1.The use of ultrasonically activated scalpel in modified radical mastectomy for breast cancer after neo-adjuvant chemotherapy
Journal of Endocrine Surgery 2012;06(2):106-108
ObjectiveTo discuss the clinical value of ultrasonically activated scalpel(UAS) in breast cancer patients who underwent 2-3 cycles of neo-adjuvant chemotherapy by comparing UAS and electric knives (EI) in modified radical mastectomy. MethodsFrom Jun.2009 to Aug.2011, 52 breast cancer patients taking 2-3 cycles of neo-adjuvant chemotherapy underwent modified radical mastectomy in our hospital. Among them, UAS group included 23 patients, and EI group included 29 patients.The 2 groups were compared in terms of the operation time, intraoperative blood loss, postoperative drainage tube duration, postoperative hospital stay, the number of lymph nodes retrieved, and the volume of subcutaneous hydrops.ResultsBetween the 2 groups, the difference of intraoperative blood loss and postoperative drainage tube duration had statistical significance(P <0.01 ).The difference of operation time, hospital stay, and subcutaneous hydrops had statistical significance ( P < 0.05 ).The difference of the number of lymph nodes retrieved had no statistical significance ( P > 0.05 ).ConclusionThere are good curative effects for breast cancer patients undergoing modified radical mastectomy by UAS and axillary lymph node dissection after neo-adjuvant chemotherapy, which is consistent with the conception of fast track surgery.
2.Diagnosis,treatment and medical evaluation of anatomical abnormalities in nasal cavity in aircrew
Xianrong XU ; Yang ZHANG ; Xiaoli MA
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective To sum up the experiences of diagnosis,treatment and medical evaluation of the anatomical abnormalities in nasal cavity(AANC,including deviation of nasal septum and turbinate hypertrophy) in aircrew.Methods Case data of 91 pilots with CANC were analyzed.The classification and typing of AANC and secondary barotraumas associated with typing of AANC were studied.Results There were 50 cases of class I AANC(with symptoms or signs on ground),41 cases of class II(no symptoms or signs on ground but with symptoms of secondary barotraumas in flight,including IIa 10 cases:with symptoms of secondary barosinusitis,IIb 26 cases:with symptoms of secondary barotrauma of ear,IIc 5 cases:with symptoms of secondary barosinusitis and barotrauma of ear after flying).For the typing of AANC,there were 41 cases of nasal septum deviation,29 cases of inferior turbinate hypertrophy,8 cases of middle turbinate hypertrophy,and 13 cases of nasal septum deviation and turbinate hypertrophy.85 cases were still in a qualified position to continue their flying job,1 pilot was transferred from fighter to transport pilot,2 pilots were temporarily grounded,and 3 were permanently grounded.Conclusions AANC is very common in aircrew.AANC in aircrew is classified and typed according to the effect of gas pressure adjustment functions of ear and nasal sinus.The classification and typing are of important implication in clinical aviation medicine.Medical workers must unify the qualification criteria in selection for air candidates,and also in diagnosis,treatment,medical evaluation of disease in aircrew.This is an important measure to improve the health quality and ensure combat effectiveness for the air force.
3.Studies on the Identification and Analysis of Borneol
Qiaug WANG ; Xianrong YANG ; Jinquan CHEN
Chinese Traditional and Herbal Drugs 1994;0(05):-
Three species of borneol from different origins, namely Borneol Camphor (extracted fromDryobalanops aromatica Gaerth. f. ), Balsamiferous Blumea Borneol (extracted from Blumeabalsamifera DC. ) and synthetic borneol, were studied by macroscopic and microscopic iden .tification and GC method. Their differences were revealed. The amount of borne0l and isob-orneol in the samples were determined.
