Objective To learn current needs of and satisfaction with health management among liver or kidney transplant recipients.Methods Our data,including needs of and satisfaction with physical or mental management and social supports,were from China Transplant Recipients Health Research Project.Chi-square test was used for data analysis.Results There was a gap between needs of and satisfaction with knowledge management of surgical operation and medication (x2 values were 22.2 and 34.2,respectively ; both P ＜0.05).No significant difference was found between needs of and satisfaction with knowledge management of appetite,energy status and physical comfort (x2 values were 25.5,30.7 and 26.3,respectively; all P ＜0.05).Difference between needs of and satisfaction with respection or understanding and support from family numbers,trust by colleagues and friends,stress release,personal performance and success,social support,friend making,leisure and entertainment activities,and improved quality of life was statistically significant (x2 values were 46.5,43.4,39.2,19.2,31.9,23.7,117.7,258.4,59.6 and 33.3,respectively ; all P ＜0.05).Conclusion Management of disease,medication,and physiological-psychological-social supports may affect health outcomes of transplant recipients,and current health management system could not meet the needs of this population.

30?) and 33 subjects of low angle (MP/FH

0 05). For enalapril treatment, the total efficacy rate in patients in Tibet and coastal areas was 96 0% and 77 6%( P 0 05).

Benign biliary strictures(BBS) have different etiologies, and the most common causes are strictures secondary to iatrogenic and ischemic injury after hepatobiliary and transplantation surgery. Fibroblast proliferating activity, extracellular matrix overdeposition and scar proliferation are closely related to BBS. The mechanism of development of BBS involves a variety of cells, cytokines and extracellular matrix. In recent years, biological treatment is emerging as an effective option for BBS, but the clinical application is not yet mature and the curative effect needs to be evaluated further in the future.

Objective To develop and identify the monoclonal antibodies (McAbs) against Region II~+ motif in circumsporozoite protein of Plasmodium falciparum. Methods BALB/c mice were immunized with 12 peptides within Region Ⅱ~+ in circumsporozoite protein of P. falciparum. Spleen cells isolated from the immunized mice were fused with myeloma cell. After three times screening with ELISA, 3 positive hybridoma cell lines were obtained. Results ELISA test indicated that the McAbs reacted with recombinant circumsporozoite protein fragment containing tandemly repeat region and conserved Region II~+. IFA test showed that the McAbs recognized not only the sporozoites of P. falciparum, but also the sporozoifes of P. yoelii. Conclusion McAbs obtained can probe the Region II~+ motif in circumsporozoite protein of P. falciparum, which might also recognize that of other Plasmodium species.

Objective To investigate the characteristics of the occurrence of bully/victim incidents among children and to explore children's implicit attitudes towards the phenomenon of being bullied.These children were grouped into 4 types,which were the bully children,the victim children,the bully/victim children and the non-involved children,respectively.Methods The stratified cluster sampling method was used to extract 1 100 pupils from 3 primary schools in Henan area.The 1 100 children were investigated with bully/victim questionnaire (pupil version).Among them,78 children who were involved in bullying(including 30 bully children,18 victim children and 30 bully/victim children) and 29 non-involved children were selected and investigated with implicit association test(IAT).Results 1.Among all the 1 029 effective participants,74 were the bully children,121 were the victim children and 101 were the bully/victim children.The total number of those were in bullying amounted to 296,which meant that about 28.8％ (296/1 029 cases) children were involved in the issue of bullying.2.In general,the subjects showed significant differences between compatible task reaction time (1 324.083 ± 458.373) ms and incompatible task reaction time (1 463.963 ± 501.254) ms in IAT (t =3.063,P ＜ 0.01).3.Among the 4 types of children,bully/victim children showed significant differences between compatible task reaction time(1 237.838 ±449.731) ms and incompatible task reaction time (1 428.754 ± 539.634) ms in IAT (t =2.301,P ＜ 0.05).Non-involved children also showed significant differences between compatible task reaction time (1 512.389 ± 557.354) ms and incompatible task reaction time (1 777.404 ± 441.373) ms in IAT(t =3.129,P ＜ 0.01).4.Bully children didn't show obvious differences between compatible task reaction time (1 304.007 ± 400.530) ms and incompatible task reaction time (1 287.236-± 405.017)ms in IAT (t =0.308,P ＞ 0.05).Victim children didn't show obvious differences between compatible task reaction time (1 178.900 ± 280.539) ms and incompatible task reaction time (1 292.635 ± 467.531) ms in IAT (t =0.821,P ＞ 0.05).Conclusions Children's implicit attitudes towards being bullied are negative,considering it as not good.Non-involved children and bully/victim children show more negative implicit attitudes towards being bullied.

