Magnetic Resonance Imaging (MRI) can form a three-dimensional positioning anatomical imaging.By comparing the tumor volume and signal intensity changes,there is great value of MRI in the assessment of the efficacy of cervical cancer.With the development of imaging,magnetic resonance diffusion weighted imaging (DWI),magnetic resonance spectroscopy (MRS) can provide qualitative and quantitative information of the cellular level,which reflects changes in the treatment of tumor cells.Magnetic resonance imaging can predict early locally advanced cervical cancer neoadjuvant chemotherapy,thus providing an important basis for individualized treatment of patients.

With the constant deepening of the reform in the health system and the further development of community healthcare services in China, the status and functions of outpatient emergency treatment in hospitals have been put under challenge. Judging from the actual conditions of current China, outpatient emergency treatment in hospitals still occupies a decisive position. It is imperative to transform its functions, enhance pre hospital emergency treatment, supervision of critical cases and healthcare of the general population, broaden programs of medical services, expand channels of economic benefits, and actively adapt to the development in the reform of community healthcare services.

Objective To evaluate the value of imaging means on preoprative diagnosis for patients with malignant obstruction of the biliary and pancreatic ducts.[WT5”HZ]Method [WT5”BZ]44 cases underwent preoperative MR/MRCP/MRA examination. The accurate rate of diagnosis was compared with that derived from B us, CT and ERCP. Results 28 of 44 cases were diagnosed as with pancreatic and periampullary carcinoma, 5 cases as with pancreatic body and tail carcinoma,11 cases as with biliary duct carcinoma. The accurate rates of MR/MRCP/MRA for tumor locating and cause were 100% and 96% respectively. Blood vessel invasion, adjacent organ infiltration and matastasis were detected preoperatively in 17 cases. In contrast, the accurate rate for tumor locating and cause were 82% and 76% with CT, 73% and 68% with B us, 96% and 84% with ERCP. [WT5”HZ]Conclusions [WT5”BZ] MR/ MRCP /MRA combined has advantage over B us, CT and ERCP in preoperative diagnosis especially for detecting organ matastasis and blood vessel infiltration. It has an important value in the establishment of tumor staging and decision making of clinical therapy.

Diffusion-weighted imaging (DWI) is sensitive to identification of cervical lesions and lymph node metastasis.DWI can be used to predict and evaluate the therapeutic effect of cervical cancer.Using magnetic resonance imaging and DWI scans in the process of diagnosis and treatment of cervical cancer,which may contribute to the personalized treatment program and improve prognosis for patients.

Magnetic resonance spectroscopy (MRS) of cervical cancer can detect tumor related specific metabolic compounds such as choline,choline compounds,triglyceride,etc.MRS can be used in identification of benign or malignant lesions of cervix,diagnosis of cervical cancer and monitoring the efficacy of radiotherapy and chemotherapy,etc.It will make for the clinical diagnodis and treatment of cervical cancer.

In order to observe the feature of age-related marrow conversion and maturation of epiphyseal cartilage and analyze the distribution of red and yellow marrow in the proximal femur at STIR MR imaging, STIR and T(1) weighted MR imaging of the proximal femur in 52 subjects, aged 4 months to 25 years old, were retrospectively analyzed for the distribution and appearance of red and yellow marrow. The subjects with no known bone marrow abnormalities were divided into 6 age groups. The signal intensity of the marrow in the proximal epiphysis, proximal metaphysis, proximal diaphysis, distal diaphysis and greater trochanter was compared with the signal intensity and homogeneity of surrounding muscle and fat and graded by two observers. The results showed that the conversion of hematopoietic marrow in the proximal femur followed a well-defined sequence, occurring first in the proximal epiphysis, followed by the distal diaphysis, and then greater trochanter and metaphysis. STIR in combination with T(1)-weighted imaging could display clearly the origin of ossification center and the course of conversion from red to yellow marrow in proximal epiphysis and greater trochanter. STIR imaging showed that the marrow conversion in proximal metaphysic began below epiphyseal plate and intertrochanter. The site of red yellow was distributed in weight-bearing axis by 20 years of age. The marrow conversion of diaphysis was from distal end to proximal end, and the consequence of conversion was that distal diaphysis contained yellow marrow but proximal diaphysis partly red marrow connected with the red marrow of metaphysic. The epiphyseal cartilage had different characters of signal-intensity with age in STIR sequence. The distribution of red marrow in STIR imaging was more close to that of anatomy than T(1)-weighted imaging. It was concluded that STIR could dynamically display the feature of marrow conversion and the development of epiphyseal cartilage and accurately reveal the age-related distribution of red and yellow marrow on STIR imaging in the proximal femur.
Age Factors ; Bone Marrow/*anatomy & histology ; Bone Marrow/physiology ; Epiphyses/anatomy & histology ; Femur/*anatomy & histology ; Image Enhancement/*methods ; Magnetic Resonance Imaging/*methods ; Retrospective Studies ; Young Adult

AIM: To observe the local expression of nuclear factor-?B(NF-?B) in spontaneously hypertensive rat(SHR) kidney and effects of AT1 receptor contagonist valsartan.METHODS: 16 SHRs were randomly divided into two groups: SHR control group and valsartan group.Another 8 WKY rats act as normal control group.Systolic blood pressure(SBP) of SHR was measured at the beginning and the end of 2,4,6 and 8 weeks of intervention treatment.Radioimmunoassay was used to determine the activities of rennin and angiotensin II(AngII).The renal tissue NF-?B protein expression was detected by immunobiochemistry.RESULTS: SBP of SHR was remarkably decreased after valsartan intervention.However,the rennin activities and AngII level in plasma increased in valsartan group.In the renal tissue of SHR,there was remarkably increased in expression of NF-?B protein.Valsartan could significantly reduced NF-?B expression.CONCLUSION: Valsartan can depress NF-?B renal expression in protein level and might benefit hypotension renal function.

