1.Superior horn of thyroid cartilage dysplasia in 1 case.
Xiangguo CUI ; Lei SHI ; Huaian YANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(14):1087-1087
The external stimuli and other reasons may result in hyperplasia and abnormal angle of the upper corner of the thyroid cartilage. The upper corner of the thyroid cartilage has anatomical variations. To oppression stimulate carotid artery, cervical sympathetic dry section and so on, could causing pharyngeal foreign body sensation and sore throat. By surgical removal of the thyroid cartilage hyperplasia upper corner, postoperative symptoms would be resolved.
Humans
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Hyperplasia
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Male
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Middle Aged
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Thyroid Cartilage
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pathology
2.Efficacy of percutaneous transhepatic variceal embolization with TH glue for large gastric fundal variceal bleeding
Jinhua HU ; Xiangguo TIAN ; Guangchuan WANG ; Yongjun SHI ; Junyong ZHANG ; Fuli LIU ; Yi CUI ; Chunqing ZHANG
Chinese Journal of Digestive Endoscopy 2012;29(10):545-548
Objective To investigate the efficacy of percutaneous transhepatic variceal embolization (PTVE) with Cyanoacrylate (TH glue) in treating large gastric fundal variceal bleeding.Methods PTVE was performed on 24 patients with TH glue injected into the main stem of left gastric vein and its fundic branches.The degree of varices in gastric fundus,rebleeding rate and survival rate after the procedure were compared with those before.Results Varices in gastric fundus were all embolized successfully with TH glue.The diameter of varices was reduced to below 5mm or disappeared in 20 patients (83.3%),and reduced to 5-10mm in the other 4 ( 16.7% ) During the follow-up period of 3-36 months(mean 16.6 months),the rebleeding rate and mortality were 12.5 % ( 3/24 ),and 12.5 % (3/24),respectively.One patient died of liver cancer,and two others died of chronic liver failure.Conclusion PTVE with TH glue is of ideal therapeutic effect to block the feeding veins of large gastric fundal varices.
3.Clinicopathological features and prognostic significance of human epidermal growth factor receptor 2 in gastric carcinoma
Mengying KOU ; Zhaoyang WANG ; Richang DU ; Tao ZHANG ; Min FENG ; Lingli DENG ; Xiangguo ZHANG ; Chunlan ZHONG ; Lei CUI ; Jiaocheng WANG
Cancer Research and Clinic 2016;28(7):441-446
Objective To explore the clinicopathological features and prognostic significance of human epidermal growth factor receptor 2 (HER2) in gastric carcinoma. Methods Pathological data of 127 patients with gastric carcinoma were retrospectively analyzed. HER2 expressions of all patients were detected by immunohistochemistry (IHC). 119 (93.7 %) patients were undergone R0 dissection and 123 (96.9 %) cases received D2 lymph nodes dissection. 51 (40.2 %) patients received adjuvant chemotherapy. The proportional differences of clinicopathological features for patients between HER2-positive and HER2-negative were compared, including the patients' survival. Results HER2 overexpression rate was 8.7 % (11/127) in gastric carcinoma patients. For the patients with HER2-positive and HER-negative, the lymph node metastasis rates were 100.0 % (11/11) and 81.9 % (95/116), respectively (P= 0.041). The 3-year overall survival (OS) rates for HER2-positive and HER2- negative patients with gastric carcinoma were 32.7 % and 42.9 % (P=0.413), and the 5-year progression free survival (PFS) rates were 27.3 % and 42.2 % (P = 0.354), respectively. Among patients with HER2-negative, 3-year OS rate for patients with surgery plus adjuvant chemotherapy was 55.3%, compared with 35.4%for patients with surgery alone (P=0.015), and the 3-year PFS rates were 53.3 % and 35.3 % (P= 0.038), respectively. Among patients with HER2-positive patients, 3-year OS rate for patients with surgery plus adjuvant chemotherapy was 0, compared with 75.0%for patients with surgery alone (P=0.002), and the 3-year PFS rates were 0 and 60.0% (P=0.004). Conclusions HER2 is expressed in gastric carcinoma tissue, related to lymph node metastasis. HER2 status are not correlated with the prognosis for gastric carcinoma patients, however, it is likely to be a predictive marker for adjuvant treatment after surgery for patients with gastric carcinoma.
4.Research on failure reasons of surgical treatment of obstructive sleep apnea hypopnea syndrome and reoperation method.
Chen ZHAO ; Xiaotian LI ; Yaqi LIU ; Xiangguo CUI ; Zhongliang FU ; Huaian YANG ; Xuejun JIANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(12):626-628
OBJECTIVE:
To analyze failure reasons of surgical treatment of obstructive sleep apnea hypopnea syndrome (OSAHS), and explore the methods of reoperation.
METHOD:
By selecting 27 patients, who accepted surgical treatment for OSAHS and recurred, we analyzed failure reasons and obstructive location by apneagraph, nasopharyngeal 3D-CT, electronic nasopharynlaryngoscope. Among them, 14 patients accepted reoperation, such as uvulopalatopharyngoplasty (UPPP), nasoendoscopic surgery, adenoidectomy, partial glossectomy, tracheotomy were applied matching to differential obstructive location. AHI, lowest SaO2, Epworth sleepiness scale (ESS), complication were recorded after 6 months.
RESULT:
After 6 months, their AHI decreased from 48.19 +/- 13.11 to 11.32 +/- 4. 42, ESS scores decreased from 12.93 +/- 4.60 to 4.93 +/- 1.44, P<0.05. Two of the 14 patients were cured, while the other 12 were efficient. No complications were observed.
CONCLUSION
Obstructive location judgement and proper surgical operation are the keys of the treatment. Preoperative AG sleep monitoring, nasopharyngeal 3D CT, electronic nasopharynlaryngoscope examination for determining blocking plane, the decision of surgery which is significant.
Adult
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Female
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Humans
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Male
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Palate
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surgery
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Palate, Soft
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surgery
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Pharynx
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surgery
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Recurrence
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Reoperation
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Sleep Apnea, Obstructive
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prevention & control
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surgery
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Treatment Outcome
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Uvula
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surgery