1.Research Progress in Decolorization Methods for Polysaccharide Extracts of Traditional Chinese Medicines
Mingquan CHANG ; Xiangqian CHE ; Rongjing JIANG
China Pharmacist 2017;20(5):893-896
The relevant literatures were looked up, summarized, classified and reviewed, and the research progress in decolorization methods for the extracts of traditional Chinese medicines containing polysaccharide was introduced.The decolorization methods commonly used for polysaccharide extracts of traditional Chinese medicines were activated carbon decolorization, macroporous resin decolorization, hydrogen peroxide decolorization, sodium hypochlorite decolorization and so on.According to the combination form of polysaccharide and pigment, the suitable decolorization method should be selected to improve the purity of polysaccharide and the quality of related preparations, which shows guidance effect on fine finishing of traditional Chinese medicines.
2.Protective effect of safflower solution on warm ischemia reperfusion injury of liver
Xin QI ; Xiangqian CHE ; Chao WANG ; Zhijun HE
Chinese Journal of General Surgery 2001;0(07):-
Objective To study the protective effect and mechanism of safflower solution on warm ischemia reperfusion injury(IRI) of liver in rats.Methods Male Sprague-Dawley rats were randomly divided as 4 groups: Group S(sham group);group I/R(IRI group);group IPC(ischemic preconditioning group);group SPC(safflower solution preconditioning group).The rats were sacrificed at 24 h after reperfusion,serum levels of ALT and AST were measured and HE staining of liver tissues were made to detect rat liver histological changes and grade liver IRI(Suzuki score);apoptosis were monitored by TUNEL;TNF-?,MIP-2 and ICAM-1 mRNA of liver were measured by RT-PCR;NF-?B gene products of liver were detected by Western blotting.The mean value of all the assay tests was compared.Results After 24 h reperfusion,compared with group I/R,the liver function(ALT and AST) in group SPC and group IPC was significantly improved(P
3.Optimization of Activated Carbon Decolorization Technology for Bletilla Striata Polysaccharide by Orthogonal Test
Xiangqian CHE ; Mingquan CHANG ; Lin CHEN ; Fang CHEN ; Rongjing JIANG
China Pharmacist 2017;20(8):1370-1373
Objective: To optimize the decolorization technology of activated carbon for the plant pigment in Bletilla striata polysaccharide.Methods: Using L 9 (3 4) orthogonal test with activated carbon as the decolorizer, the amount of activated carbon, decolorization temperature, decolorization liquid pH and decolorization time were investigated.The decolorization rate and polysaccharide retention rate were investigated.The decolorization rate and polysaccharide retention rate were taken as the indices.Results: The optimum decolorization technology was as follows: the amount of activated carbon was 1.0%, the decolorization temperature was 40 ℃, the pH value was 5 and the decolorization time was 30 min.Under those conditions, the decolorization rate of Bletilla striata polysaccharide was 91.3% and the retention rate of polysaccharide was 80.6%.Conclusion: The selected decolorization technology of activated carbon can make Bletilla striata polysaccharide get the best decolorizing effect.
4.Research on the rationalization of doctor-patient communication behavior from the perspective of communicative action theory:a case study of the documentary Chinese Doctors
Chinese Medical Ethics 2024;37(10):1181-1188
Doctor-patient communication is not only a part of medical behavior,but also an important part of social communicative action.Starting from the perspective of the core category of communication action theory,namely the rationalization of communication behavior,this paper investigated the elements of rationalization in the doctor-patient communication behavior in the documentary Chinese Doctors.It was found that reasonable doctor-patient communication was based on the intersubjectivity between doctors and patients,with the medical and patient subjects engaging in equal interaction around illness,diagnosis and treatment,and other objects;doctor-patient speech should follow the requirements for communicative validity,which require authenticity,correctness,and sincerity as conditions;doctor-patient communication should take the ideal speech situation as a way to achieve free and rational dialogue,and ultimately should take understanding and consensus as orientation to build a harmonious doctor-patient communication relationship.