Twenty-three patients with pain from osteoporotic vertebral fractures,aged 65-90 yr,weighing 51-78 kg,received an image intensifier-assisted nerve-root block with a 6-8 ml mixture of 0.5 ％ lidocaine,mecobalamine 0.5 mg and betamethasone sodium phosphate injection 5.26 mg in a prone or lateral position.The VAS scores before operation,at 0,1 week,1 and 3 months after operation were 8.6 ± 0.9,1.5 ± 0.7,2.8 ± 0.9,1.6 ± 0.5 and 2.5 ± 0.7,respectively.VAS scores were significantly lower at each time pint after operation than before operation (P ＜ 0.05).According to modified MacNab standard,the effectiveness of treatment was rated as excellent/good in 87％ of the patients.No complication such as bleeding,hematoma,infection,pneumothorax,hemopneumothorax,headache was found during or after operation.Selective nerve-root block is effective in the treatment of pain resulting from osteoporotic vertebral fractures in patients.

Objective To investigate the real experiences of nurses participating in the treatment of patients with new respiratory infectious diseases. Method The semi-structural interview method was used to carry out in-depth interviews with 8 nurses who were involved in the whole process of treatments and cares of patients with SARS and H1N1 influenza to understand their real experiences. Result The nurses, who participated in the treatment and care to patients with new respiratory infectious diseases, experienced such emotions of nervousness, excitement, anxiety, fear, exhaustion, obtained support from their families, hospitals, society and meanwhile recognized their lack of professional knowledge and clinical skills. Conclusion The nurses participating in the treatment of patients with new respiratory infectious diseases should be given strengthened professional training , psychological and social support.

This article reviews the concept, classification, screening and evaluation tools of cognitive frailty, and research in chronic diseases of the elderly, with the aim of improving the awareness and understanding of cognitive frailty among medical and nursing staff. It is recommended to further strengthen the research on cognitive frailty in elderly patients with chronic diseases, optimize screening tools, and promote the construction of targeted intervention programs, so as to provide a basis for the research progress of cognitive frailty in elderly chronic diseases in China.

Objective To explore the influence of acupuncture point massage combined with limb function exercise on ankle brachial index (ABI) and pulse wave velocity (PWV) in patients with coronary heart disease (CHD). Methods According to scores by grace score scale, 180 CHD patients were divided into three groups: low risk group (n=58), moderate risk group (n=68) and high risk group (n=54). Within the three groups, the patients were divided into the experiment group and the control group by using the random digital table. The control group was treated with routine nursing intervention , while the experiment groups accepted acupuncture point massage and limb function exercise training on the basis of control groups. We collected the values of ABI and PWV at four points-in-time: before intervention, 7 days after intervention, 30 days after intervention and 90 days after intervention. Results Repeated measurement data analysis of the experiment group and control group suggested that:in the moderate and high risk groups, there was statistically significant difference (P<0.05) in the data at the four time points. There was no statistically significant difference (P > 0.05) in time and group interaction effect. The difference between the experiment group and control group was statistically significant (P<0.05). Repeated measurement data analysis showed that there was no statistically significant difference (P>0.05) in ABI&PWV interaction effect at the four time points between the experiment group and control group. In the low-risk group,the differences in time points compared with the main effect were insignificant (all P>0.05). In comparison of main effect at all the four time points, there was significant different in the moderate and high risk group (P<0.05), And it suggested that time and group interaction, namely effect of time factor (1 d, 7 d, 30 d, 90 d), was not decided by the division of groups. In comparison of main effect, the difference was statistically significant (all P < 0.01) in the moderate and high-risk group, which indicated the main effect (intervention) playing main role. However, there was no statistically significant difference (P>0.05) of ABI&PWV before and 90-days after intervention. Conclusion Acupuncture point massage combined with limb function exercise can effectively improve the peripheral artery blood supply in CHD patients, lower ABI and promote PWV.

