2.Isolation proliferation and characterization of endothelial progenitor cells from adult peripheral blood.
Xing-xiang WANG ; Jun-hui ZHU ; Jun-zhu CHEN
Chinese Journal of Applied Physiology 2005;21(1):94-95
Adult
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Cell Separation
;
methods
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Endothelial Cells
;
cytology
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Humans
;
Stem Cells
;
cytology
3.Calcium-binding protein secretagogin is a novel neuroendocrine marker.
Wen-jun WANG ; Fan ZHANG ; Guo-xiang XU ; Chen CHEN
Chinese Journal of Pathology 2010;39(9):627-628
Adenoma
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metabolism
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Adrenal Cortex Neoplasms
;
metabolism
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Biomarkers, Tumor
;
metabolism
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Calcium-Binding Proteins
;
metabolism
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Carcinoma, Neuroendocrine
;
metabolism
;
Humans
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Lung Neoplasms
;
metabolism
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Neuroendocrine Cells
;
metabolism
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Neuroendocrine Tumors
;
metabolism
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Secretagogins
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Small Cell Lung Carcinoma
;
metabolism
4.Studies on the Central Regulatory Mechanism of Acupuncture-moxibustion Treatment for Gastric Mucosal Injury
Juan XIANG ; Guo CHEN ; Fei LI ; Liting XIANG ; Ying CHEN ; Jun YU ; Zhou YANG ; Liang PENG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(12):1484-1487
This article provides the possible mechanism of acupuncture-moxibustion repair of gastric mucosal injury from central regulation and puts it forward that the nucleus of solitary tract is the primary regulation center for the injury repair and has the effect of collecting and integrating information. In addition, it is put forward that neural regulation is a main regulatory mechanism for the injury repair and besides, endocrine, immune and humoral regulations participates in the modulation and gastric mucosal repair involves a composite regulatory mechanism in which the central nervous system, neuroendocrine-immune network and neurohumoral regulation take part.
5.Contrast-enhanced ultrasound features and Nottingham prognostic index in patients with breast cancer
Yan DING ; Fengsheng ZHOU ; Jun CHEN ; Xiaqing XIANG ; Pengxi WU
Journal of Endocrine Surgery 2012;06(2):94-97
ObjectiveTo study the correlation between contrast-enhanced ultrasound (CEUS) features and Nottingham prognostic index (NPI) in patients with breast carcinoma. Methods The ultrasound features and microvascular imaging manifestation of 91 breast carcinomas confirmed by pathology were retrospectively analyzed.NPI was typically stratified into 3 major groups:NPI < 3.4 ( n =19 ), NPI:3.4-5.4 ( n =52 ) and NPI >5.4(n =21 ). Results With the increase of NPI, the rate of heterogeneous enhancement, perfusion defects, edge enhancement higher than center enhancement, and unclear border increased.The difference among the 3 groups had statistical significance (P < 0.05 ).There was no significant difference in enhancement order among the 3 groups ( P > 0.05 ).The lesions of the 3 groups were mainly “high enhancement” and there was no significant difference among the 3 groups ( P > 0.05 ).With the increase of NPI, the rate of early enhancement and late regression increased.The difference among the 3 groups had statistical significance ( P < 0.05 ).With the increase of NPI, the rate of enlarged and twisted vessels as well as peripheral vessel burr increased.There was significant difference among the 3 groups ( P < 0.05 ).ConclusionCEUS festures and microvescular architecture pattern of breast carcinoma are related to NPI, which is useful in predicating the prognosis of breast carcinoma.
6.On Teaching Methods of Fundamental Operations in Surgery and Animal Surgery
Ming LI ; Jun CHEN ; Fang LUO ; Zheng XIANG
Chinese Journal of Medical Education Research 2005;0(06):-
The course of fundamental operations in surgery is an important part of surgical teaching.It helps students to adapt to surgical practice quickly.During the teaching,there are some ways to improve teaching efficiency and quality,such as to know the new Chinese-English teaching material,the teaching purpose,the training of basic skills and aseptic principles of operation,the examination reform and regular teaching summery.
7.Posterior wall reconstruction of external auditory canal and tympanoplasty after modified radical mastoidectomy.
