Humans ; Myelodysplastic Syndromes ; diagnosis ; therapy

Natural killer cells,macrophages and neutrophils,as the body's natural immune cells,can respond quickly to the invasion of pathogens,is the basis for the development of specific immunity.Compared with the adaptive immune,anti-tumor effect of natural immune is weakeK Granulocytes can identify cancer cells,in the form of "rose petals"-like polymer,then release of toxins and dissolve cancer cells.

The fiercer competition in the health care market and the deepened reforming of medical and health system have led to the improvement of the hospital management.Whether the public hospital can timely adjust the management and business strategy is of critical importance to the sustainable development of hospitals.The man-agers should focus more on the brand marketing, defining the brand positioning and implementing the hospital brand marketing strategy which is centered on technology brand, service brand and culture brand, to gain competitive ad-vantages.With the strengthened core competitiveness, the hospital can achieve success in the competition.This paper took Fudan University Obstetrics and Gynecology Hospital ( OB/GYN hospital of Fudan University ) , also named Shanghai Red House OB/GYN hospital, as the research object to propose targeted brand marketing strategies based on the analysis of the current brand development of the Red House hospital.

AIM: To investigate the clinical effects on the deep lamellar keratoplasty for herpes simplex keratitis.
METHODS: Deep lamellar keratoplasty was performed on 105 cases with herpes simplex viral keratitis. All of these patients were followed-up for 12-36mo, the corneal graft transparency, visual acuity and viral keratitis recurrence were observed.
RESULTS:Among 24 patients after stripping the corneal stroma which was close to the Descemet's membrane, Central area of 81 cases were about 6mmí6mm of to Descemet's membrane. One hundred and one cases of planting beds were transparent. Visual acuity were improved in varying degrees, best corrected visual acuity was greater than 0. 5 in 67 cases, 0. 3-0. 5 in 35 cases, less than 0. 3 in 3 cases. There was no recurrence of viral keratitis and rejection cases during the observation period.
CONCLUSION: Deep lamellar keratoplasty is an effective technique in the treatment of viral keratitis. It is therefore should be an early surgical treatment for frequent episodes of viral keratitis cases.

Objective To review the clinical results of apisin to tuberculous exudatire pleurisy.Methods 60 patients with tuberculous exudatire plearisy were divided into two grups:conteol group and study group.In the control group,they were given 2HRIE/4HR.In the study group,the apisin was dripped into pleural cavity on the base of treat tuberculosis.Results The two group efficacious rate were 100%.The study group's efficacious rate was 90%.The controt group's efficcious.Rate was 63%.There was significant difference between the two groups(P

This article introduced the treatment experience of professor DING Shu-wen in these aspects: treating the risk factors of coronary heart disease,complicated with arrhythmia,developing to cardiac functional insufficiency,myocardiopathy stage,and still chest pain relentless after coronary artery intervention.In professor Ding's opinion,the treatment should base on combined syndrome and disease differentiation,especially syndrome differentiation.Modern medical results should be absorbed properly,too.The concrete contents are as follows: first,the medicine for coronary heart disease complicated with hyperlipemia can be classified into three types:1 Spleen-invigorating and kidney-nourishing Chinese herb medicine.2 Lipids lowering herbs proved by modern medicine.3 Chinese herbs of clearing heat-toxin aimed at pathogenesis of phlegm-stasis-heat impairing collateral.Second,stage treatment should be applied in coronary heart disease complicated with hypertensive disease.Third,invigorating qi and nourishing yin is the major method in treating coronary heart disease associated arrhythmia.Fourth,patients still with persistent chest pain after coronary artery intervention should be treated according to syndrome differentiation and rational use of medicine.

Professor DING Shu-wen is the internal well-known expert in the domain of angiocardiopathy. His idea on academic inheritance and innovation of TCM as follow:To combine the present-day clinic with the experience and thought of medication in ancient times which were refined from extensive archaic literature; To combine the TCM with Western medicine for bringing new ideas; To integrate current social circumstances with the feature of disease, and propose the toxic heat theory of angiocardiopathy disease; The increase of curative effect is the fundament of academic inheritance and innovation of TCM.

Retinal degeneration diseases is an irreversible neurodegenerative impairment.Nowadays,it has become one of the most common causes of blindness,but medical treatments showed little efficiency on these diseases.Recently,some researchers found that a series of transcription factors being capable of reprogramming DNA can reconstruct and induce somatic cells into pluripotent stem cells (iPSCs).The iPSCs not only have great potential of self-renew and differentiation,but also can avoid some critical issues such as ethical restrictions and immune suppression by using embryonic stem cells.Retinal stem cell therapy can also benefit from the ease of surgical access and observation of transplanted cells directly through the clear ocular media.These advantages make it possible for the iPSCs therapy to be a new approach to managing the retinal degenerative diseases in the future.The research history,feature and advantage,induce and directional differentiation of iPSCs were reviewed.

Guidelines for the Prevention of Stroke in Women released by the American Heart Association/American Stroke Association on February 6,2014,and this makes us have further reflection on the risk factors for ischemic stroke and prevention in women.Compared with men,some of risk factors are unique for women or more common in the female population.The in-depth understanding of the risk factors is essential for the prevention of ischemic stroke in women.

Objective To investigate the plasma PAF-AH level in type 1 diabetes patients and the association between the PAF-AH gene polymorphism and type 1 diabetes mellitus. Methods Plasma PAF-AH in115 type 1 diabetes patients and 106 controls were determined by PAF-AH assay kit, and PAF-AH gene G275A genotypes were detected by PCR-RLFP. Results The activity of plasma PAF-AH in the patients with type 1 diabetes was significantly lower than that in the controls. Compared with control group, the frequencies of the GA genotype on G275A polymorphism were significantly higher than that in T1DM group. Conclusion The activity of plasma PAF-AH in the patients with type 1 diabetes was significantly lower than that in normal controls. The G275A polymorphism of PAF-AH gene might be related to type 1 diabetes mellitus.