1.Clinical Observation on Treatment of Pediatric Diarrhea with Traditional Chinese and Western Medicine
Xiangyu HU ; Xinzheng HAO ; Xing LIU
International Journal of Traditional Chinese Medicine 2008;30(4):285-286
Objective To study the clinical effects of tearing pediatric diarrhea with traditional Chinese and western medicine.Methods Altogether 520 patients with pediatric diarrhoea were recruited into three groups:the group treated with combined traditional Chinese and western medicine,the group treated with Chinese medicine and the group treated with western medicine.Observe clinical effects of each group.Results In 175 cases of the group treated with combined traditional Chinese and western medicine,66 cases show significant effects,64 cases are effective,45 eases are ineffective,and the effective rate is 74.30%;In 171 cases of the group of treated with traditional Chinese medicine,32 eases show significant effects,42 eases are effective,97 cases are ineffective,and the effective rate is 43.30%;In 174 eases of the group of treated with western medicine,35 eases show significant effects,43 eases are effective,96 eases are ineffective,and the effective rate is 44.80%.The effective rate of the group treated with combined Chinese medicine and western medicine was significantly better than the other two groups (P<0.01).Conclusion Combined Chinese and western medicine is more effective in treating the patients with pediatric diarrhea,and it is worthy of spread.
2.RANDOMIZED DOUBLE-BLIND CLINICAL TRIAL OF THE ANTIHYPERTENSIVE EFFICACY OF BISOPROLOL,ENALAPRIL AND NIFEDIPINE RETARD ON PATIENTS IN THE TROOPS IN DIFFERENT GEOGRAPHICAL REGIONS
Guoshu LIU ; Mingfeng LI ; Xiangyu SHI
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
0 05). For enalapril treatment, the total efficacy rate in patients in Tibet and coastal areas was 96 0% and 77 6%( P 0 05).
3.Effects of an electromagnetic field on the proliferation and osteogenic differentiation of bone mesenchymal stem cells
Xiangyu TANG ; Tao FU ; Yang LIU ; Chaoxu LIU
Chinese Journal of Physical Medicine and Rehabilitation 2017;39(8):566-571
Objective To explore the effect of an electromagnetic field (EMF) on the viability,proliferation and osteogenic differentiation of rats' bone mesenchymal stem cells (rBMSC).Methods Sinusoidal 1mT EMFs of 10 Hz,30 Hz,50 Hz and 70 Hz were administered to rBMSC for 2 hours per day during 2 weeks of cultivation.The cell viability was analyzed using live/dead assays.The cells' DNA was quantified to evaluate cell proliferation.Von Kossa staining was performed to study the mineralization of the extracellular matrix.The enzyme linked immunosorbent assay (ELISA) and immunohistological staining were employed to observe the synthesis of osteocalcin (OC) and bone morphogenetic protein-2 (BMP-2).Results Cell viability decreased under exposure to the 50 Hz and 70 Hz fields.The proliferation of rBMSC was elevated significantly in the 10 Hz EMF-treated group.The expression OC and BMP-2 was elevated after two weeks of 50 Hz EMF stimulation.Moreover,the mineralization of the extracellular matrix was found to be enhanced after 50 Hz EMF exposure.Conclusion Exposure to a 1 mT EMF has different effects on the viability,proliferation and osteogenic differentiation of rBMSC depending on the frequency.The data provide practical guidance for applying electromagnetic fields in bone regenerative medicine.
4.The correlation between the mindfulness level and the behavior characteristics of the nursing college students
Huayun LIU ; Yongyi CHEN ; Lianqing ZHOU ; Xiangyu LIU
Chinese Journal of Practical Nursing 2013;29(32):10-12
Objective To investigate the relationship between the level of mindfulness and the A-type behavior characteristics of the nursing college students.Methods 172 nursing college students were investigated by the scale of TABP and FFMQ.The results were analyzed.Results In the 172 nursing college students,there were 112 nursing college students belonging to type B behavior pattern,accounted for 65.1%,and 60 nursing college students belonging to type A behavior pattern,accounted for 34.9%.The correlation between the score of TABP and the observation items and describing items were positive statistically significant,and was negatively correlated with awareness items and non-judge items statistically.Conclusions The students with different behavior characteristics were different in their mindfulness level.In order to improve nursing college students' mindfulness level and their mental health,the educators should take intervention based on their behavior characteristics timely.