Zhi-Gang ZHANG ; Xiang LIU ; Sui-Jun CHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(7):597-598
Adult
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Ear Canal
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Female
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Hearing Loss, Conductive
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surgery
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Humans
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Male
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Mastoid
;
surgery
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Middle Aged
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Postoperative Period
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Tympanoplasty
8.Short-term clinical effect of K-Rod pedicle dynamic fixation system for multiple segmental lumbar degeneration
Yanchun XIE ; Liangbi XIANG ; Jun LIU ; Hailong YU ; Yu CHEN
Journal of Regional Anatomy and Operative Surgery 2015;24(6):654-656
Objective To discuss the short-term clinical effect of K-Rod pedicle dynamic fixation system for multiple segmental lumbar degeneration. Methods From January 2010 to October 2012,28 patients with multiple segmental lumbar degeneration who were accepted K-Rod pedicle dynamic fixation system were retrospectively reviewed. The short-term clinical effect were based on Oswestry disability index score,visual analogous scale ( VAS) ,improvement rate of low back pain,postoperative lumbar hyperextension, hyperbend X-ray film lumbar ROM value ( lumbar flexion mobility) ,average operation time, intraoperative blood loss. Results All of 28 cases were achieved 12 ~24 months follow-up,the difference of Oswestry disability index score and visual analogous scale ( VAS) between 12 months postoperatively and preoperatively were statistically significant,the improvement rate of low back pain was (87. 0 ± 2. 0)%,the average operation time was (99. 6 ± 16. 2) minutes,the average blood loss was (70. 5 ± 31. 5)mL,the average length of stay(ALOS) was (11. 2 ± 2. 6) days after sur-gery. Conclusion K-Rod pedicle dynamic fixation system in the treatment of multiple segmental lumbar degeneration can obtain satisfactory short-term clinical effect.
9.Atlas lateral mass screws combined with posterior Epistropheus pedicle screws for treatment of atlantoaxial joint instability
Liangbi XIANG ; Jun LIU ; Hailong YU ; Yu CHEN ; Yanchun XIE
Journal of Regional Anatomy and Operative Surgery 2015;24(6):640-642
Objective To discuss the clinical effect and the notes of atlas lateral mass screws combined with posterior epistropheus ped-icle screws for the treatment of atlantoaxial joint instability. Methods In our hospital from January 2006 to January 2011,48 cases of atlan-toaxial joint instability accepted operation of the atlas lateral mass screws combined with epistropheus pedicle screws were analyzed. Results All patients with follow-up time 12~24 months,an average of 17 months,were achieved primary healing and atlanto-axial intervertebral osse-ous healing. Besides postoperative neck pillow area pain improved and nerve function get a degree of recovery,there was no inner fixed damage cases. Complications of operation include venous plexus hemorrhage was in 2 cases,cervical occipital pain and numbness increase in 3 cases,cere-brospinal fluid leak in 2 cases,vertebral artery extrusion occlusion after cerebral ischemic symptoms in 1 case. Conclusion Combination of atlas lateral mass screws and posterior epistropheus pedicle screws technique is one of the effective means of treatment of atlantoaxial joint instabili-ty and can obtain satisfactory clinical effect. Standard operation performance is the key to reduce or even eliminate surgical complications.
10.Paraspinal approach and posterior median approach for one-stage decompression reconstruction in the treat-ment of thoracolumbar spine fracture and dislocation
Guihua YU ; Jun CHEN ; Fusheng XIANG ; Weixing SHI
Journal of Regional Anatomy and Operative Surgery 2016;25(3):208-211
Objective To explore the effect of paraspinal approach and posterior median approach for one -stage decompression recon-struction in the treatment of thoracolumbar spine fracture and dislocation .Methods From January 2012 to January 2014, 60 patients with thoracolumbar spine fracture and dislocation who were admitted and treated in our hospital were selected as the research objects .All patients received one-stage decompression reconstruction for treatment .According to the methods of approach , the patients were divided into the ob-servation group and the control group .The 30 cases in observation group were treated by paraspinal approach while the other 30 cases in con-trol group were treated by posterior median approach .Visual analogue score ( VAS) was applied .The status of surgery , recovery of centrum height, changes of Cobb angle as well as the occurrence rate of postoperative complications in the two groups were recorded .Results In the observation group, the operative time, time in bed and length of stay were (89.16 ±11.63) min, (39.75 ±8.69) h and (3.96 ±1.04) d respectively, which were shorter than those in the control group .The intraoperative blood loss was (89.64 ±13.62) mL which was lower than that in the control group and the difference was significant (P<0.05).One week after operation, the anterior and posterior height of centrum in the observation group increased significantly while Cobb angle significantly reduced .Compared with those before the treatment , the difference was significant (P<0.05).The maximum coronary diameter and maximum sagittal diameter of paraspinal muscles in the ob -servation group after the treatment were (48.96 ±5.34)mm and (18.16 ±6.74)mm respectively, which were significantly higher than those in the control group and the difference was significant (P<0.05).The incidence of lumbar and back pain in the observation group was 3.33%which was lower than 23.33%in the control group and the difference was statistically significant (P<0.05).Conclusion To carry out decompression reconstruction through paraspinal approach can reduce the the pain degree of patients and the incidence of lumbar and back pain after operation .