4.Effect of Zhi Qing Capsule on the Atherosclerosis of Rabbits
Fei YANG ; Xianrong LI ; Yong KANG
Traditional Chinese Drug Research & Clinical Pharmacology 1993;0(02):-
Objective To observe the effect of Zhi Qing Capsule on the plaque formation of hyperlipemia rabbits and to discuss its mechanism.Methods Forty-eight New-Zealand rabbits were randomly divided into normal control group,hyperlipemia group,Xuezhikang control group and three Zhi Qing capsule groups.Before and after 2-week treatment,the serum levels of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C) and high density lipoprotein cholesterol(HDL-C) in the serum were determined.After 4-week treatment,TC and TG contents in the liver,and nitric oxide(NO),thromboxan B2(TXB2) and endothelin-1(ET-1) levels in the serum were measured.At the end of the sixth week,all rabbits were killed to observe aorta pathological changes.Results Zhi Qing Capsule can obviously counteract the increase of serum TC,LDL-C and liver TC in the hyperlipemia rabbits,restrain the formation of aorta atherosclerotic plaques,increase the level of NO and decrease the levels of TXB2 and ET-1.Conclusion Zhi Qing Capsule has an evident effect on resisting the lipid metabolism disturbance and atherosclerosis.
5.Metastasis rule and influence factors analysis of cervical central group lymph node in patients with papillary thyroid microcarcinoma
Mingxing LIAO ; Ditian ZHANG ; Xianrong YANG
Chinese Journal of Postgraduates of Medicine 2014;37(26):51-53
Objective To study the metastasis rule and influence factors of cervical central group (Ⅵ region) lymph node in patients with papillary thyroid microcarcinoma.Methods The clinical data of 195 patients with papillary thyroid microcarcinoma were analyzed retrospectively.All patients received bilateral thyroidectomy and bilateral cervical central group lymph node dissection.Results All patients died without surgery and hospitalization,the incidence of postoperative complications was 2.1% (4/195).The total incidence of cervical central group lymph node metastasis was 35.4% (69/195).Factors relating to cervical central group lymph node metastasis rate were:age (OR =0.924),gender (OR =0.213),the number of foci (OR =2.208) and the sum of the tumor diameters (OR =2.106).Conclusions Patients with papillary thyroid microcarcinoma may suffer from lymph node metastasis of the cervical central group,and lymph node metastasis rate increases significantly in young or male patients,and when the lesions are multifocal or the sum of the tumor diameter > 0.5 cm.
6.The influence on smoking and drinking status of officers and soldiers after health management
Zhenzhen WANG ; Xianrong LUO ; Xuan YANG ; Jun YANG ; Shaen LI
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(3):261-263
Objective To investigate the influence of smoking,drinking cognition and behavior among the officers and soldiers in South China War Zone after health management,and to explore the establishrent of appropriate health management model for the army.Methods Harmfulness cognition,rate,quantity,types of drinking and smoking were investigated and analyzed before and after health management among 1 102 officers and soldiers in South China War Zone by providing a set of health education,psychological counseling service,disease and lifestyle intervention of health management as a whole.Results The harmfulness cognition rate of smoking and drinking raised from 95.6% and 94.1% to 98.7% and 97.8%,the smoking and drinking rate dropped from 64.7% and 72.6% to 37.2% and 61.4% after health management.The x2 values were 18,18.9,153,20.8,and had significant difference (P<0.001).The rate of occasional smoking,a small amount of smoking,often smoking dropped from 28.3%,25.8%,45.9% to 18.5%,12.2%,31.5% as well as the rate of occasional drinking,a small amount of drinking,often drinking has dropped from 56.6%,32.3%,11.1% to 49.8%,23.4%,4.1%.The x2 values were 26.8,62.1,31,9.61,8.06,19.4,and had significant difference (all P<0.01).Conclusion The health management improves the harmfulness cognition of smoking and drinking,and decreases the rate and quantity of smoking and driking.It has a positive effect on improving the heahh literacy and developing health way of life in officers and soldiers.