Objective To simulate and evaluate the upper and lower limbs posture on rehabilitation devices training with the Computer Aided Tri-Dimensional Interface Application (CATIA) man-machine analysis module. Methods The human body sizes were determined as the 95th percentile Chinese men. Based on the ergonomics analysis of CATIA, three-dimensional human body was constructed in the upper and lower limbs rehabilitation equipment. Virtual human relationship was established. The attitude of the upper and lower limbs in rehabilitation equipment was simulated and evaluated. Results The human limbs model moved in the normal range and the scores were more than 90 which meant comfortable. The forces of various parts of the body was under the stress limit, as well as the force moment. The arm tension was 3-5 points with the rapid upper limb assessment, which meant the rehabilitation equipment was acceptable. Conclusion Rehabilitation robot may be optimized through the model of the human upper extremity stretch domain analysis, body posture assessment, rapid upper limb assessment and biomechanical analysis under CATIA.

BACKGROUND:Studies on the tip position of the conus medullaris in a population have been limited to autopsy and long ago. Therefore, it is necessary to dynamically study the position of conus medullaris (CM) in the Chinese population by magnetic resonance imaging (MRI).OBJECTIVE: To observe the variation in position of the CM in a living population without spinal deformity through MRI. DESIGN: A controlled observation.SETTING: Qingdao Municipal Hospital.PARTICIPANTS: Totally 1199 patients who complained of low back pain and underwent MRI examination in the Department of Radiology of Qingdao Municipal Hospital between October 1993 and December 2006 were recruited in this study. The involved patients, including 765 males and 434 females, were averaged (46±14)years ranging from 5 to 85 years old. Among them, 276 patients suffered from metastatic tumor on spinal vertebrae or trauma of spinal column. Patients with scoliosis or congenital diseases of spinal cord and spinal column were rejected. Another 30 volunteers were recruited via advertisement checked up in the Department of Radiology of Qingdao Municipal Hospital.All the volunteers, including 15 males and 15 females, were averaged (32±8)years, ranging from 19 to 52 years.Written informed consents of detected items were obtained from all the subjects.METHODS: Totally 1199 patients underwent lumbar vertebra MRI scanning by a GE Signa 1.5T supraconduction MRI machine. The tip position of the conus medullaris was observed by spin echo T1 weighted and median sagittal imaging.The MRI machine was located according to its corresponding relationship with vertebral body and intervertebral disc. All the volunteers were given the dynamic research conceming the tip of CM in middle, hyperflexion and hyperextension position.MAIN OUTCOME MEASURES: Dynamic observation of the location of tip of CM in the healthy volunteers and the patients who complained of low back pain.RESULTS: The above 1199 patients who complained of low back pain and 30 healthy volunteers participated in the final analysis. ①The mean conus position of the patients who complained of low back pain was the lower third of L1 (range: middle third of T12 to upper third of L3). The variation in conus positions followed a normal distribution. The conus position in female patients was significantly lower than that of male counterparts (t =18.127,P ＜ 0.01). No significant difference in conus position was seen with increasing age (F =0.530, P ＞ 0.05). ②The tip of the CM did not change in relation to the posterior edge of vertebrae when the spine was in hyperflexion or hyperextension position.However, it got close slightly to the posterior edge of vertebrae when in hyperflexion, and got away slightly from it when in hyperextension.CONCLUSION: The location of tip of CM of our group of population ranges from the middle third of T12 to the upper third of L3, and female population have a much lower conus position than that of male ones.

Objective To investigate the MRI features of cardiac myxoma by correlated with its pathological findings. Methods MRI features of 22 cases of pathologically confirmed cardiac myxomas were retrospectively reviewed. Results Of 22 cases, 21 are solitary, 12 located in left atrium, 6 located in right atrium, 2 located in left ventricle and 1 located in right ventricle. The other one occupied multiple chambers. MRI: 19 are heterogeneous and 3 are homogeneous. Cine-MRI: 18 attach to the endocardium with a pedunculated stalk and 4 are sessile and with a broad attachment. Thirteen cases had secondary valve insufficience or stenosis. Nine have compromised cardiac function. Nineteen cases demonstrated mild to moderate heterogeneous enhancement after Gd-DTPA administration and 3 ease showed no enhancement. Four cases had gadolinium first-pass perfusion study and showed a slow and continuous increasing time-intensity, lower than normal myocardium. The pedicles and wall showed delay enhancement. Pathologic findings: 21 are oval and lobalar configuration, 1 is grape-like. Ten cases had fresh hemorrhage and 5 had chronic hemorrhage. Fourteen had necrosis , 2 had cystic change and 4 had calcification. Blood vessels or inflanmmtory cells could be detected in 19 cases. Conclusions MRI can evaluate the size, location, morphology, especially the vascularity, histologic features and cardiac function of cardiac myxomas.