Objective To compare different treatment methods for patients with gastric calculi and provide data support for clinical treatment.Methods A total of 197 patients diagnosed with gastric calculi by gastroscopy at the General Hospital of Ningxia Medical University and Cardio-Cerebrovascular Disease Hospital of General Hospital of Ningxia Medical University from July 2013 to January 2024 were enrolled.The study collected general information and other data of the patients,and divided them into groups based on the selected treatment method using a real-world research approach.The subjects were divided into four groups:drug conservative treatment group,endoscopic homemade snare treatment group,disposable snare treatment group,and stone fragmentation treatment group.Statistical analysis was performed using one-way analysis of variance.Results Gastric calculi were more common in men,with an average age of(55.45±14.21).85.3%of the patients had a history of eating persimmon,86.3%had ulcers,and 65.9%were located in the gastric angle.The self-made snare group had the lowest treatment cost,while the stone fragmentation group had the highest.There was no significant difference in the remission time of clinical symptoms among the three endoscopic treatment methods.The self-made snare had the highest patient satisfaction,but the drug combined with carbonated beverage group had the longest remission time of clinical symptoms and the lowest patient satisfaction.The frequency and duration of endoscopic treatment of dark green gastric stones were significantly higher than those of mottled and golden yellow gastric stones.Conclusion When treating patients with gastric stones,it is important to consider the size and color of the stone,as well as the patient's preferences.Patients should be fully informed about their condition and the advantages of different treatments.For patients with larger stones(about 5 cm),endoscopic snare treatment is recommended as the first choice.

Objective:To evaluate the effects of different intervention measures on duration of mechanical ventilation and the length of intensive care unit (ICU) stay in critically ill patients using network Meta-analysis.Methods:Randomized controlled trial (RCT) on the effects of different intervention measures on duration of mechanical ventilation and the length of ICU stay in critically ill patients were systematically searched in PubMed, Embase, China Biomedical Literature Database, CNKI, and other databases. The search time limit was from the establishment of the database to November 2023. Literature screening, quality assessment, and data extraction were independently conducted by two researchers. Network Meta-analysis was employed to assess the effects of each intervention on duration of mechanical ventilation and the length of ICU stay, and funnel plots were generated.Results:A total of 37 RCTs were included, involving 3?977 severe patients, 2?041 in the intervention group and 1?936 in the control group. Thirteen types of interventions were analyzed, including usual care (UC), early activity (EA), early comprehensive rehabilitation (ECR), early pulmonary rehabilitation (EPR), cluster intervention strategy (CS), sedation, analgesia and cluster nursing (SACN), music therapy (MT), neuromuscular electrical stimulation (NMES), modified education and visitation (MV), virtual reality (VR), auricular point sticking (APS), acupoint acupuncture (AA), and concerted intervention (COR). Network Meta-analysis showed that MV significantly better than COR [standardized mean difference ( SMD) = -2.35, 95% confidence interval (95% CI) was -4.30 to -0.39], EPR ( SMD = -2.59, 95% CI was -4.81 to -0.37), and UC ( SMD = -4.10, 95% CI was -5.71 to -2.49) in improving duration of mechanical ventilation in critically ill patients. COR was significantly better than UC in shortened length of ICU stay ( SMD = -5.72, 95% CI was -10.07 to -1.37). The efficacy ranking results showed that for duration of mechanical ventilation, the surface under the cumulative ranking curve (SUCRA) was highest for MV (85.4%) and EA (85.4%), followed by AA (74.9%), NMES (63.1%), ECR (51.7%), CS (48.8%), SACN (34.3%), COR (29.4%), EPR (26.1%), and UC (0.7%). For the length of ICU stay, COR had the highest SUCRA (82.3%), followed by APS (79.7%), MV (77.7%), EPR (68.0%), NMES (57.6%), CS (54.4%), ECR (51.1%), SACN (41.9%), MT (39.8%), EA (39.3%), AA (33.0%), VR (15.4%), and UC (9.8%). The funnel plot results of ICU stay showed that the publication bias between studies were relatively small. Conclusions:MV and COR appear to be effective interventions for reducing mechanical ventilation time and ICU stay in critically ill patients. However, due to the number and quality of included studies, these findings require confirmation through additional high-quality research.

