1.Understanding and controversy of the gastroesophageal junction adenocarcinoma.
Xiang-Hong ZHANG ; Qi-Zhang WANG
Chinese Journal of Oncology 2008;30(12):947-949
Adenocarcinoma
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classification
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pathology
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surgery
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therapy
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Cardia
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Chemotherapy, Adjuvant
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Esophageal Neoplasms
;
classification
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pathology
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surgery
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therapy
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Esophagectomy
;
methods
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Esophagogastric Junction
;
surgery
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Gastrectomy
;
methods
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Humans
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Neoplasm Staging
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Radiotherapy, Adjuvant
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Stomach Neoplasms
;
classification
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pathology
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surgery
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therapy
4.The effects of standing training with dynamic standing bed on functional recovery of hemiplegic patients
Qi CHEN ; Tong WANG ; Jinrong TANG ; Xiang WANG
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(04):-
Objective To investigate the effects of dynamic standing bed training on the functional recovery of hemiplegic patients. Methods Sixty hemiplegic patients with Barthel index score of 40 were randomized into a standing rehabilitation group and a control group. The patients in standing rehabilitation group were asked to take part in dynamic standing bed training in addition to drug treatment. Those in the control group were treated with medication only. After 1 to 2 weeks of treatment, the weight-bearing ability of the lower limbs, balance, muscle tone, trunk control and the cardiovascular response were evaluated and compared with those before the treatment. Results The scores of weight-bearing, balance, muscle tone and trunk control of the patients in the standing rehabilitation group were better improved than those in the control group. The changes of blood pressure and pulse of patients were reduced and within the range of safety after 2 weeks of training. Conclusion Dynamic standing bed training is beneficial for the functional recovery of hemiplegic patients. It is safe for the patients in terms of cardiovascular response.
5.Effect of Different Does of Simvastatin in Reducing Serum Lipid
Zhe QI ; Jilin CHEN ; Li FANG ; Julan XIANG ; Min WANG
Herald of Medicine 2001;(3):152-153
Objective:Comparing the effect of different doses of simvastatin in lowering the serum lipid.Methods:79 patients were randomized into group A and group B,and were given simvastatin 10 mg*d-1 (group A) and 20 mg*d-1 (group B),respectively for a total of 8 weeks.Results:Comparing with baseline,in group A,TC,TG,LDL-C were decreased by 23.4%,20.0% and 30.7%,respectively (P<0.01); HDL-C was increased by 17.5%.The content of serum TC,TG and LDL-C was decreased to the normal range in 12.8%,28.2% and 15.4% of the patients in group A.For the group B,TC,TG,LDL-C were decreased by 32.7%,22.8% and 42.8%,respectively (P<0.01); HDL-C was increased by 13.7%.The content of serum TC,TG and LDL-C was decreased to the normal range in 65.0%,57.5% and 65.0% of the group B patients.Conclusion:Oral intake of 20 mg of simvastatin once a day can effectively reduce the serum lipid.The patients can well tolerate and no obvious side effect was observed in our study.
6.Protective effect of taurine on HK-2 cells exposed to oxalate and calcium oxalate monohydrate crystal in vivo
Chengyang LI ; Jianfeng QI ; Xiang WANG ; Zhiwei TAO ; Yaoliang DENG
Chinese Journal of Urology 2013;(4):263-267
Objective To investigate the protective effect of taurine on HK-2 cells exposed to oxalate (Ox) and calcium oxalate monohydrate crystal (COM) in vivo.Methods HK-2 cells,a proximal tubular epithelial cell line,were cultured.Five groups were divided in this study:control group (only HK-2 cells) ; Ox and COM group (HK-2 cells + Ox + COM) ; Taurine group (HK-2 cells + Ox + COM + Taurine) ; Apocynin group (HK-2 cells + Ox + COM + Apocynin) ; Catalase group (HK-2 cells + Ox + COM +Catalase).After 6 hrs,the cultures medias from each group were tested for LDH,H2O2,8-isoprostane,and MCP-1 protein.Cellular expression of MCP-1 mRNA and P47phox mRNA were determined by reverse transcriptase-polymerase chain reaction.After 24 hrs,cells livability was investigated by MTT.Results Compared with the control,cells livability was reduced when exposed to Ox and COM (P < 0.05),Treatment with Taurine,Apocynin and Catalase significantly increased the cells livability (P < 0.05).Compared with the control,the expression of LDH,H2O2,8-isoprostane,and cellular expression of MCP-1 mRNA and P47phox mRNA were increased following exposure to Ox and COM (P<0.01,P<0.01,P<0.01,P<0.01,P <0.05).Treatment with Taurine,Apocynin and Catalase significantly reduced the expression of LDH,H2O2,8-isoprostane,as well as the cellular expression of MCP-1 mRNA.Expression of P47phox mRNA in Taurine group was not reduced significantly (P > 0.05).Conclusions This study showed that Taurine protected the HK-2 cells from oxidative injury exposed to Ox and COM by the pathway that may not be in relation to the inhibition of P47phox mRNA expression.
7.Study on the map of plasmid of Y. pestis in the R. opimus natural plague foci in Junggar Basin
Rong GUO ; Youquan XIN ; Xinhui WANG ; Zhizhen QI ; Xiang DAI
Chinese Journal of Microbiology and Immunology 2009;29(4):291-293
Objective To investigate the type of plasmid map of Y. pestis in the R. opimas natural plague loci in Junggar Basin. Methods A total of 39 plasmid DNA of Y. pestis which were isolated from the natural plague loci of Junggar Basin, Tianshan Mountain, Kunlun Mountain, Qinghai-Tibet Plateau and In-ner Mongolia were extracted by the methods of Kado and Liu. The plasmid map was analyzed by the methods of agarose gel eleetrophoretogram. Results Two types of plasmid map were found in 26 Y. pestis which were isolated from Junggar Basin. Of them 23 were 6 × 106, 45 × 106 and 65 × 106 type of plasmid map, and 3 were 6 × 106, 45 × 106 and 72 × 106 type. Conclusion There are two types of plasmid map in the R. opi-mus natural plague loci in Junggar Basin. One type, which is the dominant type in this area, is 6 × 106, 45 × 106 and 65 × 106 type. This type is also similar to the dominant plasmid map type of the nature plague loci of Tianshan Mountain, Kunlun Mountain, Qinghai-Tibet Plateau and Inner Mongolia. The other type is 6 × 106, 45 × 106 and 72 × 106 type, and this type is new plasmid map type of Y. pestis in our country.
10.A case of retroperitoneal fibrosis.
Xiang-Shan XU ; Yuan-Zhe JIN ; Qi WANG
Chinese Journal of Cardiology 2009;37(11):1047-1048