5.Effects of electrical stimulation of vagus nerve on gut injury following intestinal ischemia-reperfusion in rats
Chuiliang LIU ; Yujuan LI ; Xiangyu LI ; Kexuan LIU ; Wenqi HUANG
Chinese Journal of Pathophysiology 2000;0(07):-
AIM: To investigate the effects of electrical stimulation of vagus nerve on gut injury following intestinal ischemia-reperfusion in rats. METHODS: 30 adult male Wistar rats subjected to bilateral cervical vagotomy were randomly divided into three groups (n=10 per group): (1) Intestinal ischemia-reperfusion group (group I/R): laparotomy and I/R induced by clamping arteria mesenterica superior for 1 h followed by reperfusion for 2 h. (2) Vagus nerve stimulation group (group VNS): laparotomy, I/R and electric stimulation with pulse train of constant amplitude 5V, pulse width 2 ms and frequency 1 Hz at the left caudal vagus ends for 20 minutes before and after occlusion. (3) Sham control group (group SC): sham operation and sham stimulation. Carotid artery was cannulated for mean arterial pressure (MAP) monitoring. A strip of small intestine was taken from distal end of ileum for light microscopic (LM) and transient electron microscopic (TEM) examination at the time of 2 h after reperfusion. Improved Chiu’s scale was used to quantitatively assay the damage degree. The levels of malondialdehyde (MDA) and TNF-? in plasma were detected. RESULTS: MAP in every group kept steady during ischemia, but decreased gradually with the prolongation in the time of reperfusion. MAP decreased more dramaticly in group I/R than that in group VNS (P
6.Comparison of RapidArc plans and fixed field intensity modulated radiotherapy planning in cervical cancer radiotherapy
Xiangyu LIU ; Xianfeng LIU ; Yanan HE ; Wenjuan YIN ; Yongzhong WU
Chinese Journal of Radiological Medicine and Protection 2011;31(3):326-328
Objective To explore the advantages and disadvantages between the RapidArc plans and fixed-field IMRT plan (IMRT).Methods Ten cases of cervical cancer,aged 55 (36-70),who were to receive post-operative radiotherapy were selected randomly.Single arc (Arc 1),two arcs (Arc 2),and three arc (Arc 3) RapidArc plans and fixed-field IMRT plan were designed respectively in the Eclipse 8.6 planning system.The designing,treatment time,target area,and dose distribution of organs at risk by these 4 planning techniques were compared.Results The values of average planned treatment time by the Arc 1,Arc 2,and Arc 3 ten cases was 98,155,185,and 46 min,respectively.The values of average treatment time in the Varian IX accelerator were 2.15,3.32,4.48,and 6.95 min,respectively.The average mean doses were (48.99±1.08),(49.40±0.51) ,(49.51±0.62) ,and (48.65±0.92) Gy,respectively.The values of homogeneity index (HI) of target were 1.11±0.07,1.07±0.02,1.06±0.02,and 1.12±0.05,respectively.The values of eonformal index (CI) of target were 0.73±0.13,0.87±0.06,0.87±0.06,and 0.79±0.06,respectively.The doses at rectum,bladder,and small intestine calculated by IMRT plan were the lowest,and the doses at the femoral neck calculated by these 4 plans were similar.Conclusions The RapidArc plan is superior in dose distribution at target,HI,CI,and treatment time to IMRT,but IMRT plan is superior to RapidArc in planned dose calculation time and protection of organs at risk.However,in general,the RapidArc plan is better in clinical application than IMRT plan.
7.Effect of DuSuQing granula on expression of inflammatory factor in small intestine tissue of rabbit model of endotoxin-induced lung injury
Suyun LI ; Jiansheng LI ; Xiangyu WANG ; Baojun LIU
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Objective:To explore effect of DuSuQing granula on expression of inflammatory factor in small intestine of rabbit model of endotoxin-induced lung injury .Method:Rabbit model of lung injury was established by intravenous injection of lipopolysaccharide.36 white male flap-eareds were randomly divided into six groups:Normal control group,model group,DSQ high dosage group,DSQ middle dosage group,DSQ low dosage group and ShuangHuangLian( SHL) group.The expression of macrophage,s TNF-?,ICAM-1,VCAM-1 in small intestine tissue were analyzed by immunohistochemistry.Results:The expression of macrophage,TNF-?,IL-1,ICAM-1,VCAM-1 in model group was markedly higher than that in normal group(P
8.Clinical research on modified Yanghe decoction revised on pulmonary interstitial fibrosis
Xiangyu LIU ; Aiping JIA ; Yanlei GE ; Lirui ZHANG
International Journal of Traditional Chinese Medicine 2013;35(4):310-312
