8.EFFECTS OF RESVERATROL ON BONE MINERAL DENSITY IN OVARIECTOMIZED FEMALE RATS
Acta Nutrimenta Sinica 2004;0(06):-
Objective: To investigate the effects of resveratrol(RES)on the bone mineral density (BMD) in ovariectomized female rats. Method: Forty-eight SD female rats were randomly divided into 6 groups and treated respectively as follows:group A, sham operated; group B, ovariectomized (OVX); group C, OVX supplemented with 0.03 mg/(kg bw ?d)diethylstilbestrol; and group D, E , F: OVX rats supplemented with RES at 5, 15 and 45 mg(/kg bw ?d). The duration of exposure was 90 d and the BMDs of rats were measured by dual-energy X-ray absorptiometry (QDR-4500A). Results: BMDs at all measured sites of group B were significantly lower than those of group A. And compared with group B, BMDs of the total body, lumbar vertebrae and femur of group D, E, F were increased significantly by RES. Conclusion: The bone loss of the ovariectomized female rats could be inhibited by RES. It seemed that the inhibitory effects of 45 mg/(kg bw ?d)RES on bone loss of ovariectomized female rats were better than the other 2 dosages or 0.03 mg/(kg bw ?d)diethylstilbestrol in this experiment.
9.Preparation and in vitro evaluation of fluorouracil nanoparticles for ophthalmologic usage
Academic Journal of Second Military Medical University 2000;0(10):-
Objective:To prepare fluorouracil-loaded chitosan nanoparticle (5-Fu-CS-NP) for ophthalmologic usage and evaluate its releasing characteristics in vitro. Methods: 5-Fu-CS-NP was prepared with 5-Fu, polyacrylic acid and chitosan using dispersion method. The mean size, entrapment efficiency (EE%), drug loading (DL%) and the in vitro releasing characteristics of 5-Fu-CS-NP were investigated.Results and conclusion: The mean size of 5-Fu-CS-NP was (144.6?3.1) nm, the EE% was 84.5% and the DL% was 3.91%. 5-Fu-CS-NP had a satisfactory sustained-releasing effect and the releasing could last for 3-7 days, and the release behavior was not greatly changed within a pH value of 7.2-7.4.
10.Outline of Ulcerative Colitis Treated by Acupuncture: A Review
Journal of Acupuncture and Tuina Science 2003;1(2):11-13
To analyze 73 theses that all accorded with statistical demand about ulcerative colonitis. The statistics found that the commonly used therapies were acupuncture, moxibustion, acupuncture-moxibustion, herbpartitioned moxibustion, acupoint-injection, point-radiation therapy, auricular-plaster therapy, catgut implantation at acupoint, point application etc. The commonlyused points were Zusanii ( ST 36), Tianshu ( ST 25),Pishu (BL 20), Weishu (BL 21), Zhongwan (CV 12),Dachangshu ( BL 25) etc. The total effective rate in clinic was 95.40%.