Objective:To evaluate the safety and clinical efficacy of hypofractionated radiotherapy (HFRT) at 36.5 Gy in 10 fractions for the chest wall and reginal lymph nodes following modified radical mastectomy for breast cancer.Methods:This was a prospective, single-arm, phase Ⅱ clinical study. A total of 85 patients who received HFRT at 36.5 Gy in 10 fractions to the chest wall ± supraclavicular region following modified radical mastectomy for locally advanced breast cancer from March 2014 to December 2015 were included. The primary endpoint was radiotherapy toxicities. The secondary endpoints were locoregional failure-free survival (LRFFS), disease-free survival (DFS), and overall survival (OS).Results:The median follow-up period was 98 (94.0-109.0) months. Radiotherapy toxicities were mild. The incidence rates of grade 1 acute cutaneous and pulmonary toxicities were 52.9% and 40%, and those of grade 1 late cutaneous, pulmonary, and cardiac toxicities and upper extremity edema were 10.6%, 29.4%, 2.4%, and 21.2%, respectively. Only 1 (1.2%) patient suffered from grade 2 radiation-induced brachial plexus injury. Of the 85 patients, one patient had regional recurrence (supraclavicular lymph nodes), six patients had distant metastasis, and six patients died of breast cancer. The 9-year LRFFS, DFS, and OS were 97.7%, 91.8%, and 92.8%, respectively.Conclusions:HFRT at 36.5 Gy in 10 fractions following modified radical mastectomy for breast cancer is associated with mild toxicities. A phase Ⅲ study is necessary for validating HFRT's clinical efficacy.

OBJECTIVETo understand the prevalence of myopia in primary and middle school students in 6 provinces and the possible influencing factors.

METHODSPrimary and middle school students were selected through multistage cluster sampling in 60 primary and middle schools in 6 provinces in China. The questionnaire survey and eyesight test were conducted among all the students selected according to the national student's physique and health survey protocol. Pearson chi-square test and binary multivariate logistic regression analysis were done to identify the influencing factors for myopia in students.

RESULTSThe prevalence of myopia among primary and middle school students surveyed was 55.7%, the gender specific difference was statistically significant (59.7% for girls, 51.9% for boys) (P<0.01). The prevalence of myopia increased with age obviously. The prevalence was 35.8% in age group 6-8 years, 58.9% in age group 10-12 years, 73.4% in age group 13-15 years and 81.2% in age group 16-18 years, the differences were statistically significant (P<0.001). Single factor and multivariate analysis showed that parents' myopia, distance between computer screen and eyes, distance less than 30 cm between eyes and book while reading, distance less than 10 cm between chest and the table edge while studying, distance less than 3 cm between fingers and pen tip, sleep time, average outdoor activity time during last week, school sport activities in the afternoon, the size of television set at home, time spent on watching TV and playing computer were the influencing factors for myopia.

CONCLUSIONSThe prevalence of myopia is till high in primary and middle school students. Myopia is associated with both genetic factors and individual eye health related behaviors.

Adolescent ; Child ; China ; epidemiology ; Female ; Health Behavior ; Health Surveys ; Humans ; Logistic Models ; Male ; Multivariate Analysis ; Myopia ; epidemiology ; Parents ; Prevalence ; Schools ; Sleep ; Students ; Surveys and Questionnaires

