therapies that improve the environment of both may lead to better recovery rates in intensive care unit patients.
9.Alterations of surfactant protein A and B in the early stage of acute lung injury in rats
Journal of Third Military Medical University 2001;23(2):154-156
Objective To study the alterations of surfactant protein A (SP-A) and B (SP-B) in rats in the early stage of acute lung injury induced by oleic acid. Methods An acute lung injury model was established by injecting oleic acid into the superior vena cava of rats and the levels of SP-A and SP-B in branchoalveolar lavage fluid (BALF) were determined with Western Blot and ELISA. Results The levels of SP-A and SP-B in BALF were significantly decreased in the injured group 1 h after acute lung injury (P<0.01) and remained low in the next 6 h. Conclusion The levels of SP-A and SP-B were decreased in the early stage of acute lung injury. The methods used for detecting SP-A and SP-B we adopted are specific and sensitive, and might be helpful for other experimental study.