Objective To explore the clinical curative effect of moxa box moxibustion combined with acupoint application on postoperative urinary retention in patients with procedure for prolapse and hemorrhoid (PPH). Methods A total of 61 cases of postoperative urinary retention after 3 to 5 days of catheter removel in the Department of Anus and Intestine Surgery of Integrated Traditional Chinese and Western Medicine Hospital of Zhejiang Province from August 2015 to August 2016 were selected as the research objects. All the patients were assigned into observation group (n=31) and control group (n=30) by random number table method. All patients were treated with routine care before and after surgery. Basing on routine nursing, the observation group were given moxa box moxibustion combined with acupoint application therapy. The urination of the two groups after the treatment was observed and the effect was evaluated. Results The total effective rate of observation group was 93.55%, and the total effective rate of control group was 70.00%. The difference between the two groups was statistically significant (χ2=5.720, P=0.017). Conclusions Moxa box moxibustion combined with acupoint application can effectively prevent postoperative urinary retention of PPH. The operation is simple and easy to practice. The whole process is safe and noninvasive, takes less nursing time and easy to be accepted, which is worthy of clinical promotion.