To explore the status of two-week illness in primary and secondary students and to provide the basis for rationally distributing heath resources in primary and secondary schools.
 Methods: Stratified cluster sampling method was used to select 6 744 primary and secondary students aged from 9.0-16.9 years, and the name or symptoms of two-week illness, frequencies, medical expenses and days of sick leave were surveyed by using the self-made questionnaires.
 Results: Respiratory system disease (73.6%) and digestive system diseases (13.2%) were the major two-week illness. When they were ill, 58.9% students went to hospital, 39.9% took medicine by themselves, and 1.2% received non-treatment. The two-week morbidity, sick frequencies, average medical expenses per time and days of sick leave were 12.6%, (1.34±0.81) times, 10.0 yuan, and (0.39±0.98) days, respectively. The two-week sick frequencies, average medical expenses per time and days of sick leave among primary or secondary students were (1.37±0.87) or (1.26±0.69) times, 12.0 or 9.0 yuan, and (0.44±1.14) or (0.30±0.55) days, respectively. There was a positive correlation between two week sick frequencies and medical fees per time, or days of sick leave (r=0.301, r=0.275 for primary students, respectively, P<0.01; r=0.334, r=0.290 for secondary students, respectively, P<0.01). The positive correlation between medical fees per time and days of sick leave was also found (r=0.312, r=0.343 for primary students and secondary students, respectively, P<0.01).
 Conclusion: Characteristics of two-week illness among primary and secondary students possess common symptoms, frequent, low medical expenses per time. The frequencies, medical expenses and days of sick leave in primary students were increased compared with that in secondary students.
Adolescent ; Child ; Digestive System Diseases ; epidemiology ; therapy ; Fees, Medical ; statistics & numerical data ; Female ; Humans ; Male ; Respiratory Tract Diseases ; epidemiology ; therapy ; Schools ; Sick Leave ; statistics & numerical data ; Students ; Surveys and Questionnaires

OBJECTIVETo understand the mediating effect of blood lipids on the correlation between body fat and blood pressure among overweight adults.

METHODSOverweight and obese subjects aged 20-55 years who had lived in Beijing for at least 1 year were recruited in this study, Body mass index (BMI) was used as a screening indicators. The percentage of body fat (PBF) was measured for the subjects by using dual energy X-ray absorptiometry (DXA). Mediating effect analysis was conducted to analyze the mediating effect of blood lipids on correlation between PBF and systolic blood pressure (SBP) as well as diastolic blood pressure (DBP).

RESULTSAfter adjusting for age, PBF was positively correlated with SBP and DBP in both males (β = 0.208 3, β = 0.205 2, P < 0.001) and females (β = 0.188 4, β = 0.209 6, P < 0.001). In male subgroup, PBF was negatively correlated with HDL-C level, but positively correlated with LDL-C level (β = -0.142 2, P < 0.01 and β = 0.180 5, P < 0.001), while in female subgroup, PBF was positively correlated with both TC level and LDL-C level (β = 0.172 1, P < 0.001 and β = 0.233 5, P < 0.001). With PBF controlled, TC and TG levels were positively correlated with DBP in both males and females (β = 0.095 6, 0.090 5 for males, β = 0.117 6, 0.083 1 for females, P < 0.05), and TG level was positively correlated with SBP in females (β = 0.127 2, P < 0.001). Further analysis indicated there was a significant mediating effect of LDL-C on correlation between PBF and DBP in females, with the mediating effect value of 0.019 4 (P < 0.05). The ratio of mediating effect was 9.26%.

CONCLUSIONPBF was positively correlated with blood pressure, but blood lipids had no mediating effect on the correlation between PBF and blood pressure in males, while LDL-C level had mediating effect on PBF and blood pressure in females.

