1.Microsurgical treatment in aneurysms of anterior circulation
Yugang JIANG ; Minming ZHANG ; Jun XIANG
Chinese Journal of Microsurgery 2010;33(1):27-30,93
Objective To summarize the method and experience of microsurgical treatment of intracranial aneurysms in anterior circulation. Methods The clinical data, the skills and experience of 171 cases with aneurysmso of anterior circulation within the latest 2 years. Results One hundred and seventy-one patients under surgery, including 67 PCOA aneurysm, 56 ACoA aneurysm, 32 MCA aneurysm, 10 ICA aneurysm, OphA aneurysm and 3 haimess aneurysm. Accoring to Glasgow Prognostic Scale, there were 3 cases of grade Ⅰ, 6 cases of grade Ⅲ, 14 cases of grade Ⅳ and 148 cases of grade Ⅴ. Conclusion The key points to cure intracranial aneurysms successfully is favourable exposure and the skills of microsurgery; the factors of intluent surgery include forcejudgement in surgery, reasonable choice of aneurysm clips, correctly block in arterious.
3.Effect of Liuwei Dihuang decoction on secretion of testosterone in the testis leydig cells of senescence accelerated mouse
Jun-ping, CHENG ; Yong-Xiang, ZHANG
Bulletin of The Academy of Military Medical Sciences 2001;25(1):42-44
Objective:To study the effect of Liuwei Dihuang decoction (LW) on secretion of testosterone in the testis leydig cells of senescence accelerated mouse (SAM). Methods:The level of testosterone in the testis leydig cells of SAM with aging and the effect of LW on the secretion of testosterone were observed using cultured testis leydig cells in vitro.Results:The level of testosterone in the testis leydig cells of SAMP8 with aging was significantly decreased and showed a significant difference compared with age-matched SAMR1. Chronic administration of LW (2.5 and 5.0 g/kg) for 5 months significantly ameliorated the secretion of testosterone in SAMP8 compared with control group. Conclusions:The secretory function of testis leydig cells was reduced in SAMP8 with aging. LW ameliorated the secretion of testosterone in the testis leydig cells,indicating that LW could antagonize or delay the deterioration of the testis leydig cells in SAMP8.
4.Evaluation of left ventricular systolic function with tissue Doppler imaging in patients with type 2 diabetes
Jun ZHANG ; Juanjuan XIANG ; Yongsheng ZHU
Chinese Journal of Medical Imaging Technology 2009;25(10):1781-1784
Objective To evaluate the clinical application of the tissue Doppler imaging (TDI) in investigating the cardiac longitudinal systolic function in the patients with type 2 diabetes mellitus. Methods Forty-two patients with type 2 diabetes mellitus and 25 volunteers underwent TDI. The long axis myocardial peak systolic velocity (Sm), displacement (Dm) and strain rates (SRs) of 18 segments in different left ventricular walls were measured.Results The Dm and SRs of left ventricular wall in diabetic group dramatically decreased (P<0.01). Meanwhile, the diabetic combined hypertension group had much lower Sm of ventricular middle segments than the control group (P<0.05).Conclusion The stain rate and tissue tracking are sensitive and reliable to evaluate the early local cardiac systolic function in the patients with diabetes mellitus. TDI can be used as an noninvasive method to detect early systolic dysfunction.
5.Experimental studies on analgesic and anti-inflammation effects of aspirin -niacinamide-zinc complex (WUY)
Qisong PU ; Jun LEI ; Xiang ZHANG
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(12):-
AIM: To study the analgesia and anti-inflammation effects o f aspirin-niacinamide-zinc complex (WUY). METHODS: In this study , the mice ear swelling, vascular permeability increasing and rats’ paw edema w ere adopted to evaluate the anti-inflammable effects of WUY. And the analgesic effects of WUY were tested by writhing reaction and hot-plate method. R ESULTS: In high and low dose groups of WUY, the degrees of ear swelling were 3.3 and 2.8 mg, the Evans blue induced effusion were 3.1 and 1.2 mg?L -1, and the paw edema volume (1-4 h) were 0.21- 0.13 and 0.23- 0.08 ml, respectively. WUY ( 0.3 and 0.45 mmol?kg -1) prolonged incubation period of hot-plate reaction and showed marked i nhibition effects on writhing induced by acetic acid in mice. CONCLUSION : The analgesic and anti-inflammable effects of WUY are stronger than t hat of ASP.
