1.Relationships Between Personality,Self-esteem and Mental Health in Armyman Serving at Aviation
Xiangang FENG ; Xiaoyuan ZHANG ; Yaning XIE
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective:To explore the relation between personality,self-esteem and mental health status of armyman serving at aviation.Methods:443 armyman were tested by Eysenck Personality Questionnaire(EPQ),Self-Esteem Scale(SES) and Symptom Checklist 90(SCL-90).Results:Neuroticism was positively correlated with the total average of SCL-90(r=0.641,P
2.Preliminary exploration of foreign students' probation in cardiovascular department
Xiangang MO ; Feng JIANG ; Li LI ; Wei ZHANG ; Jian FENG
Chinese Journal of Medical Education Research 2006;0(09):-
A summary will be made in this article concerning foreign seniors’ probation of Cardiology. These points as follows are vital to the successful teaching: making sufficient preparations before practice; analyzing the emphasis and difficulties, encouraging students to become the subject of class by making inquiry, doing physical examination by themselves and discussing the cases, paying great attention to the education of medical morality nurturance and correcting the students’ case records seriously.
3.An improved method for primary culture of neonatal mouse cardiomyocytes
Dan WU ; Jian FENG ; Xiangang MO ; Yingcai LIU
Chinese Journal of Comparative Medicine 2016;26(4):62-67
Objective To establish a stable and fast method for primary culture of mouse cardiomyocytes. Methods Dishes were coated with polylysine firstly.A two-step approach was used to isolate and digest mouse cardiomyocytes cells (0.25%trypsin in 4°C overnight and 0.5 mg/mL to 1.0 mg/mL collagenase +5 mg/mL albumin collagen digestion liquid in 37°C for short-time digestion), then the cardiomyocytes were purified through differential adhesion for 70 min and 5-bromodeoxyuridine ( BrdU) .The cell morphology was observed under an inverted microscope. The survival rate of cardiacmyocytes was detected by trypan-blue staining and their purity was identified by α-actinin immunofluorescence staining.Results The cardiomyocytes were in good shape and pulsed spontaneously.The survival rate of the cardiomyocytes reached 98%and the purity was 95%.Conclusions This method described in this study is an ideal method for primary culture of mouse cardiomyocytes with a high survival rate and high purity.
4.Development and Psychometric Validation of the Perinatal Bereavement Care Competence Scale for Midwives
Qiaoqiao SHEN ; Xiangping LUO ; Xiangang FENG ; Yulin GAO
Asian Nursing Research 2022;16(3):180-186
Purpose:
The aim of this paper is to develop a scale for measuring the perinatal bereavement care competence of midwives and assess its psychometric properties.
Methods:
The Perinatal Bereavement Care Competence Scale was developed in four phases. (1) Item generation: 75 items were formulated based on a literature review and interviews with midwives. (2) Delphi expert consultation: 15 experts evaluated whether the items were clear/appropriate/relevant to the questionnaire dimensions, and the items were optimized. (3) Pilot test: The comprehensibility, acceptability, and time required to complete the questionnaire by midwives were assessed. (4) Evaluation of reliability and validity: The scale was validated by initial item analysis, exploratory and confirmatory factor analyses, and internal consistency reliability and testeretest reliability.
Results:
The final scale consisted of six dimensions and 25 items: maintaining belief (three items), knowing (four items), being with (six items), preserving dignity (four items), enabling (five items), and self-adjustment (three items). Exploratory factor analysis yielded a six-factor structure that was consistent with the theoretical framework and explained 70.8% of the total variance. Confirmatory factor analysis indicated a good fit for the six-factor model. Cronbach's a for the scale was 0.931, and the test eretest reliability coefficient was 0.968.
Conclusion
The Perinatal Bereavement Care Competence Scale is a valid and reliable instrument for measuring the competence of midwives in caring for bereaved parents who have experienced perinatal loss.