Adipose Tissue ; Adult ; Beijing ; Blood Pressure ; Body Mass Index ; Female ; Humans ; Lipids ; blood ; Male ; Middle Aged ; Obesity ; Overweight ; Sex Factors ; Young Adult

Objective:To analyze the awareness rate of obesity risk factors among children and adoles-cents, and to provide the basis for preventing their obesity. Methods: The students selected by using stratified cluster sampling method, were measured for the body height, weight, and waist circumference, and were surveyed for the awareness rate of obesity risk factors by using the questionnaire. The distribu-tion characteristics of awareness on obesity risk factors were analyzed. Results: The awareness rate of obesity risk factors was 74 . 1%, and there was no significant difference on the awareness rate of obesity risk factors between the males [71. 2% (247/347)] and females [77. 2% (257/333)], the abdominal obesity students [73. 5% (202/275)] and non-abdominal obesity students [74. 6% (302/405)], the overall obesity students [74. 3% (185/249)] and non-overall obesity students [74. 0% (319/431)], re-spectively. However, the awareness rate of obesity risk factors among the primary school students was 81. 9% (272/332) that was higher than that of the middle school students [66. 7% (232/348)] (P<0. 05). Compared with the primary school students, the non-awareness risk of obesity risk factors would in-crease among the middle school students (OR=2. 23, P<0. 05). Conclusion:The overall awareness rate of obesity risk factors is not high among children and adolescents, especially among middle school students.

OBJECTIVETo analyze the influence factors of body image dissatisfaction among children and adolescents with normal weight.

METHODSThe primary and middle school students who were selected from Changping district of Bejing city using the stratified cluster sampling method were measured body height, weight, and waist circumference. Body image cognitive attitude of students or their parents was surveyed using 'Ma figural shape'. The cognitive attitude of obesity risk factors was surveyed by self-designed questionnaires. The students with normal weight were selected according to 'reference norm for screening overweight and obesity in Chinese children and adolescents (WGOC) in 2005' and 'reference norm for screening underweight in Chinese children and adolescents aged 6-19 years'. The association between body image dissatisfaction and cognitive attitude of obesity risk factors was analyzed for each gender.

RESULTSThe study validly surveyed and measured 680 students, and there were 36.6% (249/680) students with overweight or obesity, 4.0% (27/680) students with underweight, and 59.4% (404/680) students with normal weight. Prevalence of body image satisfaction, expecting to be thinner, and to be fatter in students with normal weight was 32.7% (132/404), 35.1% (142/404), and 32.2% (130/404), respectively. The prevalence of expecting to be thinner in females and middle students was higher than that in males and primary students (46.4% (102/220) vs 21.8% (40/184)), (39.8% (88/221) vs 29.5% (54/183)), respectively; χ² values were 26.65 and 4.67 respectively (P < 0.05). The prevalence of expecting to be fatter in males was higher than that in females ((42.9% (79/184) vs 23.2% (51/220)) (χ² = 17.91, P < 0.001). The concordance ratio on body image cognitive attitude between students and their parent was 60.4% (244/404), and the consistency coefficient was 0.41 (P < 0.001). The factors including parents expecting their children to be thinner, the negative attitude on less drinking sugary beverages and having breakfast per day might increase the risks of children expecting to be thinner in males, the OR (95% CI) value were 5.20 (1.51-17.89), 3.43 (1.11-10.59), and 6.53(1.14-37.58), respectively. The parents expecting their children to be fatter might increase the risk of children expecting to be fatter in males, the OR (95% CI) value were 7.57 (3.47-16.52). The factors including parents expecting their children to be thinner, and the positive attitude on less eating high calorie snacks might increase the risk of children expecting to be thinner in females, the OR (95% CI) value were 65.74 (8.45-511.21) and 3.03 (1.01-9.09), respectively. The parents expecting their children to be thinner or fatter might increase the risk of children expecting to be fatter in females, the OR (95% CI) value were 17.38 (1.53-197.74) and 9.64 (3.98-23.35), respectively.

CONCLUSIONThe prevalence of body image dissatisfaction among students with normal weight was high, and the concordance ratio on body image cognitive attitude between themselves and their parents was low. Guiding students to have the correct cognitive attitude on less drinking sugary beverages, having breakfast per day, and less eating high calorie snacks may be conducive to prevent body image dissatisfaction.