Objective To investigate the curative effect of modified Yanghe decoction on pulmonary interstitial fibrosis.Methods In this study,62 patients suffering fiom pulmonary interstitial fibrosis were randomly divided into 2 groups with the use of the Random Number Table method.31 cases in the treatment group were treated with modified Yanghe decoction,while 31 cases in the control group were treated with prednisone,40 mg/d (produced by Zhejiang Xianju Pharmaceutical Factory).The dosages of prednisone were gradually reduced a month later.The changes and improvement in symptoms,pulmonary function,chest CT,etc were observed and analyzed after three month.Results The study showed that the total?effective?rates of the treatment group and control group were 83.9% (26/31) and 58.1% (18/31) respectively,and the difference had statistical significance (P=0.031,P<0.05).The integrals of gasping,breathlessness,cough and Velcros Rale of the treatment group before the treatment were (3.1 ± 2.61),(4.1 ± 1.53),(1.38 ± 1.02),(1.56 ±2.34)respectively while those of the control group were (2.83±2.34),(3.90±1.67),(1.28±1.24),(1.61±2.14) respectively.The after-treatment integrals of the treatment group were (1.1 ± 1.06),(1.52± 1.40),(0.36±0.71),(0.65±0.67)respectively while those of the control group were(1.2± 1.33),(2.15±1.31),(0.41±0.70),(0.78 ± 0.30)respectively.Compwered with their symptoms before the treatment,there was obviousimprovement in the symptoms of both groups after the treatment,(P<0.05),but the difference in these aspects between the two groups had no statistical significance (P>0.05).Before the treatment,the total lung capacity,vital capacity,diffusion function,arterial oxygen pressure of the treatment group were (69.80±21.7) %,(73.16±16.38) %,(51.46± 16.42) %,(69.70± 10.74) mm Hg (1 mm Hg=0.133 kPa) respectively while those of the control group were(77.52 ± 15.96)%,(74.57 ± 20.73)%,(55.68 ± 17.27)%,(64.86 ± 11.40)mm Hg respectively.After the treatment,the total lung capacity,vital capacity,mass function,arterial oxygen pressure of the treatment group were (82.31±21.65)%,(83.66±17.32)%,(62.34±17.96)%,(83.51±9.37)mm Hg respectively while those of the control group were (85.06± 16.10) %,(85.72± 20.40) %,(68.32± 20.16) %,(79.61 ±9.41)mm Hg respectively.Compwered with their symptoms before the treatment,there was obvious improvement in the symptoms of both groups after the treatment (P<0.05),but the difference in these aspects between the two groups had no statistical significance (P>0.05).Conclusion Modified Yanghe decoction can be effectively applied in the prevention and treatment of pulmonary interstitial fibrosis.
9.Level and Significance of Inflammatory Cytokines in Patients with Acute Deep Venous Thrombosis of Lower Extremity
Xiangyu ZHOU ; Yanzheng HE ; Chunshui HE ; Yong LIU
Chinese Journal of Bases and Clinics in General Surgery 2003;0(06):-
To study the significance of the levels of plasma inflammatory cytokines (IL-6,IL-8,IL-10 and TNF-?) in patients with acute deep venous thrombosis (DVT) of lower extremity. Methods Forty untreated DVT cases were selected as the subjects in the DVT group, while thirty healthy subjects, whose ages and genders showed no significant difference with the DVT patients, were collected as the control group. The plasma levels of IL-6, IL-8 and TNF-? were detected by radioimmunoassay (RIA), and the plasma level of IL-10 was measured by enzyme-linked immunosorbent assay (ELISA). Correlation analysis was used to investigate the relationships between the levels of different inflammatory cytokines within DVT group. Results The levels of plasma cytokines in the DVT group were all significantly higher than those in control group (P
10.DEVELOPMENTAL ALTERNATIONS IN PROPRIOCEPTIVE AFFERENT PROJECTIONS IN THE MOUSE SPINAL CORD
Jing HUANG ; Feng FENG ; Xiangyu LIU ; Yunqing LI ; Shengxi WU
Acta Anatomica Sinica 2006;37(1):12-16
Objective To observe the developmental changes of projection and termination of proprioceptive afferent fibers in the mouse spinal cord. Methods Parvalbumin (PV) immunohistochemistry was used to label the proprioceptive afferents. Single and dual immunofluorescence histochemistry were used to examine the growth pattern of proprioceptive afferents and their relationships with motoneurons in the spinal ventral horn (VH). The stained sections were observed under a confocal laserscanning microscope. Results PV-like immunoreactive (LI) proprioceptive fibers first appeared in the dorsal column on embryonic (E) day 14, then entered the gray matter on El5 and reached the intermediate gray matter and VH more obviously on E16. The number and intensity of PV-LI proprioceptive afferent fibers and punctata increased in the VH with age and reached a maximum during earlier postnatal (P) period (P0-P7). After P14, the number and intensity of proprioceptive afferents gradually decreased. The proprioceptive terminals seemed to form close relationship with motoneurons from E17. Conclusion The present study indicates that the somatotopic organization of proprioceptive afferents in the spinal cord is established during the late embryonic and early postnatal stages. These results provide evidence for understanding the development of the reflex movements.