5.Development of professional grief scale for medical postgraduate students and its reliability and validity
Ruzhi FENG ; Jia LI ; Jiayi LIANG ; Xiangang FENG ; Yulin GAO
Chinese Journal of Behavioral Medicine and Brain Science 2023;32(7):647-652
Objective:To develop a professional grief scale for medical postgraduate students(PGS-MPS) and test its reliability and validity.Methods:Based on the integrated model of professional grief, the initial item pool was formed after literature analysis, semi-structured interviews, group discussion, and 5 experts were invited to assess the relevance of the items and provided revision suggestion.A total of 506 valid questionnaires were collected.SPSS 25.0 and AMOS 26.0 were used to test its reliability and validity.Results:The PGS-MPS included 41 items, including the professional grief reaction subscale and disenfranchised grief subscale.The professional grief reaction subscale included emotional reaction (14 items), physiological and cognitive reaction (20 items), and the cumulative variance contribution rate of the two factors model was 52.908%.Disenfranchised grief subscale included 7 items, with a single dimension and a variance contribution rate of 51.730%.Confirmatory factor analysis indicated the model fitting well.The Cronbach’s α coefficients for the professional grief reaction subscale and disenfranchised grief subscale were 0.947 and 0.850, respectively.Conclusion:The PGS-MPS has good reliability and validity and can be used to evaluate professional grief of medical postgraduate students.
6.The mediating effect of emotion regulation strategy between inappropriate parenting styles and self-injury in medical students
Liping KUANG ; Xiangang FENG ; Simeng ZU ; Xiumei HE
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(3):226-229
Objective To explore the relationships between inappropriate parenting styles,emotional regulation strategies and self-injury.Methods A total of 1 096 medical students anonymously completed adolescents self-harm scale,emotion regulation scale (ERS) and the rejection and over-protection subscales of parental bonding instrument (PBI).Results The scores of paternal rejection,maternal rejection,paternal over-protection,maternal over-protection,cognitive reappraisal,expression suppression and self-injury were (4.3±3.3),(3.9±3.0),(5.7±3.3),(6.1±3.5),(36.1±6.7),(25.7±7.4) and (1.0±2.9),respectively.The scores of self-injury were positively correlated with the scores of paternal rejection,maternal rejection,paternal over-protection,maternal over-protection and expression suppression (r =0.08-0.20,P< 0.01),meanwhile negatively correlated with the scores of cognitive reappraisal(r=-0.10,P<0.01).Cognitive reappraisal mediated the relationship between parental rejection and self-injury,which accounted for 9.3%.Expression suppression mediated the relationship between parental rejection,parental over-protection and self-injury,which accounted for 14.5% and 17.9%,respectively.Conclusion The emotion regulation strategy act as a mediator between the inappropriate parental styles and self-injury in medical students.In addition,different emotion regulation strategies (cognitive reappraisal and expression suppression) play different roles in such relationship.
7.Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy.
Zhongmin TANG ; Yufen XIAO ; Na KONG ; Chuang LIU ; Wei CHEN ; Xiangang HUANG ; Daiyun XU ; Jiang OUYANG ; Chan FENG ; Cong WANG ; Junqing WANG ; Han ZHANG ; Wei TAO
Acta Pharmaceutica Sinica B 2021;11(11):3447-3464
The field of two-dimensional (2D) nanomaterial-based cancer immunotherapy combines research from multiple subdisciplines of material science, nano-chemistry, in particular nano-biological interactions, immunology, and medicinal chemistry. Most importantly, the "biological identity" of nanomaterials governed by bio-molecular corona in terms of bimolecular types, relative abundance, and conformation at the nanomaterial surface is now believed to influence blood circulation time, bio-distribution, immune response, cellular uptake, and intracellular trafficking. A better understanding of nano-bio interactions can improve utilization of 2D nano-architectures for cancer immunotherapy and immunotheranostics, allowing them to be adapted or modified to treat other immune dysregulation syndromes including autoimmune diseases or inflammation, infection, tissue regeneration, and transplantation. The manuscript reviews the biological interactions and immunotherapeutic applications of 2D nanomaterials, including understanding their interactions with biological molecules of the immune system, summarizes and prospects the applications of 2D nanomaterials in cancer immunotherapy.