1.Needs of and satisfaction with health management among patients undergoing liver or kidney transplantation
Chinese Journal of Health Management 2013;(3):167-170
Objective To learn current needs of and satisfaction with health management among liver or kidney transplant recipients.Methods Our data,including needs of and satisfaction with physical or mental management and social supports,were from China Transplant Recipients Health Research Project.Chi-square test was used for data analysis.Results There was a gap between needs of and satisfaction with knowledge management of surgical operation and medication (x2 values were 22.2 and 34.2,respectively ; both P <0.05).No significant difference was found between needs of and satisfaction with knowledge management of appetite,energy status and physical comfort (x2 values were 25.5,30.7 and 26.3,respectively; all P <0.05).Difference between needs of and satisfaction with respection or understanding and support from family numbers,trust by colleagues and friends,stress release,personal performance and success,social support,friend making,leisure and entertainment activities,and improved quality of life was statistically significant (x2 values were 46.5,43.4,39.2,19.2,31.9,23.7,117.7,258.4,59.6 and 33.3,respectively ; all P <0.05).Conclusion Management of disease,medication,and physiological-psychological-social supports may affect health outcomes of transplant recipients,and current health management system could not meet the needs of this population.
2.Study on implicit attitudes of children towards the phenomenon of being bullied
Meng WU ; Lujun SHEN ; Xiangyu LI
Chinese Journal of Applied Clinical Pediatrics 2014;29(7):527-529
Objective To investigate the characteristics of the occurrence of bully/victim incidents among children and to explore children's implicit attitudes towards the phenomenon of being bullied.These children were grouped into 4 types,which were the bully children,the victim children,the bully/victim children and the non-involved children,respectively.Methods The stratified cluster sampling method was used to extract 1 100 pupils from 3 primary schools in Henan area.The 1 100 children were investigated with bully/victim questionnaire (pupil version).Among them,78 children who were involved in bullying(including 30 bully children,18 victim children and 30 bully/victim children) and 29 non-involved children were selected and investigated with implicit association test(IAT).Results 1.Among all the 1 029 effective participants,74 were the bully children,121 were the victim children and 101 were the bully/victim children.The total number of those were in bullying amounted to 296,which meant that about 28.8% (296/1 029 cases) children were involved in the issue of bullying.2.In general,the subjects showed significant differences between compatible task reaction time (1 324.083 ± 458.373) ms and incompatible task reaction time (1 463.963 ± 501.254) ms in IAT (t =3.063,P < 0.01).3.Among the 4 types of children,bully/victim children showed significant differences between compatible task reaction time(1 237.838 ±449.731) ms and incompatible task reaction time (1 428.754 ± 539.634) ms in IAT (t =2.301,P < 0.05).Non-involved children also showed significant differences between compatible task reaction time (1 512.389 ± 557.354) ms and incompatible task reaction time (1 777.404 ± 441.373) ms in IAT(t =3.129,P < 0.01).4.Bully children didn't show obvious differences between compatible task reaction time (1 304.007 ± 400.530) ms and incompatible task reaction time (1 287.236-± 405.017)ms in IAT (t =0.308,P > 0.05).Victim children didn't show obvious differences between compatible task reaction time (1 178.900 ± 280.539) ms and incompatible task reaction time (1 292.635 ± 467.531) ms in IAT (t =0.821,P > 0.05).Conclusions Children's implicit attitudes towards being bullied are negative,considering it as not good.Non-involved children and bully/victim children show more negative implicit attitudes towards being bullied.
3.RANDOMIZED DOUBLE-BLIND CLINICAL TRIAL OF THE ANTIHYPERTENSIVE EFFICACY OF BISOPROLOL,ENALAPRIL AND NIFEDIPINE RETARD ON PATIENTS IN THE TROOPS IN DIFFERENT GEOGRAPHICAL REGIONS
Guoshu LIU ; Mingfeng LI ; Xiangyu SHI
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
0 05). For enalapril treatment, the total efficacy rate in patients in Tibet and coastal areas was 96 0% and 77 6%( P 0 05).
4.Molecular mechanism of benign biliary stricture and biological therapy
Xiangyu WANG ; Lijun LI ; Zhiqiang ZHENG
Chinese Journal of Hepatobiliary Surgery 2011;17(6):518-520
Benign biliary strictures(BBS) have different etiologies, and the most common causes are strictures secondary to iatrogenic and ischemic injury after hepatobiliary and transplantation surgery. Fibroblast proliferating activity, extracellular matrix overdeposition and scar proliferation are closely related to BBS. The mechanism of development of BBS involves a variety of cells, cytokines and extracellular matrix. In recent years, biological treatment is emerging as an effective option for BBS, but the clinical application is not yet mature and the curative effect needs to be evaluated further in the future.