Objective:To investigate the psychological state and influencing factors of clinical front-line nurses in response to public health emergencies.Methods:We used stratified cluster random sampling method to survey 1187 front-line clinical nurses from February to March, 2020, using the Psychological Questionnaire for Emergent Events of Public Health.Results:The questionnaire survey showed that the scores for dimensions of depression, neurasthenia, fear, obsessive-anxiety and hypochondria were (0.52±0.02), (0.37±0.01), (0.87±0.02), (0.24±0.01) and (0.25±0.01), respectively. There were statistically significant differences in scores of hypochondriac dimension for clinical nurses at different hospital levels ( F=4.30, P<0.05), and there were statistically significant differences in scores of depression, neurasthenia, obsessive-anxiety and hypochondriac dimension for nurses in different nursing units ( F values were 4.34-11.11, all P<0.05). Multiple linear regression analysis showed that the nursing unit factors had influence on depression, neurasthenia, obsessive-anxiety and hypochondria. Conclusions:Clinical front-line nurses experienced negative psychology such as depression, neurasthenia and fear in public health emergencies. As a manager, it is necessary to strengthen preventive psychological counseling, do a good job in the theory, operation and protection knowledge training for public health emergencies, humanistic care, establish a good organizational atmosphere to maintain the physical and mental health of clinical nurses, and ensure the quality and safety of nursing.

Objective To explore the effects of peer support education on the compliance and quality of life in patients with liver cirrhosis complicated with upper gastrointestinal bleeding.Methods A total of 60 patients with liver cirrhosis complicated with upper gastrointestinal bleeding during January 2015 and December 2016 were selected in this study using convenient sampling. Patients who treated from January to December 2015 were included in the control group (n=30) and those treated from January to December 2016 were included in the observation group (n=30). Patients in the control group adopted routine nursing. Based on the routine nursing care, the observation group received additional peer support education. The medication adherence questionnaire and the MOS Item Short Form Health Survey (SF-36) were used to compare the compliance and quality of life before and after the intervention within two groups.Results After six months of intervention, the intervention group had significantly better compliance compared with the control group [(1.23±0.76) vs (2.23±1.45);t=3.144,P<0.05]. The scores of SF-36 (except health dimension) were significantly higher in the observation group compared with the control group (P<0.05).Conclusions Peer support education may be helpful in improving the medication compliance and quality of life in patients with liver cirrhosis complicated with upper gastrointestinal bleeding.

Objective To investigate the mechanism of white matter damage (WMD) and the neuroprotective effect of Xenon on neonates with WMD.Methods Three-day-old SD rat pups (n =96) were randomly divided into the blank control group (n =24),the WMD control group (n =24),the Xenon intervention group A (n =24) and the Xenon intervention group B (n =24) by random number method according to their birth time.WMD rat models were successfully established by giving intraperitoneal injection of lipopolysaccharide(LPS) 0.05 mg/kg combined with carotid artery ligation and hypoxia for 1 hour in the WMD control group and the Xenon intervention groups.In the control group,only 9 g/L saline (0.05 mg/kg) was injected intraperitoneally,while carotid artery ligation and hypoxia were not administered.Rats in Xenon intervention group A and group B were given inhalation of 500 mL/L Xenon for 3 hours at 0 and 2 hours respectively after establishment of the models.Six rats in each group were randomly selected and decapitated at 0,24,48 and 72 hours after the intervention.The brain white matter on the right was analyzed by using HE staining and myelin basic protein(MBP) immunofluorescence staining,and real-time quantitative polymerase chain reaction was used to detect the expressions level of CLIC4 mRNA.Results (1) Brain tissue pathology:compared with the blank control group,the brain white matter on the right of the WMD control group and the Xenon intervention group A and group B had loose and disordered structure,nuclear pyknosis and cytoplasm loosening.However,the lesions in both Xenon intervention group A and group B were significantly less than those in the WMD control group,and there was no significant difference between the Xenon intervention group A and group B.(2) MBP measurement:the number of MBP-positive cells in the brain white matter on the right of WMD control group was significantly lower than that in the blank control group,while compared with WMD control group,they were significantly higher in Xenon intervention group A and group B.(3) CLIC4 mRNA expression level:compared with blank control group,the expressions levels of CLIC4 mRNA at most time point were higher both in the WMD control group and the Xenon intervention group A and group B (all P ＜ 0.05),except the time point 24 h in the Xenon intervention group A.The expressions of CLIC4 mRNA in group A and group B were significantly decreased compared with those in the WMD control group (all P ＜ 0.05).However,there were no significant differences between Xenon intervention group A and group B (P ＞ 0.05).Conclusions The expressions of CLIC4 mRNA in brain tissues on neonatal rats with WMD significantly increased,indicating that the mitochondrial pathway could be one of the pathological processes of WMD.Early Xenon intervention may reduce neonatal WMD by reducing the expression of CLIC4 mRNA,which plays a neuroprotective role.