7.The Application of Vestibular Functional Test in the Diagnosis and Evaluation of Flight Illusion in Pilots
Zhanguo JIN ; Xianrong XU ; Yuhua LIU ; Yang ZHANG
Journal of Audiology and Speech Pathology 2004;0(06):-
0.05). ②Among 30 pilots with abnormal vestibular functions,19 were permanently grounded and 11 were permitted to return their flying station. 36 pilots returned to fly in 45 cases with normal vestibular functions. The permanently grounded rate had significant differences between the two groups with normal and abnormal vestibular functions. (P
8.Respiratory Support of Pressure Regulated Volume Control Ventilation after Liver Transplantation
Xianrong LUO ; Guobing ZENG ; Shuren LIU ; Jun YANG
Chinese Journal of Bases and Clinics in General Surgery 2008;0(08):-
Objective To study the application of pressure regulated volume control ventilation in respiratory support after liver transplantation.Methods Twenty patients underwent liver transplantation were randomly averagely divided into two groups: pressure regulated vlume control ventilation(PRVCV) group and volume control(VC) group.The parameters of respiratory mechanics,hemodynamics and blood gas analysis of patients in two groups were compared,such as oxygen delivery(DO2),oxygen consumption(VO2),oxygen incepation ratio(O2ER),arteriovenous oxygen content difference(C(a-v)O2),cardiac output(CO),mean arterial pressure(mABP),mean pulmonary arterial pressure(mPAP),alveolar-arterial PO2 difference(P(A-a)O2),gas exchange index(PaO2/FiO2),ratio of shunted blood to total perfusion(Qs/Qt),peak inspiratory pressure(PIP) and mean airway pressure(mAP).Results The P(A-a)O2 and Qs/Qt were significantly decreased in PRVCV group than those in VC group(P(A-a)O2:(101.42?28.07) mm Hg vs.(136.76?39.13) mm Hg;Qs/Qt:(1.78?0.86)% vs.(3.28?0.99)%),P
9.Preparation of rivastigmine liposome and its pharmacokinetics in rats after intranasal administration.
Zhenzhen YANG ; Zhanzhang WANG ; Kai WU ; Xianrong QI
Acta Pharmaceutica Sinica 2011;46(7):859-63
To prepare rivastigmine liposome, rivastigmine was loaded into liposome via ammonium sulfate gradient method. Its pharmacokinetic profile in rats was evaluated after intranasal administration. The size, zeta potential, entrapped efficiency and release of rivastigmine from the liposome in vitro were determined. Plasma concentration of rivastigmine was determined by high performance liquid chromatography-tandem mass spectrometry (HPLC/MS) using antipyrine as internal standard. The pharmacokinetic parameters were calculated by DAS 2.0. The entrapped efficiency of rivastigmine liposome was (33.41 +/- 6.58) %, with the mean diameter of 154-236 nm and zeta potential of (-10.47 +/- 2.41) mV. The release behavior of rivastigmine was fitting the first order equation in vitro. The pharmacokinetic studies indicated that the C(max), T(max) and AUC(0-infinity), of rivastigmine liposome were (1.50 +/- 0.15) mg x L(-1), 15 min and (89.06 +/- 8.30) mg x L(-') x min, respectively. Rivastimine liposome was absorbed rapidly, and could reach a certain concentration in rat plasma after intranasal delivery.
10.Construct management and monitoring platform of TCM information system based on open source software
Li KANG ; Haiyan LI ; Deli YANG ; Xianrong WEN ; Qiang LI
International Journal of Traditional Chinese Medicine 2010;32(6):520-522
Config and modify open source software such as Nagios、 MRTG and Awstats, make it more suitable and stable for our network environment. Construct server monitor、 service monitor、 network monitor and website statistics system by using open source software. Besides, we construct network resource management system via ASP and database technology.Finish the network and service monitoring and management system based on B/S architecture. This system can keep close watch on the status of servers and services running on servers, and ensure all of the servers and services normal running, and provide the basic information service for policy-making body and other research institute.