5.Preparation and Identification of Monoclonal Antibodies against the Region II~+ Motif in Circumsporozoite Protein of Plasmodium falciparum
Ruijuan ZHANG ; Huaimin ZHU ; Xiangyu LI
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(02):-
Objective To develop and identify the monoclonal antibodies (McAbs) against Region II~+ motif in circumsporozoite protein of Plasmodium falciparum. Methods BALB/c mice were immunized with 12 peptides within Region Ⅱ~+ in circumsporozoite protein of P. falciparum. Spleen cells isolated from the immunized mice were fused with myeloma cell. After three times screening with ELISA, 3 positive hybridoma cell lines were obtained. Results ELISA test indicated that the McAbs reacted with recombinant circumsporozoite protein fragment containing tandemly repeat region and conserved Region II~+. IFA test showed that the McAbs recognized not only the sporozoites of P. falciparum, but also the sporozoifes of P. yoelii. Conclusion McAbs obtained can probe the Region II~+ motif in circumsporozoite protein of P. falciparum, which might also recognize that of other Plasmodium species.
6.Multiple regression analysis of the mechanism of hyperdivergency and hypodivergency development
Tong LI ; Xiangyu YE ; Hong ZHOU
Journal of Practical Stomatology 2000;0(05):-
30?) and 33 subjects of low angle (MP/FH
7.Evaluate the related factors of recurrence after carbon dioxide laser in treatment of early glottic carcinoma.
Yanhong HU ; Donghai WANG ; Xiangyu LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(22):1774-1776
OBJECTIVE:
To analyze the recurrencerelative factors of early glottic carcinoma after carbon dioxide laser treatment.
METHOD:
A retrospective analysis of 134 early glottic carcinoma patients' clinical data was taken to analyze the relationships between recurrence and gender, age, pathologic degree, T stage, involvement of anterior commissure and involvement of thyroarytenoid muscle.
RESULT:
Recurrent ratio of well-differentiated, middle-differentiated and poorly-differentiated squamous cell carcinoma were 11.83%, 18.42% and 33.33% (P > 0.05) respectively. Recurrent ratio of T1a, T1b, T2 were 13.24%, 18.92%, 23.08% (P > 0.05) respectively. The recurrent rate was 33.33% of tumors offended the anterior commissure, versus 5.43% with no involvement of anterior commissure (P < 0.01). The recurrent rate was 59.09% of tumors offended the thyroarytenoid muscle, versus 5.36% with no involvement of thyroarytenoid muscle (P < 0.01). Unvaried and multivariate analysis indicated that the involvement of anterior commissure and the involvement of thyroarytenoid muscle were the factors of recurrence.
CONCLUSION
Recurrence of early glottic carcinoma after carbon dioxide laser treatment is effected by the involvement of anterior commissure and the involvement of thyroarytenoid muscle. Resection can be performed conservatively according to evaluation of macroscopic tumour extension.
Carcinoma, Squamous Cell
;
surgery
;
Glottis
;
Humans
;
Laryngeal Neoplasms
;
surgery
;
Laryngectomy
;
Laser Therapy
;
Lasers, Gas
;
Microsurgery
;
Neoplasm Recurrence, Local
;
Retrospective Studies
8.Normalizing TSH level prevents postoperative recurrence of common bile duct stone
Yixing REN ; Jingdong LI ; Xiangyu PENG ; Guogang ZHAO ; Qiang LI
Chinese Journal of General Surgery 2014;29(7):510-513
Objective To investigate the impact of thyrotropic hormone (TSH) on recurrence rate of common bile duct stone (CBDS).Methods The clinical data of 268 cases of primary or recurrent CBDS undergoing surgery was analyzed.According to whether screening preoperative TSH level routinely,we assigned the patients into two groups,unchecked group with 171 cases and screened group with 97 cases.The postoperative recurrence rates in 36 months between two groups were compared.Results The recurrence rates of unchecked group and screened group were 3.5%,12.9%,16.9% and 0.0%,5.2%,8.2% respectively in 12-,24-,36-months,there was statistically significant difference between two groups (x2 =4.029,P < 0.05).In unchecked group,patients ≥ 60 years had a significant higher recurrence rate than < 60 years patients (x2 =6.485,P < 0.05).In screened group,there was no statistically significant difference between ≥60 and < 60 patients (x2 =0.142,P > 0.05).In those 34 patients with a high TSH level in the screened group,normalizing the level from (6.23 ± 1.44) μIU/ml to (2.91 ±0.74) μIU/ml by oral intake of thyroid hormone postoperatively,led to the recurrence rates of 0%,5.9%,8.8% in 12-,24-,36-months,which was not significantly different from those with normal TSH (x2 =0.022,P > 0.05).And that,there was not statistically different between the young and elder patients in those 34 cases for the 12-,24-,36-month recurrence rates (x2 =0.086,P > 0.05).Conclusions Some CBDS patients may be with high level of TSH.Normalizing TSH level may be conducive to a reduced postoperative recurrence rate of CBDS.