Objective To explore the empowerment education application effect on the healthy education for patients with hepatitis B cirrhosis. Methods A total of 100 cases of hepatitis B cirrhosis decompensation were selected from January to May 2017 in a ClassⅢ Grade A infectious disease specialist hospital in Nantong with convenience sampling method. All the research subjects were divided into observation group and control group by random number table method, with 50 cases in each group. Routine health guidance of clinical pathway was conducted for the control group, and empowerment education based on routine education was carried out for the observation group. Before and after the intervention, self-management behaviors, the incidence rate of cirrhosis complications and nursing job satisfaction in the two groups were compared respectively. Results There were 1 death case in the observation group and 2 cases discharged after 3 days in the control group during the intervention. Finally, there were 49 cases in the observation group and 48 cases in the control group. The evaluation scores of self-management behaviors which includes diet management, daily life management, medication administration, disease monitoring management were higher than those in the control group. The differences were statistically significant(t=-4.047, -3.635, -3.437, -3.831; P＜0.05). Satisfaction with nursing service which includes service attitude, communication ability, humanistic care and theoretical guidance in the observation group was significantly higher than that in the control group. The differences were statistically significant (χ2=7.789, 6.804, 6.557, 6.239; P＜ 0.05). The incidence rate of cirrhosis complications which includes hepatic encephalopathy and electrolyte disorder was lower than that in the control group, and the differences were statistically significant (χ2=4.549, 4.401; P＜ 0.05). Conclusions Empowerment education can improve self-management behavior of patients with hepatitis B cirrhosis and satisfaction, and reduce the incidence rate of complications.

Objective To investigate the core competence, self-efficacy and correlation of geriatric clinical front-line nurses in Nantong medical institutions, and to analyze the influencing factors of the two, so as to provide reference for the formulation of training programs for geriatric clinical front-line nurses. Methods Using convenience sampling method, the geriatric clinical front-line nurses in Nantong medical institutions were investigated by Geriatric Nursing Competency Inventory (GNCI) and General Self-Efficacy Scale (GSES) from October to December 2017. Single factor analysis, Pearson correlation and multiple linear regression were used to analyze the correlation between core competence and self-efficacy of geriatric clinical nurses and the influencing factors. Results The score of GNCI was (2.51±0.64), and the score of GSES was (2.60±0.65). Pearson correlation analysis showed that core competence of geriatric nursing was positively correlated with self-efficacy (r=0.472, P＜0.01). There were significant differences in the scores of GNCI of geriatric clinical front-line nurses with different ages, working years, educational background, professional title, marriage, personnel nature, number of night shifts on duty, whether they were teaching, professional interests, whether accept advanced study in superior hospitals and family support (P＜ 0.05). There were significant differences in the scores of GSES among clinical front-line geriatric nurses with different ages, marriages, number of night shifts on duty, whether they were teaching, professional interests and family support (P＜0.05). Multivariate linear regression analysis showed that professional interest was the influencing factor of core competence of geriatric nursing (P＜0.05). Conclusions The core competence of clinical front-line nurses in Geriatrics Department is low, and their self-efficacy is moderate. There is a positive correlation between them. As a nursing administrator in Geriatrics Department, it is significant to strengthen the training of clinical front-line nurses, constantly improve the training curriculum and career planning, and improve the core competence and self-efficacy of geriatric nursing.

Objective? To explore the competitive attitude of clinical nurses of Infectious Disease Department and its influencing factors so as to provide a basis for improving nursing management strategies of infectious disease further. Methods? From April 2017 to June 2017, we selected 454 clinical nurses of Infectious Disease Department from 8 Class Ⅲ hospitals in Nantong City as subjects by convenience sampling. The Competitive Attitude Scale (CAS) was used to investigate the score of competitive attitude of clinical nurses of infectious disease department and multiple linear regression was used to analyze its influencing factors. Results? Among 454 clinical nurses of Infectious Disease Department in Nantong City, the scores of benign competition attitude and excessive competition were (45.13±8.17) and (29.57±5.51) respectively. There were statistical differences in the scores of excessive competition among clinical nurses of infectious disease department with different work lives and professional titles (F=3.147,3.556; P＜ 0.05). Multiple linear regression showed that the influencing factors of excessive competition included work lives and professional titles (P＜0.01). Conclusions? Clinical nurses of Infectious Disease Department have the low score of competitive attitude. The work lives and professional titles are the influencing factors of excessive competition. Nursing managers of infectious disease department should establish a reasonable competitive mechanism to allow full paly to benign competition, avoid excessive competition and improve whole competitiveness.