Adolescent ; Asian Continental Ancestry Group ; Body Image ; Body Mass Index ; Body Weight ; Child ; Female ; Food Preferences ; Humans ; Male ; Obesity ; Overweight ; Personal Satisfaction ; Prevalence ; Risk Factors ; Students ; Surveys and Questionnaires ; Young Adult

OBJECTIVETo analyze the differences in anthropometric measurements between Mongolia and Han girls and understand the characteristics of their physical development in two ethnic groups.

METHODSThe data on anthropometric measurements of Mongolia and Han girls aged 9-17 years in Inner Mongolia were obtained from the Chinese National Survey on Student's Constitution and Health (CNSSCH) in 2010, and the data included body height, sitting height, chest circumference, weight, triceps skinfold thickness (TST), scapular skinfold thickness (SST), abdominal skinfold thickness (AST), and having menarche or not. The girls were divided into two groups according to having menarche or not, and the differences in anthropometric measurements between Mongolia and Han girls were analyzed for the two groups, respectively.

RESULTSThe proportions of Mongolia girls (9-17 years) who have experienced menarche was higher than that of Han girls (67.6%,1 049/1 553) vs (62.9%,1 837/2 922) (χ² = 9.17, P = 0.002). In girls without menarche (9-14 years), sitting height, AST, and BMI in Mongolia girls was 0.5 cm, 1.6 mm, and 0.4 kg/m², respectively, which were higher than those in Han girls (all P < 0.05). In girls who have experienced menarche (11-17 years), height and SST in Han girls was 0.8 cm, and 1.0 mm, respectively, which were higher than those in Mongolia girls (all P values < 0.01); TST, AST and BMI in Mongolia girls were 0.9 mm, 2.9 mm, and 0.3 kg/m², respectively, which were higher than those in Han girls (all P values < 0.05), respectively.

CONCLUSIONBody AST and BMI in Mongolia girls are higher than those in Han girls, while body height in Han girls is better than that in Mongolia girls after menarche. The differences of physical development between Mongolia girls and Han girls might be different before and after experiencing menarche.

Adolescent ; Anthropometry ; Asian Continental Ancestry Group ; Body Height ; Body Mass Index ; Body Weight ; Body Weights and Measures ; Child ; China ; Female ; Humans ; Menarche ; Skinfold Thickness

Objective To understand the mediating effect of blood lipids on the correlation between body fat and blood pressure among overweight adults. Methods Overweight and obese subjects aged 20-55 years who had lived in Beijing for at least 1 year were recruited in this study, Body mass index(BMI)was used as a screening indicators. The percentage of body fat(PBF)was measured for the subjects by using dual energy X-ray absorptiometry(DXA). Mediating effect analysis was conducted to analyze the mediating effect of blood lipids on correlation between PBF and systolic blood pressure(SBP)as well as diastolic blood pressure(DBP). Results After adjusting for age,PBF was positively correlated with SBP and DBP in both males(β=0.208 3,β=0.205 2, P<0.001)and females(β=0.188 4,β=0.209 6,P<0.001). In male subgroup,PBF was negatively correlated with HDL-C level,but positively correlated with LDL-C level(β=-0.142 2,P<0.01 andβ=0.180 5,P<0.001),while in female subgroup,PBF was positively correlated with both TC level and LDL-C level(β=0.172 1,P<0.001 and β=0.233 5,P<0.001). With PBF controlled,TC and TG levels were positively correlated with DBP in both males and females(β=0.095 6,0.090 5 for males,β=0.117 6,0.083 1 for females,P<0.05),and TG level was positively correlated with SBP in females(β=0.127 2,P<0.001). Further analysis indicated there was a significant mediating effect of LDL-C on correlation between PBF and DBP in females,with the mediating effect value of 0.019 4 (P<0.05). The ratio of mediating effect was 9.26%. Conclusion PBF was positively correlated with blood pressure,but blood lipids had no mediating effect on the correlation between PBF and blood pressure in males,while LDL-C level had mediating effect on PBF and blood pressure in females.