1.On the Nurturance of All-around Students with the Theory of Respectful Educationin Military Academy
Liang ZHANG ; Xianzhu ZHAO ; Biyuan LI
Chinese Journal of Medical Education Research 2003;0(04):-
A new theory called respectful education has been brought up and studied in the preliminary education of ourcountry in recent years. It is the kind of education that calls for a respectful way of interaction among the supervisors,teachers and students and it mostly emphasizes the satisfaction of one's psychological need and the opportunity of anall-around development. As an important component of the quality education in our country, we military academy isundergoing a teaching reform, in which we have found the lack of training on our students' ability of innovative thinkingand nurturance of creativity and a good personality. Therefore, we borrow the ideas and experience presented in thetheory of respectful education in order to discuss the meaning of advocating the theory in the education in militaryacademy and the principles of applying the theory to the practice of education reform.[
2.Aptamers: characteristics and applications in pathogenic microorganism.
Hongru LIANG ; Songtao YANG ; Tao ZHANG ; Guiqiu HU ; Xianzhu XIA
Chinese Journal of Biotechnology 2011;27(5):698-703
Aptamers are a group of artificial oligonucleotides identified by exponential enrichment system evolution technology (Selective expansion of ligands by exponential enrichment, SELEX). Aptamers have been widely used in basic research, clinical diagnostics, and nano-technology. In this article we will introduce the technology of aptamer and summarize its applications in medical microbiology.
Aptamers, Nucleotide
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biosynthesis
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genetics
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Microbiological Techniques
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methods
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Microbiology
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SELEX Aptamer Technique
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methods
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trends
3.Expression and significance of serum leptin and lung tissue leptin receptor in rats with pulmonary arterial hypertension induced by monocrotaline
Tianci QIAN ; Xingxing PENG ; Xianzhu LIANG ; Fugui RUAN ; Jiangbin SUN ; Haiyong WANG
Chongqing Medicine 2018;47(1):11-13
Objective To study the significance of leptin and its receptor(OB-R) in the occurrence and development of pulmonary arterial hypertension(PAH) induced by monocrotaline(MCT).Methods Fifteen SD rats were divided into the control group(n=5) and two experimental groups(n=10).The experimental groups were intraperitoneally injected by MCT for constructing the PAH model and the control group was injected by the same dose of solvent groups.The venous blood was extracted at 2,4 weeks after MCT injection in the two experimental groups.The mean pulmonary artery pressure(mPAP) and right ventricular hypertrophy index(RVHI) were measured and then the lung tissue was removed.The pathological change of lung blood vessels was observed.The expression of serum leptin was detected by ELISA.The expression of OB-R in lung tissue was tested by Western blot.Results Compared with the control group,mPAP and RVHI in the experimental groups were significantly increased(P<0.05);the expression levels of serum leptin and lung tissue OB-R were increased significantly(P<0.05),moreover,which were positively correlated with mPAP(r=0.912,P<0.05;r=0.861,P<0.05).Conclusion Leptin and OB-R may play an important role in the occurrence and development of PAH induced by MCT.