1.An experimental study on protective effect of extracellulsr ATP to motorneurons on spinal cord after brachial plexus avulsion
Fuchun LU ; Shuanke WANG ; Xiangdong YUN
Chinese Journal of Microsurgery 2008;31(6):424-427
Objective To investigate the protective effect of extracellular ATP on motoneurons of spinal anterior horn from spinal root avulsion induced cell injurey. Methods Thirty-six Wister rats were randomized into 2 groups: single root avulsion and root avulsion with ATP. The left C5-C8 nerve roots were avulsed, the experiment group was gioven extracellular ATP (2 mg/kg) 0.4 ml by intraperitoneal injection and control group physiological saline water was gioven 0.4ml as the same method, all one time daily, contin-ue injection ATP or saline water 2 weeks. At 2,4 and 6 week postoperatively, C5-C8 spinal cord was har-vested after the rats were executed. The change of nitric oxide synthase (NOS) and neurofilament protein (NF-200) were observed after histochemistrical examination. Results At 2、4 and 6 week postoperatively, the survival of motorneurons in the spinal anterior was 80.48%, 73.55% and 53.43% in experiment group, was 68.90%、63.58% and 37.72% in control group;compare experiment group with control group, the le-don-induced motomeurons death in the spinal anterior bern was decreased by 11.58%、9.78% and 15.71% respectively (P < 0.01) ; the activity changes of NOS expression rate was 17.85% ,40.20% and 18.03% in experiment group, was 25.53%,53.88% and 25.58% in control group, compare experiment group with con-trol group, the activity changes of NOS expression rate was decreased by 7.68% (P < 0.01), 13.68% and 7.55% (P < 0.05) respectively. The motoneurons expressed NF-200 in the experiment group was larger than the control group, there was significant difference was found between the control group and the experiment group. Conclusion ATP might play certain protective role in survival of motoneurous after spinal root avulsion.
2.Application of Pemberton's osteotomy in the treatment of congenital hip dislocation of chidren
Xu WANG ; Ping DONG ; Xiangdong YUN
Orthopedic Journal of China 2006;0(07):-
[Objective]To summarize clinical experience of Pemberton's ilium osteotomy in developing hip dislocation and emphasize the combined and individual principles in the clinical practice. [Methods]From February 1996 to April 2007,26 patients(aged 3 to 10 years) with 28 hips were operated on together with soft tissue solution,a pericapsular osteotomy of the ilium (Pemberton) and an optional femoral rotational,shortening or varus osteotomy of the proximal femur. Pre-and post-operative indexes including those of AI angle,CE angle and deep of acetabulum were compared. According to Severin's classification and McKay clinical curative effect evaluation critera,these indexes were evaluated.[Results]According to the Severin's classification,the results were rated as 64.3% excellent,28.6% good and 7.1% fair.On the McKay's critera ,the functional results were graded as 50.0% excellent,35.8% good,7.1% fair and 7.1% poor. On the whole,the radiographic evaluation was superior to that of the functional results.[Conclusion]The Pemberton's osteotomy is safe and effective.The combined surgical treatment can improve the success rate and decrease complications.
3.Research on the analysis and evaluation of uncertainty of spectrophotometer detection device
Xiangdong LI ; Li CUI ; Qinghui YUN
China Medical Equipment 2016;(2):22-24
Objective:To analyze and evaluate the uncertainty of spectrophotometer detection device, stability, repeat-ability, the accuracy of the standard testing devices for the detection of spectrophotometer in laboratory.Methods: To calculate the uncertainty of measurement of standard gear, stability, repeat ability for evaluating the accuracy of the standard device.Results: According to the national standard, through analysis and calculation, the veracity and reliability of standard device were proved.Conclusion: Through analysis and evaluation, the uncertainty of verification device of spectrophotometer met the requirement of value. The repeatability and stability complied with the requirement of standard establishment. It can use in detection spectrophotometer, and make sure the results accurate and reliable.
4.The research of improvement on information management system of medical devices in use
Li CUI ; Xiangdong LI ; Qinghui YUN
China Medical Equipment 2016;13(9):111-113
Objective: The system of quality control management of medical equipment is an important management means to maintain medical security, achieve quality control management by the information technology, and it can quickly improve the efficiency of management and increase the effectiveness of the management. Methods: Using the tools of B/S of three layer architecture technology, the management of medical device adverse event, assessment of medical equipment, management of medical equipment scrap, management of medical metrology certificate, and other functions are developed. Results:The adverse events, examine, scrap, certificate management, and other functions are designed through the software, the quality of the equipment is mastered in time through different testing cycle of data comparison, so that the related departments can take preventive maintenance to make the equipment in good state. Conclusion: The informational system of quality control management is used to promote the modernization of medical management and guarantee effectively the quality and safety of medical equipment.