9.Long-term care needs and its influencing factors among elderly people living in rural areas of Beijing
Xingming LI ; Yifan LI ; Yuan MA ; Mengxuan ZOU ; Xiangyu KUANG
Chinese Journal of Health Management 2013;7(6):369-374
Objective To understand current status and influencing factors of long-term care for elderly people who lived in rural areas of Beijing.Methods A total of 1022 elderly people (age>60 years old) were enrolled in this cross-sectional study during December,2012 and January,2013.Demographic information,health status and needs of and intent to long-term care were learned through a questionaire survey.Chi-square test and muhiple non-conditional logistic regression analysis were used to identify the factors that were related to the respondents' selection.Results Nearly 6.6% (61/1016) participants showed needs for long-term care.82.3% (841/1013) respondents preferred household-based long-term care,while 7.53% (77/1013) preferred community-based long-term care.In single factor analysis,education level,occupation,household income,living conditions,number of children living together,medical insurance,pension insurance,chronic diseases and self-report hearing ability,taste and touch were related with longterm care needs (x2values were 33.03,136.17,99.32,88.83,58.07,147.71,108.11,9.85,33.78,30.45 and 22.22,respectively; all P<0.05).Multivariate analysis showed that occupation,income per capita,spouses living conditions,new corporative medical systems and self-report visual status were correlated with household-based long-term care (odds ratio (OR) were 2.48 (95% confidence interval (CI) 1.21-5.10),0.82(0.71-0.95),1.64 (1.08-2.49),4.78 (2.93-7.82) and 0.72 (0.59-0.89),respectively).Conclusion Householdbased long-term care and health management system may be needed and chosen by the elderly living in rural areas of Beijing.
10.Endovascular interventional treatment of carotid artery injury
Sheng LI ; Baomin LI ; Jun WANG ; Xiangyu CAO ; Chengjian SUN
Chinese Journal of Trauma 2008;24(5):383-386
Objective To evaluate the efficacy and safety of the endovascular interventional minimally invasive techniques(IMIT)for treatment of carotid artery iniury. Methods A total of 111 cases of carotid artery injury diagnosed by digital subtraction angiography(DSA)were treated with IMIT.Except for 1 case of extracranial segment injury of internal carotid artery treated with transcatheter stentgraft placement to obturate the rupture of carotid artery,the other 110 cases of intracranial segment injury of internal carotid artery(ICA)were treated with embolization with balloons in 73,embolization with coils in 12,injection of NBCA and PVA in 6,stent-graft placement in 11 and embolization with multiple materials in 8. Results Angiography demonstrated rupture of extracranial segment of internal carotid artery and arteriovenous fistula(AVF)at the neck in 1 case,traumatic carotid cavernous fistula(TCCF)in 83.traumatic pseudoaneurysm at intracranial segment of carotid artery in 14 and both TCCF and pseudoaneurysm in 13.The interventional treatment succeeded in all cases and interual carotid arteries were well protected in 62 cases.Completion angiography documented complete obliteration of the fistulas,with complete disappearance of the clinical symptoms in 110 cases and improvement in 1.Minor complications occurred in 2 cases,without death occurred.During the follow-up for 1-14 months,16 cases reexamined with DSA,which showed that the symptoms of 3 cases reoccurred,2 of whom were cured by re-embolization and 1 was under clinical observation. Conclusions IMIT including transcatheter selective embolization and stent-graft implantation is minimally invasive,safe and effective for treatment of carotid artery injury.