OBJECTIVE: To analyze the recurrencerelative factors of early glottic carcinoma after carbon dioxide laser treatment. METHOD: A retrospective analysis of 134 early glottic carcinoma patients' clinical data was taken to analyze the relationships between recurrence and gender, age, pathologic degree, T stage, involvement of anterior commissure and involvement of thyroarytenoid muscle. RESULT: Recurrent ratio of well-differentiated, middle-differentiated and poorly-differentiated squamous cell carcinoma were 11.83%, 18.42% and 33.33% (P > 0.05) respectively. Recurrent ratio of T1a, T1b, T2 were 13.24%, 18.92%, 23.08% (P > 0.05) respectively. The recurrent rate was 33.33% of tumors offended the anterior commissure, versus 5.43% with no involvement of anterior commissure (P < 0.01). The recurrent rate was 59.09% of tumors offended the thyroarytenoid muscle, versus 5.36% with no involvement of thyroarytenoid muscle (P < 0.01). Unvaried and multivariate analysis indicated that the involvement of anterior commissure and the involvement of thyroarytenoid muscle were the factors of recurrence. CONCLUSION Recurrence of early glottic carcinoma after carbon dioxide laser treatment is effected by the involvement of anterior commissure and the involvement of thyroarytenoid muscle. Resection can be performed conservatively according to evaluation of macroscopic tumour extension.
Carcinoma, Squamous Cell ; surgery ; Glottis ; Humans ; Laryngeal Neoplasms ; surgery ; Laryngectomy ; Laser Therapy ; Lasers, Gas ; Microsurgery ; Neoplasm Recurrence, Local ; Retrospective Studies

Objective To investigate the practical value of Shikani optical stylet used for orotracheal intubation in critically conscious patients and to evaluate the successful rate. Method A total of 48 conscious patients with severe respiratory failure were selected from January 2008 to June 2009. Of them, there were 31 males and 17 females,aging 21-86 years old with an average of 57 years old. All enrolled patients needed endotracheal intubation for mechanical ventilation support, and they were assigned to Shikani group (group S, n = 25) and Macintosh group (group M, n = 23) according to the odd and even number of date of admission to this study. The time consumed for intubation, the number of failure in intubation, the adverse effects or complications such as hemodynam-ic changes, injury to the pharyngo-oral cavity, choking and breath-hold were observed and recorded. The rank test and chi-square test were used for statistical analysis. Results The ratio of the successful intubation at first attempt was much higher in group S (96.0%) than that in group M (60.9%) (P <0.01). Compared with group M, the time consumed for intubation was significantly shortened, the cardiovascular reactions were much mild, and the incidence of injury to pharyngo-oral cavity, choking and breath-hold were less in the group S ( P < 0.01 all). Conclusions For the acute and critical patients, especially the conscious ones, orotracheal intubation with the Shikani optical stylet is rapid, successful, safe and less injurious, resulting in mild cardiovascular reactions.

Objective To investigate the impact of thyrotropic hormone (TSH) on recurrence rate of common bile duct stone (CBDS).Methods The clinical data of 268 cases of primary or recurrent CBDS undergoing surgery was analyzed.According to whether screening preoperative TSH level routinely,we assigned the patients into two groups,unchecked group with 171 cases and screened group with 97 cases.The postoperative recurrence rates in 36 months between two groups were compared.Results The recurrence rates of unchecked group and screened group were 3.5％,12.9％,16.9％ and 0.0％,5.2％,8.2％ respectively in 12-,24-,36-months,there was statistically significant difference between two groups (x2 =4.029,P ＜ 0.05).In unchecked group,patients ≥ 60 years had a significant higher recurrence rate than ＜ 60 years patients (x2 =6.485,P ＜ 0.05).In screened group,there was no statistically significant difference between ≥60 and ＜ 60 patients (x2 =0.142,P ＞ 0.05).In those 34 patients with a high TSH level in the screened group,normalizing the level from (6.23 ± 1.44) μIU/ml to (2.91 ±0.74) μIU/ml by oral intake of thyroid hormone postoperatively,led to the recurrence rates of 0％,5.9％,8.8％ in 12-,24-,36-months,which was not significantly different from those with normal TSH (x2 =0.022,P ＞ 0.05).And that,there was not statistically different between the young and elder patients in those 34 cases for the 12-,24-,36-month recurrence rates (x2 =0.086,P ＞ 0.05).Conclusions Some CBDS patients may be with high level of TSH.Normalizing TSH level may be conducive to a reduced postoperative recurrence rate of CBDS.

Objective:To investigate the anticaries effects of hesperidin in rats.Methods:The MIC of hesperidin against Streptococ-cus sobrinus(S.sobrinus)was explored with disc diffusion method.The rats with artificial caries were administered with 1/2 MIC hes-peridin,0.12%Chlorhexidine and distilled water respectively.The results of S.sobrinus level,Keyes scoring and DIAGNOdent exam-ination were used to evaluate the effects of hesperidin on S.sobrinus and caries development.Results:The MIC of hesperidin agaist S. sobrinus was 8 mg/ml.The S.sobrinus level was not statistically different between hesperidin group and negative control group(P>0. 05).Keyes scores of grade E of smooth and pit and fissure caries in hesperidin group were lower than in negative control(P<0.05), those of grade Ds and Dm of pit and fissure caries in hesperidin group were lower than in negative control(P<0.05 ),while higher than in chlorhexidine group(P<0.05).Hesperidin showed significant anti-caries effect(P<0.05)examined by DIAGNOdent.Con-clusion:Hesperidin at 1/2 MIC has anti-caries effect in rats without influence of the oral microecological balance.