1.The Application Status and Prospect of Metal Drugs in Antibacterial Field
Guoheng LI ; Jintao WANG ; Weiping SHI ; Xiangwen LIAO
Journal of Nanjing University of Traditional Chinese Medicine 2024;40(8):864-874
Metal-organic complexes have a long history of clinical application and have shown remarkable efficacy in the treatment of hypertension,skin infections and gastrointestinal diseases.In recent years,the application of metalloids in anti-bacterial infection thera-py and their mechanism of action have been widely studied.In this paper,three commonly used metallodrugs are selected as examples to review the progress and mechanism of metalloids in antibacterial applications,the research of novel metal-based drugs and the metallo-drugs with extracted components of traditional Chinese medicines and their derivatives,and to analyze the potential advantages of metallo-drugs in the field of antibacterial.
2.Application prospect of computer vision technology assisted ultrasonography in diagnosis and treatment of liver diseases
Guoxu FANG ; Wenting XIE ; Kaizhi CHEN ; Siqi CHEN ; Minyong CHEN ; Xiangwen LIAO ; Lina TANG ; Jingfeng LIU
Chinese Journal of Digestive Surgery 2023;22(4):462-467
Ultrasound examination has the advantages of non-radiation, non-invasive, low cost and high efficiency, and is the most commonly used method of liver imaging examination. In recent years, the application of computer vision technology to the intelligent analysis of ultrasound images has become a research hotspot in the field of intelligent healthcare. Through large-scale data training, the intelligent analysis model of ultrasound omics based on machine learning algorithm can assist clinical diagnosis and therapy, and improve the efficiency and accuracy of diagnosis. Based on the literature, the authors summarize the application proprect of computer vision technology assisted ultrasonography in the evaluation of diffuse liver lesions, focal liver lesions, microvascular invasion of liver cancer, postoperative recurrence of liver cancer, and postoperative therapy response to trans-catheter arterial chemoembolization.