5.Preliminary study of P300 topography mapping in patients with closed craniocerebral trauma
Xiangdong ZHAO ; Yun LING ; Meilian ZHANG
Journal of Clinical Neurology 1988;0(02):-
Objective To investigate changes of the visual P300 topography mapping in patients with closed craniocerebral trauma.Methods The visual P300 topography mapping was recorded from 103 patients with closed craniocerebral trauma and 66 normal subjects with a medicide-03E brain evoked potential instrument. Results The P300 latency in patient group was significantly prolonged as compared with the control group ( P
6.Discussion on comprehensive evaluation for medical equipment of the quality control
Xiangdong LI ; Li CUI ; Qinghui YUN
China Medical Equipment 2014;(2):67-68,69
Objective:According the review of three grade hospital, it is analysis the problems that evaluation experts pointed out. We can take effective measures and improve insufficient of control management to increase management efficiency. Methods: We can perfect quality control management system, improve the assessment mechanism, establishment of information management system to strengthen the quality control management of medical equipment. Results:After implementation of improvement measures, improve the management mechanism, the quality control management come into the information, scientific management stage. Conclusion:Through the review, we can promote construction by evaluation;the quality control and management work are improved. We can ensure the quality and safety of medical equipment, which can give full play to efficiency, better services for patients.
7.Research on designing of B/S structure-based measurement and quality control systems of equipment department
Li CUI ; Xiangdong LI ; Qinghui YUN
China Medical Equipment 2015;(7):10-12,13
Objective:To design the medical equipment quality control management system and it can improve the efficiency of management, and provide data of quality evaluation of equipment for purchasing.Methods: Quality control management system adopts three layer architecture technology of B/S and publishing tools of IIS, it can implement the various functions of quality control in the management.Results: The system realized some function, like data entry, modify, query and extracting features, et al. The system can evaluate the performance of the equipment through the data analysis. So the maintenance department can preventive maintenance through the data. The equipment is insured in good condition, the purchasing department choose stability equipment in clinical. Conclusion: Quality control management system can evaluate the quality of the medical equipment through the testing data, at the same time the system can intuitive understanding controlled state of the medical equipment for managers, the mangers can take the effective measures to ensure the safety of the medical equipment quality through the system.
8.Equipment department management information system based on B/S architecture:consumables supermarket management
Xiangdong LI ; Qinghui YUN ; Yongmei SUN ; Hu JIN
Chinese Medical Equipment Journal 2015;(9):129-132
To establish a consumables supermarket management system to realize the informatized management of the consumables supermarket. The system used SOA as the main architecture, and IIS manager as the pub-lishing tool. The system had the workload, materials and financial resources decreased while the efficiency in-creased, and made the supervisor master the sale information timely. Consumables supermarket informatized management may decrease the hospital's needs for current capital as well as the links, while increase the hospital effi-ciency greatly.
9.Equipment department management information system based on B/S architecture:purchase process management
Xiangdong LI ; Qinghui YUN ; Ye DUAN ; Hu JIN
Chinese Medical Equipment Journal 2015;36(5):134-137
Objective To develop an equipment purchase process management module based on B/S architecture to standardize hospital equipment purchase process and promote hospital informatization. Methods Service-oriented architecture (SOA) was adopted as the main architecture, and internet information service (IIS) manager was used as the publishing tool.Results All the departments could visit the system through hospital intranet and perform on-line equipment purchase and inquiry for progress.Conclusion The system facilitates the inquiry of all departments for the progress of equipment purchase, and standardizes and optimizes the equipment purchase process.
10.The role of actigraphy in monitoring sleep and sleep disorders.
Dexi WANG ; Zongping ZHANG ; Hong LIU ; Yun LI ; Fei LEI ; Xiangdong TANG
Journal of Biomedical Engineering 2014;31(1):210-213
The use of actigraphy, which can be used to estimate sleep-wake patterns from activity levels, has become common in sleep research. Actigraphy is a simple, cost-effective and non-invasive method for healthcare providers and researchers to assess patients sleep quality and screen for potential sleep disorders in recent years. But, there is no wide recognition and application of actigraphy in China up till now. This review summarized the application of actigraphy in evaluation of sleep and diagnosis of sleep disorders.
Actigraphy
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China
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Humans
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Sleep
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Sleep Wake Disorders
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diagnosis