6.Peripheral blood stem cell transplantation in the treatment of dilated cardiomyopathy: A 3-month follow-up in 42 cases
Tong ZHANG ; Chao LIU ; Jun YANG ; Xiang ZHANG ; Wen LI
Chinese Journal of Tissue Engineering Research 2007;0(16):-
AIM: Recent studies showed that stem cells could replace injured cardiomyocyte and increase the number of functional cardiomyocytes. Researching the pertinent literature in China Journal Full-text Database (CJFD) published between 2005 and 2008 indicated that the researches on stem cell transplantation in the treatment of primary dilated cardiomyopathy were few. This study investigated the therapeutic efficacy and security of peripheral blood stem cell transplantation in coronary artery in treatment of dilated cardiomyopathy and its effects on left ventricular function. METHODS: Forty-two patients with dilated cardiomyopathy between December 2006 and September 2007 were enrolled at the Department of Cardiology of First People's Hospital of Yunnan, including twenty-eight males and fourteen females, averagely aged (56?3) years. Inclusive criteria: patients with less than 65 years, left ventricular enlargement, and left ventricular ejection fraction (LVEF) ≤ 45%, and without coronary artery disease after coronary arteriongraphy. Informed consents were obtained from patients. Patients were divided into stem cell transplantation group (n=15) and control group (n=27) on the basis of whether being treated by stem cell transplantation. Patients in the stem cell transplantation group were consecutively administered granulocyte colony-stimulating factor (G-CSF) by hypodermic injection to stimulate bone marrow stem cells themselves based on conventional treatment for five days. Peripheral blood stem cell suspension was disassociated on the 6th day, and the collected suspension was injected into left anterior descending branch over the wire saccule tube for autologous peripheral blood stem cell transplantation. Patients in the control group were administered by conventional treatment of dilated cardiomyopathy. Security and adverse reaction were observed during the mobilization, collection and returning injection of peripheral blood stem cell by coronary artery. Morphous, cardiac function and motion index of left ventricle wall were evaluated using ultrasoundcardiogram before and 3 months after transplantation. Survival rate and incidence rate of heart incidents were compared. RESULTS: Three months after stem cell transplantation in coronary artery, there were a significant decrease in cardiac end-systolic volume (ESV), cardiac end-diastolic volume (EDV) and motion index of left ventricle wall, but a significant increase in LVEF(P
7.A clinical comparison of complete re-flow with partial re-flow on offectioh of Patients with MI accompany with HF's LVSF.
Tong ZHANG ; Jun YANG ; Xiang ZHANG ; Al ET ;
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective To explore the different effects of patiants with Myocardial infarction(MI)accompany with HF's LSVF and the prognosis between complete reftow and partial reflow.Methods 57 cases with MI accompany with HF were randomly divided into 2 groups:complete reflow group and partial reflow group.The two groups were done low-dose Dobutamine loading experiment seperately before operations.22 cases were treated by complete tallow using PCI,other 35 Patients were dealed with Partial reflow using PCI.To contrast the data of LVSF,WMSI,A/V and LVED between the two groups with UCG before and after PCI.Results The complete reflow group was obviously more arailable than the partial group.Conclusion The complete reflow can improve LVSF of the paticnts with MI accompany with HF.
8.Posterior wall reconstruction of external auditory canal and tympanoplasty after modified radical mastoidectomy.
Zhi-Gang ZHANG ; Xiang LIU ; Sui-Jun CHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(7):597-598
Adult
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Ear Canal
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Female
;
Hearing Loss, Conductive
;
surgery
;
Humans
;
Male
;
Mastoid
;
surgery
;
Middle Aged
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Postoperative Period
;
Tympanoplasty
9.Calcium-binding protein secretagogin is a novel neuroendocrine marker.
Wen-jun WANG ; Fan ZHANG ; Guo-xiang XU ; Chen CHEN
Chinese Journal of Pathology 2010;39(9):627-628
Adenoma
;
metabolism
;
Adrenal Cortex Neoplasms
;
metabolism
;
Biomarkers, Tumor
;
metabolism
;
Calcium-Binding Proteins
;
metabolism
;
Carcinoma, Neuroendocrine
;
metabolism
;
Humans
;
Lung Neoplasms
;
metabolism
;
Neuroendocrine Cells
;
metabolism
;
Neuroendocrine Tumors
;
metabolism
;
Secretagogins
;
Small Cell Lung Carcinoma
;
metabolism
10.Aesthetic restoration of full ceramic veneer by slip casting
Zaixi DENG ; Jun JIA ; Chunbao ZHANG ; Xiang SUN
Journal of Practical Stomatology 2009;25(4):595-597
Full ceramic prosthesis is becoming the main prosthetic development direction. As an important kind of full ceramic prosthesis, full ceramic veneer has not only natural cosmetic appearance and perfect biocompatibility, but also can preserve tooth structure as much as possible, which would be more easily accepted by patients for cosmetic prosthesis. Many methods, such as slip casting, die casting and CAD/CAM technology are available to make full ceramic veneer. All the methods have their own advantages and disadvantages. Slip casting is easy to be developed widely with low cost, so be used in practical work. In this article, the working process of full ceramic veneer, especially manufacture of removable dies, duplication of refractory models, were introduced, which was supposed to be beneficial for the technicians.